{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T08:02:51Z","timestamp":1778659371380,"version":"3.51.4"},"reference-count":51,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100007947","name":"Universit\u00e4tsbund Erlangen-N\u00fcrnberg","doi-asserted-by":"publisher","award":["B40\/A11"],"award-info":[{"award-number":["B40\/A11"]}],"id":[{"id":"10.13039\/501100007947","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009379","name":"Interdisziplin\u00e4res Zentrum f\u00fcr Klinische Forschung, Universit\u00e4tsklinikum W\u00fcrzburg","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009379","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["atherosclerosis-journal.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Atherosclerosis"],"published-print":{"date-parts":[[2007,1]]},"DOI":"10.1016\/j.atherosclerosis.2006.01.014","type":"journal-article","created":{"date-parts":[[2006,2,22]],"date-time":"2006-02-22T07:25:10Z","timestamp":1140593110000},"page":"156-166","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["CD40\u2013CD154 expression in calcified and non-calcified coronary lesions of patients with chronic renal failure"],"prefix":"10.1016","volume":"190","author":[{"given":"Valentina","family":"Campean","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Neureiter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Nonnast-Daniel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Garlichs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie-Luise","family":"Gross","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kerstin","family":"Amann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib1","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/S0272-6386(96)90363-7","article-title":"Electron beam computed tomography in the evaluation of cardiac calcification in chronic dialysis patients","volume":"27","author":"Braun","year":"1996","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib2","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1056\/NEJM200005183422003","article-title":"Coronary-artery calcification in young adults with end-stage renal disease who are undergoing dialysis","volume":"342","author":"Goodman","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib3","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1056\/NEJM197403282901301","article-title":"Accelerated atherosclerosis in prolonged maintenance hemodialysis","volume":"290","author":"Lindner","year":"1974","journal-title":"N Engl J Med"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib4","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1161\/01.CIR.0000020222.63035.C0","article-title":"Advanced coronary and carotid arteriopathy in young adults with childhood-onset chronic renal failure","volume":"106","author":"Oh","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib5","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1053\/j.ajkd.2003.12.005","article-title":"Vascular calcification in chronic kidney disease","volume":"43","author":"Goodman","year":"2004","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib6","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/S0735-1097(01)01781-8","article-title":"Cardiac calcification in adult hemodialysis patients. A link between end-stage renal disease and cardiovascular disease?","volume":"39","author":"Raggi","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib7","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1093\/ndt\/15.2.218","article-title":"Morphology of coronary atherosclerotic lesions in patients with end-stage renal failure","volume":"15","author":"Schwarz","year":"2000","journal-title":"Nephrol Dial Transpl"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib8","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1046\/j.1523-1755.2002.00170.x","article-title":"Medial artery calcification in ESRD patients is associated with deposition of bone matrix proteins","volume":"61","author":"Moe","year":"2002","journal-title":"Kidney Int"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib9","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1038\/ki.1979.170","article-title":"Ischemic heart disease in patients with uremia undergoing maintenance hemodialysis","volume":"16","author":"Rostand","year":"1979","journal-title":"Kidney Int"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib10","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1097\/01.ASN.0000115398.92270.30","article-title":"Overview: increased cardiovascular risk in patients with minor renal dysfunction: an emerging issue with far-reaching consequences","volume":"15","author":"Ritz","year":"2004","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib11","doi-asserted-by":"crossref","first-page":"2154","DOI":"10.1161\/01.CIR.0000095676.90936.80","article-title":"Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on kidney in cardiovascular disease, high blood pressure research, clinical cardiology, and epidemiology and prevention","volume":"108","author":"Sarnak","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib12","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1046\/j.1523-1755.1999.00273.x","article-title":"Inflammation enhances cardiovascular risk and mortality in hemodialysis patients","volume":"55","author":"Zimmermann","year":"1999","journal-title":"Kidney Int"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib13","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1097\/01.ASN.0000045048.71975.FC","article-title":"The apolipoprotein e knockout mouse: a model documenting accelerated atherogenesis in uremia","volume":"14","author":"Buzello","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib14","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1111\/j.1523-1755.2004.00465.x","article-title":"Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease","volume":"65","author":"Oberg","year":"2004","journal-title":"Kidney Int"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib15","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1161\/01.CIR.0000042700.48769.59","article-title":"Elevations of inflammatory and procoagulant biomarkers in elderly persons with renal insufficiency","volume":"107","author":"Shlipak","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib16","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1053\/j.ajkd.2003.10.037","article-title":"Inflammation, endothelial dysfunction, and platelet activation in patients with chronic kidney disease: the chronic renal impairment in Birmingham (CRIB) study","volume":"43","author":"Landray","year":"2004","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib17","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1172\/JCI10373","article-title":"NF-kappaB: pivotal mediator or innocent bystander in atherogenesis?","volume":"107","author":"Collins","year":"2001","journal-title":"J Clin Invest"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib18","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0014-5793(99)00683-3","article-title":"Cytokine-inducible CD40 gene expression in vascular smooth muscle cells is mediated by nuclear factor kappaB and signal transducer and activation of transcription-1","volume":"453","author":"Krzesz","year":"1999","journal-title":"FEBS Lett"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib19","doi-asserted-by":"crossref","first-page":"25032","DOI":"10.1074\/jbc.M204003200","article-title":"Induction of tissue factor expression in human endothelial cells by CD40 ligand is mediated via activator protein 1, nuclear factor kappaB, and Egr-1","volume":"277","author":"Bavendiek","year":"2002","journal-title":"J Biol Chem"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib20","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1056\/NEJM199901143400207","article-title":"Atherosclerosis\u2014an inflammatory disease","volume":"340","author":"Ross","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib21","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1161\/01.RES.0000029784.15893.10","article-title":"Innate and adaptive immunity in the pathogenesis of atherosclerosis","volume":"91","author":"Hansson","year":"2002","journal-title":"Circ Res"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib22","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1038\/nature01323","article-title":"Inflammation in atherosclerosis","volume":"420","author":"Libby","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib23","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1161\/CIRCULATIONAHA.105.556530","article-title":"Native C-reactive protein (CRP) increases, whereas modified CRP reduces atherosclerosis in ApoE-knockout-mice","volume":"112","author":"Schwedler","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib24","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1002\/path.1425","article-title":"CD40 ligand is selectively expressed on CD4+ T cells and platelets: implications for CD40\u2013CD40L signalling in atherosclerosis","volume":"201","author":"Buchner","year":"2003","journal-title":"J Pathol"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib25","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/S1357-2725(00)00016-9","article-title":"CD154 (CD40 ligand)","volume":"32","author":"Schonbeck","year":"2000","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib26","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1161\/hh2401.101272","article-title":"CD40 signaling and plaque instability","volume":"89","author":"Schonbeck","year":"2001","journal-title":"Circ Res"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib27","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/S0008-6363(03)00341-9","article-title":"T lymphocytes in atherogenesis-functional aspects and antigenic repertoire","volume":"60","author":"de Boer","year":"2003","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib28","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1007\/s004280000239","volume":"437","author":"Hakkinen","year":"2000","journal-title":"Virchows Arch"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib29","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0002-9149(00)01266-2","article-title":"Expression of CD40 in vascular smooth muscle cells and macrophages is associated with early development of human atherosclerotic lesions","volume":"87","author":"Bruemmer","year":"2001","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib30","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1038\/15271","article-title":"Requirement for CD154 in the progression of atherosclerosis","volume":"5","author":"Lutgens","year":"1999","journal-title":"Nat Med"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib31","doi-asserted-by":"crossref","first-page":"7464","DOI":"10.1073\/pnas.97.13.7464","article-title":"Both early and delayed anti-CD40L antibody treatment induces a stable plaque phenotype","volume":"97","author":"Lutgens","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib32","doi-asserted-by":"crossref","first-page":"2266","DOI":"10.1161\/hc4401.099447","article-title":"Soluble CD40L and cardiovascular risk in women","volume":"104","author":"Schonbeck","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib33","doi-asserted-by":"crossref","first-page":"16E","DOI":"10.1016\/S0002-9149(01)01713-1","article-title":"The development of calcium deposits in atherosclerotic lesions and their persistence after lipid regression","volume":"88","author":"Stary","year":"2001","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib34","doi-asserted-by":"crossref","DOI":"10.1007\/s10016-005-0003-7","article-title":"Overexpression of MMP9 and tissue factor in unstable carotid plaques associated with Chlamydia pneumoniae, inflammation, and apoptosis","author":"Stintzing","year":"2005","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib35","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0021-9150(03)00085-6","article-title":"Detection of Chlamydia pneumoniae but not of Helicobacter pylori in symptomatic atherosclerotic carotids associated with enhanced serum antibodies, inflammation and apoptosis rate","volume":"168","author":"Neureiter","year":"2003","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib36","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1038\/28204","article-title":"Reduction of atherosclerosis in mice by inhibition of CD40 signalling","volume":"394","author":"Mach","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib37","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.1073\/pnas.94.5.1931","article-title":"Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for CD40\u2013CD40 ligand signaling in atherosclerosis","volume":"94","author":"Mach","year":"1997","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib38","doi-asserted-by":"crossref","first-page":"4342","DOI":"10.1073\/pnas.92.10.4342","article-title":"CD40 on human endothelial cells: inducibility by cytokines and functional regulation of adhesion molecule expression","volume":"92","author":"Karmann","year":"1995","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib39","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/S0008-6363(98)00255-7","article-title":"Leucocyte recruitment in rupture prone regions of lipid-rich plaques: a prominent role for neovascularization?","volume":"41","author":"de Boer","year":"1999","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib40","first-page":"III30","article-title":"Why do plaques rupture?","volume":"86","author":"Falk","year":"1992","journal-title":"Circulation"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib41","first-page":"463","article-title":"Fibrous and lipid-rich atherosclerotic plaques are part of interchangeable morphologies related to inflammation: a concept","volume":"5","author":"van der Wal","year":"1994","journal-title":"Coron Artery Dis"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib42","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s004280000215","article-title":"Analysis of CD154 and CD40 expression in native coronary atherosclerosis and transplant associated coronary artery disease","volume":"437","author":"Szabolcs","year":"2000","journal-title":"Virchows Arch"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib43","doi-asserted-by":"crossref","first-page":"4815","DOI":"10.4049\/jimmunol.156.12.4815","article-title":"Expression of C-reactive protein by alveolar macrophages","volume":"156","author":"Dong","year":"1996","journal-title":"J Immunol"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib44","first-page":"117","article-title":"Human alveolar macrophages and monocytes generate the functional classical pathway of complement in vitro","volume":"95","author":"Hetland","year":"1987","journal-title":"Acta Pathol Microbiol Immunol Scand [C]"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib45","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1097\/00004872-199917020-00008","article-title":"Influence of age and end-stage renal disease on the stiffness of carotid wall material in hypertension","volume":"17","author":"Blacher","year":"1999","journal-title":"J Hypertens"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib46","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1053\/ajkd.1998.v31.pm9531176","article-title":"Association of serum phosphorus and calcium\u00d7phosphate product with mortality risk in chronic hemodialysis patients: a national study","volume":"31","author":"Block","year":"1998","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib47","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1093\/ndt\/gfh125","article-title":"Determinants of progressive vascular calcification in haemodialysis patients","volume":"19","author":"Chertow","year":"2004","journal-title":"Nephrol Dial Transpl"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib48","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1161\/01.CIR.0000125690.80303.A8","article-title":"Clinical usefulness of very high and very low levels of C-reactive protein across the full range of Framingham risk scores","volume":"109","author":"Ridker","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib49","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1161\/01.CIR.0000088521.04017.13","article-title":"Soluble CD40L: risk prediction after acute coronary syndromes","volume":"108","author":"Varo","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib50","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1056\/NEJMoa022600","article-title":"Soluble CD40 ligand in acute coronary syndromes","volume":"348","author":"Heeschen","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.atherosclerosis.2006.01.014_bib51","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1097\/00001721-200408000-00004","article-title":"Increased soluble CD40L levels are reduced by long-term simvastatin treatment in peritoneally dialyzed patients","volume":"15","author":"Malyszko","year":"2004","journal-title":"Blood Coagul Fibrin"}],"container-title":["Atherosclerosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021915006000359?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021915006000359?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T00:28:28Z","timestamp":1758155308000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021915006000359"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,1]]},"references-count":51,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,1]]}},"alternative-id":["S0021915006000359"],"URL":"https:\/\/doi.org\/10.1016\/j.atherosclerosis.2006.01.014","relation":{},"ISSN":["0021-9150"],"issn-type":[{"value":"0021-9150","type":"print"}],"subject":[],"published":{"date-parts":[[2007,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"CD40\u2013CD154 expression in calcified and non-calcified coronary lesions of patients with chronic renal failure","name":"articletitle","label":"Article Title"},{"value":"Atherosclerosis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.atherosclerosis.2006.01.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}