{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T12:09:22Z","timestamp":1774008562029,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T00:00:00Z","timestamp":1647907200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T00:00:00Z","timestamp":1647907200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T00:00:00Z","timestamp":1647907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T00:00:00Z","timestamp":1647907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100007307","name":"Arthrex","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007307","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008894","name":"Stryker","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008894","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["arthroscopyjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Arthroscopy"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>The purpose of this study was to evaluate the impact of patient sex on outcomes after treatment of osteochondritis dissecans (OCD) lesions of the knee through a systematic review of current evidence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This review was conducted according to the PRISMA guidelines using the PubMed, PubMed Central, Embase, Ovid Medline, Cochrane Libraries, and the Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases. Relevant outcomes included functional (e.g., International Knee Documentation Committee and Subjective Knee Evaluation, Lysholm Knee Score) and clinical outcomes (e.g., symptom\/pain resolution, reoperation rates) for males and females after operative or nonoperative treatment of knee OCD lesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Ten articles with a total of 691 (73%) males and 260 (27%) females were included. Mean age ranged from 11.3 \u00b1 2.1 years to 34.5 \u00b1 10.3 years, and follow\u2010up ranged from 6 months to 16.3 years. In four studies reporting functional outcomes, no significant differences were found between males and females in any metric assessed (all\n                      <jats:italic>P<\/jats:italic>\n                      &gt; .05). Seven studies reported clinical outcomes after treatment of knee OCD lesions. One study determined males were more likely to have a successful nonoperative outcome than females (OR: 1.85, 95% CI: 1.00\u20103.40). Another study found males had a lower risk of developing symptomatic knee pain following operative or nonoperative treatment at a mean 14\u2010year follow\u2010up (HR: 0.24; 95% CI: 0.07\u20100.81). The remaining 5 studies reported statistically comparable clinical outcomes between males and females (all\n                      <jats:italic>P<\/jats:italic>\n                      &gt; .05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The present systematic review found mostly comparable clinical and functional outcomes between males and females following treatment of knee OCD lesions. Despite sex\u2010related differences in the prevalence of these lesions and limited evidence of differences in clinical outcomes, these data suggest that sex does not independently predict outcomes after treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>III, systematic review of Level II and III studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.arthro.2022.03.015","type":"journal-article","created":{"date-parts":[[2022,3,23]],"date-time":"2022-03-23T19:27:28Z","timestamp":1648063648000},"page":"2919-2929","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Males and Females Exhibit Comparable Outcomes Following Treatment of Osteochondritis Dissecans Lesions of the Knee: A Systematic Review"],"prefix":"10.1002","volume":"38","author":[{"given":"Bailey J.","family":"Ross","sequence":"first","affiliation":[{"name":"Tulane University School of Medicine New Orleans Louisiana U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina A.","family":"Hermanns","sequence":"additional","affiliation":[{"name":"University of Kansas School of Medicine Kansas City Kansas U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shin","family":"Xu","sequence":"additional","affiliation":[{"name":"University of Kansas Department of Orthopedics Kansas City Kansas U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jordan","family":"Baker","sequence":"additional","affiliation":[{"name":"University of Kansas School of Medicine Kansas City Kansas U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bryan","family":"Vopat","sequence":"additional","affiliation":[{"name":"University of Kansas Department of Orthopedics Kansas City Kansas U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cadence","family":"Miskimin","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Tulane University School of Medicine New Orleans Louisiana U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary K.","family":"Mulcahey","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Tulane University School of Medicine New Orleans Louisiana U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,3,22]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546518764676"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/1947603517715736"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otsr.2017.02.016"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/BPO.0000000000000839"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.csm.2017.02.005"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.98B6.36816"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.3928\/01477447-20210414-09"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1177\/1947603518786545"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/2325967116635515"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1186\/2046-4053-4-1"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200301000-00001"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.2307\/2529310"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546513496049"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/BPB.0000000000000617"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1177\/03635465010290050701"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1177\/2325967119886591"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546517699846"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.G.01103"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm8111934"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546519841378"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/7912975"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546513510390"},{"key":"e_1_2_5_24_2","article-title":"The demographics, epidemiology, and incidence of progression to surgery of osteochondritis dissecans of the knee in children and adolescents","volume":"1","author":"Kessler J.I.","year":"2013","journal-title":"Orthop J Sports Med"},{"key":"e_1_2_5_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2017.07.005"},{"key":"e_1_2_5_26_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546514562174"},{"key":"e_1_2_5_27_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002560050267"},{"key":"e_1_2_5_28_2","first-page":"231","article-title":"Osteochondritis dissecans: A multicenter study of the European pediatric orthopedic society","volume":"8","author":"Hefti F.","year":"1999","journal-title":"J\u00a0Pediatr Orthop B"},{"key":"e_1_2_5_29_2","doi-asserted-by":"publisher","DOI":"10.1177\/2325967117704644"},{"key":"e_1_2_5_30_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-020-06365-y"},{"key":"e_1_2_5_31_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546509332258"},{"key":"e_1_2_5_32_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.88B1.16796"},{"key":"e_1_2_5_33_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546513489262"},{"key":"e_1_2_5_34_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-012-2280-3"},{"key":"e_1_2_5_35_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200209000-00026"},{"key":"e_1_2_5_36_2","doi-asserted-by":"publisher","DOI":"10.1002\/jor.20977"}],"container-title":["Arthroscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749806322001645?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749806322001645?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/arthroscopyjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.arthro.2022.03.015","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/arthroscopyjournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1016\/j.arthro.2022.03.015","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/arthroscopyjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.arthro.2022.03.015","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T09:16:51Z","timestamp":1773566211000},"score":1,"resource":{"primary":{"URL":"https:\/\/arthroscopyjournals.onlinelibrary.wiley.com\/doi\/10.1016\/j.arthro.2022.03.015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,22]]},"references-count":35,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.1016\/j.arthro.2022.03.015"],"URL":"https:\/\/doi.org\/10.1016\/j.arthro.2022.03.015","archive":["Portico"],"relation":{},"ISSN":["0749-8063","1526-3231"],"issn-type":[{"value":"0749-8063","type":"print"},{"value":"1526-3231","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,22]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Males and Females Exhibit Comparable Outcomes Following Treatment of Osteochondritis Dissecans Lesions of the Knee: A Systematic Review","name":"articletitle","label":"Article Title"},{"value":"Arthroscopy: The Journal of Arthroscopic & Related Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arthro.2022.03.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 by the Arthroscopy Association of North America","name":"copyright","label":"Copyright"}]}}