{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T11:33:02Z","timestamp":1793446382863,"version":"4.5.0"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,7,13]],"date-time":"2018-07-13T00:00:00Z","timestamp":1531440000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000274","name":"British Heart Foundation","doi-asserted-by":"publisher","award":["RG\/12\/5\/29576"],"award-info":[{"award-number":["RG\/12\/5\/29576"]}],"id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["091504\/Z\/10\/Z"],"award-info":[{"award-number":["091504\/Z\/10\/Z"]}],"id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["090532\/Z\/09\/Z"],"award-info":[{"award-number":["090532\/Z\/09\/Z"]}],"id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005617","name":"BHF Centre for Research Excellence","doi-asserted-by":"publisher","award":["RE\/13\/1\/30181"],"award-info":[{"award-number":["RE\/13\/1\/30181"]}],"id":[{"id":"10.13039\/501100005617","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000272","name":"National Institute for Health Research (NIHR)","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Oxford Biomedical Research Centre"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","atherosclerosis-journal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Atherosclerosis"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.atherosclerosis.2018.07.019","type":"journal-article","created":{"date-parts":[[2018,7,23]],"date-time":"2018-07-23T18:24:34Z","timestamp":1532370274000},"page":"74-82","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["Effect of irradiation and bone marrow transplantation on angiotensin II-induced aortic inflammation in ApoE knockout mice"],"prefix":"10.1016","volume":"276","author":[{"given":"Jyoti","family":"Patel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gillian","family":"Douglas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alastair G.","family":"Kerr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley B.","family":"Hale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith M.","family":"Channon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.atherosclerosis.2018.07.019_bib1","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1172\/JCI7818","article-title":"Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice","volume":"105","author":"Daugherty","year":"2000","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.atherosclerosis.2018.07.019_bib2","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/978-1-60761-974-1_19","article-title":"Bone marrow transplantations to study gene function in hematopoietic cells","volume":"693","author":"de Winther","year":"2011","journal-title":"Meth. Mol. Biol."},{"issue":"2","key":"10.1016\/j.atherosclerosis.2018.07.019_bib3","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.atherosclerosis.2010.05.030","article-title":"Bone marrow transplantation in mice as a tool for studying the role of hematopoietic cells in metabolic and cardiovascular diseases","volume":"213","author":"Aparicio-Vergara","year":"2010","journal-title":"Atherosclerosis"},{"issue":"10","key":"10.1016\/j.atherosclerosis.2018.07.019_bib4","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1161\/hq1001.096724","article-title":"Effect of gamma-irradiation and bone marrow transplantation on atherosclerosis in LDL receptor-deficient mice","volume":"21","author":"Schiller","year":"2001","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"2","key":"10.1016\/j.atherosclerosis.2018.07.019_bib5","doi-asserted-by":"crossref","first-page":"649","DOI":"10.2353\/ajpath.2006.050409","article-title":"Ionizing radiation accelerates the development of atherosclerotic lesions in ApoE-\/- mice and predisposes to an inflammatory plaque phenotype prone to hemorrhage","volume":"168","author":"Stewart","year":"2006","journal-title":"Am. J. Pathol."},{"issue":"3","key":"10.1016\/j.atherosclerosis.2018.07.019_bib6","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1016\/j.ijrobp.2008.02.031","article-title":"Single-dose and fractionated irradiation promote initiation and progression of atherosclerosis and induce an inflammatory plaque phenotype in ApoE(-\/-) mice","volume":"71","author":"Hoving","year":"2008","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"issue":"2","key":"10.1016\/j.atherosclerosis.2018.07.019_bib7","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1161\/ATVBAHA.117.309524","article-title":"Consideration of sex differences in design and reporting of experimental arterial pathology studies-statement from ATVB council","volume":"38","author":"Robinet","year":"2018","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"8","key":"10.1016\/j.atherosclerosis.2018.07.019_bib8","doi-asserted-by":"crossref","first-page":"3866","DOI":"10.1210\/en.2003-1615","article-title":"Orchidectomy, but not ovariectomy, regulates angiotensin II-induced vascular diseases in apolipoprotein E-deficient mice","volume":"145","author":"Henriques","year":"2004","journal-title":"Endocrinology"},{"issue":"4","key":"10.1016\/j.atherosclerosis.2018.07.019_bib9","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1161\/CIRCULATIONAHA.116.023789","article-title":"Female mice with an XY sex chromosome complement develop severe angiotensin II-induced abdominal aortic aneurysms","volume":"135","author":"Alsiraj","year":"2017","journal-title":"Circulation"},{"issue":"3","key":"10.1016\/j.atherosclerosis.2018.07.019_bib10","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1161\/01.ATV.0000153088.15433.8f","article-title":"Recommendations for blood pressure measurement in animals: summary of an AHA scientific statement from the council on high blood pressure Research, professional and public education subcommittee","volume":"25","author":"Kurtz","year":"2005","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"9","key":"10.1016\/j.atherosclerosis.2018.07.019_bib11","doi-asserted-by":"crossref","first-page":"e131","DOI":"10.1161\/ATV.0000000000000062","article-title":"Recommendation on design, execution, and reporting of animal atherosclerosis studies: a scientific statement from the american Heart association","volume":"37","author":"Daugherty","year":"2017","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"5","key":"10.1016\/j.atherosclerosis.2018.07.019_bib12","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1084\/jem.20052205","article-title":"Lymphocyte recruitment into the aortic wall before and during development of atherosclerosis is partially L-selectin dependent","volume":"203","author":"Galkina","year":"2006","journal-title":"J.\u00a0Exp. Med."},{"issue":"12","key":"10.1016\/j.atherosclerosis.2018.07.019_bib13","doi-asserted-by":"crossref","first-page":"3637","DOI":"10.1172\/JCI38308","article-title":"An adventitial IL-6\/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice","volume":"119","author":"Tieu","year":"2009","journal-title":"J.\u00a0Clin. Invest."},{"issue":"11","key":"10.1016\/j.atherosclerosis.2018.07.019_bib14","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1042\/CS20090372","article-title":"Angiotensin II infusion promotes ascending aortic aneurysms: attenuation by CCR2 deficiency in apoE-\/- mice","volume":"118","author":"Daugherty","year":"2010","journal-title":"Clin. Sci. (Lond.)"},{"issue":"3","key":"10.1016\/j.atherosclerosis.2018.07.019_bib15","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1161\/01.HYP.0000140269.55873.7b","article-title":"Endogenous angiotensin II induces atherosclerotic plaque vulnerability and elicits a Th1 response in ApoE-\/- mice","volume":"44","author":"Mazzolai","year":"2004","journal-title":"Hypertension"},{"issue":"8","key":"10.1016\/j.atherosclerosis.2018.07.019_bib16","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/nrcardio.2017.52","article-title":"Monocytes and macrophages in abdominal aortic aneurysm","volume":"14","author":"Raffort","year":"2017","journal-title":"Nat. Rev. Cardiol."},{"issue":"2","key":"10.1016\/j.atherosclerosis.2018.07.019_bib17","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1161\/ATVBAHA.114.304389","article-title":"Angiotensin II mobilizes spleen monocytes to promote the development of abdominal aortic aneurysm in apoe(-\/-) mice","volume":"35","author":"Mellak","year":"2015","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"5940","key":"10.1016\/j.atherosclerosis.2018.07.019_bib18","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1126\/science.1175202","article-title":"Identification of splenic reservoir monocytes and their deployment to inflammatory sites","volume":"325","author":"Swirski","year":"2009","journal-title":"Science"},{"issue":"5","key":"10.1016\/j.atherosclerosis.2018.07.019_bib19","doi-asserted-by":"crossref","DOI":"10.1152\/ajpheart.00028.2009","article-title":"ANG II infusion promotes abdominal aortic aneurysms independent of increased blood pressure in hypercholesterolemic mice","volume":"296","author":"Cassis","year":"2009","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"3","key":"10.1016\/j.atherosclerosis.2018.07.019_bib20","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1161\/HYPERTENSIONAHA.115.06474","article-title":"Angiotensin II regulation of proliferation, differentiation, and engraftment of hematopoietic stem cells","volume":"67","author":"Kim","year":"2016","journal-title":"Hypertension"},{"issue":"1","key":"10.1016\/j.atherosclerosis.2018.07.019_bib21","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1161\/ATVBAHA.107.152363","article-title":"Critical role of bone marrow angiotensin II type 1 receptor in the pathogenesis of atherosclerosis in apolipoprotein E deficient mice","volume":"28","author":"Fukuda","year":"2008","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"5","key":"10.1016\/j.atherosclerosis.2018.07.019_bib22","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1161\/CIRCRESAHA.110.222844","article-title":"Endothelial cell-specific deficiency of Ang II type 1a receptors attenuates Ang II-induced ascending aortic aneurysms in LDL receptor-\/- mice","volume":"108","author":"Rateri","year":"2011","journal-title":"Circ. Res."},{"issue":"4","key":"10.1016\/j.atherosclerosis.2018.07.019_bib23","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1038\/nm0402-403","article-title":"Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis","volume":"8","author":"Sata","year":"2002","journal-title":"Nat. Med."},{"key":"10.1016\/j.atherosclerosis.2018.07.019_bib24","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.yjmcc.2015.12.007","article-title":"Bone marrow transplantation modulates tissue macrophage phenotype and enhances cardiac recovery after subsequent acute myocardial infarction","volume":"90","author":"Protti","year":"2016","journal-title":"J.\u00a0Mol. Cell. Cardiol."},{"issue":"5","key":"10.1016\/j.atherosclerosis.2018.07.019_bib25","doi-asserted-by":"crossref","DOI":"10.1152\/ajpheart.00821.2014","article-title":"M2 macrophage accumulation in the aortic wall during angiotensin II infusion in mice is associated with fibrosis, elastin loss, and elevated blood pressure","volume":"309","author":"Moore","year":"2015","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.atherosclerosis.2018.07.019_bib26","doi-asserted-by":"crossref","first-page":"17404","DOI":"10.1038\/srep17404","article-title":"Hydrodynamic gene delivery of CC chemokine binding Fc Fusion proteins to target acute vascular inflammation in\u00a0vivo","volume":"5","author":"McNeill","year":"2015","journal-title":"Sci. Rep."},{"issue":"4","key":"10.1016\/j.atherosclerosis.2018.07.019_bib27","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1093\/cvr\/cvp149","article-title":"Low-level laser irradiation inhibits abdominal aortic aneurysm progression in apolipoprotein E-deficient mice","volume":"83","author":"Gavish","year":"2009","journal-title":"Cardiovasc. Res."},{"issue":"5","key":"10.1016\/j.atherosclerosis.2018.07.019_bib28","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1002\/lsm.20635","article-title":"Irradiation with 780 nm diode laser attenuates inflammatory cytokines but upregulates nitric oxide in lipopolysaccharide-stimulated macrophages: implications for the prevention of aneurysm progression","volume":"40","author":"Gavish","year":"2008","journal-title":"Laser Surg. Med."},{"issue":"8","key":"10.1016\/j.atherosclerosis.2018.07.019_bib29","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1002\/lsm.20383","article-title":"Low-level laser irradiation modulates matrix metalloproteinase activity and gene expression in porcine aortic smooth muscle cells","volume":"38","author":"Gavish","year":"2006","journal-title":"Laser Surg. Med."},{"issue":"11","key":"10.1016\/j.atherosclerosis.2018.07.019_bib30","doi-asserted-by":"crossref","first-page":"2320","DOI":"10.1016\/S0022-2275(20)39713-3","article-title":"Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice","volume":"36","author":"Tangirala","year":"1995","journal-title":"J.\u00a0Lipid Res."}],"container-title":["Atherosclerosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021915018312152?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021915018312152?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,8,28]],"date-time":"2022-08-28T02:39:14Z","timestamp":1661654354000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021915018312152"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":30,"alternative-id":["S0021915018312152"],"URL":"https:\/\/doi.org\/10.1016\/j.atherosclerosis.2018.07.019","relation":{},"ISSN":["0021-9150"],"issn-type":[{"value":"0021-9150","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of irradiation and bone marrow transplantation on angiotensin II-induced aortic inflammation in ApoE knockout mice","name":"articletitle","label":"Article Title"},{"value":"Atherosclerosis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.atherosclerosis.2018.07.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}