{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T08:12:47Z","timestamp":1790496767104,"version":"4.1.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["20590835"],"award-info":[{"award-number":["20590835"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["atherosclerosis-journal.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Atherosclerosis"],"published-print":{"date-parts":[[2010,10]]},"DOI":"10.1016\/j.atherosclerosis.2010.06.025","type":"journal-article","created":{"date-parts":[[2010,6,20]],"date-time":"2010-06-20T20:24:51Z","timestamp":1277065491000},"page":"628-635","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":72,"title":["Association of monocyte subset counts with coronary fibrous cap thickness in patients with unstable angina pectoris"],"prefix":"10.1016","volume":"212","author":[{"given":"Toshio","family":"Imanishi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideyuki","family":"Ikejima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroto","family":"Tsujioka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akio","family":"Kuroi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kohei","family":"Ishibashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenichi","family":"Komukai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Tanimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasushi","family":"Ino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuya","family":"Takeshita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Akasaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib1","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/S0140-6736(05)67221-2","article-title":"BASKET investigators. Incremental cost-effectiveness of drug-eluting stents compared with a third-generation bare metal stent in a real-world setting: randomized Basel Stent Effektivitats Trial (BASKET)","volume":"366","author":"Kaiser","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib2","doi-asserted-by":"crossref","first-page":"8264","DOI":"10.1073\/pnas.92.18.8264","article-title":"Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein E","volume":"92","author":"Smith","year":"1995","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib3","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1161\/01.RES.0000260802.75766.00","article-title":"Monocyte\/macrophage suppression in CD11b diphtheria toxin receptor transgenic mice differentially affects atherogenesis and established plaques","volume":"100","author":"Stoneman","year":"2007","journal-title":"Circ Res"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib4","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1016\/j.jacc.2005.02.054","article-title":"Which white blood cell subtypes predict increased cardiovascular risk?","volume":"45","author":"Horne","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib5","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S1074-7613(03)00174-2","article-title":"Blood monocytes consist of two principal subsets with distinct migratory properties","volume":"19","author":"Geissmann","year":"2003","journal-title":"Immunity"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib6","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1038\/nri1733","article-title":"Monocyte and macrophage heterogeneity","volume":"5","author":"Gordon","year":"2005","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib7","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1172\/JCI30992","article-title":"Macrophage heterogeneity and tissue lipids","volume":"117","author":"Gordon","year":"2007","journal-title":"J Clin Invest"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib8","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1126\/science.1142883","article-title":"Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior","volume":"317","author":"Auffray","year":"2007","journal-title":"Science"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib9","first-page":"e1","article-title":"Measurement of the thickness of the fibrous cap by optical coherence tomography","volume":"755","author":"Kume","year":"2006","journal-title":"Am Heart J"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib10","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/j.jacc.2007.04.082","article-title":"Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy","volume":"50","author":"Kubo","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib11","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1253\/circj.CJ-09-0484","article-title":"Upregulation of fractalkine and its receptor. CX3CR1, is associated with coronary plaque rupture in patients with unstable angina pectoris","volume":"74","author":"Ikejima","year":"2010","journal-title":"Circ J"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib12","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/S0735-1097(01)01799-5","article-title":"Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound","volume":"39","author":"Jang","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib13","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1161\/01.CIR.0000029927.92825.F6","article-title":"Characterization of human atherosclerosis by optical coherence tomography","volume":"106","author":"Yabushita","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib14","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.jacc.2009.04.021","article-title":"Impact of heterogeneity of human peripheral blood monocyte subsets on myocardial salvage in patients with primary acute myocardial infarction","volume":"54","author":"Tsujioka","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib15","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1189\/jlb.0806510","article-title":"The CD14+CD16+ blood monocytes: their role in infection and inflammation","volume":"81","author":"Ziegler-Heitbrock","year":"2007","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib16","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1172\/JCI29950","article-title":"Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheroma","volume":"117","author":"Swirski","year":"2007","journal-title":"J Clin Invest"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib17","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1160\/TH04-02-0095","article-title":"CD14+CD16+ monocytes in coronary artery disease and their relationship to serum TNF-alpha levels","volume":"92","author":"Schlitt","year":"2004","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib18","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1161\/01.ATV.16.12.1437","article-title":"Peripheral blood mononuclear phagocyte subpopulations as cellular markers in hypercholesterolemia","volume":"16","author":"Roethe","year":"1996","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib19","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1182\/blood.V97.7.1925","article-title":"Polymorphism in the fractalkine receptor CX3CR1 as a genetic risk factor for coronary artery disease","volume":"97","author":"Moatti","year":"2001","journal-title":"Blood"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib20","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1161\/hh1701.095642","article-title":"Association between polymorphism in the chemokine receptor CX3CR1 and coronary vascular endothelial dysfunction and atherosclerosis","volume":"89","author":"MacDermott","year":"2001","journal-title":"Circ Res"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib21","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1038\/nri2528","article-title":"Trophic macrophages in development and diseases","volume":"9","author":"Pollard","year":"2009","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib22","doi-asserted-by":"crossref","first-page":"453","DOI":"10.2741\/2692","article-title":"Macrophage activation and polarization","volume":"13","author":"Martinez","year":"2008","journal-title":"Front Biosci"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib23","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1146\/annurev.immunol.021908.132557","article-title":"Blood monocytes: development, heterogeneity, and relationship with dendric cells","volume":"27","author":"Auffray","year":"2009","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib24","doi-asserted-by":"crossref","first-page":"2527","DOI":"10.1182\/blood.V74.7.2527.2527","article-title":"Identification and characterization of a novel monocyte subpopulation in human peripheral blood","volume":"74","author":"Passlick","year":"1989","journal-title":"Blood"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib25","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1038\/nature01323","article-title":"Inflammation in atherosclerosis","volume":"420","author":"Libby","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib26","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.2174\/138945007783220650","article-title":"Leukocyte influx in atherosclerosis","volume":"8","author":"Galkina","year":"2007","journal-title":"Curr Drug Targets"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib27","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1146\/annurev.immunol.021908.132620","article-title":"Immune and inflammatory mechanisms of atherosclerosis","volume":"27","author":"Galkina","year":"2009","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib28","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1161\/01.RES.83.5.490","article-title":"3-Hydroxy-3-methylglutaryl coenzyme a reductase and isoprenylation inhibitors induce apoptosis of vascular smooth muscle cells in culture","volume":"83","author":"Guijarro","year":"1998","journal-title":"Circ Res"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib29","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1046\/j.1440-1681.2003.03829.x","article-title":"Oxidized low-density lipoprotein sensitizes human vascular smooth muscle cells to FAS (CD95)-mediated apoptosis","volume":"30","author":"Takarada","year":"2003","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib30","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1161\/01.ATV.0000201073.45862.8b","article-title":"Pravastatin inhibits expression of lectin-like oxidized low-density lipoprotein receptor-1 in Watanabe heritable hyperlipidemic rabbits","volume":"26","author":"Hofnagel","year":"2006","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib31","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.atherosclerosis.2008.05.014","article-title":"Effect of statin therapy on coronary fibrous-cap thickness in patients with acute coronary syndrome: assessment by optical coherence tomography study","volume":"202","author":"Takarada","year":"2009","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib32","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1056\/NEJMoa0807646","article-title":"Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein","volume":"359","author":"Ridker","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1016\/j.atherosclerosis.2010.06.025_bib33","first-page":"202","article-title":"Advantage of next generation frequency-domain optical coherence tomography compared with assessment of coronary lesion","volume":"75","author":"Takarada","year":"2010","journal-title":"Catheter Cardiovasc Interv"}],"container-title":["Atherosclerosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021915010004430?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021915010004430?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T00:32:28Z","timestamp":1758155548000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021915010004430"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10]]},"references-count":33,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,10]]}},"alternative-id":["S0021915010004430"],"URL":"https:\/\/doi.org\/10.1016\/j.atherosclerosis.2010.06.025","relation":{},"ISSN":["0021-9150"],"issn-type":[{"value":"0021-9150","type":"print"}],"subject":[],"published":{"date-parts":[[2010,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of monocyte subset counts with coronary fibrous cap thickness in patients with unstable angina pectoris","name":"articletitle","label":"Article Title"},{"value":"Atherosclerosis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.atherosclerosis.2010.06.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}