{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T12:00:45Z","timestamp":1792670445249,"version":"4.5.0"},"reference-count":50,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,12,3]],"date-time":"2019-12-03T00:00:00Z","timestamp":1575331200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Asian Journal of Surgery"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1016\/j.asjsur.2019.11.012","type":"journal-article","created":{"date-parts":[[2020,1,18]],"date-time":"2020-01-18T07:46:11Z","timestamp":1579333571000},"page":"873-879","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Dexamethasone or combined with others for postoperative nausea and vomiting in children: A systematic review"],"prefix":"10.1016","volume":"43","author":[{"given":"Jieting","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huijuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiashan","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianjun","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiue","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kehu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.asjsur.2019.11.012_bib1","first-page":"617","article-title":"An update on the management of postoperative nausea and vomiting","volume":"31","author":"Cao","year":"2017","journal-title":"J\u00a0Anesth"},{"issue":"6","key":"10.1016\/j.asjsur.2019.11.012_bib2","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.ijom.2017.11.018","article-title":"Postoperative nausea and vomiting after oral and maxillofacial surgery: a prospective study","volume":"47","author":"Dobbeleir","year":"2018","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.asjsur.2019.11.012_bib3","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.ijsu.2015.01.024","article-title":"Post-operative nausea and vomiting: update on predicting the probability and ways to minimize its occurrence, with focus on ambulatory surgery","volume":"15","author":"Obrink","year":"2015","journal-title":"Int J Surg"},{"issue":"6","key":"10.1016\/j.asjsur.2019.11.012_bib4","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.ijom.2015.01.006","article-title":"Postoperative nausea and vomiting following orthognathic surgery","volume":"44","author":"Phillips","year":"2015","journal-title":"Int J Oral Maxillofac Surg"},{"issue":"4","key":"10.1016\/j.asjsur.2019.11.012_bib5","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1007\/BF03021038","article-title":"Dexamethasone reduces postoperative vomiting and pain after pediatric tonsillectomy","volume":"50","author":"Elhakim","year":"2003","journal-title":"Can J Anaesth."},{"issue":"1","key":"10.1016\/j.asjsur.2019.11.012_bib6","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1093\/bja\/83.1.104","article-title":"Postoperative nausea and vomiting in paediatric patients","volume":"83","author":"Rose","year":"1999","journal-title":"Br J Anaesth"},{"issue":"2","key":"10.1016\/j.asjsur.2019.11.012_bib7","first-page":"113","article-title":"The anesthetic management of the pediatric strabismus patient","volume":"2","author":"Williams","year":"1998","journal-title":"J\u00a0AAPOS : Off Publ Am Assoc Pediatr Ophthalmol Strabismus"},{"issue":"1","key":"10.1016\/j.asjsur.2019.11.012_bib8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0146746","article-title":"Gender-specific differences in low-dose haloperidol response for prevention of postoperative nausea and vomiting: a register-based cohort study","volume":"11","author":"Brettner","year":"2016","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.asjsur.2019.11.012_bib9","first-page":"269","article-title":"Anesthesia for pediatric ocular surgery","volume":"19","author":"Gayer","year":"2006","journal-title":"Ophthalmol Clin North Am"},{"issue":"6","key":"10.1016\/j.asjsur.2019.11.012_bib10","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1097\/00000542-198812000-00044","article-title":"Anesthetic complications following pediatric ambulatory surgery: a 3-yr study","volume":"69","author":"Patel","year":"1988","journal-title":"Anesthesiology"},{"issue":"1","key":"10.1016\/j.asjsur.2019.11.012_bib11","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1093\/bja\/aes173","article-title":"Using quality indicators in anaesthesia: feeding back data to improve care","volume":"109","author":"Benn","year":"2012","journal-title":"Br J Anaesth"},{"issue":"6","key":"10.1016\/j.asjsur.2019.11.012_bib12","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1177\/0310057X1003800619","article-title":"A\u00a0multi-centre multi-national survey of anaesthetists regarding the range of anaesthetic and surgical practices for paediatric scoliosis surgery","volume":"38","author":"Palmer","year":"2010","journal-title":"Anaesth Intensive Care"},{"issue":"6","key":"10.1016\/j.asjsur.2019.11.012_bib13","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1097\/ACO.0b013e32833ff302","article-title":"Preoperative single-dose intravenous dexamethasone during ambulatory surgery: update around the benefit versus risk","volume":"23","author":"Jakobsson","year":"2010","journal-title":"Curr Opin Anaesthesiol"},{"issue":"5","key":"10.1016\/j.asjsur.2019.11.012_bib14","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1111\/pan.12374","article-title":"Dexamethasone, ondansetron, and their combination and postoperative nausea and vomiting in children undergoing strabismus surgery: a meta-analysis of randomized controlled trials","volume":"24","author":"Shen","year":"2014","journal-title":"Paediatr Anaesth"},{"issue":"5","key":"10.1016\/j.asjsur.2019.11.012_bib15","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1093\/bja\/ael256","article-title":"Prophylaxis of postoperative vomiting in children undergoing tonsillectomy: a systematic review and meta-analysis","volume":"97","author":"Bolton","year":"2006","journal-title":"Br J Anaesth"},{"issue":"1","key":"10.1016\/j.asjsur.2019.11.012_bib16","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1038\/s41598-019-38764-8","article-title":"Effects of prophylactic dexamethasone on postoperative nausea and vomiting in scoliosis correction surgery: a double-blind, randomized, placebo-controlled clinical trial","volume":"9","author":"Wakamiya","year":"2019","journal-title":"Sci Rep"},{"key":"10.1016\/j.asjsur.2019.11.012_bib17","doi-asserted-by":"crossref","first-page":"8430","DOI":"10.12659\/MSM.911231","article-title":"Dexamethasone reduces the incidence of postoperative nausea and vomiting in children undergoing endoscopic adenoidectomy under general anesthesia without increasing the risk of postoperative hemorrhage","volume":"24","author":"Frelich","year":"2018","journal-title":"Med Sci Monit : Int Med J Exp Clin Res"},{"issue":"2","key":"10.1016\/j.asjsur.2019.11.012_bib18","doi-asserted-by":"crossref","first-page":"111","DOI":"10.5455\/medarh.2012.66.111-115","article-title":"Assessing intravenous ketamine and intravenous dexamethasone separately and in combination for early oral intake, vomiting and postoperative pain relief in children following tonsillectomy","volume":"66","author":"Safavi","year":"2012","journal-title":"Med Arh"},{"key":"10.1016\/j.asjsur.2019.11.012_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclinepi.2017.10.012","article-title":"Association between prospective registration and overall reporting and methodological quality of systematic reviews: a meta-epidemiological study","volume":"93","author":"Ge","year":"2018","journal-title":"J\u00a0Clin Epidemiol"},{"issue":"5","key":"10.1016\/j.asjsur.2019.11.012_bib20","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1016\/j.jclinepi.2014.12.009","article-title":"Systematic review found AMSTAR, but not R(evised)-AMSTAR, to have good measurement properties","volume":"68","author":"Pieper","year":"2015","journal-title":"J\u00a0Clin Epidemiol"},{"key":"10.1016\/j.asjsur.2019.11.012_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclinepi.2016.12.004","article-title":"The methodological and reporting quality of systematic reviews from China and the USA are similar","volume":"85","author":"Tian","year":"2017","journal-title":"J\u00a0Clin Epidemiol"},{"key":"10.1016\/j.asjsur.2019.11.012_bib22","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.jclinepi.2016.01.003","article-title":"The quality of evidence in Chinese meta-analyses needs to be improved","volume":"74","author":"Yao","year":"2016","journal-title":"J\u00a0Clin Epidemiol"},{"issue":"75","key":"10.1016\/j.asjsur.2019.11.012_bib23","doi-asserted-by":"crossref","first-page":"93","DOI":"10.4103\/1463-1741.153400","article-title":"Is there an association between aircraft noise exposure and the incidence of hypertension? A meta-analysis of 16784 participants","volume":"17","author":"Huang","year":"2015","journal-title":"Noise Health"},{"issue":"2","key":"10.1016\/j.asjsur.2019.11.012_bib24","first-page":"1","article-title":"Trace and evaluation systems for health services quality in rural and remote areas: a systematic review","volume":"26","author":"Li","year":"2017","journal-title":"J\u00a0Public Health"},{"issue":"1","key":"10.1016\/j.asjsur.2019.11.012_bib25","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1186\/s12966-018-0703-3","article-title":"Exercise training modalities in patients with type 2 diabetes mellitus: a systematic review and network meta-analysis","volume":"15","author":"Pan","year":"2018","journal-title":"Int J Behav Nutr Phys Act"},{"key":"10.1016\/j.asjsur.2019.11.012_bib26","doi-asserted-by":"crossref","first-page":"d5928","DOI":"10.1136\/bmj.d5928","article-title":"The Cochrane Collaboration's tool for assessing risk of bias in randomised trials","volume":"343","author":"Higgins","year":"2011","journal-title":"BMJ"},{"issue":"5","key":"10.1016\/j.asjsur.2019.11.012_bib27","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1177\/0310057X9902700509","article-title":"The effect of single dose intravenous dexamethasone in tonsillectomy in children","volume":"27","author":"Vosdoganis","year":"1999","journal-title":"Anaesth Intensive Care"},{"issue":"1","key":"10.1016\/j.asjsur.2019.11.012_bib28","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1093\/bja\/86.1.84","article-title":"Dexamethasone is a cost-effective alternative to ondansetron in preventing PONV after paediatric strabismus repair","volume":"86","author":"Subramaniam","year":"2001","journal-title":"Br J Anaesth"},{"issue":"11","key":"10.1016\/j.asjsur.2019.11.012_bib29","first-page":"1636","article-title":"Use of dexamethasone to reduce postoperative vomiting and pain after pediatric tonsillectomy procedures","volume":"25","author":"Samarkandi","year":"2004","journal-title":"Saudi Med J"},{"issue":"3","key":"10.1016\/j.asjsur.2019.11.012_bib30","first-page":"431","article-title":"Combination therapy in the prevention of PONV after strabismus surgery in children: granisetron, ondansetron, midazolam with dexamethasone","volume":"20","author":"Riad","year":"2009","journal-title":"Middle East J Anesthesiol"},{"issue":"8","key":"10.1016\/j.asjsur.2019.11.012_bib31","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1017\/S0265021507000166","article-title":"Effect of midazolam, dexamethasone and their combination on the prevention of nausea and vomiting following strabismus repair in children","volume":"24","author":"Riad","year":"2007","journal-title":"Eur J Anaesthesiol"},{"issue":"1","key":"10.1016\/j.asjsur.2019.11.012_bib32","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1213\/00000539-199807000-00013","article-title":"The effect of preoperative dexamethasone on the immediate and delayed postoperative morbidity in children undergoing adenotonsillectomy","volume":"87","author":"Pappas","year":"1998","journal-title":"Anesth Analg"},{"issue":"1","key":"10.1016\/j.asjsur.2019.11.012_bib33","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1007\/s12630-011-9616-1","article-title":"Effect of dexamethasone on postoperative morbidity after dental rehabilitation in children","volume":"59","author":"McIntyre","year":"2012","journal-title":"Can J Anaesth."},{"issue":"6","key":"10.1016\/j.asjsur.2019.11.012_bib34","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1213\/01.ANE.0000150977.14607.E1","article-title":"Prophylactic dexamethasone for postoperative nausea and vomiting in pediatric strabismus surgery: a dose ranging and safety evaluation study","volume":"100","author":"Madan","year":"2005","journal-title":"Anesth Analg"},{"issue":"11","key":"10.1016\/j.asjsur.2019.11.012_bib35","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1016\/j.ijporl.2009.06.001","article-title":"Determination of optimum dosage of intraoperative single dose dexamethasone in pediatric tonsillectomy and adenotonsillectomy","volume":"73","author":"Karaman","year":"2009","journal-title":"Int J Pediatr Otorhinolaryngol"},{"issue":"1","key":"10.1016\/j.asjsur.2019.11.012_bib36","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.ijporl.2005.05.013","article-title":"The effect of preoperative dexamethasone on early oral intake, vomiting and pain after tonsillectomy","volume":"70","author":"Kaan","year":"2006","journal-title":"Int J Pediatr Otorhinolaryngol"},{"issue":"5","key":"10.1016\/j.asjsur.2019.11.012_bib37","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1111\/j.1399-6576.2007.01296.x","article-title":"Superior anti-emetic efficacy of granisetron-dexamethasone combination in children undergoing middle ear surgery","volume":"51","author":"Gombar","year":"2007","journal-title":"Acta Anaesthesiol Scand"},{"issue":"3","key":"10.1016\/j.asjsur.2019.11.012_bib38","first-page":"235","article-title":"Intra operative use of anti emetic drugs for children undergoing full dental rehabilitation under general anesthesia. A double blind randomized clinical trial","volume":"40","author":"El Batawi","year":"2016","journal-title":"J\u00a0Clin Pediatr Dent"},{"issue":"9","key":"10.1016\/j.asjsur.2019.11.012_bib39","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1111\/j.1460-9592.2012.03900.x","article-title":"Dexamethasone versus ondansetron in combination with dexamethasone for the prophylaxis of postoperative vomiting in pediatric outpatients: a double-blind, randomized, placebo-controlled clinical trial","volume":"22","author":"de Orange","year":"2012","journal-title":"Paediatr Anaesth"},{"issue":"22","key":"10.1016\/j.asjsur.2019.11.012_bib40","doi-asserted-by":"crossref","first-page":"2621","DOI":"10.1001\/jama.2008.794","article-title":"Dexamethasone and risk of nausea and vomiting and postoperative bleeding after tonsillectomy in children: a randomized trial","volume":"300","author":"Czarnetzki","year":"2008","journal-title":"Jama"},{"issue":"2","key":"10.1016\/j.asjsur.2019.11.012_bib41","doi-asserted-by":"crossref","first-page":"100","DOI":"10.3928\/0191-3913-20040301-10","article-title":"Comparison of ondansetron with ondansetron plus dexamethasone for antiemetic prophylaxis in children undergoing strabismus surgery","volume":"41","author":"Bhardwaj","year":"2004","journal-title":"J\u00a0Pediatr Ophthalmol Strabismus"},{"issue":"3","key":"10.1016\/j.asjsur.2019.11.012_bib42","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1213\/00000539-200103000-00015","article-title":"The effect of dexamethasone on postoperative vomiting after tonsillectomy","volume":"92","author":"Aouad","year":"2001","journal-title":"Anesth Analg"},{"issue":"6","key":"10.1016\/j.asjsur.2019.11.012_bib43","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1097\/SLA.0000000000001112","article-title":"Efficacy of a single preoperative dexamethasone dose to prevent nausea and vomiting after thyroidectomy (the tPONV study): a randomized, double-blind, placebo-controlled clinical trial","volume":"262","author":"Tarantino","year":"2015","journal-title":"Ann Surg"},{"issue":"3","key":"10.1016\/j.asjsur.2019.11.012_bib44","first-page":"397","article-title":"Effect of prophylactic dexamethasone on nausea and vomiting after laparoscopic gynecological operation: meta-analysis","volume":"21","author":"Wang","year":"2011","journal-title":"Middle East J Anesthesiol"},{"issue":"5","key":"10.1016\/j.asjsur.2019.11.012_bib45","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1097\/SLA.0b013e3181856024","article-title":"The impact of prophylactic dexamethasone on nausea and vomiting after laparoscopic cholecystectomy: a systematic review and meta-analysis","volume":"248","author":"Karanicolas","year":"2008","journal-title":"Ann Surg"},{"key":"10.1016\/j.asjsur.2019.11.012_bib46","first-page":"j1455","article-title":"Dexamethasone versus standard treatment for postoperative nausea and vomiting in gastrointestinal surgery: randomised controlled trial (DREAMS Trial)","volume":"357","year":"2017","journal-title":"Bmj"},{"issue":"Pt A","key":"10.1016\/j.asjsur.2019.11.012_bib47","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.ijsu.2016.10.034","article-title":"Dexamethasone combined with other antiemetics versus single antiemetics for prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy: an updated systematic review and meta-analysis","volume":"36","author":"Awad","year":"2016","journal-title":"Int J Surg"},{"issue":"1","key":"10.1016\/j.asjsur.2019.11.012_bib48","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1093\/bja\/aeu152","article-title":"Dexamethasone and haemorrhage risk in paediatric tonsillectomy: a systematic review and meta-analysis","volume":"113","author":"Bellis","year":"2014","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.asjsur.2019.11.012_bib49","first-page":"Cd011940","article-title":"Adverse side effects of dexamethasone in surgical patients","volume":"8","author":"Polderman","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.asjsur.2019.11.012_bib50","series-title":"The Pharmacological Basis of Therapeutics","first-page":"1447","article-title":"Adrenocorticotropic hormone: adrenocortical steroids and their synthetic analogs-inhibitors of the synthesis and actions of adrenocortical hormones","author":"Haynes","year":"1990"}],"container-title":["Asian Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1015958419308577?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1015958419308577?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T17:23:02Z","timestamp":1760894582000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1015958419308577"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":50,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["S1015958419308577"],"URL":"https:\/\/doi.org\/10.1016\/j.asjsur.2019.11.012","relation":{},"ISSN":["1015-9584"],"issn-type":[{"value":"1015-9584","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dexamethasone or combined with others for postoperative nausea and vomiting in children: A systematic review","name":"articletitle","label":"Article Title"},{"value":"Asian Journal of Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.asjsur.2019.11.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Asian Surgical Association and Taiwan Robotic Surgery Association. Publishing services by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}