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Predisposing genetic factors and modern\u2010life environmental factors, such as diet, excessive physical exercise, or the absence of any physical exercise, in addition to injuries that can occur, all contribute to the onset and development of chronic degenerative diseases such as osteoarthritis. Regenerative medicine focuses on the repair, replacement, or regeneration of cells, tissues, or organs to restore impaired function from any cause, including congenital defects, disease, and trauma.<\/jats:p>","DOI":"10.1016\/j.arthro.2014.11.031","type":"journal-article","created":{"date-parts":[[2015,2,7]],"date-time":"2015-02-07T19:32:03Z","timestamp":1423337523000},"page":"777-783","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":54,"title":["Biologic Enhancement of Cartilage Repair: The Role of Platelet\u2010Rich Plasma and Other Commercially Available Growth Factors"],"prefix":"10.1002","volume":"31","author":[{"given":"Ramon","family":"Cugat","sequence":"first","affiliation":[{"name":"Division of Medicine and Regenerative Surgery Garcia Cugat Foundation and CEU Cardenal Herrera University Valencia Spain"},{"name":"Mutualidad de Futbolistas, Royal Spanish Football Federation Barcelona Spain"},{"name":"Department of 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