{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T19:10:14Z","timestamp":1760987414794,"version":"3.44.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T00:00:00Z","timestamp":1396310400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T00:00:00Z","timestamp":1396310400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,2,2]],"date-time":"2014-02-02T00:00:00Z","timestamp":1391299200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["atherosclerosis-journal.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Atherosclerosis"],"published-print":{"date-parts":[[2014,4]]},"DOI":"10.1016\/j.atherosclerosis.2014.01.030","type":"journal-article","created":{"date-parts":[[2014,1,24]],"date-time":"2014-01-24T19:22:25Z","timestamp":1390591345000},"page":"616-622","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Soluble Fas ligand is associated with natural killer cell dynamics in coronary artery disease"],"prefix":"10.1016","volume":"233","author":[{"given":"Aleksander","family":"Szymanowski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Lundberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chamilly","family":"Evaldsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lennart","family":"Nilsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9111-7527","authenticated-orcid":false,"given":"Karin","family":"Backteman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Ernerudh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lena","family":"Jonasson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib1","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1038\/ni.2001","article-title":"The immune system in atherosclerosis","volume":"12","author":"Hansson","year":"2011","journal-title":"Nat Immunol"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib2","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1038\/nrcardio.2011.62","article-title":"Adaptive immunity in atherosclerosis: mechanisms and future therapeutic targets","volume":"8","author":"Lahoute","year":"2011","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib3","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.atherosclerosis.2005.03.011","article-title":"Loss of natural killer cell activity in patients with coronary artery disease","volume":"183","author":"Jonasson","year":"2005","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib4","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1742-4933-4-3","article-title":"NK cell compartment in patients with coronary heart disease","volume":"4","author":"Hak","year":"2007","journal-title":"Immun Ageing"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib5","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.atherosclerosis.2012.02.009","article-title":"Increased expression of T cell immunoglobulin- and mucin domain-containing molecule-3 on natural killer cells in atherogenesis","volume":"222","author":"Hou","year":"2012","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib6","doi-asserted-by":"crossref","first-page":"e32691","DOI":"10.1371\/journal.pone.0032691","article-title":"Lymphocyte subpopulations in lymph nodes and peripheral blood: a comparison between patients with stable angina and acute coronary syndrome","volume":"7","author":"Backteman","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib7","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.jim.2007.01.021","article-title":"Biological and methodological variation of lymphocyte subsets in blood of human adults","volume":"322","author":"Backteman","year":"2007","journal-title":"J\u00a0Immunol Methods"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib8","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1111\/cei.12210","article-title":"NK cell deficit in coronary artery disease: no aberrations in phenotype but sustained reduction of NK cells is associated with low-grade inflammation","volume":"175","author":"Backteman","year":"2014","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib9","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.atherosclerosis.2007.10.031","article-title":"NK cell apoptosis in coronary artery disease: relation to oxidative stress","volume":"199","author":"Li","year":"2008","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib10","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.jss.2007.07.011","article-title":"Elevated Fas expression is related to increased apoptosis of circulating CD8+ T cell in patients with gastric cancer","volume":"148","author":"Yoshikawa","year":"2008","journal-title":"J\u00a0Surg Res"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib11","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/s10120-012-0210-1","article-title":"Increased apoptosis and elevated Fas expression in circulating natural killer cells in gastric cancer patients","volume":"16","author":"Saito","year":"2013","journal-title":"Gastric Cancer"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib12","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1191\/096120399678840765","article-title":"Lymphocyte apoptosis in systemic lupus erythematosus: relationships with Fas expression, serum soluble Fas and disease activity","volume":"8","author":"Courtney","year":"1999","journal-title":"Lupus"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib13","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1038\/nm0396-317","article-title":"Fas ligand in human serum","volume":"2","author":"Tanaka","year":"1996","journal-title":"Nat Med"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib14","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1046\/j.1365-2141.1998.01095.x","article-title":"Elevated serum soluble Fas ligand in natural killer cell proliferative disorders","volume":"103","author":"Kato","year":"1998","journal-title":"Br J Haematol"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib15","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1161\/01.ATV.0000250616.26308.d7","article-title":"Increased soluble Fas plasma levels in subjects at high cardiovascular risk","volume":"27","author":"Blanco-Colio","year":"2007","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib16","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1093\/eurheartj\/ehp004","article-title":"Prognostic value of apoptosis markers in advanced heart failure","volume":"30","author":"Niessner","year":"2009","journal-title":"Eur Heart J"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib17","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1161\/STROKEAHA.110.611301","article-title":"The prognostic impact of soluble apoptosis-stimulating fragment on mortality in patients with carotid atherosclerosis","volume":"42","author":"Hoke","year":"2011","journal-title":"Stroke"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib18","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1016\/j.jacc.2003.10.046","article-title":"Decreased circulating fas ligand in patients with familial combined hyperlipidemia or carotid atherosclerosis","volume":"43","author":"Blanco-Colio","year":"2004","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib19","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.atherosclerosis.2008.02.005","article-title":"Soluble Fas ligand plasma levels are associated with forearm reactive hyperemia in subjects with coronary artery disease. A novel biomarker of endothelial function?","volume":"201","author":"Blanco-Colio","year":"2008","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib20","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1182\/blood.V89.3.910","article-title":"Cytokine-induced apoptosis of human natural killer cells identifies a novel mechanism to regulate the innate immune response","volume":"89","author":"Ross","year":"1997","journal-title":"Blood"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib21","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1002\/j.1460-2075.1995.tb07096.x","article-title":"Expression of the functional soluble form of human Fas ligand in activated lymphocytes","volume":"14","author":"Tanaka","year":"1995","journal-title":"EMBO J"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib22","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1478-811X-6-11","article-title":"Posttranslational regulation of Fas ligand function","volume":"6","author":"Voss","year":"2008","journal-title":"Cell Commun Signal"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib23","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1084\/jem.187.1.123","article-title":"Maximal proliferation of cytotoxic T lymphocytes requires reverse signaling through Fas ligand","volume":"187","author":"Suzuki","year":"1998","journal-title":"J\u00a0Exp Med"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib24","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1002\/jlb.61.2.209","article-title":"Fas involvement in human Nk cell apoptosis: lack of a requirement for CD16-mediated events","volume":"61","author":"Ortaldo","year":"1997","journal-title":"J\u00a0Leukoc Biol"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib25","doi-asserted-by":"crossref","first-page":"e17659","DOI":"10.1371\/journal.pone.0017659","article-title":"Opposing roles for membrane-bound and soluble Fas ligand in glaucoma-associated retinal ganglion cell death","volume":"6","author":"Gregory","year":"2011","journal-title":"PLoS ONE"},{"key":"10.1016\/j.atherosclerosis.2014.01.030_bib26","doi-asserted-by":"crossref","first-page":"535","DOI":"10.18632\/aging.100482","article-title":"Sarcopenia, obesity, and natural killer cell immune senescence in aging: altered cytokine levels as a common mechanism","volume":"4","author":"Lutz","year":"2012","journal-title":"Aging"}],"container-title":["Atherosclerosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021915014000550?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021915014000550?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T00:38:02Z","timestamp":1758155882000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021915014000550"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["S0021915014000550"],"URL":"https:\/\/doi.org\/10.1016\/j.atherosclerosis.2014.01.030","relation":{},"ISSN":["0021-9150"],"issn-type":[{"type":"print","value":"0021-9150"}],"subject":[],"published":{"date-parts":[[2014,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Soluble Fas ligand is associated with natural killer cell dynamics in coronary artery disease","name":"articletitle","label":"Article Title"},{"value":"Atherosclerosis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.atherosclerosis.2014.01.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}