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Sixteen healthy individuals were recruited and underwent knee magnetic resonance imaging and biomechanical assessment during a drop\u2010landing task. T1\u03c1 cartilage relaxation times were calculated for the medial femur and tibia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      ACLR patients exhibited increased peak vertical ground reaction force (VGRF), VGRF impulse, peak knee flexion moment (KFM), and KFM impulse from 6\u00a0months to 3\u00a0years (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .001 for each). Although the ACLR knees showed significantly lower peak VGRF and KFM at 6\u00a0months (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .001 for both) when compared with the controls, there were no significant differences at 3\u00a0years. At 3\u00a0years, ACLR patients showed higher T1\u03c1 values over the medial femur (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .001) and tibia (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0= .012) when compared with their preoperative values and with healthy control values. Within the ACLR group, side\u2010to\u2010side differences in peak VGRF and sagittal knee biomechanics at 6\u00a0months were associated with increased T1\u03c1 values from baseline to 3\u00a0years.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The results of this longitudinal study show that landing biomechanics are altered after ACLR but biomechanical abnormalities tend to recover at 3\u00a0years after ACLR. Differences in lower\u2010extremity mechanics during a landing task at 6\u00a0months may be associated with cartilage degeneration at 3\u00a0years after anterior cruciate ligament injury and reconstruction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level II, prospective trial.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.arthro.2018.07.033","type":"journal-article","created":{"date-parts":[[2018,11,22]],"date-time":"2018-11-22T17:54:01Z","timestamp":1542909241000},"page":"511-520","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":67,"title":["Abnormal Biomechanics at 6\u00a0Months Are Associated With Cartilage Degeneration at 3\u00a0Years After Anterior Cruciate Ligament Reconstruction"],"prefix":"10.1002","volume":"35","author":[{"given":"Tomohiro","family":"Shimizu","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery University of California San Francisco San Francisco California U.S.A."},{"name":"Department of Orthopaedic Surgery Faculty of Medicine and Graduate School of Medicine Hokkaido University Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Samaan","sequence":"additional","affiliation":[{"name":"Musculoskeletal Quantitative Imaging Research Group Department of Radiology and Biomedical Imaging University of California San Francisco San Francisco California U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew S.","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Musculoskeletal Quantitative Imaging Research Group Department of Radiology and Biomedical Imaging University of California San Francisco San Francisco California U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Pedoia","sequence":"additional","affiliation":[{"name":"Musculoskeletal Quantitative Imaging Research Group Department of Radiology and Biomedical Imaging University of California San Francisco San Francisco California U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard B.","family":"Souza","sequence":"additional","affiliation":[{"name":"Musculoskeletal Quantitative Imaging Research Group Department of Radiology and Biomedical Imaging University of California San Francisco San Francisco California U.S.A."},{"name":"Department of Physical Therapy and Rehabilitation Science University of California San Francisco San Francisco California U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojuan","family":"Li","sequence":"additional","affiliation":[{"name":"Musculoskeletal Quantitative Imaging Research Group Department of Radiology and Biomedical Imaging University of California San Francisco San Francisco California U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. 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