{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:48:06Z","timestamp":1760921286960,"version":"build-2065373602"},"reference-count":35,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,1,26]],"date-time":"2019-01-26T00:00:00Z","timestamp":1548460800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81172293"],"award-info":[{"award-number":["81172293"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Science and Technology Major Project of China","award":["2017ZX10203207-002"],"award-info":[{"award-number":["2017ZX10203207-002"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Asian Journal of Surgery"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1016\/j.asjsur.2019.01.009","type":"journal-article","created":{"date-parts":[[2019,2,16]],"date-time":"2019-02-16T07:50:41Z","timestamp":1550303441000},"page":"981-989","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Histologic severity of liver cirrhosis: A key factor affecting surgical outcomes of hepatocellular carcinoma in patients with portal hypertension"],"prefix":"10.1016","volume":"42","author":[{"given":"Ke-shuai","family":"Dong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin-yong","family":"Liang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zun-yi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Er-lei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shu-li","family":"Xia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-ping","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi-yong","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.asjsur.2019.01.009_bib1","first-page":"7","article-title":"Cancer statistics, 2016","volume":"66","author":"Siegel","year":"2016","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.asjsur.2019.01.009_bib2","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/j.jhep.2011.12.001","article-title":"EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma","volume":"56","year":"2012","journal-title":"J Hepatol"},{"key":"10.1016\/j.asjsur.2019.01.009_bib3","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1002\/bjs.8753","article-title":"Hepatic venous pressure gradient in the assessment of portal hypertension before liver resection in patients with cirrhosis","volume":"99","author":"Boleslawski","year":"2012","journal-title":"Br J Surg"},{"key":"10.1016\/j.asjsur.2019.01.009_bib4","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.7314\/APJCP.2014.15.4.1649","article-title":"Wen TF Influence of clinically significant portal hypertension on hepatectomy for hepatocellular carcinoma: a meta-analysis","volume":"15","author":"Tang","year":"2014","journal-title":"Asian Pac J Cancer Prev"},{"key":"10.1016\/j.asjsur.2019.01.009_bib5","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1002\/hep.27431","article-title":"Bruix J Portal hypertension and the outcome of surgery for hepatocellular carcinoma in compensated cirrhosis: a systematic review and meta-analysis","volume":"61","author":"Berzigotti","year":"2015","journal-title":"Hepatology"},{"key":"10.1016\/j.asjsur.2019.01.009_bib6","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1097\/SLA.0b013e3181b977a5","article-title":"Is portal hypertension a contraindication to hepatic resection?","volume":"250","author":"Cucchetti","year":"2009","journal-title":"Ann Surg"},{"key":"10.1016\/j.asjsur.2019.01.009_bib7","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1111\/j.1477-2574.2012.00594.x","article-title":"Hepatic resection for hepatocellular carcinoma in patients with Child-Pugh's A cirrhosis: is clinical evidence of portal hypertension a contraindication?","volume":"15","author":"Santambrogio","year":"2013","journal-title":"HPB (Oxford)"},{"key":"10.1016\/j.asjsur.2019.01.009_bib8","doi-asserted-by":"crossref","first-page":"e108755","DOI":"10.1371\/journal.pone.0108755","article-title":"Hepatic resection is safe and effective for patients with hepatocellular carcinoma and portal hypertension","volume":"9","author":"Zhong","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.asjsur.2019.01.009_bib9","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1186\/s12885-015-1280-3","article-title":"The role of clinically significant portal hypertension in hepatic resection for hepatocellular carcinoma patients: a propensity score matching analysis","volume":"15","author":"He","year":"2015","journal-title":"BMC Cancer"},{"key":"10.1016\/j.asjsur.2019.01.009_bib10","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1093\/jjco\/hyx007","article-title":"Progress of liver resection for hepatocellular carcinoma in Taiwan","volume":"47","author":"Wu","year":"2017","journal-title":"Jpn J Clin Oncol"},{"key":"10.1016\/j.asjsur.2019.01.009_bib11","doi-asserted-by":"crossref","first-page":"e495","DOI":"10.1097\/MD.0000000000000495","article-title":"Hepatic resection for hepatocellular carcinoma in patients with portal hypertension: a long-term benefit compared with transarterial chemoembolization and thermal ablation","volume":"94","author":"Xiao","year":"2015","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.asjsur.2019.01.009_bib12","first-page":"33","article-title":"Venook AP A review of hepatocellular carcinoma (HCC) staging systems","volume":"2","author":"Subramaniam","year":"2013","journal-title":"Chin Clin Oncol"},{"key":"10.1016\/j.asjsur.2019.01.009_bib13","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.jhep.2015.10.029","article-title":"Prognosis of hepatocellular carcinoma: assessment of eleven staging systems","volume":"64","author":"Liu","year":"2016","journal-title":"J Hepatol"},{"key":"10.1016\/j.asjsur.2019.01.009_bib14","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1002\/hep.24199","article-title":"Management of hepatocellular carcinoma: an update","volume":"53","author":"Bruix","year":"2011","journal-title":"Hepatology"},{"key":"10.1016\/j.asjsur.2019.01.009_bib15","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s00423-010-0700-8","article-title":"Chen XP Outcomes of non-anatomic liver resection for hepatocellular carcinoma in the patients with liver cirrhosis and analysis of prognostic factors","volume":"396","author":"Huang","year":"2011","journal-title":"Langenbecks Arch Surg"},{"key":"10.1016\/j.asjsur.2019.01.009_bib16","doi-asserted-by":"crossref","first-page":"e165059","DOI":"10.1001\/jamasurg.2016.5059","article-title":"Effect of background liver cirrhosis on outcomes of hepatectomy for hepatocellular carcinoma","volume":"152","author":"Sasaki","year":"2017","journal-title":"JAMA Surg"},{"key":"10.1016\/j.asjsur.2019.01.009_bib17","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1016\/j.jhep.2014.12.018","article-title":"Liver resection for hepatocellular carcinoma in 313 Western patients: tumor biology and underlying liver rather than tumor size drive prognosis","volume":"62","author":"Kluger","year":"2015","journal-title":"J Hepatol"},{"key":"10.1016\/j.asjsur.2019.01.009_bib18","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.surg.2015.09.002","article-title":"Severity of cirrhosis should determine the operative modality for patients with early hepatocellular carcinoma and compensated liver function","volume":"159","author":"Huang","year":"2016","journal-title":"Surgery"},{"key":"10.1016\/j.asjsur.2019.01.009_bib19","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1055\/s-2007-1007122","article-title":"Bruix J Prognosis of hepatocellular carcinoma: the BCLC staging classification","volume":"19","author":"Llovet","year":"1999","journal-title":"Semin Liver Dis"},{"key":"10.1016\/j.asjsur.2019.01.009_bib20","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.jhep.2012.04.029","article-title":"The Laennec staging system for histological sub-classification of cirrhosis is useful for stratification of prognosis in patients with liver cirrhosis","volume":"57","author":"Kim","year":"2012","journal-title":"J Hepatol"},{"key":"10.1016\/j.asjsur.2019.01.009_bib21","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1097\/01.sla.0000133083.54934.ae","article-title":"Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey","volume":"240","author":"Dindo","year":"2004","journal-title":"Ann Surg"},{"key":"10.1016\/j.asjsur.2019.01.009_bib22","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1097\/01.sla.0000189131.90876.9e","article-title":"The \u201c50\u201350 criteria\u201d on postoperative day 5: an accurate predictor of liver failure and death after hepatectomy","volume":"242","author":"Balzan","year":"2005","journal-title":"Ann Surg"},{"key":"10.1016\/j.asjsur.2019.01.009_bib23","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1002\/bjs.5335","article-title":"Chen YF Long-term outcome of resection of large hepatocellular carcinoma","volume":"93","author":"Chen","year":"2006","journal-title":"Br J Surg"},{"key":"10.1016\/j.asjsur.2019.01.009_bib24","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.1111\/liv.12199","article-title":"Influence of clinically significant portal hypertension on survival after hepatic resection for hepatocellular carcinoma in cirrhotic patients","volume":"33","author":"Giannini","year":"2013","journal-title":"Liver Int"},{"key":"10.1016\/j.asjsur.2019.01.009_bib25","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1097\/SLA.0000000000000236","article-title":"Hepatic resection associated with good survival for selected patients with intermediate and advanced-stage hepatocellular carcinoma","volume":"260","author":"Zhong","year":"2014","journal-title":"Ann Surg"},{"key":"10.1016\/j.asjsur.2019.01.009_bib26","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1002\/hep.27745","article-title":"The role of hepatic resection in the treatment of hepatocellular cancer","volume":"62","author":"Roayaie","year":"2015","journal-title":"Hepatology"},{"key":"10.1016\/j.asjsur.2019.01.009_bib27","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1002\/jhbp.423","article-title":"Validity of the barcelona clinic liver cancer and Hong Kong liver cancer staging systems for hepatocellular carcinoma in Singapore","volume":"24","author":"Selby","year":"2017","journal-title":"J Hepatobiliary Pancreat Sci"},{"key":"10.1016\/j.asjsur.2019.01.009_bib28","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1053\/j.gastro.2014.02.032","article-title":"Development of Hong Kong Liver Cancer staging system with treatment stratification for patients with hepatocellular carcinoma","volume":"146","author":"Yau","year":"2014","journal-title":"Gastroenterology"},{"key":"10.1016\/j.asjsur.2019.01.009_bib29","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1159\/000488035","article-title":"Guidelines for diagnosis and treatment of primary liver cancer in China (2017 edition)","volume":"7","author":"Zhou","year":"2018","journal-title":"Liver Cancer"},{"key":"10.1016\/j.asjsur.2019.01.009_bib30","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/s12876-017-0584-y","article-title":"Influence of cirrhosis on long-term prognosis after surgery in patients with combined hepatocellular-cholangiocarcinoma","volume":"17","author":"Zhou","year":"2017","journal-title":"BMC Gastroenterol"},{"key":"10.1016\/j.asjsur.2019.01.009_bib31","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.jss.2015.08.027","article-title":"Morphologic severity of cirrhosis determines the extent of liver resection in patients with hepatocellular carcinoma and Child-Pugh grade A cirrhosis","volume":"200","author":"Zhou","year":"2016","journal-title":"J Surg Res"},{"key":"10.1016\/j.asjsur.2019.01.009_bib32","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1111\/liv.12475","article-title":"Histological subclassification of cirrhosis can predict recurrence after curative resection of hepatocellular carcinoma","volume":"34","author":"Kim","year":"2014","journal-title":"Liver Int"},{"key":"10.1016\/j.asjsur.2019.01.009_bib33","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/s00423-018-1656-3","article-title":"Predicting morbidity of liver resection","volume":"403","author":"Madhavan","year":"2018","journal-title":"Langenbecks Arch Surg"},{"key":"10.1016\/j.asjsur.2019.01.009_bib34","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.jss.2016.04.036","article-title":"Predicting the severity of liver cirrhosis through clinical parameters","volume":"204","author":"Zhang","year":"2016","journal-title":"J Surg Res"},{"key":"10.1016\/j.asjsur.2019.01.009_bib35","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.jhep.2015.08.025","article-title":"Hepatic venous pressure gradient in the preoperative assessment of patients with resectable hepatocellular carcinoma","volume":"64","author":"Cucchetti","year":"2016","journal-title":"J Hepatol"}],"container-title":["Asian Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1015958418307814?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1015958418307814?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T17:22:29Z","timestamp":1760894549000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1015958418307814"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":35,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["S1015958418307814"],"URL":"https:\/\/doi.org\/10.1016\/j.asjsur.2019.01.009","relation":{},"ISSN":["1015-9584"],"issn-type":[{"type":"print","value":"1015-9584"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Histologic severity of liver cirrhosis: A key factor affecting surgical outcomes of hepatocellular carcinoma in patients with portal hypertension","name":"articletitle","label":"Article Title"},{"value":"Asian Journal of Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.asjsur.2019.01.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Asian Surgical Association and Taiwan Robotic Surgery Association. Publishing services by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}