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Demographic, clinical, range of motion (ROM), and patient\u2010reported outcome measure (PROM) data were collected. Interventions were compared via arm\u2010based Bayesian network meta\u2010analysis in a random\u2010effects model and treatments ranked via surface under the cumulative ranking curves with respect to 3 domains: pain, PROMs, and ROM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 35 studies comprising 3,643 shoulders (42% female, age 50 \u00b1 5 years) were included. Arthroscopic decompression with acromioplasty ranked much greater than arthroscopic decompression alone for pain relief and PROM improvement, but the difference in absolute PROMs was not statistically significant. Corticosteroid injection (CSI) alone demonstrated inferior outcomes across all 3 domains (pain, PROMs, and ROM) with low cumulative rankings. Physical therapy (PT) with CSI demonstrated moderate\u2010to\u2010excellent clinical improvement across all 3 domains whereas PT alone demonstrated excellent ROM and low\u2010moderate outcomes in pain and PROM domains. PT with nonsteroidal anti\u2010inflammatory drugs or alternative therapies ranked highly for PROM outcomes and moderate for pain and ROM domains. Finally, platelet\u2010rich plasma injections demonstrated moderate outcomes for pain, forward flexion, and abduction with very low\u2010ranking outcomes for PROMs and external rotation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Arthroscopic decompression with acromioplasty and PT demonstrated superior outcomes whereas CSI demonstrated poor outcomes in all 3 domains (pain, PROMs, and ROM). For patients with significant symptoms, the authors recommend PT with CSI as a first\u2010line treatment, followed by acromioplasty and PT if conservative treatment fails. For patients with symptoms limited to 1 to 2 domains, the authors recommend a shared decision\u2010making approach focusing on treatment rankings within domains pertinent to individual patient symptomatology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>I, systematic review and network meta\u2010analysis of Level I studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.arthro.2022.02.008","type":"journal-article","created":{"date-parts":[[2022,2,18]],"date-time":"2022-02-18T21:03:06Z","timestamp":1645218186000},"page":"2511-2524","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Physical Therapy Combined With Subacromial Cortisone Injection Is a First\u2010Line Treatment Whereas Acromioplasty With Physical Therapy Is Best if Nonoperative Interventions Fail for the Management of 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