{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T12:29:14Z","timestamp":1773664154447,"version":"3.50.1"},"reference-count":108,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2006,12,1]],"date-time":"2006-12-01T00:00:00Z","timestamp":1164931200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthropod Structure &amp; Development"],"published-print":{"date-parts":[[2006,12]]},"DOI":"10.1016\/j.asd.2006.09.002","type":"journal-article","created":{"date-parts":[[2006,12,13]],"date-time":"2006-12-13T00:55:04Z","timestamp":1165971304000},"page":"379-391","source":"Crossref","is-referenced-by-count":32,"title":["Pax6 and eye development in Arthropoda"],"prefix":"10.1016","volume":"35","author":[{"given":"Patrick","family":"Callaerts","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason","family":"Clements","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"Francis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Korneel","family":"Hens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.asd.2006.09.002_bib1","first-page":"55","article-title":"Postembryonic development of the visual system of the locust, Schistocerca gregaria","volume":"45","author":"Anderson","year":"1978","journal-title":"Journal of Embryology and experimental Morphology"},{"key":"10.1016\/j.asd.2006.09.002_bib2","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.ydbio.2005.04.034","article-title":"Functional analyses in the milkweed bug Oncopeltus fasciatus (Hemiptera) support a role for Wnt signaling in body segmentation but not appendage development","volume":"283","author":"Angelini","year":"2005","journal-title":"Developmental Biology"},{"key":"10.1016\/j.asd.2006.09.002_bib3","first-page":"563","article-title":"Evolution of eyes and photoreceptor cell types","volume":"47","author":"Arendt","year":"2003","journal-title":"International Journal of Developmental Biology"},{"key":"10.1016\/j.asd.2006.09.002_bib4","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1098\/rstb.2001.0971","article-title":"Reconstructing the eyes of Urbilateria","volume":"356","author":"Arendt","year":"2001","journal-title":"Philosophical Transactions of the Royal Society London B"},{"key":"10.1016\/j.asd.2006.09.002_bib5","doi-asserted-by":"crossref","first-page":"2673","DOI":"10.1242\/dev.122.9.2673","article-title":"In vivo requirement for the paired domain and homeodomain of the paired segmentation gene product","volume":"122","author":"Bertuccioli","year":"1996","journal-title":"Development"},{"key":"10.1016\/j.asd.2006.09.002_bib6","doi-asserted-by":"crossref","first-page":"5011","DOI":"10.1242\/dev.02082","article-title":"Restricted teashirt expression confers eye-specific responsiveness to Dpp and Wg signals during eye specification in Drosophila","volume":"132","author":"Bessa","year":"2005","journal-title":"Development"},{"key":"10.1016\/j.asd.2006.09.002_bib7","doi-asserted-by":"crossref","first-page":"2415","DOI":"10.1101\/gad.1009002","article-title":"Combinatorial control of Drosophila eye development by eyeless, homothorax, and teashirt","volume":"16","author":"Bessa","year":"2002","journal-title":"Genes and Development"},{"key":"10.1016\/j.asd.2006.09.002_bib8","series-title":"Crustaceans & Arthropod Relationships","first-page":"185","article-title":"Evolution of eye structure and arthropod phylogeny","author":"Bitsch","year":"2005"},{"key":"10.1016\/j.asd.2006.09.002_bib9","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/0092-8674(93)90115-7","article-title":"The eyes absent gene: genetic control of cell survival and differentiation in the developing Drosophila eye","volume":"72","author":"Bonini","year":"1993","journal-title":"Cell"},{"key":"10.1016\/j.asd.2006.09.002_bib10","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/0092-8674(95)90291-0","article-title":"Hairy and emc negatively regulate morphogenetic furrow progression in the Drosophila eye","volume":"80","author":"Brown","year":"1995","journal-title":"Cell"},{"key":"10.1016\/j.asd.2006.09.002_bib11","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1006\/dbio.1996.0267","article-title":"Hedgehog dependent patterning in the Drosophila eye can occur in the absence of Dpp signaling","volume":"179","author":"Brown","year":"1996","journal-title":"Developmental Biology"},{"key":"10.1016\/j.asd.2006.09.002_bib12","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1146\/annurev.neuro.20.1.483","article-title":"Pax-6 in development and evolution","volume":"20","author":"Callaerts","year":"1997","journal-title":"Annual Reviews of Neuroscience"},{"key":"10.1016\/j.asd.2006.09.002_bib13","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1073\/pnas.96.2.558","article-title":"Isolation and expression of a Pax-6 gene in the regenerating and intact Planarian Dugesia (G) tigrina","volume":"96","author":"Callaerts","year":"1999","journal-title":"Proceedings of the National Academy of Sciences U.S.A."},{"key":"10.1016\/j.asd.2006.09.002_bib14","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1002\/1097-4695(20010205)46:2<73::AID-NEU10>3.0.CO;2-N","article-title":"Drosophila Pax-6\/eyeless is essential for normal adult brain structure and function","volume":"46","author":"Callaerts","year":"2001","journal-title":"Journal of Neurobiology"},{"key":"10.1016\/j.asd.2006.09.002_bib15","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1007\/s004270050191","article-title":"Pax-6 origins\u2013implications from the structure of two coral pax genes","volume":"208","author":"Catmull","year":"1998","journal-title":"Development Genes and Evolution"},{"key":"10.1016\/j.asd.2006.09.002_bib16","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/S0092-8674(00)80481-X","article-title":"Dachshund and eyes absent proteins form a complex and function synergistically to induce ectopic eye development in Drosophila","volume":"91","author":"Chen","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.asd.2006.09.002_bib17","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1242\/dev.126.5.935","article-title":"Signaling by the TGF-beta homolog decapentaplegic functions reiteratively within the network of genes controlling retinal cell fate determination in Drosophila","volume":"126","author":"Chen","year":"1999","journal-title":"Development"},{"key":"10.1016\/j.asd.2006.09.002_bib18","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1016\/0896-6273(94)90308-5","article-title":"The Drosophila sine oculis locus encodes a homeodomain-containing protein required for the development of the entire visual system","volume":"12","author":"Cheyette","year":"1994","journal-title":"Neuron"},{"key":"10.1016\/j.asd.2006.09.002_bib19","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1038\/377052a0","article-title":"Patterning of the Caenorhabditis elegans head region by the Pax-6 family member vab-3","volume":"377","author":"Chisholm","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.asd.2006.09.002_bib20","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0092-8674(00)00124-0","article-title":"Novel signaling from the peripodial membrane is essential for eye disc patterning in Drosophila","volume":"103","author":"Cho","year":"2000","journal-title":"Cell"},{"key":"10.1016\/j.asd.2006.09.002_bib21","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1242\/dev.127.6.1325","article-title":"Morphogenetic furrow initiation and progression during eye development in Drosophila: the roles of decapentaplegic, hedgehog and eyes absent","volume":"127","author":"Curtiss","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.asd.2006.09.002_bib22","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S1097-2765(00)80457-8","article-title":"twin of eyeless, a second Pax-6 gene of Drosophila, acts upstream of eyeless in the control of eye development","volume":"3","author":"Czerny","year":"1999","journal-title":"Molecular Cell"},{"key":"10.1016\/j.asd.2006.09.002_bib23","doi-asserted-by":"crossref","first-page":"3435","DOI":"10.1242\/dev.128.18.3435","article-title":"Early embryo patterning in the grasshopper, Schistocerca gregaria: wingless, decapentaplegic and caudal expression","volume":"128","author":"Dearden","year":"2001","journal-title":"Development"},{"key":"10.1016\/j.asd.2006.09.002_bib24","first-page":"85","article-title":"Are the insects terrestrial crustaceans? A discussion of some new facts and arguments and the proposal of the proper name \u201cTetraconata\u201d for the monophyletic unit Crustacea+Hexapoda","volume":"37","author":"Dohle","year":"2001","journal-title":"Annales de la Soci\u00e9t\u00e9 Entomologique de France (NS)"},{"key":"10.1016\/j.asd.2006.09.002_bib25","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/ng1281","article-title":"Growth and specification of the eye are controlled independently by Eyegone and Eyeless in Drosophila melanogaster","volume":"36","author":"Dominguez","year":"2004","journal-title":"Nature Genetics"},{"key":"10.1016\/j.asd.2006.09.002_bib26","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/s00427-004-0465-6","article-title":"Comparative analysis of wingless patterning in the embryonic grasshopper eye","volume":"215","author":"Dong","year":"2005","journal-title":"Development Genes and Evolution"},{"key":"10.1016\/j.asd.2006.09.002_bib27","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1007\/s00427-002-0215-6","article-title":"Analysis of the expression pattern of Mysidium columbiae wingless provides evidence for conserved mesodermal and retinal patterning processes among insects and crustaceans","volume":"212","author":"Duman-Scheel","year":"2002","journal-title":"Development Genes and Evolution"},{"key":"10.1016\/j.asd.2006.09.002_bib108","doi-asserted-by":"crossref","first-page":"2292","DOI":"10.1093\/emboj\/19.10.2292","article-title":"Transcruptional repression by Pox5 (BSAP) through interaction with corepressors of the Groucho Pamchy","volume":"19","author":"Eberhard","year":"2000","journal-title":"EMBO Journal"},{"key":"10.1016\/j.asd.2006.09.002_bib28","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1101\/gad.8.17.2022","article-title":"Two independent and interactive DNA-binding subdomains of the Pax6 paired domain are regulated by alternative splicing","volume":"8","author":"Epstein","year":"1994","journal-title":"Genes and Development"},{"key":"10.1016\/j.asd.2006.09.002_bib29","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/S0959-4388(00)00114-8","article-title":"Evolution of eyes","volume":"10","author":"Fernald","year":"2000","journal-title":"Current Opinion in Neurobiology"},{"key":"10.1016\/j.asd.2006.09.002_bib30","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1242\/dev.129.6.1295","article-title":"R8 development in the Drosophila eye: a paradigm for neural selection and differentiation","volume":"129","author":"Frankfort","year":"2002","journal-title":"Development"},{"key":"10.1016\/j.asd.2006.09.002_bib31","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1093\/icb\/43.4.508","article-title":"Evolution of insect eye development: first insights from fruit fly, grasshopper and flour beetle","volume":"43","author":"Friedrich","year":"2003","journal-title":"Integrative and Comparative Biology"},{"key":"10.1016\/j.asd.2006.09.002_bib32","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1002\/(SICI)1097-010X(20000415)288:1<39::AID-JEZ5>3.0.CO;2-T","article-title":"Divergent decapentaplegic expression patterns in compound eye development and the evolution of insect metamorphosis","volume":"288","author":"Friedrich","year":"2000","journal-title":"Journal of Experimental Zoology"},{"key":"10.1016\/j.asd.2006.09.002_bib33","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1007\/s004270050039","article-title":"The early stages of ommatidial development in the flour beetle Tribolium castaneum (Coleoptera; Tenebrionidae)","volume":"206","author":"Friedrich","year":"1996","journal-title":"Development Genes and Evolution"},{"key":"10.1016\/j.asd.2006.09.002_bib34","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1038\/nature717","article-title":"Evolution of a transcriptional repression domain in an insect Hox protein","volume":"415","author":"Galant","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.asd.2006.09.002_bib35","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1002\/jez.1401700106","article-title":"Cell lineage of the imaginal discs in Drosophila gynandromorphs","volume":"170","author":"Garcia-Bellido","year":"1969","journal-title":"Journal of Experimental Zoology"},{"key":"10.1016\/j.asd.2006.09.002_bib36","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/BF00576800","article-title":"Developmental capacities of immature eye-antennal imaginal discs of Drosophila melanogaster","volume":"176","author":"Gateff","year":"1975","journal-title":"Wilhelm Roux Archives for Developmental Biology"},{"key":"10.1016\/j.asd.2006.09.002_bib37","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/S0168-9525(99)01776-X","article-title":"Pax 6: mastering eye morphogenesis and eye evolution","volume":"15","author":"Gehring","year":"1999","journal-title":"Trends in Genetics"},{"key":"10.1016\/j.asd.2006.09.002_bib38","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1111\/j.1096-0031.2000.tb00353.x","article-title":"A review of arthropod phylogeny: new data based on ribosomal DNA sequences and direct character optimization","volume":"16","author":"Giribet","year":"2000","journal-title":"Cladistics"},{"key":"10.1016\/j.asd.2006.09.002_bib39","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0925-4773(00)00286-0","article-title":"Characterization and expression analysis of an ancestor-type Pax gene in the hydrozoan jellyfish Podocoryne carnea","volume":"94","author":"Groger","year":"2000","journal-title":"Mechanisms of Development"},{"key":"10.1016\/j.asd.2006.09.002_bib40","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1007\/s004410051146","article-title":"Morphogenesis and pattern formation in the retina of the crayfish Procambarus clarkii","volume":"293","author":"Hafner","year":"1998","journal-title":"Cell and Tissue Research"},{"key":"10.1016\/j.asd.2006.09.002_bib41","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s004410100413","article-title":"Retinal development in the lobster Homarus americanus. Comparison with compound eyes of insects and other crustaceans","volume":"305","author":"Hafner","year":"2001","journal-title":"Cell and Tissue Research"},{"key":"10.1016\/j.asd.2006.09.002_bib42","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1126\/science.7892602","article-title":"Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila","volume":"267","author":"Halder","year":"1995","journal-title":"Science"},{"key":"10.1016\/j.asd.2006.09.002_bib43","doi-asserted-by":"crossref","first-page":"2181","DOI":"10.1242\/dev.125.12.2181","article-title":"Eyeless initiates the expression of both sine oculis and eyes absent during Drosophila compound eye development","volume":"125","author":"Halder","year":"1998","journal-title":"Development"},{"key":"10.1016\/j.asd.2006.09.002_bib44","first-page":"189","article-title":"Maturation of the compound eyes and eyestalk ganglia during larval development of brachyuran crustaceans Hyas araneus. (Decapoda, Majidae) and Carcinus maenas L. (Decapoda, Portunidae)","volume":"99","author":"Harzsch","year":"1995","journal-title":"Zoology"},{"key":"10.1016\/j.asd.2006.09.002_bib45","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s004270000113","article-title":"Neurogenesis in the developing visual system of the branchiopod crustacean Triops longicaudatus (LeConte, 1846): corresponding patterns of compound-eye formation in Crustacea and Insecta?","volume":"211","author":"Harzsch","year":"2001","journal-title":"Development Genes and Evolution"},{"key":"10.1016\/j.asd.2006.09.002_bib46","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1038\/354522a0","article-title":"Mouse small eye results from mutations in a paired-like homeobox-containing gene","volume":"354","author":"Hill","year":"1991","journal-title":"Nature"},{"key":"10.1016\/j.asd.2006.09.002_bib47","doi-asserted-by":"crossref","first-page":"2939","DOI":"10.1242\/dev.00522","article-title":"Two Pax genes, eye gone and eyeless, act cooperatively in promoting Drosophila eye development","volume":"130","author":"Jang","year":"2003","journal-title":"Development"},{"key":"10.1016\/j.asd.2006.09.002_bib48","doi-asserted-by":"crossref","first-page":"2639","DOI":"10.1242\/dev.122.9.2639","article-title":"Cooperative interactions between paired domain and homeodomain","volume":"122","author":"Jun","year":"1996","journal-title":"Development"},{"key":"10.1016\/j.asd.2006.09.002_bib49","doi-asserted-by":"crossref","first-page":"13720","DOI":"10.1073\/pnas.95.23.13720","article-title":"Lune\/eye gone, a Pax-like protein, uses a partial paired domain and a homeodomain for DNA recognition","volume":"95","author":"Jun","year":"1998","journal-title":"Proceedings of the National Academy of Sciences of the U S A."},{"key":"10.1016\/j.asd.2006.09.002_bib50","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S1534-5807(03)00243-0","article-title":"Coordinating proliferation and tissue specification to promote regional identity in the Drosophila head","volume":"5","author":"Kenyon","year":"2003","journal-title":"Developmental Cell"},{"key":"10.1016\/j.asd.2006.09.002_bib51","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/S0969-2126(02)00769-4","article-title":"Structure of the retinal determination protein dachshund reveals a DNA binding motif","volume":"10","author":"Kim","year":"2002","journal-title":"Structure"},{"key":"10.1016\/j.asd.2006.09.002_bib52","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/S1534-5807(03)00325-3","article-title":"Role of Pax genes in eye evolution: a cnidarian PaxB\u00a0gene uniting Pax2 and Pax6 functions","volume":"5","author":"Kozmik","year":"2003","journal-title":"Developmental Cell"},{"key":"10.1016\/j.asd.2006.09.002_bib53","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1242\/dev.129.4.1015","article-title":"Headless flies produced by mutations in the paralogous Pax6 genes eyeless and twin of eyeless","volume":"129","author":"Kronhamn","year":"2002","journal-title":"Development"},{"key":"10.1016\/j.asd.2006.09.002_bib54","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1007\/s004270100177","article-title":"Expression of evolutionarily conserved eye specification genes during Drosophila embryogenesis","volume":"211","author":"Kumar","year":"2001","journal-title":"Development Genes and Evolution"},{"key":"10.1016\/j.asd.2006.09.002_bib55","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/S0092-8674(01)00265-3","article-title":"EGF receptor and Notch signalling act upstream of Eyeless\/Pax6 to control eye specification","volume":"104","author":"Kumar","year":"2001","journal-title":"Cell"},{"key":"10.1016\/j.asd.2006.09.002_bib56","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1093\/bib\/5.2.150","article-title":"MEGA 3: integrated software for molecular evolutionary genetics analysis and sequence alignment","volume":"5","author":"Kumar","year":"2004","journal-title":"Briefings in Bioinformatics"},{"key":"10.1016\/j.asd.2006.09.002_bib57","doi-asserted-by":"crossref","first-page":"2140","DOI":"10.1073\/pnas.040564497","article-title":"Genetic control of development of the mushroom bodies, the associative learning centers in the Drosophila brain, by the eyeless, twin of eyeless, and Dachshund genes","volume":"97","author":"Kurusu","year":"2000","journal-title":"Proceedings of the National Academy of Sciences U S A."},{"key":"10.1016\/j.asd.2006.09.002_bib58","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1146\/annurev.ne.15.030192.000245","article-title":"The evolution of eyes","volume":"15","author":"Land","year":"1992","journal-title":"Annual Reviews of Neurosciences"},{"key":"10.1016\/j.asd.2006.09.002_bib59","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1038\/nature02083","article-title":"Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis","volume":"426","author":"Li","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.asd.2006.09.002_bib60","unstructured":"Loosli, F., 1995. Cloning of a Lineus sanguineus gene homologous to Pax-6. Ph.D. thesis. Biozentrum, Basel, Switzerland."},{"key":"10.1016\/j.asd.2006.09.002_bib61","doi-asserted-by":"crossref","first-page":"3473","DOI":"10.1242\/dev.120.12.3473","article-title":"dachshund encodes a nuclear protein required for normal eye and leg development in Drosophila","volume":"120","author":"Mardon","year":"1994","journal-title":"Development"},{"key":"10.1016\/j.asd.2006.09.002_bib62","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0092-8674(01)00295-1","article-title":"Pax6 is required for the multipotent state of retinal progenitor cells","volume":"105","author":"Marquardt","year":"2001","journal-title":"Cell"},{"key":"10.1016\/j.asd.2006.09.002_bib63","series-title":"Developmental Neurobiology of Arthropods","first-page":"51","article-title":"Development of the compound eye and optic\u00a0lobes of insects","author":"Meinertzhagen","year":"1973"},{"key":"10.1016\/j.asd.2006.09.002_bib64","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1007\/s001140050442","article-title":"Compound eye evolution: highly conserved retinula and cone cell patterns indicate a common origin of the insect and crustacean ommatidium","volume":"84","author":"Melzer","year":"1997","journal-title":"Naturwissenschaften"},{"key":"10.1016\/j.asd.2006.09.002_bib65","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1007\/s001140050727","article-title":"Walking on insect paths? Early ommatidial development in the compound eye of the ancestral crustacean, Triops cancriformis","volume":"87","author":"Melzer","year":"2000","journal-title":"Naturwissenschaften"},{"key":"10.1016\/j.asd.2006.09.002_bib66","doi-asserted-by":"crossref","first-page":"4024","DOI":"10.1073\/pnas.0630561100","article-title":"Analysis of the eye developmental pathway in Drosophila using DNA microarrays","volume":"100","author":"Michaut","year":"2003","journal-title":"Proceedings of the National Academy of Sciences U.S.A."},{"key":"10.1016\/j.asd.2006.09.002_bib67","doi-asserted-by":"crossref","first-page":"4475","DOI":"10.1073\/pnas.97.9.4475","article-title":"Pax gene diversity in the basal cnidarian Acropora millepora (Cnidaria, Anthozoa): implications for the evolution of the Pax gene family","volume":"97","author":"Miller","year":"2000","journal-title":"Proceedings of the National Academy of Sciences U S A."},{"key":"10.1016\/j.asd.2006.09.002_bib68","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1038\/367460a0","article-title":"Conservation of wingless patterning functions in the short-germ embryos of Tribolium castaneum","volume":"367","author":"Nagy","year":"1994","journal-title":"Nature"},{"key":"10.1016\/j.asd.2006.09.002_bib69","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.1242\/dev.126.10.2253","article-title":"Direct regulatory interaction of the eyeless protein with an eye-specific enhancer in the sine oculis gene during eye induction in Drosophila","volume":"126","author":"Niimi","year":"1999","journal-title":"Development"},{"key":"10.1016\/j.asd.2006.09.002_bib70","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0960-9822(02)00417-7","article-title":"Eye ancestry: old genes for new eyes","volume":"6","author":"Nilson","year":"1996","journal-title":"Current Biology"},{"key":"10.1016\/j.asd.2006.09.002_bib71","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0925-4773(98)00156-7","article-title":"Zebrafish contains two pax6 genes involved in eye development","volume":"77","author":"Nornes","year":"1998","journal-title":"Mechanisms of Development"},{"key":"10.1016\/j.asd.2006.09.002_bib72","doi-asserted-by":"crossref","first-page":"3475","DOI":"10.1242\/dev.127.16.3475","article-title":"Early development of the Drosophila mushroom body: the roles of eyeless and dachshund","volume":"127","author":"Noveen","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.asd.2006.09.002_bib73","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1101\/gr.4673006","article-title":"Genome-wide identification of direct targets of the Drosophila retinal determination protein Eyeless","volume":"16","author":"Ostrin","year":"2006","journal-title":"Genome Research"},{"key":"10.1016\/j.asd.2006.09.002_bib74","series-title":"Drosophila Eye Development","first-page":"5","article-title":"Retinal specification and determination in Drosophila","author":"Pappu","year":"2002"},{"key":"10.1016\/j.asd.2006.09.002_bib75","doi-asserted-by":"crossref","first-page":"3053","DOI":"10.1242\/dev.00534","article-title":"Mechanism of hedgehog signaling during Drosophila eye development","volume":"130","author":"Pappu","year":"2003","journal-title":"Development"},{"key":"10.1016\/j.asd.2006.09.002_bib76","doi-asserted-by":"crossref","first-page":"2895","DOI":"10.1242\/dev.01869","article-title":"Dual regulation and redundant function of two eye-specific enhancers of the Drosophila retinal determination gene dachshund","volume":"132","author":"Pappu","year":"2005","journal-title":"Development"},{"key":"10.1016\/j.asd.2006.09.002_bib77","doi-asserted-by":"crossref","first-page":"2771","DOI":"10.1242\/dev.01841","article-title":"Identification of functional sine oculis motifs in the autoregulatory element of its own gene, in the eyeless enhancer and in the signalling gene hedgehog","volume":"132","author":"Pauli","year":"2005","journal-title":"Development"},{"key":"10.1016\/j.asd.2006.09.002_bib78","series-title":"Arthropod Phylogeny","first-page":"299","article-title":"Eye structure and the monophyly of the Arthropoda","author":"Paulus","year":"1979"},{"key":"10.1016\/j.asd.2006.09.002_bib79","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1046\/j.1439-0469.2000.383152.x","article-title":"Phylogeny of the Myriapoda \u2013 Crustacea \u2013 Insecta: a new attempt using photoreceptor structure","volume":"38","author":"Paulus","year":"2000","journal-title":"Journal of Zoological Systematics and Evolutionary Research"},{"key":"10.1016\/j.asd.2006.09.002_bib80","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/S0092-8674(00)80480-8","article-title":"The eye-specification proteins So and Eya form a complex and\u00a0regulate multiple steps in Drosophila eye development","volume":"91","author":"Pignoni","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.asd.2006.09.002_bib81","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.zool.2004.11.003","article-title":"Duplicated Pax6 genes in Glomeris marginata (Myriapoda: Diplopoda), an arthropod with simple lateral eyes","volume":"108","author":"Prpic","year":"2005","journal-title":"Zoology"},{"key":"10.1016\/j.asd.2006.09.002_bib82","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1242\/dev.129.3.625","article-title":"Differential interactions of eyeless and twin of eyeless with the sine oculis enhancer","volume":"129","author":"Punzo","year":"2002","journal-title":"Development"},{"key":"10.1016\/j.asd.2006.09.002_bib83","doi-asserted-by":"crossref","first-page":"3943","DOI":"10.1242\/dev.01278","article-title":"Functional divergence between eyeless and twin of eyeless in Drosophila melanogaster","volume":"131","author":"Punzo","year":"2004","journal-title":"Development"},{"key":"10.1016\/j.asd.2006.09.002_bib84","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1126\/science.7914031","article-title":"Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans","volume":"265","author":"Quiring","year":"1994","journal-title":"Science"},{"key":"10.1016\/j.asd.2006.09.002_bib85","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1038\/nature02093","article-title":"Eyes absent represents a class of protein tyrosine phosphatases","volume":"426","author":"Rayapureddi","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.asd.2006.09.002_bib86","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1002\/bies.20055","article-title":"Growth and specification: fly Pax6 homologs eyegone and eyeless have distinct functions","volume":"26","author":"Rodrigues","year":"2004","journal-title":"BioEssays"},{"key":"10.1016\/j.asd.2006.09.002_bib87","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1038\/nature716","article-title":"Hox protein mutation and macroevolution of the insect body plan","volume":"415","author":"Ronshaugen","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.asd.2006.09.002_bib88","doi-asserted-by":"crossref","first-page":"4793","DOI":"10.1242\/dev.124.23.4793","article-title":"Establishing primordia in the Drosophila eye-antennal imaginal disc: the roles of decapentaplegic, wingless and hedgehog","volume":"124","author":"Royet","year":"1997","journal-title":"Development"},{"key":"10.1016\/j.asd.2006.09.002_bib89","first-page":"207","article-title":"On the evolution of photoreceptors and eyes","volume":"10","author":"Salvini-Plawen","year":"1977","journal-title":"Evolutionary Biology"},{"key":"10.1016\/j.asd.2006.09.002_bib90","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1242\/dev.127.9.1879","article-title":"The Drosophila homeobox gene optix is capable of inducing ectopic eyes by an eyeless-independent mechanism","volume":"127","author":"Seimiya","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.asd.2006.09.002_bib91","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1093\/genetics\/138.4.1137","article-title":"Sine oculis is a homeobox gene required for Drosophila visual system development","volume":"138","author":"Serikaku","year":"1994","journal-title":"Genetics"},{"key":"10.1016\/j.asd.2006.09.002_bib92","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1242\/dev.01539","article-title":"Signaling circuitries in development: insights from the retinal determination gene network","volume":"132","author":"Silver","year":"2005","journal-title":"Development"},{"key":"10.1016\/j.asd.2006.09.002_bib93","doi-asserted-by":"crossref","first-page":"21531","DOI":"10.1074\/jbc.273.34.21531","article-title":"Truncation mutations in the transactivation region of PAX6 result in dominant-negative mutants","volume":"273","author":"Singh","year":"1998","journal-title":"The Journal of Biological Chemistry"},{"key":"10.1016\/j.asd.2006.09.002_bib94","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1093\/hmg\/10.9.911","article-title":"Missense mutation at the C-terminus of PAX6 negatively modulates homeodomain function","volume":"10","author":"Singh","year":"2001","journal-title":"Human Molecular Genetics"},{"key":"10.1016\/j.asd.2006.09.002_bib95","doi-asserted-by":"crossref","first-page":"5156","DOI":"10.1073\/pnas.94.10.5156","article-title":"Evolution of paired domains: isolation and sequencing of jellyfish and hydra Pax genes related to Pax-5 and Pax-6","volume":"94","author":"Sun","year":"1997","journal-title":"Proceedings of the National Academy of Sciences U S A."},{"key":"10.1016\/j.asd.2006.09.002_bib96","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1093\/oxfordjournals.molbev.a003731","article-title":"Isolation of Cladonema Pax-B genes and studies of the DNA-binding properties of cnidarian Pax paired domains","volume":"18","author":"Sun","year":"2001","journal-title":"Molecular Biology and Evolution"},{"key":"10.1016\/j.asd.2006.09.002_bib97","doi-asserted-by":"crossref","first-page":"7210","DOI":"10.1074\/jbc.273.13.7210","article-title":"Dissection of the transactivation function of the transcription factor encoded by the eye developmental gene PAX6","volume":"273","author":"Tang","year":"1998","journal-title":"The Journal of Biological Chemistry"},{"key":"10.1016\/j.asd.2006.09.002_bib98","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/0092-8674(91)90284-6","article-title":"Positional cloning and characterization of a paired box- and homeobox-containin gene from the Aniridia region","volume":"67","author":"Ton","year":"1991","journal-title":"Cell"},{"key":"10.1016\/j.asd.2006.09.002_bib99","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1038\/nature02097","article-title":"The transcription factor Eyes absent is a protein tyrosine phosphatase","volume":"426","author":"Tootle","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.asd.2006.09.002_bib100","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0070-2153(08)60454-8","article-title":"Eye development in Drosophila: formation of the eye field and control of differentiation","volume":"39","author":"Treisman","year":"1998","journal-title":"Current Topics in Developmental Biology"},{"key":"10.1016\/j.asd.2006.09.002_bib101","series-title":"Comprehensive Insect\u00a0Physiology and Pharmacology","first-page":"171","article-title":"The eye: development, structure and neural connections","author":"Trujillo-Cen\u00f3z","year":"1985"},{"key":"10.1016\/j.asd.2006.09.002_bib102","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1242\/dev.113.4.1435","article-title":"Pax-6, a murine paired box gene, is expressed in the developing CNS","volume":"113","author":"Walther","year":"1991","journal-title":"Development"},{"key":"10.1016\/j.asd.2006.09.002_bib103","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0012-1606(76)90150-0","article-title":"Clonal analysis of primordial disc cells in the early embryo of Drosophila melanogaster","volume":"50","author":"Wieschaus","year":"1976","journal-title":"Developmental Biology"},{"key":"10.1016\/j.asd.2006.09.002_bib104","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/BF00848883","article-title":"Gynandromorph analysis of the thoracic disc primordia in Drosophila melanogaster","volume":"180","author":"Wieschaus","year":"1976","journal-title":"Wilhelm Roux's Archives of Developmental Biology"},{"key":"10.1016\/j.asd.2006.09.002_bib105","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/0092-8674(95)90468-9","article-title":"High resolution crystal structure of a paired (Pax) class cooperative homeodomain dimer on DNA","volume":"82","author":"Wilson","year":"1995","journal-title":"Cell"},{"key":"10.1016\/j.asd.2006.09.002_bib106","series-title":"The Development of Drosophila melanogaster","first-page":"1277","article-title":"Pattern formation in the Drosophila retina","author":"Wolff","year":"1993"},{"key":"10.1016\/j.asd.2006.09.002_bib107","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1101\/gad.13.10.1263","article-title":"Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding","volume":"13","author":"Xu","year":"1999","journal-title":"Genes and Development"}],"container-title":["Arthropod Structure &amp; Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1467803906000648?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1467803906000648?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,8,5]],"date-time":"2021-08-05T22:14:51Z","timestamp":1628201691000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1467803906000648"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,12]]},"references-count":108,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006,12]]}},"alternative-id":["S1467803906000648"],"URL":"https:\/\/doi.org\/10.1016\/j.asd.2006.09.002","relation":{},"ISSN":["1467-8039"],"issn-type":[{"value":"1467-8039","type":"print"}],"subject":[],"published":{"date-parts":[[2006,12]]}}}