{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:40:40Z","timestamp":1786984840607,"version":"build-2736575974"},"reference-count":29,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,5,1]],"date-time":"2012-05-01T00:00:00Z","timestamp":1335830400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"UCDHS Research Fund"},{"name":"Children's Miracle Network Grant"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Atherosclerosis"],"published-print":{"date-parts":[[2012,5]]},"DOI":"10.1016\/j.atherosclerosis.2012.02.005","type":"journal-article","created":{"date-parts":[[2012,2,17]],"date-time":"2012-02-17T03:52:57Z","timestamp":1329450777000},"page":"59-66","source":"Crossref","is-referenced-by-count":10,"title":["A combination of secondhand cigarette smoke and Chlamydia pneumoniae accelerates atherosclerosis"],"prefix":"10.1016","volume":"222","author":[{"given":"Xiaoyan","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"De-xiu","family":"Bu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kweku","family":"Hayfron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kent E.","family":"Pinkerton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles L.","family":"Bevins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Lichtman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Wiedeman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0005","unstructured":"U.S. Department of Health and Human Services. The health consequences of involuntary exposure to tobacco smoke: a report of the surgeon general. U.S. Department of Health and Human Services, Center for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health; 2006."},{"issue":"Suppl. 3","key":"10.1016\/j.atherosclerosis.2012.02.005_bib0010","doi-asserted-by":"crossref","first-page":"S432","DOI":"10.1086\/315615","article-title":"Detection of Chlamydia pneumoniae in arterial tissues","volume":"181","author":"Kuo","year":"2000","journal-title":"J Infect Dis"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0015","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.micpath.2005.09.001","article-title":"Tobacco smoke induces a persistent, but recoverable state in Chlamydia pneumoniae infection of human endothelial cells","volume":"39","author":"Wiedeman","year":"2005","journal-title":"Microb Pathog"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0020","doi-asserted-by":"crossref","first-page":"7176","DOI":"10.4049\/jimmunol.181.10.7176","article-title":"TLR\/MyD88 and liver X receptor alpha signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosis","volume":"181","author":"Naiki","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0025","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.4049\/jimmunol.180.2.1169","article-title":"Cigarette smoke-induced pulmonary inflammation is TLR4\/MyD88 and IL-1R1\/MyD88 signaling dependent","volume":"180","author":"Doz","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0030","doi-asserted-by":"crossref","first-page":"e1000379","DOI":"10.1371\/journal.ppat.1000379","article-title":"The NOD\/RIP2 pathway is essential for host defenses against Chlamydophila pneumoniae lung infection","volume":"5","author":"Shimada","year":"2009","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0035","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.1600-065X.2007.00554.x","article-title":"Innate immunity, macrophage activation, and atherosclerosis","volume":"219","author":"Yan","year":"2007","journal-title":"Immunol Rev"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0040","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1002\/j.1460-2075.1990.tb08211.x","article-title":"Characterization of the MRC OX40 antigen of activated CD4 positive T lymphocytes \u2013 a molecule related to nerve growth factor receptor","volume":"9","author":"Mallett","year":"1990","journal-title":"EMBO J"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0045","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1038\/ng1524","article-title":"Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility","volume":"37","author":"Wang","year":"2005","journal-title":"Nat Genet"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0050","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1007\/s10495-010-0516-6","article-title":"Mechanisms of failed apoptotic cell clearance by phagocyte subsets in cardiovascular disease","volume":"15","author":"Thorp","year":"2010","journal-title":"Apoptosis"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0055","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1093\/oxfordjournals.jbchem.a022622","article-title":"Promotion of the uptake of PS liposomes and apoptotic cells by a product of growth arrest-specific gene, gas6","volume":"127","author":"Ishimoto","year":"2000","journal-title":"J Biochem"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0060","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1038\/nri2675","article-title":"Macrophage death and defective inflammation resolution in atherosclerosis","volume":"10","author":"Tabas","year":"2010","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0065","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1161\/ATVBAHA.108.167197","article-title":"Mertk receptor mutation reduces efferocytosis efficiency and promotes apoptotic cell accumulation and plaque necrosis in atherosclerotic lesions of ApoE\u2212\/\u2212 mice","volume":"28","author":"Thorp","year":"2008","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0070","doi-asserted-by":"crossref","first-page":"416","DOI":"10.2353\/ajpath.2007.060406","article-title":"Complement C1q reduces early atherosclerosis in low-density lipoprotein receptor-deficient mice","volume":"170","author":"Bhatia","year":"2007","journal-title":"Am J Pathol"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0075","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1161\/01.ATV.0000203503.82693.c1","article-title":"Leukocyte transglutaminase 2 expression limits atherosclerotic lesion size","volume":"26","author":"Boisvert","year":"2006","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0080","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1084\/jem.20031557","article-title":"Impaired clearance of apoptotic cells promotes synergy between atherogenesis and autoimmune disease","volume":"199","author":"Aprahamian","year":"2004","journal-title":"J Exp Med"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0085","doi-asserted-by":"crossref","first-page":"3715","DOI":"10.1161\/01.CIR.0000149747.82157.01","article-title":"Prenatal environmental tobacco smoke exposure promotes adult atherogenesis and mitochondrial damage in Apolipoprotein E\u2212\/\u2212 mice fed a chow diet","volume":"110","author":"Yang","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0090","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1086\/320735","article-title":"Infection of mice with the agent of human granulocytic ehrlichiosis after different routes of inoculation","volume":"183","author":"Hodzic","year":"2001","journal-title":"J Infect Dis"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0095","doi-asserted-by":"crossref","first-page":"2974","DOI":"10.1172\/JCI31344","article-title":"Proatherogenic immune responses are regulated by the PD-1\/PD-L pathway in mice","volume":"117","author":"Gotsman","year":"2007","journal-title":"J Clin Invest"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0100","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1161\/ATVBAHA.111.224709","article-title":"Impairment of the programmed cell death-1 pathway increases atherosclerotic lesion development and inflammation","volume":"31","author":"Bu","year":"2011","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0105","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1056\/NEJMra043430","article-title":"Inflammation, atherosclerosis, and coronary artery disease","volume":"352","author":"Hansson","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0110","doi-asserted-by":"crossref","first-page":"2684","DOI":"10.1161\/CIRCULATIONAHA.104.492215","article-title":"Cardiovascular effects of secondhand smoke: nearly as large as smoking","volume":"111","author":"Barnoya","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0115","doi-asserted-by":"crossref","first-page":"328","DOI":"10.2174\/1871528110908050328","article-title":"The causal relationship between passive smoking and inflammation on the development of cardiovascular disease: a review of the evidence","volume":"8","author":"Vardavas","year":"2009","journal-title":"Inflamm Allergy Drug Targets"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0120","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1093\/cvr\/cvn120","article-title":"Cytokines and atherosclerosis: a comprehensive review of studies in mice","volume":"79","author":"Kleemann","year":"2008","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0125","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.atherosclerosis.2004.06.018","article-title":"IL-6 and the acute phase response in murine atherosclerosis","volume":"177","author":"Song","year":"2004","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0130","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1038\/nri803","article-title":"Effects of cigarette smoke on the immune system","volume":"2","author":"Sopori","year":"2002","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0135","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1084\/jem.191.2.365","article-title":"Impairment of antigen-presenting cell function in mice lacking expression of OX40 ligand","volume":"191","author":"Murata","year":"2000","journal-title":"J Exp Med"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0140","doi-asserted-by":"crossref","first-page":"3838","DOI":"10.4049\/jimmunol.159.8.3838","article-title":"Expression and function of OX40 ligand on human dendritic cells","volume":"159","author":"Ohshima","year":"1997","journal-title":"J Immunol"},{"key":"10.1016\/j.atherosclerosis.2012.02.005_bib0145","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/S1074-7613(01)00191-1","article-title":"OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells","volume":"15","author":"Rogers","year":"2001","journal-title":"Immunity"}],"container-title":["Atherosclerosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021915012001177?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021915012001177?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,6,14]],"date-time":"2023-06-14T16:02:43Z","timestamp":1686758563000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021915012001177"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,5]]}},"alternative-id":["S0021915012001177"],"URL":"https:\/\/doi.org\/10.1016\/j.atherosclerosis.2012.02.005","relation":{},"ISSN":["0021-9150"],"issn-type":[{"value":"0021-9150","type":"print"}],"subject":[],"published":{"date-parts":[[2012,5]]}}}