{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:57:05Z","timestamp":1791421025791,"version":"4.3.3"},"reference-count":29,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2015,5,13]],"date-time":"2015-05-13T00:00:00Z","timestamp":1431475200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2015,5,13]],"date-time":"2015-05-13T00:00:00Z","timestamp":1431475200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2015,5,13]],"date-time":"2015-05-13T00:00:00Z","timestamp":1431475200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","arthroscopyjournal.org","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Arthroscopy"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To describe and compare comorbidity among anterior cruciate ligament (ACL)\u2013reconstructed patients and a gender\u2010 and age\u2010matched group without ACL injury. Furthermore, we sought to evaluate the impact of comorbid diseases on the risk of ACL revision surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This case\u2010control study included 13,443 unilateral primary ACL\u2010reconstructed patients from the Danish Knee Ligament Reconstruction Register matched on gender and age with a comparison group without ACL injury. Information on medical comorbid conditions was obtained from the Danish National Registry of Patients. The prevalence of all comorbid conditions was described for ACL\u2010reconstructed patients and the comparison group in terms of (1) the Charlson Comorbidity Index (CCI); (2)\n                      <jats:italic>International Classification of Diseases, Tenth Revision<\/jats:italic>\n                      disease chapters; and (3) more common chronic diseases in a younger population. Finally, we assessed the risk of ACL revision surgery according to the more common chronic diseases in a younger population, using Cox regression analysis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Although we found a large variety of diseases present among ACL\u2010reconstructed patients, the percentage of patients with a CCI equal to 0 was high in both groups. ACL\u2010reconstructed patients generally had a slightly lower prevalence of almost all\n                      <jats:italic>International Classification of Diseases, Tenth Revision<\/jats:italic>\n                      \u2013classified comorbid disease groups compared with the comparison group without ACL injury. As expected, the prevalence of most diseases increased slightly with rising age. Furthermore, we found that having back pain or diseases of the back did alter the risk of revision surgery.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>ACL\u2010reconstructed patients are found to be generally healthy individuals with a low prevalence of serious and chronic diseases compared with an age\u2010 and gender\u2010matched control group from the general population. A large variety of diseases are present in the ACL\u2010reconstructed group but with very low prevalence rates and low CCIs, indicating that the severity of their illness is limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level III, case\u2010control study.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.arthro.2015.03.020","type":"journal-article","created":{"date-parts":[[2015,5,13]],"date-time":"2015-05-13T20:48:56Z","timestamp":1431550136000},"page":"1741","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Comorbidities in Patients With Anterior Cruciate Ligament Reconstruction Compared With Matched Controls Without Anterior Cruciate Ligament Injury From Danish Registries"],"prefix":"10.1002","volume":"31","author":[{"given":"Lene","family":"Rahr\u2010Wagner","sequence":"first","affiliation":[{"name":"Division of Sportstrauma Department of Orthopaedic Surgery Aarhus University Hospital Aarhus Denmark"},{"name":"Department of Clinical Epidemiology Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theis Muncholm","family":"Thillemann","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Lind","sequence":"additional","affiliation":[{"name":"Division of Sportstrauma Department of Orthopaedic Surgery Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alma Becic","family":"Pedersen","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,5,13]]},"reference":[{"key":"e_1_2_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(02)00585-1"},{"key":"e_1_2_3_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2007.01036.x"},{"key":"e_1_2_3_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6603717"},{"key":"e_1_2_3_5_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.93B2.25629"},{"key":"e_1_2_3_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2013.246"},{"key":"e_1_2_3_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-008-0654-3"},{"key":"e_1_2_3_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546512446000"},{"key":"e_1_2_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2011.11.024"},{"key":"e_1_2_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2012.09.009"},{"key":"e_1_2_3_11_2","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S45752"},{"key":"e_1_2_3_12_2","doi-asserted-by":"publisher","DOI":"10.1177\/1403494810387965"},{"key":"e_1_2_3_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/00008469-200506000-00002"},{"key":"e_1_2_3_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/1403494811401482"},{"key":"e_1_2_3_15_2","unstructured":"World Health Organization. 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