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Twenty patients have been followed up since their initial presentation before arthroplasty (group 1), and 20 patients were referred either for management of complications arising after prosthetic arthroplasty or for evaluation only (group 2).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Thirty\u2010seven patients received an intra\u2010articular pain pump (IAPP) delivering bupivacaine, and 3 patients had prominent suture anchors or tacks. Symptoms related to chondrolysis developed in patients at a mean of 9.8 months (range, 1 to 34 months) after the index procedure. Radiographs showed joint space obliteration in 30 of 40 patients at most recent follow\u2010up or before arthroplasty. Of the patients receiving an IAPP delivering bupivacaine, the majority received 0.5% with epinephrine. Higher bupivacaine dose (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .05) and female gender (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .05) were associated with a longer interval to onset of symptoms. In addition, a shorter interval to onset of symptoms predicted the need for subsequent surgery (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .05) and a shorter interval to second\u2010look arthroscopy (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Post\u2010arthroscopic glenohumeral chondrolysis is a devastating and rapidly evolving condition that most often strikes young patients. The use of IAPPs delivering local anesthetics should be abandoned because nearly all cases of glenohumeral chondrolysis in this series were associated with their use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level IV, therapeutic case series.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.arthro.2013.04.007","type":"journal-article","created":{"date-parts":[[2013,6,26]],"date-time":"2013-06-26T17:16:03Z","timestamp":1372266963000},"page":"1135-1141","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Glenohumeral Chondrolysis: Part I\u2014Clinical Presentation and\u00a0Predictors of Disease Progression"],"prefix":"10.1002","volume":"29","author":[{"given":"Samer S.","family":"Hasan","sequence":"first","affiliation":[{"name":"Cincinnati SportsMedicine and Orthopaedic Center Cincinnati Ohio U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cassie M.","family":"Fleckenstein","sequence":"additional","affiliation":[{"name":"Cincinnati SportsMedicine and Orthopaedic Center Cincinnati Ohio U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,7,1]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002640100291"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546507304136"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.D.02158"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2007.03.092"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-006-0112-z"},{"key":"e_1_2_3_7_1","first-page":"E34","article-title":"Severe chondrolysis of the glenohumeral joint after shoulder thermal capsulorrhaphy","volume":"38","author":"Coobs 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