{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T23:14:03Z","timestamp":1784848443313,"version":"3.55.0"},"reference-count":46,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T00:00:00Z","timestamp":1738195200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T00:00:00Z","timestamp":1738195200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T00:00:00Z","timestamp":1738195200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T00:00:00Z","timestamp":1738195200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["arthroscopyjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Arthroscopy"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate rates of achieving meaningful outcomes and clinical failure at 2 years after undergoing microfracture augmented with allograft cartilage with autologous platelet\u2010rich plasma and to identify predictors of conversion to total hip arthroplasty (THA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data from a prospective series of consecutive patients with Outerbridge grade 4 chondromalacia of the acetabulum or femoral head who underwent hip microfracture augmented with allograft cartilage between January 2017 and June 2022 were analyzed. Patient\u2010reported outcomes were collected preoperatively and at a minimum of 2 years postoperatively. The Hip Outcome Score\u2013Activities of Daily Living Subscale, Hip Outcome Score\u2013Sports\u2010Specific Subscale, modified Harris Hip Score, and Non\u2010arthritic Hip Score thresholds for achieving the minimal clinically important difference, patient acceptable symptomatic state, and substantial clinical benefit at 2 years after surgery were calculated. Logistic regression analysis was performed to identify any association between nonmodifiable variables and clinical failure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 108 hips (80.6% follow\u2010up) among 106 patients had 2\u2010year follow\u2010up and were included in the final analysis. The mean age and body mass index (BMI) were 37.9 \u00b1 10.1 years and 26.8 \u00b1 4.7, respectively, with a mean follow\u2010up time of 31.9 \u00b1 8.4 months (range, 24\u201053 months). There was a statistically significant improvement in all functional score averages over the 2\u2010year period (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .05). A total of 84.7%, 75.5%, and 70.4% of patients reached at least 1 threshold for achieving the minimal clinically important difference, patient acceptable symptomatic state, and substantial clinical benefit, respectively. There were 11 patients (10.2%) who underwent conversion to THA, with increased age, BMI, and preoperative pain duration increasing the likelihood of requiring THA (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .05 for all). Finally, chondromalacia size or chondromalacia index (e.g., Outerbridge grade \u00d7 surface area) was not associated with clinical failure or achievement of meaningful outcomes (\n                      <jats:italic>P<\/jats:italic>\n                      &gt; .05 for all).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Patients undergoing microfracture with allograft cartilage and autologous platelet\u2010rich plasma augmentation for acetabular or femoral head chondromalacia showed a statistically significant improvement in outcome scores and high rates of achieving meaningful outcomes at 2\u2010year follow\u2010up regardless of chondromalacia defect size. The rate of conversion to THA was 10.2%, with increased age, BMI, and preoperative pain duration increasing the likelihood of requiring THA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level IV, therapeutic study.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.arthro.2025.01.022","type":"journal-article","created":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T17:26:31Z","timestamp":1738257991000},"page":"2856","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Patients Undergoing Microfracture With Allograft Cartilage and Autologous Platelet\u2010Rich Plasma Augmentation for Chondromalacia in the Hip Achieving High Rates of Meaningful Outcomes at 2\u2010Year Follow\u2010Up"],"prefix":"10.1002","volume":"41","author":[{"given":"Edward C.","family":"Beck","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery Atrium Health Wake Forest Baptist Winston\u2010Salem North Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mina","family":"Entessari","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Atrium Health Wake Forest Baptist Winston\u2010Salem North Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avinesh","family":"Agarwalla","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Cedars\u2010Sinai Kerlan\u2010Jobe Institute Los Angeles California U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Mason","sequence":"additional","affiliation":[{"name":"College of Medicine Wake Forest University Winston\u2010Salem North Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffery D.","family":"St. Jeor","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Atrium Health Wake Forest Baptist Winston\u2010Salem North Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allston J.","family":"Stubbs","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Atrium Health Wake Forest Baptist Winston\u2010Salem North Carolina 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