{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T21:05:59Z","timestamp":1773608759672,"version":"3.50.1"},"reference-count":46,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AR055612"],"award-info":[{"award-number":["R01AR055612"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AR055612"],"award-info":[{"award-number":["R01AR055612"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["arthroscopyjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Arthroscopy"],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>The purpose of this study was to objectively evaluate whether double\u2010bundle anterior cruciate ligament (ACL) reconstruction can better restore the normal translational and rotational laxities than the conventional single\u2010bundle ACL reconstruction among the reported biomechanical studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic literature search was conducted to identify in vitro and in vivo (intraoperative) biomechanical studies that compared the laxities (anterior or anteroposterior or rotational) between single\u2010 and double\u2010bundle ACL reconstructions. Because of large variability among the loading conditions and testing methods used to determine the rotational laxities among the studies, a meta\u2010analysis of rotational laxities was not feasible.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Seven in vitro and three in vivo studies were included in this analysis based on the predefined inclusion criteria. The overall mean differences calculated by the random effects model in anteroposterior laxity between the single\u2010bundle and double\u2010bundle ACL reconstruction techniques at 0\u00b0, 30\u00b0, 60\u00b0, and 90\u00b0 of flexion were 0.99 mm, 0.38 mm, 0.34 mm, and 0.07 mm, respectively. No statistically significant difference was noted between the 2 treatments at all flexion angles. Among the 9 studies that compared the rotational laxity of single\u2010bundle and double\u2010bundle ACL reconstructions, 4 reported that double\u2010bundle reconstruction can provide better rotational control than single\u2010bundle reconstruction. The other 5 studies could not identify any significant difference between the 2 reconstructions in terms of rotational laxity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Both single\u2010 and double\u2010bundle treatment options for ACL injury result in similar anteroposterior knee joint laxity at time 0. No conclusive evidence on the superiority of 1 reconstruction technique over the other in terms of rotation laxity can be obtained because of several variations in the experimental protocol and the kinematics used to measure the rotational laxity among the studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level III, meta\u2010analysis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.arthro.2010.12.003","type":"journal-article","created":{"date-parts":[[2011,6,23]],"date-time":"2011-06-23T06:49:00Z","timestamp":1308811740000},"page":"849-860","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["In Vitro and Intraoperative Laxities After Single\u2010Bundle and Double\u2010Bundle Anterior Cruciate Ligament Reconstructions"],"prefix":"10.1002","volume":"27","author":[{"given":"Hemanth R.","family":"Gadikota","sequence":"first","affiliation":[{"name":"Bioengineering Laboratory Department of Orthopaedic Surgery Massachusetts General Hospital and Harvard Medical School Boston Massachusetts U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong Keun","family":"Seon","sequence":"additional","affiliation":[{"name":"Bioengineering Laboratory Department of Orthopaedic Surgery Massachusetts General Hospital and Harvard Medical School Boston Massachusetts U.S.A."},{"name":"Department of Orthopaedic Chonnam National University Hwasun Hospital Jeonnam South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chih\u2010Hui","family":"Chen","sequence":"additional","affiliation":[{"name":"Bioengineering Laboratory Department of Orthopaedic Surgery Massachusetts General Hospital and Harvard Medical School Boston Massachusetts U.S.A."},{"name":"Department of Orthopaedic Surgery Taichung Veterans General Hospital Taichung City Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia\u2010Lin","family":"Wu","sequence":"additional","affiliation":[{"name":"Bioengineering Laboratory Department of Orthopaedic Surgery Massachusetts General Hospital and Harvard Medical School Boston Massachusetts U.S.A."},{"name":"Department of Orthopaedic Surgery Tri\u2010Service General Hospital National Defense Medical Center Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas J.","family":"Gill","sequence":"additional","affiliation":[{"name":"Bioengineering Laboratory Department of Orthopaedic Surgery Massachusetts General Hospital and Harvard Medical School Boston Massachusetts U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guoan","family":"Li","sequence":"additional","affiliation":[{"name":"Bioengineering Laboratory Department of Orthopaedic Surgery Massachusetts General Hospital and Harvard Medical School Boston Massachusetts 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