{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T21:08:31Z","timestamp":1792012111304,"version":"4.4.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Atherosclerosis"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1016\/j.atherosclerosis.2012.11.001","type":"journal-article","created":{"date-parts":[[2012,11,15]],"date-time":"2012-11-15T10:28:39Z","timestamp":1352975319000},"page":"134-139","source":"Crossref","is-referenced-by-count":37,"title":["Epicardial adipose tissue thickness is a predictor for plaque vulnerability in\u00a0patients with significant coronary artery disease"],"prefix":"10.1016","volume":"226","author":[{"given":"Jin-Sun","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"So-Yeon","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingri","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyoung-Mo","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Seok","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byoung-Joo","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myeong-Ho","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gyo-Seung","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung-Jea","family":"Tahk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joon-Han","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.atherosclerosis.2012.11.001_bib1","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1038\/ncpcardio0319","article-title":"Epicardial adipose tissue: anatomic, biomolecular and clinical relationships with the heart","volume":"2","author":"Iacobellis","year":"2005","journal-title":"Nat Clin Pract Cardiovasc Med"},{"key":"10.1016\/j.atherosclerosis.2012.11.001_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1475-2840-5-1","article-title":"Human epicardial adipose tissue expresses a pathogenic profile of adipocytokines in patients with cardiovascular disease","volume":"5","author":"Baker","year":"2006","journal-title":"Cardiovasc Diabetol"},{"key":"10.1016\/j.atherosclerosis.2012.11.001_bib3","doi-asserted-by":"crossref","first-page":"e7","DOI":"10.1136\/hrt.2007.118471","article-title":"Relationship of epicardial adipose tissue by echocardiography to coronary artery disease","volume":"94","author":"Ahn","year":"2008","journal-title":"Heart"},{"issue":"3","key":"10.1016\/j.atherosclerosis.2012.11.001_bib4","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.numecd.2008.05.002","article-title":"Epicardial adipose tissue thickness by echocardiography is a marker for the presence and severity of coronary artery disease","volume":"19","author":"Eroglu","year":"2009","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"10.1016\/j.atherosclerosis.2012.11.001_bib5","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.1016\/j.amjcard.2008.08.010","article-title":"Relation of epicardial adipose tissue to coronary atherosclerosis","volume":"102","author":"Djaberi","year":"2008","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.atherosclerosis.2012.11.001_bib6","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.amjcard.2008.04.002","article-title":"Relation of epicardial and pericardial fat to coronary atherosclerosis and coronary artery calcium in patients undergoing coronary angiography","volume":"102","author":"Gorter","year":"2008","journal-title":"Am J Cardiol"},{"issue":"4","key":"10.1016\/j.atherosclerosis.2012.11.001_bib7","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1136\/hrt.76.4.312","article-title":"Clinically stable angina pectoris is not necessarily associated with histologically stable atherosclerotic plaques","volume":"76","author":"van der Wal","year":"1996","journal-title":"Heart"},{"issue":"9","key":"10.1016\/j.atherosclerosis.2012.11.001_bib8","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/BF03091809","article-title":"Thrombus aspiration in a series of patients with stable or unstable angina pectoris and lesion-site thrombus formation","volume":"18","author":"Hermens","year":"2010","journal-title":"Neth Heart J"},{"issue":"3","key":"10.1016\/j.atherosclerosis.2012.11.001_bib9","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1136\/heart.83.3.346","article-title":"Increased serum neopterin: a marker of coronary artery disease activity in women","volume":"83","author":"Garcia-Moll","year":"2000","journal-title":"Heart"},{"issue":"3","key":"10.1016\/j.atherosclerosis.2012.11.001_bib10","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1136\/hrt.82.3.269","article-title":"Plaque erosion is a major substrate for coronary thrombosis in acute myocardial infarction","volume":"82","author":"Arbustini","year":"1999","journal-title":"Heart"},{"issue":"13","key":"10.1016\/j.atherosclerosis.2012.11.001_bib11","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.1097\/QAD.0b013e32833c055a","article-title":"Increased epicardial adipose tissue volume in HIV-infected men and relationships to body composition and metabolic parameters","volume":"24","author":"Lo","year":"2010","journal-title":"AIDS"},{"issue":"2","key":"10.1016\/j.atherosclerosis.2012.11.001_bib12","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/0002-9343(75)90575-6","article-title":"The heart in systemic lupus erythematosus and the changes induced in it by corticosteroid therapy. A study of 36 necropsy patients","volume":"58","author":"Bulkley","year":"1975","journal-title":"Am J Med"},{"issue":"22","key":"10.1016\/j.atherosclerosis.2012.11.001_bib13","doi-asserted-by":"crossref","first-page":"2634","DOI":"10.1161\/CIRCULATIONAHA.107.187397","article-title":"Universal definition of myocardial infarction","volume":"116","author":"Thygesen","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.atherosclerosis.2012.11.001_bib14","doi-asserted-by":"crossref","first-page":"2200","DOI":"10.1161\/01.CIR.0000035654.18341.5E","article-title":"Coronary plaque classification with intravascular ultrasound radiofrequency data analysis","volume":"106","author":"Nair","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.atherosclerosis.2012.11.001_bib15","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.1016\/j.jacc.2006.02.044","article-title":"Accuracy of in\u00a0vivo coronary plaque morphology assessment: a validation study of in\u00a0vivo virtual histology compared with in\u00a0vitro histopathology","volume":"47","author":"Nasu","year":"2006","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.atherosclerosis.2012.11.001_bib16","doi-asserted-by":"crossref","first-page":"2038","DOI":"10.1016\/j.jacc.2005.07.064","article-title":"In\u00a0vivo intravascular ultrasound-derived thin-cap fibroatheroma detection using ultrasound radiofrequency data analysis","volume":"46","author":"Rodriguez-Granillo","year":"2005","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.atherosclerosis.2012.11.001_bib17","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/1475-2840-9-29","article-title":"Impact of body mass index on the relationship of epicardial adipose tissue to metabolic syndrome and coronary artery disease in an Asian population","volume":"9","author":"Park","year":"2010","journal-title":"Cardiovasc Diabetol"},{"issue":"1","key":"10.1016\/j.atherosclerosis.2012.11.001_bib18","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.atherosclerosis.2009.11.020","article-title":"Epicardial adipose tissue and coronary artery plaque characteristics","volume":"210","author":"Alexopoulos","year":"2010","journal-title":"Atherosclerosis"},{"issue":"3","key":"10.1016\/j.atherosclerosis.2012.11.001_bib19","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s10554-007-9262-4","article-title":"Quantification of atherosclerotic coronary plaque components by submillimeter computed tomography","volume":"24","author":"Knollmann","year":"2008","journal-title":"Int J Cardiovasc Imaging"},{"issue":"8","key":"10.1016\/j.atherosclerosis.2012.11.001_bib20","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1016\/j.amjcard.2008.05.060","article-title":"Comparison of 64-slice multidetector computed tomography with spectral analysis of intravascular ultrasound backscatter signals for characterizations of noncalcified coronary arterial plaques","volume":"102","author":"Choi","year":"2008","journal-title":"Am J Cardiol"},{"issue":"1","key":"10.1016\/j.atherosclerosis.2012.11.001_bib21","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.atherosclerosis.2010.02.013","article-title":"Association of pericoronary fat volume with atherosclerotic plaque burden in the underlying coronary artery: a segment analysis","volume":"211","author":"Mahabadi","year":"2010","journal-title":"Atherosclerosis"},{"issue":"4","key":"10.1016\/j.atherosclerosis.2012.11.001_bib22","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/S0195-668X(02)00426-8","article-title":"Eccentric atherosclerotic plaques with positive remodeling have a pericardial distribution: a permissive role of epicardial fat?","volume":"24","author":"Prati","year":"2003","journal-title":"Eur Heart J"},{"key":"10.1016\/j.atherosclerosis.2012.11.001_bib23","doi-asserted-by":"crossref","first-page":"2460","DOI":"10.1161\/01.CIR.0000099542.57313.C5","article-title":"Human epicardial adipose tissue is a source of inflammatory mediators","volume":"108","author":"Mazurek","year":"2003","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.atherosclerosis.2012.11.001_bib24","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.jcin.2010.12.015","article-title":"The relationship between volumetric plaque components and classical cardiovascular risk factors and the metabolic syndrome a 3-vessel coronary artery virtual histology-intravascular ultrasound analysis","volume":"4","author":"Zheng","year":"2011","journal-title":"JACC Cardiovasc Interv"},{"issue":"1","key":"10.1016\/j.atherosclerosis.2012.11.001_bib25","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s10557-008-6147-2","article-title":"Inflammation and plaque vulnerability","volume":"23","author":"Shah","year":"2009","journal-title":"Cardiovasc Drugs Ther"},{"issue":"7","key":"10.1016\/j.atherosclerosis.2012.11.001_bib26","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1016\/0735-1097(94)90657-2","article-title":"Characterization of the relative thrombogenicity of atherosclerotic plaque components: implications for consequences of plaque rupture","volume":"23","author":"Fern\u00e1ndez-Ortiz","year":"1994","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"Suppl. 2","key":"10.1016\/j.atherosclerosis.2012.11.001_bib27","first-page":"49","article-title":"Coronary calcification: insights from sudden coronary death victims","volume":"89","author":"Burke","year":"2000","journal-title":"Z\u00a0Kardiol"},{"issue":"5","key":"10.1016\/j.atherosclerosis.2012.11.001_bib28","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1161\/01.ATV.20.5.1262","article-title":"Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesion","volume":"20","author":"Virmani","year":"2000","journal-title":"Atheroscler Thromb Vasc Biol"},{"issue":"47","key":"10.1016\/j.atherosclerosis.2012.11.001_bib29","doi-asserted-by":"crossref","first-page":"C13","DOI":"10.1016\/j.jacc.2005.10.065","article-title":"Pathology of the vulnerable plaque","volume":"18","author":"Virmani","year":"2006","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"1","key":"10.1016\/j.atherosclerosis.2012.11.001_bib30","doi-asserted-by":"crossref","first-page":"17","DOI":"10.4250\/jcu.2008.16.1.17","article-title":"Echocardiographic plains reflecting total amount of epicardial adipose tissue as risk factor of coronary artery disease","volume":"16","author":"Hwang","year":"2008","journal-title":"J\u00a0Cardiovasc Ultrasound"},{"issue":"11","key":"10.1016\/j.atherosclerosis.2012.11.001_bib31","doi-asserted-by":"crossref","first-page":"5163","DOI":"10.1210\/jc.2003-030698","article-title":"Echocardiographic epicardial adipose tissue is related to anthropometric and clinical parameters of metabolic syndrome: a new indicator of cardiovascular risk","volume":"88","author":"Iacobellis","year":"2003","journal-title":"J\u00a0Clin Endocrinol Metab"},{"issue":"4","key":"10.1016\/j.atherosclerosis.2012.11.001_bib32","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1161\/CIRCIMAGING.109.919357","article-title":"Unreliable assessment of necrotic core by virtual histology intravascular ultrasound in porcine coronary artery disease","volume":"3","author":"Thim","year":"2010","journal-title":"Circ Cardiovasc Imaging"},{"issue":"1","key":"10.1016\/j.atherosclerosis.2012.11.001_bib33","first-page":"113","article-title":"Automated coronary plaque characterisation with intravascular ultrasound backscatter: ex\u00a0vivo validation","volume":"3","author":"Nair","year":"2007","journal-title":"EuroIntervention"},{"issue":"8","key":"10.1016\/j.atherosclerosis.2012.11.001_bib34","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1016\/j.jcmg.2011.05.005","article-title":"Association between IVUS findings and adverse outcomes in patients with coronary artery disease: the VIVA (VH-IVUS in Vulnerable Atherosclerosis) Study","volume":"4","author":"Calvert","year":"2011","journal-title":"JACC Cardiovasc Imaging"}],"container-title":["Atherosclerosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021915012007964?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021915012007964?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,21]],"date-time":"2018-10-21T10:29:27Z","timestamp":1540117767000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021915012007964"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["S0021915012007964"],"URL":"https:\/\/doi.org\/10.1016\/j.atherosclerosis.2012.11.001","relation":{},"ISSN":["0021-9150"],"issn-type":[{"value":"0021-9150","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]}}}