{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T10:39:31Z","timestamp":1773571171701,"version":"3.50.1"},"reference-count":34,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,7,8]],"date-time":"2023-07-08T00:00:00Z","timestamp":1688774400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2023,7,8]],"date-time":"2023-07-08T00:00:00Z","timestamp":1688774400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2023,7,8]],"date-time":"2023-07-08T00:00:00Z","timestamp":1688774400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,7,8]],"date-time":"2023-07-08T00:00:00Z","timestamp":1688774400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T00:00:00Z","timestamp":1686787200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["arthroscopysportsmedicineandrehabilitation.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Arthroscopy, Sports Medicine, and Rehabil."],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To report rates of preoperative and postoperative opioid use between male and female patients and to identify risk factors for extended opioid use following anterior cruciate ligament reconstruction (ACLR).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients undergoing ACLR between 2011 and 2018 were identified from the PearlDiver database. The opioid refill rates for males vs females were compared at monthly intervals for 1 year after ACLR. Patients who filled an opioid prescription &lt;3 months before surgery were classified as opioid users, while those who had never filled one were classified as nonopioid users.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 106,995 ACLR patients, 37,890 (35.4%) were opioid users &lt;3 months before surgery, and 37,554 (35.1%) had never filled an opioid prescription. Of the preoperative opioid users, 20,413 (53.9%) were female and 17,477 (46.1%) were male (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .001). Postoperatively, females were at higher risk of filling an opioid prescription at each monthly interval, except for the first month after surgery. The refill rate for opioid users was also higher than that for nonopioid users at each monthly interval after ACLR. In addition to patient sex, a preoperative diagnosis of anxiety\/depression, low back pain, myalgia, a history of drug dependence, alcohol abuse, and tobacco use increased a patient\u2019s risk of filling an opioid prescription postoperatively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study demonstrated that females are significantly more likely to be opioid users than males prior to ACLR and are more likely to continue to refill an opioid prescription in the year following surgery. Multiple risk factors were associated with prolonged postoperative opioid utilization, including female sex, anxiety\/depression, low back pain, myalgia, a history of drug dependence, alcohol abuse, and tobacco use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level III, retrospective cohort study.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.asmr.2023.100758","type":"journal-article","created":{"date-parts":[[2023,7,8]],"date-time":"2023-07-08T15:14:55Z","timestamp":1688829295000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Females Are More Likely Than Males to Fill an Opioid Prescription in the Year After Anterior Cruciate Ligament Reconstruction"],"prefix":"10.1002","volume":"5","author":[{"given":"Patrick J.","family":"Meade","sequence":"first","affiliation":[{"name":"Tulane University School of Medicine New Orleans Louisiana U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chelsea N.","family":"Matzko","sequence":"additional","affiliation":[{"name":"Tulane University School of Medicine New Orleans Louisiana U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michaela A.","family":"Stamm","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Tulane University School of Medicine New Orleans Louisiana U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary K.","family":"Mulcahey","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Tulane University School of Medicine New Orleans Louisiana U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,7,8]]},"reference":[{"key":"e_1_2_2_2_2","unstructured":"Centers for Disease Control and Prevention.Wide\u2010ranging online data for epidemiologic research (WONDER)http:\/\/wonder.cdc.gov\/. Accessed November 11 2021."},{"key":"e_1_2_2_3_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5530-09.2010"},{"key":"e_1_2_2_4_2","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000002458"},{"key":"e_1_2_2_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000003742"},{"key":"e_1_2_2_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/YCO.0000000000000337"},{"key":"e_1_2_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2009.07.016"},{"key":"e_1_2_2_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13293-019-0237-7"},{"key":"e_1_2_2_9_2","unstructured":"Centers for Disease Control and Prevention.Multiple cause of death 1999\u20102016 on CDC WONDER Online Database released 2017https:\/\/wonder.cdc.gov\/mcd\u2010icd10.html. Accessed November 11 2021."},{"key":"e_1_2_2_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2017.3132"},{"key":"e_1_2_2_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/CORR.0000000000001251"},{"key":"e_1_2_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2015.12.008"},{"key":"e_1_2_2_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/JOM.0000000000000352"},{"key":"e_1_2_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2020.04.018"},{"key":"e_1_2_2_15_2","doi-asserted-by":"publisher","DOI":"10.2147\/OAJSM.S266227"},{"key":"e_1_2_2_16_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546515617737"},{"issue":"2","key":"e_1_2_2_17_2","first-page":"268","article-title":"ACL reconstruction\u2014it\u2019s all about timing","volume":"9","author":"Evans S.","year":"2014","journal-title":"Int J Sport Phys Ther"},{"key":"e_1_2_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2017.03.014"},{"key":"e_1_2_2_19_2","doi-asserted-by":"publisher","DOI":"10.1177\/1941738120954432"},{"key":"e_1_2_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2017.08.010"},{"key":"e_1_2_2_21_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546519854754"},{"key":"e_1_2_2_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2018.08.056"},{"key":"e_1_2_2_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2017.10.060"},{"key":"e_1_2_2_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2009.01.002"},{"key":"e_1_2_2_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2017.04.002"},{"key":"e_1_2_2_26_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm655051e1"},{"key":"e_1_2_2_27_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-015-4173-5"},{"issue":"6","key":"e_1_2_2_28_2","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1007\/s00264-014-2298-x","article-title":"Opioid use prior to total hip arthroplasty leads to worse clinical outcomes","volume":"38","author":"Pivce R.","year":"2014","journal-title":"Int Orthop"},{"key":"e_1_2_2_29_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa1807069"},{"key":"e_1_2_2_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2017.04.002"},{"key":"e_1_2_2_31_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546517719226"},{"key":"e_1_2_2_32_2","first-page":"1","article-title":"The effectiveness and risks of long\u2010term opioid treatment of chronic pain","volume":"218","author":"Chou R.","year":"2014","journal-title":"Evid Rep Technol Assess (Full Rep)"},{"key":"e_1_2_2_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2020.108414"},{"key":"e_1_2_2_34_2","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000003976"},{"key":"e_1_2_2_35_2","doi-asserted-by":"publisher","DOI":"10.1002\/pmrj.12007"}],"container-title":["Arthroscopy, Sports Medicine, and Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666061X23001086?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666061X23001086?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/arthroscopyjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.asmr.2023.100758","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/arthroscopyjournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1016\/j.asmr.2023.100758","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/arthroscopyjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.asmr.2023.100758","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T09:16:21Z","timestamp":1773566181000},"score":1,"resource":{"primary":{"URL":"https:\/\/arthroscopyjournals.onlinelibrary.wiley.com\/doi\/10.1016\/j.asmr.2023.100758"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,8]]},"references-count":34,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["10.1016\/j.asmr.2023.100758"],"URL":"https:\/\/doi.org\/10.1016\/j.asmr.2023.100758","archive":["Portico"],"relation":{},"ISSN":["2666-061X","2666-061X"],"issn-type":[{"value":"2666-061X","type":"print"},{"value":"2666-061X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Females Are More Likely Than Males to Fill an Opioid Prescription in the Year After Anterior Cruciate Ligament Reconstruction","name":"articletitle","label":"Article Title"},{"value":"Arthroscopy, Sports Medicine, and Rehabilitation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.asmr.2023.100758","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Inc. on behalf of the Arthroscopy Association of North America.","name":"copyright","label":"Copyright"}],"article-number":"100758"}}