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Study quality was assessed by two independent reviewers. We calculated standardized mean difference (SMD) from baseline to follow\u2010up in each trial arm, preferably at 12 months follow\u2010up. Between\u2010study heterogeneity of outcomes, small\u2010study effects and rates of retear were assessed. Meta\u2010regression was performed to estimate associations between prespecified variables and clinical and structural outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Outcomes in 64 RCT and 19 PCS trial arms were analyzed. Median age was 59 years. There was substantial between\u2010study heterogeneity in clinical outcomes (SMD range: .42 to 6.44;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u00a0= 93% in RCT, 88% in PCS) and summary estimates were not calculated. On the basis of multivariate analysis, better clinical outcome was associated with lower (worse) mean outcome value at baseline, smaller tear size, and lower proportion of large\u2010massive tears (\n                      <jats:italic>R<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u00a0= 56 and 44%, respectively). Overall retear rate at median 13\u2010month follow\u2010up was 19.9% (interquartile range: 10\u201030). Higher mean age together with larger tear size and higher proportion of large\u2010massive tears were associated with increased retear rates (\n                      <jats:italic>R<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u00a0= 33% and 58%, respectively). Clinical outcome was not significantly related to rate of retear.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Studies with lower mean outcome values at baseline and predominantly small\u2010 to medium\u2010sized tears reported better clinical outcomes. Studies with higher mean age and a predominance of large\u2010massive tears had significantly increased retear rates, but retear rates were not associated with clinical outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level II, meta\u2010analysis of level I and II studies<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.arthro.2021.08.019","type":"journal-article","created":{"date-parts":[[2021,8,24]],"date-time":"2021-08-24T23:12:11Z","timestamp":1629846731000},"page":"967","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Better Short\u2010Term Outcomes After Rotator Cuff Repair in Studies With Poorer Mean Shoulder Scores and Predominantly Small to Medium\u2010Sized Tears at Baseline: A Systematic Review and 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