{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T17:28:32Z","timestamp":1789752512989,"version":"4.0.1"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003196","name":"Ministero della Salute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100030732","name":"MSD","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100030732","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004339","name":"Sanofi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004339","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["atherosclerosis-journal.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Atherosclerosis"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.atherosclerosis.2026.120691","type":"journal-article","created":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T16:11:58Z","timestamp":1772035918000},"page":"120691","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Real-world management of familial hypercholesterolemia in paediatric patients: a 3-year follow-up from the LIPIGEN registry"],"prefix":"10.1016","volume":"415","author":[{"given":"Federica","family":"Galimberti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Elena","family":"Capra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Olmastroni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"Braghiroli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Banderali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Baratta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giacomo","family":"Biasucci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Biolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola Sabrina","family":"Buonuomo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo Baldassare","family":"Cefal\u00f9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Cipollone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Citroni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"D'Addato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simonetta","family":"Genovesi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ornella","family":"Guardamagna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Iughetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Mandraffino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilenia","family":"Minicocci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuliana Germana","family":"Mombelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiziana","family":"Montalcini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Nascimbeni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelina","family":"Passaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Pirro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabetta","family":"Rinaldi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Sbrana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Scicali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrizia","family":"Suppressa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo Jos\u00e8","family":"Werba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Grazia","family":"Zenti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcello","family":"Arca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Averna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrizia","family":"Tarugi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastiano","family":"Calandra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberico Luigi","family":"Catapano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2213-9383","authenticated-orcid":false,"given":"Cristina","family":"Pederiva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5124-5361","authenticated-orcid":false,"given":"Manuela","family":"Casula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Abello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Bianconi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Brambilla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrizia","family":"Bruzzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arrigo","family":"Cicero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Cocomello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damiano","family":"D'Ardes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"D'Erasmo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatrice Dal","family":"Pino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Fainelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvelise","family":"Ferro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Formisano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Franceschi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonina","family":"Giammanco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Giussani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simonetta","family":"Lugari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Lutterotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Moriglia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandro","family":"Muntoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Pavanello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Piras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"Piro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Livia","family":"Pisciotta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Rizzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Sani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Spannella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arianna","family":"Toscano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"Vecchio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Zambon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.atherosclerosis.2026.120691_bib1","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1097\/JXX.0000000000000930","article-title":"The genetics of autosomal dominant familial hypercholesterolemia","volume":"36","author":"Anderson","year":"2024","journal-title":"J Am Assoc Nurse Pract"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib2","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2020.574474","article-title":"Genetics of familial hypercholesterolemia: new insights","volume":"11","author":"Vrablik","year":"2020","journal-title":"Front Genet"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib3","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/S2213-8587(19)30264-5","article-title":"Rare dyslipidaemias, from phenotype to genotype to management: a European atherosclerosis society task force consensus statement","volume":"8","author":"Hegele","year":"2020","journal-title":"Lancet Diabetes Endo"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib4","doi-asserted-by":"crossref","first-page":"3478","DOI":"10.1093\/eurheartj\/eht273","article-title":"Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European atherosclerosis society","volume":"34","author":"Nordestgaard","year":"2013","journal-title":"Eur Heart J"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib5","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1161\/CIRCULATIONAHA.119.044795","article-title":"Prevalence of familial hypercholesterolemia among the general population and patients with atherosclerotic cardiovascular disease: a systematic review and meta-analysis","volume":"141","author":"Hu","year":"2020","journal-title":"Circulation"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib6","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2022.840797","article-title":"Familial hypercholesterolemia prevalence among ethnicities-systematic review and meta-analysis","volume":"13","author":"Toft-Nielsen","year":"2022","journal-title":"Front Genet"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib7","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1194\/jlr.S074039","article-title":"Knowns and unknowns in the care of pediatric familial hypercholesterolemia","volume":"58","author":"Martin","year":"2017","journal-title":"J Lipid Res"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib8","doi-asserted-by":"crossref","DOI":"10.1038\/nrdp.2017.93","article-title":"Familial hypercholesterolaemia","volume":"3","author":"Defesche","year":"2017","journal-title":"Nat Rev Dis Primers"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib9","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1007\/s11883-021-00959-8","article-title":"Prevention of atherosclerotic cardiovascular disease in children with familial hypercholesterolemia","volume":"23","author":"Peterson","year":"2021","journal-title":"Curr Atheroscler Rep"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.atherosclerosis.2023.117231","article-title":"Refinement of the diagnostic approach for the identification of children and adolescents affected by familial hypercholesterolemia: evidence from the LIPIGEN study","volume":"385","author":"Casula","year":"2023","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib11","article-title":"Genetic testing for familial hypercholesterolemia-past, present, and future","volume":"62","author":"Futema","year":"2021","journal-title":"J Lipid Res"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib12","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1038\/s41569-024-01039-5","article-title":"The LDL cumulative exposure hypothesis: evidence and practical applications","volume":"21","author":"Ference","year":"2024","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib13","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1016\/j.jacc.2018.06.046","article-title":"Impact of lipids on cardiovascular health: JACC health promotion series","volume":"72","author":"Ference","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib14","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1093\/eurheartj\/ehz455","article-title":"2019 ESC\/EAS guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk","volume":"41","author":"Mach","year":"2020","journal-title":"Eur Heart J"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib15","doi-asserted-by":"crossref","first-page":"531","DOI":"10.5551\/jat.CR006","article-title":"Guidelines for the diagnosis and treatment of pediatric familial hypercholesterolemia 2022","volume":"30","author":"Harada-Shiba","year":"2023","journal-title":"J Atheroscler Thromb"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib16","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2023.1113454","article-title":"Corrigendum: the role of registers in increasing knowledge and improving management of children and adolescents affected by familial hypercholesterolemia: the LIPIGEN pediatric group","volume":"14","author":"Gazzotti","year":"2023","journal-title":"Front Genet"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib17","doi-asserted-by":"crossref","first-page":"e35","DOI":"10.1016\/j.atherosclerosissup.2021.01.007","article-title":"How registers could enhance knowledge and characterization of genetic dyslipidaemias: the experience of the LIPIGEN in Italy and of other networks for familial hypercholesterolemia","volume":"42","author":"Gazzotti","year":"2020","journal-title":"Atherosclerosis Suppl"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib18","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.atherosclerosissup.2017.07.001","article-title":"Familial hypercholesterolemia: the Italian atherosclerosis society network (LIPIGEN)","volume":"29","author":"Averna","year":"2017","journal-title":"Atherosclerosis Supp"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib19","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1007\/s11883-014-0482-5","article-title":"Familial hypercholesterolemia--epidemiology, diagnosis, and screening","volume":"17","author":"Singh","year":"2015","journal-title":"Curr Atheroscler Rep"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib20","first-page":"76","article-title":"WHO child growth standards based on length\/height, weight and age","volume":"450","year":"2006","journal-title":"Acta Paediatr Suppl"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib21","doi-asserted-by":"crossref","first-page":"660","DOI":"10.2471\/BLT.07.043497","article-title":"Development of a WHO growth reference for school-aged children and adolescents","volume":"85","author":"de Onis","year":"2007","journal-title":"Bull World Health Organ"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib22","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines11030883","article-title":"From NAFLD to MAFLD: definition, pathophysiological basis and cardiovascular implications","volume":"11","author":"Boccatonda","year":"2023","journal-title":"Biomedicines"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib23","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24021366","article-title":"Statins in children, an update","volume":"24","author":"Fiorentino","year":"2023","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib24","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.1093\/eurheartj\/ehv157","article-title":"Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment","volume":"36","author":"Wiegman","year":"2015","journal-title":"Eur Heart J"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib25","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1136\/archdischild-2015-308570","article-title":"The UK paediatric familial hypercholesterolaemia register: preliminary data","volume":"102","author":"Ramaswami","year":"2017","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib26","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.jpeds.2020.09.042","article-title":"Children with heterozygous familial hypercholesterolemia in the United States: data from the Cascade screening for awareness and Detection-FH registry","volume":"229","author":"de Ferranti","year":"2021","journal-title":"J Pediatr"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib27","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.arcped.2024.01.004","article-title":"Treatment of pediatric heterozygous familial hypercholesterolemia 7 years after the EAS recommendations: real-world results from a large French cohort","volume":"31","author":"Peretti","year":"2024","journal-title":"Arch Pediatr : Organ Off Soc Franc Pediatr"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib28","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.jacl.2017.11.009","article-title":"Treatment goal attainment in children with familial hypercholesterolemia: a cohort study of 302 children in Norway","volume":"12","author":"Bogsrud","year":"2018","journal-title":"J Clin Lipidol"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib29","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1007\/s12687-024-00725-8","article-title":"\"I don't think people should die young\": perspectives of parents with children diagnosed with familial hypercholesterolemia","volume":"15","author":"Tsai","year":"2024","journal-title":"J Commun Genet"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib30","doi-asserted-by":"crossref","DOI":"10.3390\/nu15153468","article-title":"Clinical approach in the management of paediatric patients with familial hypercholesterolemia: a national survey conducted by the LIPIGEN paediatric group","volume":"15","author":"Pederiva","year":"2023","journal-title":"Nutrients"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib31","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1186\/s13052-022-01257-y","article-title":"Detecting familial hypercholesterolemia in children and adolescents: potential and challenges","volume":"48","author":"Banderali","year":"2022","journal-title":"Ital J Pediatr"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib32","doi-asserted-by":"crossref","first-page":"152","DOI":"10.5114\/pedm.2022.116112","article-title":"Familial hypercholesterolemia - treatment update in children, systematic review","volume":"28","author":"Ziolkowska","year":"2022","journal-title":"Pediatr Endocrinol Diabetes Metab"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib33","article-title":"The importance of genetic testing for familial hypercholesterolemia: a pediatric pilot study","volume":"60","author":"Constantin","year":"2024","journal-title":"Medicina (Kaunas)"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib34","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.jacc.2018.05.044","article-title":"Clinical genetic testing for familial hypercholesterolemia: JACC scientific expert panel","volume":"72","author":"Sturm","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.atherosclerosis.2019.09.005","article-title":"Current management of children and young people with heterozygous familial hypercholesterolaemia - HEART UK statement of care","volume":"290","author":"Ramaswami","year":"2019","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib36","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.atherosclerosis.2020.11.027","article-title":"Genetic testing is essential for initiating statin therapy in children with familial hypercholesterolemia: examples from scandinavia","volume":"316","author":"Svendsen","year":"2021","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib37","doi-asserted-by":"crossref","DOI":"10.3390\/nu14030569","article-title":"Nutraceuticals in paediatric patients with dyslipidaemia","volume":"14","author":"Banderali","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib38","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.atherosclerosis.2009.09.014","article-title":"Evaluation of cholesterol lowering treatment of patients with familial hypercholesterolemia: a large cross-sectional study in the Netherlands","volume":"209","author":"Pijlman","year":"2010","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib39","first-page":"444","article-title":"Attainment of LDL cholesterol treatment goals in children and adolescents with familial hypercholesterolemia","volume":"70","author":"Saltijeral","year":"2017","journal-title":"Safeheart Follow-up Reg Revis Espanol Cardiol"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib40","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.120.020126","article-title":"Treatment inertia in patients with familial hypercholesterolemia","volume":"10","author":"Langer","year":"2021","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.atherosclerosis.2026.120691_bib41","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/s11883-024-01248-w","article-title":"Ezetimibe: integrating established use with new evidence - a comprehensive review","volume":"27","author":"Olmastroni","year":"2024","journal-title":"Curr Atheroscler Rep"}],"container-title":["Atherosclerosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021915026000572?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021915026000572?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T04:44:46Z","timestamp":1779252286000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021915026000572"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":41,"alternative-id":["S0021915026000572"],"URL":"https:\/\/doi.org\/10.1016\/j.atherosclerosis.2026.120691","relation":{},"ISSN":["0021-9150"],"issn-type":[{"value":"0021-9150","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Real-world management of familial hypercholesterolemia in paediatric patients: a 3-year follow-up from the LIPIGEN registry","name":"articletitle","label":"Article Title"},{"value":"Atherosclerosis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.atherosclerosis.2026.120691","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"120691"}}