{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T10:23:48Z","timestamp":1776162228385,"version":"3.50.1"},"reference-count":48,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,1,26]],"date-time":"2016-01-26T00:00:00Z","timestamp":1453766400000},"content-version":"vor","delay-in-days":755,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Asian Journal of Surgery"],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.1016\/j.asjsur.2013.07.008","type":"journal-article","created":{"date-parts":[[2013,8,23]],"date-time":"2013-08-23T21:45:28Z","timestamp":1377294328000},"page":"35-45","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Anastomotic stability and wound healing of colorectal anastomoses sealed and sutured with a collagen fleece in a rat peritonitis model"],"prefix":"10.1016","volume":"37","author":[{"given":"Christoph","family":"Holmer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christiane","family":"Praechter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"Mecklenburg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"Heimesaat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hayo","family":"Rieger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uwe","family":"Pohlen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.asjsur.2013.07.008_bib1","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1159\/000008593","article-title":"Healing of colonic anastomoses after immediate and delayed administration of 5-fluorouracil plus folinic acid","volume":"30","author":"Kanellos","year":"1998","journal-title":"Eur Surg Res."},{"key":"10.1016\/j.asjsur.2013.07.008_bib2","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1002\/bjs.1800780117","article-title":"Effect of fibrin sealant on the healing colonic anastomosis in the rat","volume":"78","author":"van der Ham","year":"1991","journal-title":"Br J Surg."},{"key":"10.1016\/j.asjsur.2013.07.008_bib3","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1002\/bjs.1800790617","article-title":"Effect of antibiotics in fibrin sealant on healing colonic anastomoses in the rat","volume":"79","author":"van der Ham","year":"1992","journal-title":"Br J Surg."},{"key":"10.1016\/j.asjsur.2013.07.008_bib4","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.ejcts.2006.11.033","article-title":"Efficiency of fleece-bound sealing (TachoSil\u00ae) of air leaks in lung surgery: a prospective randomised trial","volume":"31","author":"Anegg","year":"2007","journal-title":"Eur J Cardiothorac Surg."},{"key":"10.1016\/j.asjsur.2013.07.008_bib5","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1007\/s00423-010-0703-5","article-title":"The effect of sealing with a fixed combination of collagen matrix-bound coagulation factors on the healing of colonic anastomoses in experimental high-risk mice models","volume":"395","author":"Pantelis","year":"2010","journal-title":"Langenbecks Arch Surg"},{"key":"10.1016\/j.asjsur.2013.07.008_bib6","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1016\/j.eururo.2007.04.027","article-title":"Efficacy and safety of TachoSil\u00ae as haemostatic treatment versus standard suturing in kidney tumour resection: a randomised prospective study","volume":"52","author":"Siemer","year":"2007","journal-title":"Eur Urol."},{"key":"10.1016\/j.asjsur.2013.07.008_bib7","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1517\/14712590903029172","article-title":"Efficacy of TachoSil\u00ae a fibrin-based haemostat in different fields of surgery\u2014a systematic review","volume":"9","author":"Rickenbacher","year":"2009","journal-title":"Expert Opin Biol Ther."},{"key":"10.1016\/j.asjsur.2013.07.008_bib8","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1007\/s00423-005-0543-x","article-title":"Effectiveness of a new carrier-bound fibrin sealant versus argon beamer as haemostatic agent during liver resection: a randomised prospective trial","volume":"390","author":"Frilling","year":"2005","journal-title":"Langenbecks Arch Surg"},{"key":"10.1016\/j.asjsur.2013.07.008_bib9","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.ejcts.2003.11.018","article-title":"Efficacy and safety of topical application of human fibrinogen\/thrombin-coated collagen patch (TachoComb) for treatment of air leakage after standard lobectomy","volume":"25","author":"Lang","year":"2004","journal-title":"Eur J Cardiothorac Surg."},{"key":"10.1016\/j.asjsur.2013.07.008_bib10","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/j.ejcts.2009.04.057","article-title":"TachoSil\u00ae surgical patch versus conventional haemostatic fleece material for control of bleeding in cardiovascular surgery: a randomised controlled trial","volume":"36","author":"Maisano","year":"2009","journal-title":"Eur J Cardiothorac Surg."},{"key":"10.1016\/j.asjsur.2013.07.008_bib11","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1001\/archsurg.2010.62","article-title":"A prospective study of the efficacy of clinical application of a new carrier-bound fibrin sealant after liver resection","volume":"145","author":"Briceno","year":"2010","journal-title":"Arch Surg."},{"key":"10.1016\/j.asjsur.2013.07.008_bib12","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.surg.2010.02.008","article-title":"Hemostatic efficacy of TachoSil\u00ae in liver resection compared with argon beam coagulator treatment: an open, randomized, prospective, multicenter, parallel-group trial","volume":"149","author":"Fischer","year":"2010","journal-title":"Surgery."},{"key":"10.1016\/j.asjsur.2013.07.008_bib13","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.ejcts.2010.03.061","article-title":"Efficacy and safety of TachoSil\u00ae((R)) versus standard treatment of air leakage after pulmonary lobectomy","volume":"38","author":"Marta","year":"2010","journal-title":"Eur J Cardiothorac Surg."},{"key":"10.1016\/j.asjsur.2013.07.008_bib14","first-page":"441","article-title":"Suture technique and early breaking strength of intestinal anastomoses and laparotomy wounds","volume":"151","author":"Hogstrom","year":"1985","journal-title":"Acta Chir Scand."},{"key":"10.1016\/j.asjsur.2013.07.008_bib15","series-title":"7th World Congress on Trauma, Shock, Inflammation and Sepsis","first-page":"125","article-title":"Bursting pressure, vascular integrity and collagen content of sutured and glued colorectal anastomoses in the rat model","author":"Rieger","year":"2007"},{"key":"10.1016\/j.asjsur.2013.07.008_bib16","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1007\/s10151-006-0285-y","article-title":"Does a fibrin\u2013collagen patch support early anastomotic healing in the colon? An experimental study","volume":"10","author":"Ozel","year":"2006","journal-title":"Tech Coloproctol."},{"key":"10.1016\/j.asjsur.2013.07.008_bib17","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1080\/08941930802713001","article-title":"Suture-free small bowel anastomoses using collagen fleece covered with fibrin glue in pigs","volume":"22","author":"Stumpf","year":"2009","journal-title":"J Invest Surg."},{"key":"10.1016\/j.asjsur.2013.07.008_bib18","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1080\/08941930701772173","article-title":"Sealing of gastrointestinal anastomoses with a fibrin glue-coated collagen patch: a safety study","volume":"20","author":"Nordentoft","year":"2007","journal-title":"J Invest Surg."},{"key":"10.1016\/j.asjsur.2013.07.008_bib19","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/S0002-9610(99)80082-8","article-title":"Intra-abdominal sepsis impairs colonic reparative collagen synthesis","volume":"171","author":"Ahrendt","year":"1996","journal-title":"Am J Surg."},{"key":"10.1016\/j.asjsur.2013.07.008_bib20","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1080\/110241500447137","article-title":"Effect of gentamicin-containing sponges on the healing of colonic anastomoses in a rat model of peritonitis","volume":"166","author":"Vaneerdeweg","year":"2000","journal-title":"Eur J Surg."},{"key":"10.1016\/j.asjsur.2013.07.008_bib21","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1046\/j.1365-2168.2000.01506.x","article-title":"van GH. Hyaluronic acid-based agents do not affect anastomotic strength in the rat colon, in either the presence or absence of bacterial peritonitis","volume":"87","author":"Reijnen","year":"2000","journal-title":"Br J Surg."},{"issue":"Suppl. 3","key":"10.1016\/j.asjsur.2013.07.008_bib22","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1159\/000088479","article-title":"VEGF as a therapeutic target in cancer","volume":"69","author":"Ferrara","year":"2005","journal-title":"Oncology"},{"key":"10.1016\/j.asjsur.2013.07.008_bib23","first-page":"1","article-title":"Healing of experimental colon anastomosis","volume":"566","author":"Brasken","year":"1991","journal-title":"Eur J Surg Suppl."},{"key":"10.1016\/j.asjsur.2013.07.008_bib24","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1007\/s00423-001-0255-9","article-title":"Collagen distribution and expression of matrix metalloproteinases 1 and 13 in patients with anastomotic leakage after large-bowel surgery","volume":"386","author":"Stumpf","year":"2002","journal-title":"Langenbecks Arch Surg."},{"key":"10.1016\/j.asjsur.2013.07.008_bib25","first-page":"925","article-title":"Granulocyte colony-stimulating factor prophylaxis before operation protects against lethal consequences of postoperative peritonitis","volume":"116","author":"Lorenz","year":"1994","journal-title":"Surgery"},{"key":"10.1016\/j.asjsur.2013.07.008_bib26","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1007\/s00268-004-7210-1","article-title":"Dependence of positive effects of granulocyte colony-stimulating factor on the antibiotic regimen: evaluation in rats with polymicrobial peritonitis","volume":"28","author":"Bauhofer","year":"2004","journal-title":"World J Surg."},{"key":"10.1016\/j.asjsur.2013.07.008_bib27","doi-asserted-by":"crossref","first-page":"130","DOI":"10.2144\/97221bi01","article-title":"Continuous fluorescence monitoring of rapid cycle DNA amplification","volume":"22","author":"Wittwer","year":"1997","journal-title":"Biotechniques"},{"key":"10.1016\/j.asjsur.2013.07.008_bib28","doi-asserted-by":"crossref","first-page":"176","DOI":"10.2144\/97221pf02","article-title":"The LightCycler: a microvolume multisample fluorimeter with rapid temperature control","volume":"22","author":"Wittwer","year":"1997","journal-title":"Biotechniques"},{"key":"10.1016\/j.asjsur.2013.07.008_bib29","first-page":"1694","article-title":"The value of omentoplasty in protecting colorectal anastomosis from leakage. A prospective randomized study in 126 patients","volume":"51","author":"Agnifili","year":"2004","journal-title":"Hepatogastroenterology."},{"key":"10.1016\/j.asjsur.2013.07.008_bib30","first-page":"601","article-title":"Reducing anastomotic leakage in oncologic colorectal surgery: an evidence-based review","volume":"30","author":"Boccola","year":"2010","journal-title":"Anticancer Res."},{"key":"10.1016\/j.asjsur.2013.07.008_bib31","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1007\/s00384-006-0260-0","article-title":"Risk factors for clinical anastomotic leakage and postoperative mortality in elective surgery for rectal cancer","volume":"22","author":"Kruschewski","year":"2007","journal-title":"Int J Colorectal Dis"},{"key":"10.1016\/j.asjsur.2013.07.008_bib32","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1007\/BF00496150","article-title":"A retrospective study of colostomies, leaks and strictures after colorectal anastomosis","volume":"5","author":"Tuson","year":"1990","journal-title":"Int J Colorectal Dis."},{"key":"10.1016\/j.asjsur.2013.07.008_bib33","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1007\/s10350-004-0869-4","article-title":"Prognosis after anastomotic leakage in colorectal surgery","volume":"48","author":"Branagan","year":"2005","journal-title":"Dis Colon Rectum."},{"key":"10.1016\/j.asjsur.2013.07.008_bib34","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1097\/01.sla.0000133186.81222.08","article-title":"Anastomotic leakage is predictive of diminished survival after potentially curative resection for colorectal cancer","volume":"240","author":"Walker","year":"2004","journal-title":"Ann Surg."},{"key":"10.1016\/j.asjsur.2013.07.008_bib35","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S1072-7515(97)00018-5","article-title":"Factors associated with the occurrence of leaks in stapled rectal anastomoses: a review of 1,014 patients","volume":"185","author":"Vignali","year":"1997","journal-title":"J Am Coll Surg."},{"key":"10.1016\/j.asjsur.2013.07.008_bib36","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1046\/j.1365-2168.1998.00615.x","article-title":"Risk factors for anastomotic leakage after resection of rectal cancer","volume":"85","author":"Rullier","year":"1998","journal-title":"Br J Surg."},{"key":"10.1016\/j.asjsur.2013.07.008_bib37","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1007\/s00384-003-0512-1","article-title":"Primary anastomosis after intraoperative colonic lavage vs. Hartmann's procedure in generalized peritonitis complicating diverticular disease of the colon","volume":"18","author":"Regenet","year":"2003","journal-title":"Int J Colorectal Dis."},{"key":"10.1016\/j.asjsur.2013.07.008_bib38","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/S0020-1383(00)00238-2","article-title":"Colonic injury: does colostomy still have a place?","volume":"32","author":"Miller","year":"2001","journal-title":"Injury."},{"key":"10.1016\/j.asjsur.2013.07.008_bib39","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1002\/bjs.4146","article-title":"Colonic anastomotic strength and matrix metalloproteinase activity in an experimental model of bacterial peritonitis","volume":"90","author":"de Hingh","year":"2003","journal-title":"Br J Surg."},{"key":"10.1016\/j.asjsur.2013.07.008_bib40","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1080\/00015458.2009.11680399","article-title":"Is Hartmann still alive?","volume":"109","author":"Vaneerdeweg","year":"2009","journal-title":"Acta Chir Belg."},{"key":"10.1016\/j.asjsur.2013.07.008_bib41","first-page":"316","article-title":"Hemostatic efficacy and safety of TachoComb in surgery. Ready to use and rapid hemostatic agent","volume":"81","author":"Agus","year":"1996","journal-title":"Int Surg."},{"key":"10.1016\/j.asjsur.2013.07.008_bib42","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1007\/BF02237248","article-title":"Altered microperfusion at the rectal stump is predictive for rectal anastomotic leak","volume":"43","author":"Vignali","year":"2000","journal-title":"Dis Colon Rectum."},{"key":"10.1016\/j.asjsur.2013.07.008_bib43","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1002\/bjs.1800780908","article-title":"Fibronectin and collagen gene expression in healing experimental colonic anastomoses","volume":"78","author":"Brasken","year":"1991","journal-title":"Br J Surg."},{"key":"10.1016\/j.asjsur.2013.07.008_bib44","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1111\/1523-1747.ep12276722","article-title":"Distinct populations of stromal cells express collagenase-3 (MMP-13) and collagenase-1 (MMP-1) in chronic ulcers but not in normally healing wounds","volume":"109","author":"Vaalamo","year":"1997","journal-title":"J Invest Dermatol."},{"key":"10.1016\/j.asjsur.2013.07.008_bib45","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1002\/bjs.1800771129","article-title":"Direct measurement of collagenase in colonic anastomosis","volume":"77","author":"Chowcat","year":"1990","journal-title":"Br J Surg."},{"key":"10.1016\/j.asjsur.2013.07.008_bib46","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1007\/BF02051206","article-title":"Role of matrix metalloproteinases in healing of colonic anastomosis","volume":"40","author":"Savage","year":"1997","journal-title":"Dis Colon Rectum."},{"key":"10.1016\/j.asjsur.2013.07.008_bib47","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/BF02553985","article-title":"Wound healing in the intestinal wall. A comparison between experimental ileal and colonic anastomoses","volume":"27","author":"Hesp","year":"1984","journal-title":"Dis Colon Rectum."},{"key":"10.1016\/j.asjsur.2013.07.008_bib48","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1007\/BF02047878","article-title":"Healing of ischemic colonic anastomosis: fibrin sealant does not improve wound healing","volume":"35","author":"van der Ham","year":"1992","journal-title":"Dis Colon Rectum."}],"container-title":["Asian Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1015958413000651?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1015958413000651?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T17:20:22Z","timestamp":1760894422000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1015958413000651"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":48,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["S1015958413000651"],"URL":"https:\/\/doi.org\/10.1016\/j.asjsur.2013.07.008","relation":{},"ISSN":["1015-9584"],"issn-type":[{"value":"1015-9584","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Anastomotic stability and wound healing of colorectal anastomoses sealed and sutured with a collagen fleece in a rat peritonitis model","name":"articletitle","label":"Article Title"},{"value":"Asian Journal of Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.asjsur.2013.07.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}