{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T21:15:06Z","timestamp":1773609306648,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T00:00:00Z","timestamp":1594684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T00:00:00Z","timestamp":1594684800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T00:00:00Z","timestamp":1594684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T00:00:00Z","timestamp":1594684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000312","name":"Joseph Rowntree Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000312","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013673","name":"JRF","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013673","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013673","name":"JRF","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013673","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["arthroscopyjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Arthroscopy"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the influence of trochlear dysplasia on clinical outcomes after autologous chondrocyte implantation (ACI) for the treatment of large cartilage lesions in the patellofemoral joint (PFJ) with a minimum of 2 years\u2019 follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed a retrospective review of prospectively collected data of all patients submitted to cartilage repair with ACI for focal cartilage defects in the PFJ by a single surgeon. Patient factors, lesion morphology, and preoperative and postoperative patient\u2010reported outcome measures including the Knee Injury and Osteoarthritis Score, Lysholm score, Tegner activity level, and International Knee Documentation Committee Subjective Knee Evaluation Form score were collected. Two independent observers assessed preoperative imaging to determine the presence and grade of trochlear dysplasia. Patients were stratified into 2 groups based on the presence or absence of trochlear dysplasia. Patients without trochlear dysplasia served as controls. Patients were matched 1:1 for sex, age, body mass index, lesion size, and location.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Forty\u2010six patients who underwent ACI in the PFJ with a mean follow\u2010up period of 3.7 \u00b1 1.9 years (range, 2\u20109 years) were enrolled in this study (23 in the trochlear dysplasia group vs 23 in the normal trochlea group). The patients\u2019 mean age was 30.1 \u00b1 8.8 years. Patient\u2010reported outcome measures at final follow\u2010up did not differ between the 2 groups (\n                      <jats:italic>P<\/jats:italic>\n                      &gt; .05). No difference in failure rates was seen between the 2 groups (n\u00a0= 1 [4.3%] vs n\u00a0= 1 [4.3%],\n                      <jats:italic>P<\/jats:italic>\n                      &gt; .999). Additionally, no difference in clinical outcomes was seen between patients with high\u2010grade dysplasia (19 patients; Dejour types B\u2010D) and patients without dysplasia (19 patients) (\n                      <jats:italic>P<\/jats:italic>\n                      &gt; .05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>ACI in the PFJ provides favorable outcomes even in patients with trochlear dysplasia, which are comparable to those in patients with normal trochlear anatomy. Thus, trochlear dysplasia seems to not influence the clinical outcomes of ACI in the PFJ.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level III, retrospective comparative trial.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.arthro.2020.07.012","type":"journal-article","created":{"date-parts":[[2020,7,15]],"date-time":"2020-07-15T12:34:22Z","timestamp":1594816462000},"page":"3019-3027","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Trochlear Dysplasia Does Not Affect the Outcomes of Patellofemoral Autologous Chondrocyte\u00a0Implantation"],"prefix":"10.1002","volume":"36","author":[{"given":"Alexandre","family":"Barbieri Mestriner","sequence":"first","affiliation":[{"name":"Cartilage Repair Center Brigham and Women\u2019s Hospital Harvard Medical Center Boston Massachusetts U.S.A."},{"name":"Universidade Federal de S\u00e3o Paulo\u2013Escola Paulista de Medicina S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jakob","family":"Ackermann","sequence":"additional","affiliation":[{"name":"Sports Medicine Center Massachusetts General Hospital Boston Massachusetts U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz Felipe","family":"Morlin Ambra","sequence":"additional","affiliation":[{"name":"Cartilage Repair Center Brigham and Women\u2019s Hospital Harvard Medical Center Boston Massachusetts U.S.A."},{"name":"Universidade Federal de S\u00e3o Paulo\u2013Escola Paulista de Medicina S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos Eduardo","family":"Franciozi","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo\u2013Escola Paulista de Medicina S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fl\u00e1vio","family":"Faloppa","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo\u2013Escola Paulista de Medicina S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas H.","family":"Gomoll","sequence":"additional","affiliation":[{"name":"Hospital for Special Surgery New York New York U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,7,14]]},"reference":[{"key":"e_1_2_2_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10544-017-0170-7"},{"key":"e_1_2_2_3_2","first-page":"CD010675","article-title":"Surgical interventions (microfracture, drilling, mosaicplasty, and allograft transplantation) for treating isolated cartilage defects of the knee in adults","volume":"9","author":"Gracitelli G.C.","year":"2016","journal-title":"Cochrane Database Syst 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