{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T09:52:30Z","timestamp":1791453150566,"version":"4.3.3"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key R&D Program of China","doi-asserted-by":"publisher","award":["2016YFC1301100"],"award-info":[{"award-number":["2016YFC1301100"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81827806"],"award-info":[{"award-number":["81827806"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81801861"],"award-info":[{"award-number":["81801861"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2018M630373"],"award-info":[{"award-number":["2018M630373"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2019T120283"],"award-info":[{"award-number":["2019T120283"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004027","name":"Hei Long Jiang Postdoctoral Foundation","doi-asserted-by":"publisher","award":["LBH-TZ15"],"award-info":[{"award-number":["LBH-TZ15"]}],"id":[{"id":"10.13039\/501100004027","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","atherosclerosis-journal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Atherosclerosis"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1016\/j.atherosclerosis.2019.08.011","type":"journal-article","created":{"date-parts":[[2019,8,22]],"date-time":"2019-08-22T20:10:49Z","timestamp":1566504649000},"page":"94-100","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":36,"special_numbering":"C","title":["Culprit lesion morphology in young patients with ST-segment elevated myocardial infarction: A clinical, angiographic and optical coherence tomography study"],"prefix":"10.1016","volume":"289","author":[{"given":"Chao","family":"Fang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiannan","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaotao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yidan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4724-3080","authenticated-orcid":false,"given":"Jifei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lulu","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yini","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huai","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiling","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huimin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maoen","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuefeng","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijia","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingfeng","family":"Tu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Xing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3331-229X","authenticated-orcid":false,"given":"Jingbo","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2045-8567","authenticated-orcid":false,"given":"Bo","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib1","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/S0002-9343(99)00218-1","article-title":"Myocardial infarction in young patients","volume":"107","author":"Choudhury","year":"1999","journal-title":"Am. J. Med."},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib2","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.ahj.2004.06.003","article-title":"Impact of age on management and outcome of acute coronary syndrome: observations from the Global Registry of Acute Coronary Events (GRACE)","volume":"149","author":"Avezum","year":"2005","journal-title":"Am. Heart J."},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib3","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.atherosclerosis.2018.10.017","article-title":"Early onset ACS: an age based clinico-epidemiologic and angiographic comparison","volume":"279","author":"Chhabra","year":"2018","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib4","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1177\/2048872614567453","article-title":"Atypical risk factor profile and excellent long-term outcomes of young patients treated with primary percutaneous coronary intervention for ST-elevation myocardial infarction","volume":"5","author":"Rathod","year":"2016","journal-title":"Eur. Heart J. Acute. Cardiovasc. Care."},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib5","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1016\/j.jacc.2013.05.071","article-title":"In vivo diagnosis of plaque erosion and calcified nodule in patients with acute coronary syndrome by intravascular optical coherence tomography","volume":"62","author":"Jia","year":"2013","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib6","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1093\/eurheartj\/ehp433","article-title":"Expert review document on methodology, terminology, and clinical applications of optical coherence tomography: physical principles, methodology of image acquisition, and clinical application for assessment of coronary arteries and atherosclerosis","volume":"31","author":"Prati","year":"2010","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib7","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1093\/eurheartj\/ehv029","article-title":"Plaque rupture and intact fibrous cap assessed by optical coherence tomography portend different outcomes in patients with acute coronary syndrome","volume":"36","author":"Niccoli","year":"2015","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib8","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1016\/j.jcin.2015.02.026","volume":"8","author":"Higuma","year":"2015","journal-title":"JACC Cardiovasc. Interv."},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib9","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.1093\/eurheartj\/ehy101","article-title":"In vivo predictors of plaque erosion in patients with ST-segment elevation myocardial infarction: a clinical, angiographical, and intravascular optical coherence tomography study","volume":"39","author":"Dai","year":"2018","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib10","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1161\/hc0402.102952","article-title":"Traditional risk factors and the incidence of sudden coronary death with and without coronary thrombosis in blacks","volume":"105","author":"Burke","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib11","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1161\/ATVBAHA.112.300154","article-title":"Mechanisms of coronary thrombosis in cigarette smoke exposure","volume":"33","author":"Barua","year":"2013","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib12","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1056\/NEJM199705013361802","article-title":"Coronary risk factors and plaque morphology in men with coronary disease who died suddenly","volume":"336","author":"Burke","year":"1997","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib13","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1161\/01.ATV.20.5.1262","article-title":"Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions","volume":"20","author":"Virmani","year":"2000","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib14","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.1161\/01.CIR.97.21.2110","article-title":"Effect of risk factors on the mechanism of acute thrombosis and sudden coronary death in women","volume":"97","author":"Burke","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib15","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1161\/01.ATV.0000034021.92658.4C","article-title":"Differential accumulation of proteoglycans and hyaluronan in culprit lesions: insights into plaque erosion","volume":"22","author":"Kolodgie","year":"2002","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib16","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1007\/s10753-017-0622-5","article-title":"Intermediate molecular mass hyaluronan and CD44 receptor interactions enhance neutrophil phagocytosis and IL-8 production via p38- and ERK1\/2-MAPK signalling pathways","volume":"40","author":"Lu","year":"2017","journal-title":"Inflammation"},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib17","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1016\/j.jacc.2018.06.072","article-title":"Alterations of hyaluronan metabolism in acute coronary syndrome: implications for plaque erosion","volume":"72","author":"Pedicino","year":"2018","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib18","doi-asserted-by":"crossref","first-page":"929","DOI":"10.4244\/EIJV8I8A142","article-title":"Age- and gender-related changes in plaque composition in patients with acute coronary syndrome: the PROSPECT study","volume":"8","author":"Ruiz-Garcia","year":"2012","journal-title":"EuroIntervention"},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib19","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1161\/01.CIR.0000048892.83521.58","article-title":"Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a \"set up\" for vascular disease","volume":"107","author":"Lakatta","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib20","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.jacc.2018.05.027","article-title":"Coronary calcium score and cardiovascular risk","volume":"72","author":"Greenland","year":"2018","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib21","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.amjcard.2013.02.048","article-title":"Coronary superficial and spotty calcium deposits in culprit coronary lesions of acute coronary syndrome as determined by optical coherence tomography","volume":"112","author":"Mizukoshi","year":"2013","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib22","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1016\/j.cjca.2017.05.003","article-title":"Relation between superficial calcifications and plaque rupture: an optical coherence tomography study","volume":"33","author":"Zhan","year":"2017","journal-title":"Can. J. Cardiol."},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib23","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.jcin.2018.12.013","article-title":"Calcified plaques in patients with acute coronary syndromes","volume":"12","author":"Sugiyama","year":"2019","journal-title":"JACC Cardiovasc. Interv."},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib24","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1016\/j.jacc.2012.03.012","article-title":"Spotty calcification as a marker of accelerated progression of coronary atherosclerosis: insights from serial intravascular ultrasound","volume":"59","author":"Kataoka","year":"2012","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib25","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.atherosclerosis.2016.02.010","article-title":"Association between cholesterol crystals and culprit lesion vulnerability in patients with acute coronary syndrome: an optical coherence tomography study","volume":"247","author":"Dai","year":"2016","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib26","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.atherosclerosis.2019.02.009","article-title":"Incidence, factors, and clinical significance of cholesterol crystals in coronary plaque: an optical coherence tomography study","volume":"283","author":"Fujiyoshi","year":"2019","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.atherosclerosis.2019.08.011_bib27","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1093\/eurheartj\/ehv653","article-title":"Cholesterol crystal induced arterial inflammation and destabilization of atherosclerotic plaque","volume":"37","author":"Janoudi","year":"2016","journal-title":"Eur. Heart J."}],"container-title":["Atherosclerosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002191501931456X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002191501931456X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,10,9]],"date-time":"2019-10-09T08:17:29Z","timestamp":1570609049000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002191501931456X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":27,"alternative-id":["S002191501931456X"],"URL":"https:\/\/doi.org\/10.1016\/j.atherosclerosis.2019.08.011","relation":{},"ISSN":["0021-9150"],"issn-type":[{"value":"0021-9150","type":"print"}],"subject":[],"published":{"date-parts":[[2019,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Culprit lesion morphology in young patients with ST-segment elevated myocardial infarction: A clinical, angiographic and optical coherence tomography study","name":"articletitle","label":"Article Title"},{"value":"Atherosclerosis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.atherosclerosis.2019.08.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}