{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T19:13:29Z","timestamp":1773602009861,"version":"3.50.1"},"reference-count":6,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T00:00:00Z","timestamp":1725494400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T00:00:00Z","timestamp":1725494400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T00:00:00Z","timestamp":1725494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T00:00:00Z","timestamp":1725494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","arthroscopyjournal.org","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Arthroscopy"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The search for the ideal pain management strategy after knee arthroscopy continues. For patients unable to receive regional anesthesia, peri\u2010articular or intra\u2010articular injections of local anesthetics with other medications offer a promising solution. Dexmedetomidine (a short\u2010term sedative analgesic marketed under the names Dexdor and Precedex), when added to local anesthetics, may offer an increase in the length of time between surgery and the need for a rescue analgesic agent. Whether the addition of dexmedetomidine results in lower pain scores or decreased opioid consumption remains to be proven. Systemic effects of dexmedetomidine, such as sedation and hypotension, appear less likely to occur with intra\u2010articular injections, suggesting a favorable safety profile. The effects of dexmedetomidine on chondrocytes, as well as the effects of combining medications in the intra\u2010articular environment, are less well understood and should be a focus of further research. Similarly, there is still a need to identify the best patients, best procedures, best combination of medications, and best doses to optimize our approach to post\u2010operative pain management via intra\u2010articular injection.<\/jats:p>","DOI":"10.1016\/j.arthro.2024.08.040","type":"journal-article","created":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T09:07:07Z","timestamp":1725613627000},"page":"1070-1071","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["<i>Editorial Commentary<\/i>\n                    : Addition of Dexmedetomidine to Local Analgesia for Knee Arthroscopy"],"prefix":"10.1002","volume":"41","author":[{"given":"Jeanne C.","family":"Patzkowski","sequence":"first","affiliation":[{"name":"San Antonio Texas U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael S.","family":"Patzkowski","sequence":"additional","affiliation":[{"name":"San Antonio Texas U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,9,5]]},"reference":[{"key":"e_1_2_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2024.06.043"},{"key":"e_1_2_3_3_2","doi-asserted-by":"publisher","DOI":"10.2147\/JPR.S398329"},{"key":"e_1_2_3_4_2","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.K.01333"},{"key":"e_1_2_3_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/anae.15641"},{"key":"e_1_2_3_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0000000000001220"},{"key":"e_1_2_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2023.01.029"}],"container-title":["Arthroscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749806324006443?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749806324006443?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/arthroscopyjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.arthro.2024.08.040","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/arthroscopyjournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1016\/j.arthro.2024.08.040","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/arthroscopyjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.arthro.2024.08.040","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T09:05:42Z","timestamp":1773565542000},"score":1,"resource":{"primary":{"URL":"https:\/\/arthroscopyjournals.onlinelibrary.wiley.com\/doi\/10.1016\/j.arthro.2024.08.040"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,5]]},"references-count":6,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1016\/j.arthro.2024.08.040"],"URL":"https:\/\/doi.org\/10.1016\/j.arthro.2024.08.040","archive":["Portico"],"relation":{},"ISSN":["0749-8063","1526-3231"],"issn-type":[{"value":"0749-8063","type":"print"},{"value":"1526-3231","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Editorial Commentary: Addition of Dexmedetomidine to Local Analgesia for Knee Arthroscopy","name":"articletitle","label":"Article Title"},{"value":"Arthroscopy: The Journal of Arthroscopic & Related Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arthro.2024.08.040","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.arthro.2024.06.043","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc. on behalf of the Arthroscopy Association of North America","name":"copyright","label":"Copyright"}]}}