{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T02:26:08Z","timestamp":1793413568429,"version":"4.5.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Atherosclerosis"],"published-print":{"date-parts":[[2010,1]]},"DOI":"10.1016\/j.atherosclerosis.2009.07.032","type":"journal-article","created":{"date-parts":[[2009,7,24]],"date-time":"2009-07-24T08:51:37Z","timestamp":1248425497000},"page":"290-296","source":"Crossref","is-referenced-by-count":53,"title":["Fetuin-A and CD40 L plasma levels in acute ischemic stroke: Differences in relation to TOAST subtype and correlation with clinical and laboratory variables"],"prefix":"10.1016","volume":"208","author":[{"given":"A.","family":"Tuttolomondo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Di Raimondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Di Sciacca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Casuccio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Bivona","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Bellia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Barreca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Serio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"D\u2019Aguanno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Ciaccio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Licata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Pinto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"November (1)","key":"10.1016\/j.atherosclerosis.2009.07.032_bib1","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.atherosclerosis.2006.08.052","article-title":"Association of high alpha2-Heremans-Schmid glycoprotein\/fetuin concentration in serum and intima-media thickness in patients with atherosclerotic vascular disease and low bone mass","volume":"195","author":"Fiore","year":"2007","journal-title":"Atherosclerosis"},{"issue":"August (3)","key":"10.1016\/j.atherosclerosis.2009.07.032_bib2","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1172\/JCI17202","article-title":"The serum protein alpha 2-Heremans-Schmid glycoprotein\/fetuin-A is a systemically acting inhibitor of ectopic calcification","volume":"112","author":"Schafer","year":"2003","journal-title":"J Clin Invest"},{"key":"10.1016\/j.atherosclerosis.2009.07.032_bib3","doi-asserted-by":"crossref","first-page":"20789","DOI":"10.1074\/jbc.271.34.20789","article-title":"The serum protein alpha 2 -HS glycoprotein\/fetuin inhibits apatite formation in vitro and in mineralizing calvaria cells: a possible role in mineralization and calcium homeostasis","volume":"271","author":"Schinke","year":"1996","journal-title":"J Biol Chem"},{"issue":"6","key":"10.1016\/j.atherosclerosis.2009.07.032_bib4","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1093\/ndt\/gfm094","article-title":"Fetuin-A (AHSG) prevents extraosseous calcification induced by uraemia and phosphate challenge in mice","volume":"22","author":"Westenfeld","year":"2007","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.atherosclerosis.2009.07.032_bib5","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1159\/000082013","article-title":"Inflammation and vascular calcification","volume":"23","author":"Moe","year":"2005","journal-title":"Blood Purif"},{"key":"10.1016\/j.atherosclerosis.2009.07.032_bib6","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/S0140-6736(03)12710-9","article-title":"Association of low fetuin-A (AHSG) concentrations in serum with cardiovascular mortality in patients on dialysis: a cross-sectional study","volume":"361","author":"Ketteler","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.atherosclerosis.2009.07.032_bib7","doi-asserted-by":"crossref","first-page":"2283","DOI":"10.1111\/j.1523-1755.2005.00345.x","article-title":"Low fetuin-A levels are associated with cardiovascular death: impact of variations of gene encoding fetuin","volume":"67","author":"Stenvinkel","year":"2005","journal-title":"Kidney Int"},{"key":"10.1016\/j.atherosclerosis.2009.07.032_bib8","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1084\/jem.178.2.669","article-title":"CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand for CD40","volume":"178","author":"Alderson","year":"1993","journal-title":"J Exp Med"},{"key":"10.1016\/j.atherosclerosis.2009.07.032_bib9","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1097\/00007890-199712270-00025","article-title":"CD40 and CD40 ligand (CD154) are coexpressed on microvessels in vivo in human cardiac allograft rejection","volume":"64","author":"Reul","year":"1997","journal-title":"Transplantation"},{"key":"10.1016\/j.atherosclerosis.2009.07.032_bib10","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.1073\/pnas.94.5.1931","article-title":"Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for CD40-CD40 ligand signaling in atherosclerosis","volume":"94","author":"Mach","year":"1997","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.atherosclerosis.2009.07.032_bib11","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1038\/35393","article-title":"CD40-ligand on activated platelets triggers an inflammatory reaction of endothelial cells","volume":"391","author":"Henn","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.atherosclerosis.2009.07.032_bib12","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1161\/CIRCULATIONAHA.105.588723","article-title":"Association between human fetuin-A and the metabolic syndrome: data from the Heart and Soul Study","volume":"113","author":"Ix","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.atherosclerosis.2009.07.032_bib13","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1210\/er.2006-0033","article-title":"Adipose tissue-derived factors: impact on health and disease","volume":"27","author":"Trujillo","year":"2006","journal-title":"Endocr Rev"},{"issue":"3","key":"10.1016\/j.atherosclerosis.2009.07.032_bib14","doi-asserted-by":"crossref","first-page":"e1765","DOI":"10.1371\/journal.pone.0001765","article-title":"Fetuin-A induces cytokine expression and suppresses adiponectin production","volume":"3","author":"Hennige","year":"2008","journal-title":"PLoS ONE"},{"issue":"July\u2013September (3)","key":"10.1016\/j.atherosclerosis.2009.07.032_bib15","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1177\/039463200601900320","article-title":"Immunoinflammatory activation during the acute phase of lacunar and non-lacunar ischemic stroke: association with time of onset and diabetic state","volume":"19","author":"Licata","year":"2006","journal-title":"Int J Immunopathol Pharmacol"},{"issue":"5","key":"10.1016\/j.atherosclerosis.2009.07.032_bib16","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1160\/TH08-06-0375","article-title":"Immuno-inflammatory activation in acute cardio-embolic strokes in comparison with other subtypes of ischaemic stroke","volume":"101","author":"Licata","year":"2009","journal-title":"Thromb Haemost"},{"issue":"10","key":"10.1016\/j.atherosclerosis.2009.07.032_bib17","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1042\/CS20080372","article-title":"Immuno-inflammatory predictors of stroke at follow-up in patients with chronic non-valvular atrial fibrillation (NVAF)","volume":"116","author":"Pinto","year":"2009","journal-title":"Clin Sci"},{"key":"10.1016\/j.atherosclerosis.2009.07.032_bib18","first-page":"358","article-title":"Classification of subtype of acute ischemic stroke","volume":"e24","author":"Adams","year":"1993","journal-title":"Stroke"},{"key":"10.1016\/j.atherosclerosis.2009.07.032_bib19","doi-asserted-by":"crossref","first-page":"2068","DOI":"10.1161\/01.CIR.0000070585.48035.D1","article-title":"Is there a vulnerable plaque?","volume":"107","author":"Maseri","year":"2003","journal-title":"Circulation"},{"issue":"19","key":"10.1016\/j.atherosclerosis.2009.07.032_bib20","doi-asserted-by":"crossref","first-page":"2533","DOI":"10.1161\/CIRCULATIONAHA.106.682450","article-title":"Association of fetuin-A with mitral annular calcification and aortic stenosis among persons with coronary heart disease: data from the Heart and Soul Study","volume":"115","author":"Ix","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.atherosclerosis.2009.07.032_bib21","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1161\/01.ATV.0000122853.99978.b1","article-title":"CD154\/CD40-mediated expression of CD154 in endothelial cells: consequences for endothelial cell-monocyte interaction","volume":"24","author":"Wagner","year":"2004","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.atherosclerosis.2009.07.032_bib22","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1111\/j.1750-3639.2000.tb00247.x","article-title":"Inflammation and stroke: putative role for cytokines, adhesion molecules and i-NOS in brain response to ischemia","volume":"10","author":"Del Zoppo","year":"2000","journal-title":"Brain Pathol"},{"key":"10.1016\/j.atherosclerosis.2009.07.032_bib23","first-page":"20","article-title":"Cerebral protection in homozygous null ICAM-1 after middle cerebral artery occlusion: role of neutrophil adhesion in the pathogenesis of stroke","volume":"7","author":"Conolly","year":"1996","journal-title":"J Clin Invest"},{"issue":"24","key":"10.1016\/j.atherosclerosis.2009.07.032_bib24","doi-asserted-by":"crossref","first-page":"2555","DOI":"10.1161\/CIRCULATIONAHA.108.814418","article-title":"Plasma fetuin-a levels and the risk of myocardial infarction and ischemic stroke","volume":"118","author":"Weikert","year":"2008","journal-title":"Circulation"},{"issue":"June (6)","key":"10.1016\/j.atherosclerosis.2009.07.032_bib25","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1038\/sj.jhh.1002008","article-title":"Intraindividual temporal variance of biomarkers and the definition of individualized prognosis in cardiovascular patients","volume":"20","author":"MacFadyen","year":"2006","journal-title":"J Hum Hypertens"},{"issue":"3","key":"10.1016\/j.atherosclerosis.2009.07.032_bib26","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.ahj.2004.01.026","article-title":"Prognostic significance of raised plasma levels of interleukin-6 and C-reactive protein in atrial fibrillation","volume":"148","author":"Conway","year":"2004","journal-title":"Am Heart J"},{"issue":"11","key":"10.1016\/j.atherosclerosis.2009.07.032_bib27","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1046\/j.1365-2362.2003.01252.x","article-title":"Prognostic value of interleukin-6, plasma viscosity, fibrinogen, von Willebrand factor, tissue factor and vascular endothelial growth factor levels in congestive heart failure","volume":"33","author":"Chin","year":"2003","journal-title":"Eur J Clin Invest"}],"container-title":["Atherosclerosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021915009005966?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021915009005966?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,21]],"date-time":"2019-05-21T17:21:04Z","timestamp":1558459264000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021915009005966"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,1]]}},"alternative-id":["S0021915009005966"],"URL":"https:\/\/doi.org\/10.1016\/j.atherosclerosis.2009.07.032","relation":{},"ISSN":["0021-9150"],"issn-type":[{"value":"0021-9150","type":"print"}],"subject":[],"published":{"date-parts":[[2010,1]]}}}