{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T05:20:25Z","timestamp":1783488025725,"version":"3.55.0"},"reference-count":35,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T00:00:00Z","timestamp":1724112000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T00:00:00Z","timestamp":1724112000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T00:00:00Z","timestamp":1724112000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T00:00:00Z","timestamp":1724112000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T00:00:00Z","timestamp":1725408000000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009401","name":"Ludwig-Maximilians-Universitat Munchen Medizinische Fakultat","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009401","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","arthroscopyjournal.org","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Arthroscopy"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To examine how augmentation of a rotator cuff repair with inflamed versus noninflamed bursal tissue affects tendon\u2010to\u2010bone healing in a rat model of rotator cuff repair.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 136 Sprague\u2010Dawley rats were randomly assigned to an inflamed or noninflamed bursal tissue application group. After detachment, the supraspinatus tendon was reattached with bursal tissue sewn onto the tendon\u2010to\u2010bone interface. The specimens were analyzed biomechanically 6 and at 7 weeks and immunohistologically at 1 and at 7 weeks after surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Immunohistological results showed no significant difference in the percentage of collagen type II in the tendon\u2010to\u2010bone interface at 1 (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0= .87) and 7 weeks (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0= .42) when using autologous noninflamed bursal tissue in comparison with inflamed bursal tissue specimens. The inflamed bursa group also showed no significant difference in collagen I to III quotient (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0= .14) after surgery in comparison with noninflamed bursa groups after surgery. Biomechanical assessment showed that tendon stiffness (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0= .87 inflamed versus noninflammed (resp.)\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0= .1) and the tendon viscoelasticity (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0= .12 resp.\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0= .07) was the same after 6 and 7 weeks when we compared the inflamed bursa with the noninflamed bursa group. There was no significant difference (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0= .8 resp.\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0= .87) in load to failure between in both inflamed and noninflamed bursa groups after 6 and 7 weeks.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Autologous inflamed bursal tissue derived from the Achilles bursa and implanted to the tendon\u2010to\u2010bone interface after rotator cuff repair facilitates the same histologic and biomechanical healing response as using a noninflamed bursa interposition in rats.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Relevance<\/jats:title>\n                    <jats:p>During augmentation of a rotator cuff repair, it is irrelevant whether the bursa tissue is inflamed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.arthro.2024.07.036","type":"journal-article","created":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T17:29:05Z","timestamp":1724347745000},"page":"1316-1325","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Comparison of Biological Augmentation in Rotator Cuff Repair Using Inflamed Versus Noninflamed Bursal Tissue in Rats"],"prefix":"10.1002","volume":"41","author":[{"given":"Anja Z.","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Orthopedics and Trauma Surgery Musculoskeletal University Center Munich (MUM) University Hospital LMU Munich Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Ficklscherer","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Trauma Surgery Musculoskeletal University Center Munich (MUM) University Hospital LMU Munich Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas R.","family":"Niethammer","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Trauma Surgery Musculoskeletal University Center Munich (MUM) University Hospital LMU Munich Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Woiczinski","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Trauma Surgery Musculoskeletal University Center Munich (MUM) University Hospital LMU Munich Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Davies\u2010Knorr","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Trauma Surgery Musculoskeletal University Center Munich (MUM) University Hospital LMU Munich Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boris M.","family":"Holzapfel","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Trauma Surgery Musculoskeletal University Center Munich (MUM) University Hospital LMU Munich Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter E.","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Trauma Surgery Musculoskeletal University Center Munich (MUM) University Hospital LMU Munich Munich 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