{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T21:53:04Z","timestamp":1783720384161,"version":"3.55.0"},"reference-count":37,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T00:00:00Z","timestamp":1536105600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T00:00:00Z","timestamp":1536105600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T00:00:00Z","timestamp":1536105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T00:00:00Z","timestamp":1536105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["arthroscopyjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Arthroscopy"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the functional outcome of using chitosan\u2010based material in our patients after 2\u00a0years of follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Nonarthritic nondysplastic femoroacetabular impingement patients with an acetabular chondral lesion, 18 to 55\u00a0years of age, were included for arthroscopic repair between May 2013 and July 2015. Full\u2010thickness chondral defects \u22652\u00a0cm\n                      <jats:sup>2<\/jats:sup>\n                      were filled with chitosan\u2010based implant after microfractures. Follow\u2010up consisted of alpha angle assessment and clinical outcome in the form of the Non Arthritic Hip Score (NAHS), International Hip Outcome Tool 33 (iHOT33), Hip Outcome Score of Activities of Daily Living (HOS\u2010ADL), and Hip Outcome Score of Sports Specific Scale (HOS\u2010SSS).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Twenty\u2010three patients were included. The mean follow\u2010up was 38.4 \u00b1 7.0\u00a0months (range, 24\u201050\u00a0months). The mean defect size was 3.5 \u00b1 1.0\u00a0cm\n                      <jats:sup>2<\/jats:sup>\n                      , principally involving zone 2 and to a lesser extent in zones 1 and 3. Using femoroplasty, the alpha angle was corrected from a mean 70.5 \u00b1 6.3\u00b0 to 44.3 \u00b1 4.9\u00b0 (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0= .00001). Significant improvement occurred comparing the preoperative to the first\u2010year postoperative patient\u2010reported outcomes:\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0= .00001 for the NAHS,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0= .00004 for the iHOT33,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0= .00005 for the HOS\u2010ADL, and\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0= .0002 for the HOS\u2010SSS. No statistically significant change has been observed in the patient\u2010reported outcomes obtained at the endpoint when compared with the first\u2010year values (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0= .13 for the NAHS,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0= .21 for the HOS\u2010ADL, and\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0= .29 for the HOS\u2010SSS), except for the iHOT33, which showed further significant improvement (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0= .02). Up to 91% of the patients met or exceeded the minimal clinically important difference. One patient needed total hip arthroplasty. Perineal hypoesthesia occurred in 3 patients, who recovered within 2 to 6\u00a0weeks, and 1 patient needed a prolonged physiotherapy program for postoperative muscular stiffness.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      The arthroscopic combined treatment of microfractures and chitosan\u2010based scaffold has maintained satisfactory clinical outcomes in 91% of the patients with a large (\u22652\u00a0cm\n                      <jats:sup>2<\/jats:sup>\n                      ) full\u2010thickness acetabular chondral defect associated with femoroacetabular impingement at a mean follow\u2010up of 38.4\u00a0months. The study could not definitely draw any conclusion regarding the safety of chitosan\u2010based material for use in the hip joint.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level IV, case series.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.arthro.2018.06.037","type":"journal-article","created":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T21:16:40Z","timestamp":1536182200000},"page":"2821-2828","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":34,"title":["Arthroscopic Repair of Acetabular Cartilage Lesions by Chitosan\u2010Based Scaffold: Clinical Evaluation at Minimum 2\u00a0Years Follow\u2010up"],"prefix":"10.1002","volume":"34","author":[{"given":"Mahmoud Fathy","family":"Tahoun","sequence":"first","affiliation":[{"name":"Department of Orthopedics Menoufia University Egypt"},{"name":"Department of Orthopedics Parc de Salut Mar Universitat Aut\u00f2noma de Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Tey","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Parc de Salut Mar Universitat Aut\u00f2noma de Barcelona Barcelona Spain"},{"name":"Hip Unit iMove Traumatologia Cl\u00ednica Mitrestorres Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas","family":"Mas","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Hospital Vistahermosa Alicante Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taher","family":"Abd\u2010Elsattar Eid","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Menoufia University Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan Carles","family":"Monllau","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Parc de Salut Mar Universitat Aut\u00f2noma de Barcelona Barcelona 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