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The inclusion criteria were as follows: 5 or more consecutive patients who underwent ASCR for IRCTs; clinical outcome measures reported at a minimum follow\u2010up of 12\u00a0months; and magnetic resonance imaging assessment at a minimum follow\u2010up of 6\u00a0months. The methodologic quality was evaluated using the Methodological Index for Non\u2010randomized Studies (MINORS). A narrative synthesis of data was performed. Mean outcome improvements were compared with minimal clinically important differences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We identified 7 eligible studies that included 344 shoulders in 338 patients who underwent ASCR for IRCTs (all Level IV studies). The mean MINORS score was 12.3 \u00b1 1.60. Of the 7 studies, 5 had a high risk of bias (MINORS score \u226412): 2 studies using only fascia lata autograft and 3 studies using only human dermal allograft. The mean age of patients ranged from 59.4 to 66.9\u00a0years. The mean follow\u2010up time ranged from 12 to 48\u00a0months. All studies reported statistically significant and clinically important mean improvements in active elevation (range of means, 28\u00b0\u201056\u00b0), the Constant score (range of means, 12\u201047.1 points), or the American Shoulder and Elbow Surgeons score (range of means, 29.3\u201056 points). In total, 218 shoulders underwent postoperative magnetic resonance imaging. The graft tear rate reported in studies using fascia lata autograft (181 shoulders) ranged from 5% to 32%, whereas the values reported in studies using human dermal allograft (37 shoulders) ranged from 20% to 75%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>ASCR using either fascia lata autograft or human dermal allograft leads to significant and clinically important improvements in clinical outcomes in IRCT patients at 12\u00a0months or later.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level IV, systematic review of Level IV studies.<\/jats:p>\n                  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