{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T12:52:47Z","timestamp":1790340767454,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,9,18]],"date-time":"2015-09-18T00:00:00Z","timestamp":1442534400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2015,9,18]],"date-time":"2015-09-18T00:00:00Z","timestamp":1442534400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2015,9,18]],"date-time":"2015-09-18T00:00:00Z","timestamp":1442534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","arthroscopyjournal.org","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Arthroscopy"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To (1) determine whether standard clinical muscle fatty infiltration and atrophy assessment techniques using a single image slice for patients with a rotator cuff tear (RCT) are correlated with 3\u2010dimensional measures in older individuals (60+ years) and (2) to determine whether age\u2010associated changes to muscle morphology and strength are compounded by an RCT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Twenty older individuals were studied: 10 with an RCT of the supraspinatus (5 men and 5 women) and 10 matched controls. Clinical imaging assessments (Goutallier and Fuchs scores and cross\u2010sectional area ratio) were performed for participants with RCTs. Three\u2010dimensional measurements of rotator cuff muscle and fat tissues were obtained for all participants using magnetic resonance imaging (MRI). Isometric joint moment was measured at the shoulder.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There were no significant associations between single\u2010image assessments and 3\u2010dimensional measurements of fatty infiltration for the supraspinatus and infraspinatus muscles. Compared with controls, participants with RCTs had significantly increased percentages of fatty infiltration for each rotator cuff muscle (all\n                      <jats:italic>P<\/jats:italic>\n                      \u2264 .023); reduced whole muscle volume for the supraspinatus, infraspinatus, and subscapularis muscles (all\n                      <jats:italic>P<\/jats:italic>\n                      \u2264 .038); and reduced fat\u2010free muscle volume for the supraspinatus, infraspinatus, and subscapularis muscles (all\n                      <jats:italic>P<\/jats:italic>\n                      \u2264 .027). Only the teres minor (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0= .017) fatty infiltration volume was significantly greater\u00a0for participants with RCTs. Adduction, flexion, and external rotation strength (all\n                      <jats:italic>P<\/jats:italic>\n                      \u2264 .021) were significantly reduced for participants with RCTs, and muscle volume was a significant predictor of strength for all comparisons.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Clinical scores using a single image slice do not represent 3\u2010dimensional muscle measurements. Efficient methods are needed to more effectively capture 3\u2010dimensional information for clinical applications. Participants with RCTs had increased fatty infiltration percentages that were likely driven by muscle atrophy rather than increased fat volume. The significant association of muscle volume with strength production suggests that treatments to preserve muscle volume should be pursued for older patients with RCTs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level II, diagnostic study, with development of diagnostic criteria on the basis of consecutive patients with universally applied reference gold standard.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.arthro.2015.06.035","type":"journal-article","created":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T14:46:52Z","timestamp":1443710812000},"page":"128-139","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":97,"title":["Assessments of Fatty Infiltration and Muscle Atrophy From a Single Magnetic Resonance Image Slice Are Not Predictive of 3\u2010Dimensional Measurements"],"prefix":"10.1002","volume":"32","author":[{"given":"Meghan E.","family":"Vidt","sequence":"first","affiliation":[{"name":"Department of Kinesiology University of Waterloo Waterloo Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"II","given":"Anthony C.","family":"Santago","sequence":"additional","affiliation":[{"name":"Virginia Tech\u2010Wake Forest University School of Biomedical Engineering and Sciences Winston\u2010Salem North Carolina U.S.A."},{"name":"Department of Mechanical and Aerospace Engineering North Carolina State University Raleigh North Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J.","family":"Tuohy","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Wake Forest School of Medicine Winston\u2010Salem North Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary G.","family":"Poehling","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Wake Forest School of Medicine Winston\u2010Salem North Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael T.","family":"Freehill","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Wake Forest School of Medicine Winston\u2010Salem North Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert A.","family":"Kraft","sequence":"additional","affiliation":[{"name":"Virginia Tech\u2010Wake Forest University School of Biomedical Engineering and Sciences Winston\u2010Salem North Carolina U.S.A."},{"name":"Department of Health and Exercise Science Wake Forest School of Medicine Winston\u2010Salem North Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony P.","family":"Marsh","sequence":"additional","affiliation":[{"name":"Virginia Tech\u2010Wake Forest University School of Biomedical Engineering and Sciences Winston\u2010Salem North Carolina U.S.A."},{"name":"Department of Health and Exercise Science Wake Forest School of Medicine Winston\u2010Salem North Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric J.","family":"Hegedus","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy High Point University High Point North Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael E.","family":"Miller","sequence":"additional","affiliation":[{"name":"Department of Biostatistical Sciences Wake Forest School of Medicine Winston\u2010Salem North Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine R.","family":"Saul","sequence":"additional","affiliation":[{"name":"Department of Mechanical and Aerospace Engineering North Carolina State University Raleigh North Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,9,18]]},"reference":[{"key":"e_1_2_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2008.05.003"},{"key":"e_1_2_2_3_2","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.E.00835"},{"key":"e_1_2_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1058-2746(99)90148-9"},{"key":"e_1_2_2_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp0800814"},{"key":"e_1_2_2_6_2","first-page":"78","article-title":"Fatty muscle degeneration in cuff ruptures. 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