{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:40:41Z","timestamp":1786984841588,"version":"build-2736575974"},"reference-count":52,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"CIHR China\u2013Canada"},{"name":"Heart and Stroke Foundation of Canada"}],"content-domain":{"domain":["atherosclerosis-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Atherosclerosis"],"published-print":{"date-parts":[[2013,5]]},"DOI":"10.1016\/j.atherosclerosis.2013.01.041","type":"journal-article","created":{"date-parts":[[2013,2,9]],"date-time":"2013-02-09T20:53:23Z","timestamp":1360443203000},"page":"98-109","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":63,"title":["Inhibition of sphingolipid synthesis improves dyslipidemia in the diet-induced hamster model of insulin resistance: Evidence for the role of\u00a0sphingosine and sphinganine in hepatic VLDL-apoB100 overproduction"],"prefix":"10.1016","volume":"228","author":[{"given":"Mark J.","family":"Dekker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Baker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Naples","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josh","family":"Samsoondar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rianna","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Sacco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khosrow","family":"Adeli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib1","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1161\/ATVBAHA.107.160192","article-title":"Overproduction of very low-density lipoproteins is the hallmark of the dyslipidemia in the metabolic syndrome","volume":"28","author":"Adiels","year":"2008","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib2","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.jnutbio.2010.11.013","article-title":"Redox homeostasis and posttranslational modifications\/activity of phosphatase and tensin homolog in hepatocytes from rats with diet-induced hepatosteatosis","volume":"23","author":"Alisi","year":"2012","journal-title":"J Nutr Biochem"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib3","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/S0022-2275(20)41509-3","article-title":"Inhibition of fatty acid synthesis decreases very low density lipoprotein secretion in the hamster","volume":"33","author":"Arbeeny","year":"1992","journal-title":"J\u00a0Lipid Res"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib4","doi-asserted-by":"crossref","first-page":"G323","DOI":"10.1152\/ajpgi.90546.2008","article-title":"LXRalpha activation perturbs hepatic insulin signaling and stimulates production of apolipoprotein B-containing lipoproteins","volume":"297","author":"Basciano","year":"2009","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib5","doi-asserted-by":"crossref","first-page":"E462","DOI":"10.1152\/ajpendo.90764.2008","article-title":"Metabolic effects of dietary cholesterol in an animal model of insulin resistance and hepatic steatosis","volume":"297","author":"Basciano","year":"2009","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib6","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1002\/hep.23175","article-title":"Modulation of glycosphingolipid metabolism significantly improves hepatic insulin sensitivity and reverses hepatic steatosis in mice","volume":"50","author":"Bijl","year":"2009","journal-title":"Hepatology"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib7","doi-asserted-by":"crossref","first-page":"20148","DOI":"10.1074\/jbc.M412769200","article-title":"Acid ceramidase overexpression prevents the inhibitory effects of saturated fatty acids on insulin signaling","volume":"280","author":"Chavez","year":"2005","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib8","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.diabres.2011.03.017","article-title":"Inhibition of ceramide synthesis reverses endothelial dysfunction and atherosclerosis in streptozotocin-induced diabetic rats","volume":"93","author":"Chun","year":"2011","journal-title":"Diabetes Res Clin Pract"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib9","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0021-9258(18)64849-5","article-title":"A\u00a0simple method for the isolation and purification of total lipides from animal tissues","volume":"226","author":"Folch","year":"1957","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib10","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.arcmed.2005.01.005","article-title":"Regulation of plasma triglycerides in insulin resistance and diabetes","volume":"36","author":"Ginsberg","year":"2005","journal-title":"Arch Med Res"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib11","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1042\/CS20090452","article-title":"Myriocin-mediated up-regulation of hepatocyte apoA-I synthesis is associated with ERK inhibition","volume":"118","author":"Glaros","year":"2010","journal-title":"Clin Sci"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib12","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1194\/jlr.M700261-JLR200","article-title":"Myriocin slows the progression of established atherosclerotic lesions in apolipoprotein E gene knockout mice","volume":"49","author":"Glaros","year":"2008","journal-title":"J\u00a0Lipid Res"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib13","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1016\/j.bcp.2006.12.023","article-title":"Inhibition of atherosclerosis by the serine palmitoyl transferase inhibitor myriocin is associated with reduced plasma glycosphingolipid concentration","volume":"73","author":"Glaros","year":"2007","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib14","doi-asserted-by":"crossref","first-page":"5755","DOI":"10.1210\/jcem.86.12.8075","article-title":"Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletes","volume":"86","author":"Goodpaster","year":"2001","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib15","doi-asserted-by":"crossref","first-page":"337","DOI":"10.2337\/db08-1228","article-title":"Plasma ceramides are elevated in obese subjects with type 2 diabetes and correlate with the severity of insulin resistance","volume":"58","author":"Haus","year":"2009","journal-title":"Diabetes"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib16","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1023\/B:MYCO.0000024182.04140.95","article-title":"Inhibition of serine palmitoyltransferase by myriocin, a natural mycotoxin, causes induction of c-myc in mouse liver","volume":"157","author":"He","year":"2004","journal-title":"Mycopathologia"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib17","doi-asserted-by":"crossref","first-page":"10284","DOI":"10.1074\/jbc.M412348200","article-title":"Effect of myriocin on plasma sphingolipid metabolism and atherosclerosis in apoE-deficient mice","volume":"280","author":"Hojjati","year":"2005","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib18","doi-asserted-by":"crossref","first-page":"1858","DOI":"10.1172\/JCI43378","article-title":"Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice","volume":"121","author":"Holland","year":"2011","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib19","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.cmet.2007.01.002","article-title":"Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance","volume":"5","author":"Holland","year":"2007","journal-title":"Cell Metab"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib20","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1210\/er.2007-0025","article-title":"Sphingolipids, insulin resistance, and metabolic disease: new insights from in\u00a0vivo manipulation of sphingolipid metabolism","volume":"29","author":"Holland","year":"2008","journal-title":"Endocr Rev"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib21","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1126\/science.7678183","article-title":"Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance","volume":"259","author":"Hotamisligil","year":"1993","journal-title":"Science"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib22","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/j.nut.2007.04.014","article-title":"Effect of dietary cholesterol and high fat on ceramide concentration in rat tissues","volume":"23","author":"Ichi","year":"2007","journal-title":"Nutrition"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib23","doi-asserted-by":"crossref","first-page":"2614","DOI":"10.1161\/01.ATV.20.12.2614","article-title":"Plasma sphingomyelin level as a risk factor for coronary artery disease","volume":"20","author":"Jiang","year":"2000","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib24","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1152\/japplphysiol.01438.2005","article-title":"Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: role of intramuscular accumulation of lipid metabolites","volume":"100","author":"Lee","year":"2006","journal-title":"J\u00a0Appl Physiol"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib25","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib26","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0300-9629(91)90263-C","article-title":"The association of hepatic apoprotein and lipid metabolism in hamsters and rats","volume":"99","author":"Liu","year":"1991","journal-title":"Comp Biochem Physiol A Comp Physiol"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib27","doi-asserted-by":"crossref","first-page":"13834","DOI":"10.1074\/jbc.270.23.13834","article-title":"Sphingolipid biosynthesis de novo by rat hepatocytes in culture. Ceramide and sphingomyelin are associated with, but not required for, very low density lipoprotein secretion","volume":"270","author":"Merrill","year":"1995","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib28","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1006\/bbrc.1995.1827","article-title":"Serine palmitoyltransferase is the primary target of a sphingosine-like immunosuppressant, ISP-1\/myriocin","volume":"211","author":"Miyake","year":"1995","journal-title":"Biochem Biophys Res Commun"},{"issue":"Suppl.","key":"10.1016\/j.atherosclerosis.2013.01.041_bib29","doi-asserted-by":"crossref","first-page":"S74","DOI":"10.1194\/jlr.R800053-JLR200","article-title":"Hepatic triacylglycerol accumulation and insulin resistance","volume":"50","author":"Nagle","year":"2009","journal-title":"J\u00a0Lipid Res"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib30","doi-asserted-by":"crossref","first-page":"3143","DOI":"10.1161\/circ.106.25.3143","article-title":"Third report of the National Cholesterol Education Program (NCEP) Expert Panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) final report","volume":"106","author":"NCEP","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib31","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/0006-291X(86)90303-7","article-title":"Sphingolipids inhibit insulin and phorbol ester stimulated uptake of 2-deoxyglucose","volume":"138","author":"Nelson","year":"1986","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib32","doi-asserted-by":"crossref","first-page":"3465","DOI":"10.1161\/01.CIR.0000148370.60535.22","article-title":"Inhibition of sphingomyelin synthesis reduces atherogenesis in apolipoprotein E-knockout mice","volume":"110","author":"Park","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib33","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.atherosclerosis.2005.12.029","article-title":"Modulation of lipoprotein metabolism by inhibition of sphingomyelin synthesis in ApoE knockout mice","volume":"189","author":"Park","year":"2006","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib34","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.phrs.2008.06.005","article-title":"Serine palmitoyltransferase inhibitor myriocin induces the regression of atherosclerotic plaques in hyperlipidemic ApoE-deficient mice","volume":"58","author":"Park","year":"2008","journal-title":"Pharmacol Res"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib35","doi-asserted-by":"crossref","first-page":"12583","DOI":"10.1074\/jbc.M611157200","article-title":"Key role for ceramides in mediating insulin resistance in human muscle cells","volume":"282","author":"Pickersgill","year":"2007","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib36","doi-asserted-by":"crossref","first-page":"G1120","DOI":"10.1152\/ajpgi.00407.2007","article-title":"Tumor necrosis factor-alpha directly stimulates the overproduction of hepatic apolipoprotein B100-containing VLDL via impairment of hepatic insulin signaling","volume":"294","author":"Qin","year":"2008","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib37","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/j.jnutbio.2008.08.005","article-title":"Cinnamon extract inhibits the postprandial overproduction of apolipoprotein B48-containing lipoproteins in fructose-fed animals","volume":"20","author":"Qin","year":"2009","journal-title":"J\u00a0Nutr Biochem"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib38","doi-asserted-by":"crossref","first-page":"3555","DOI":"10.1016\/S0021-9258(18)53730-3","article-title":"Assembly of rat hepatic very low density lipoproteins in the endoplasmic reticulum","volume":"268","author":"Rusi\u00f1ol","year":"1993","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib39","doi-asserted-by":"crossref","first-page":"2579","DOI":"10.2337\/db06-0330","article-title":"Altered adipose and plasma sphingolipid metabolism in obesity: a potential mechanism for cardiovascular and metabolic risk","volume":"55","author":"Samad","year":"2006","journal-title":"Diabetes"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib40","doi-asserted-by":"crossref","first-page":"32345","DOI":"10.1074\/jbc.M313478200","article-title":"Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease","volume":"279","author":"Samuel","year":"2004","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib41","doi-asserted-by":"crossref","first-page":"12354","DOI":"10.1073\/pnas.94.23.12354","article-title":"Cholesterol feeding reduces nuclear forms of sterol regulatory element binding proteins in hamster liver","volume":"94","author":"Shimomura","year":"1997","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib42","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1172\/JCI37385","article-title":"Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight\/obese humans","volume":"119","author":"Stanhope","year":"2009","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib43","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1900\/RDS.2008.5.13","article-title":"The role of skeletal muscle sphingolipids in the development of insulin resistance","volume":"5","author":"Straczkowski","year":"2008","journal-title":"Rev Diabet Stud"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib44","doi-asserted-by":"crossref","first-page":"8416","DOI":"10.1074\/jbc.275.12.8416","volume":"275","author":"Taghibiglou","year":"2000","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib45","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1074\/jbc.M106737200","article-title":"Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructose-fed hamster model of insulin resistance","volume":"277","author":"Taghibiglou","year":"2002","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib46","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1152\/physrev.00019.2009","article-title":"Metabolic effects of fructose and the worldwide increase in obesity","volume":"90","author":"Tappy","year":"2010","journal-title":"Physiol Rev"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib47","doi-asserted-by":"crossref","first-page":"G1287","DOI":"10.1152\/ajpgi.90540.2008","article-title":"Inflammatory NF-kappaB activation promotes hepatic apolipoprotein B100 secretion: evidence for a link between hepatic inflammation and lipoprotein production","volume":"296","author":"Tsai","year":"2009","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib48","doi-asserted-by":"crossref","first-page":"E1341","DOI":"10.1152\/ajpendo.00095.2006","article-title":"Apoptosis in skeletal muscle myotubes is induced by ceramides and is positively related to insulin resistance","volume":"291","author":"Turpin","year":"2006","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib49","doi-asserted-by":"crossref","first-page":"2453","DOI":"10.2337\/db09-1293","article-title":"Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption","volume":"59","author":"Ussher","year":"2010","journal-title":"Diabetes"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib50","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1002\/hep.22523","article-title":"Suppressor of cytokine signaling-3 (SOCS-3) and a deficit of serine\/threonine (Ser\/Thr) phosphoproteins involved in leptin transduction mediate the effect of fructose on rat liver lipid metabolism","volume":"48","author":"Vila","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib51","doi-asserted-by":"crossref","first-page":"E211","DOI":"10.1152\/ajpendo.91014.2008","article-title":"Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome","volume":"297","author":"Yang","year":"2009","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.atherosclerosis.2013.01.041_bib52","doi-asserted-by":"crossref","first-page":"E11239","DOI":"10.1371\/journal.pone.0011239","article-title":"Increased hepatic insulin action in diet-induced obese mice following inhibition of glucosylceramide synthase","volume":"5","author":"Yew","year":"2010","journal-title":"PLoS One"}],"container-title":["Atherosclerosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021915013001032?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021915013001032?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,2,8]],"date-time":"2022-02-08T02:56:42Z","timestamp":1644289002000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021915013001032"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5]]},"references-count":52,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["S0021915013001032"],"URL":"https:\/\/doi.org\/10.1016\/j.atherosclerosis.2013.01.041","relation":{},"ISSN":["0021-9150"],"issn-type":[{"value":"0021-9150","type":"print"}],"subject":[],"published":{"date-parts":[[2013,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inhibition of sphingolipid synthesis improves dyslipidemia in the diet-induced hamster model of insulin resistance: Evidence for the role of\u00a0sphingosine and sphinganine in hepatic VLDL-apoB100 overproduction","name":"articletitle","label":"Article Title"},{"value":"Atherosclerosis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.atherosclerosis.2013.01.041","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}