{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T02:36:21Z","timestamp":1781663781986,"version":"3.54.5"},"reference-count":10,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2011,5,1]],"date-time":"2011-05-01T00:00:00Z","timestamp":1304208000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,5,1]],"date-time":"2011-05-01T00:00:00Z","timestamp":1304208000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["annalsthoracicsurgery.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Annals of Thoracic Surgery"],"published-print":{"date-parts":[[2011,5]]},"DOI":"10.1016\/j.athoracsur.2010.10.077","type":"journal-article","created":{"date-parts":[[2011,4,25]],"date-time":"2011-04-25T10:12:45Z","timestamp":1303726365000},"page":"1606-1608","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Hemophilia A in Cardiac Operations: A Model of Reduced Thrombin Generation"],"prefix":"10.1016","volume":"91","author":[{"given":"Susanne","family":"Lison","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Spannagl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wulf","family":"Dietrich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.athoracsur.2010.10.077_bib1","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/j.1365-2516.2006.01283.x","article-title":"Use of factor VIII replacement during open heart surgery in a patient with haemophilia A","volume":"12","author":"Stine","year":"2006","journal-title":"Haemophilia"},{"key":"10.1016\/j.athoracsur.2010.10.077_bib2","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1046\/j.1365-2516.2000.00384.x","article-title":"Cardiac surgery and catheterization in patients with haemophilia","volume":"6","author":"MacKinlay","year":"2000","journal-title":"Haemophilia"},{"key":"10.1016\/j.athoracsur.2010.10.077_bib3","doi-asserted-by":"crossref","first-page":"2315","DOI":"10.1016\/j.athoracsur.2006.06.072","article-title":"Thrombin during cardiopulmonary bypass","volume":"82","author":"Edmunds","year":"2006","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.athoracsur.2010.10.077_bib4","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1111\/j.1538-7836.2008.03201.x","article-title":"Cardiovascular disease in patients with hemophilia","volume":"7","author":"Tuinenburg","year":"2009","journal-title":"J Thromb Haemost"},{"issue":"suppl 2","key":"10.1016\/j.athoracsur.2010.10.077_bib5","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1055\/s-2006-946908","article-title":"Hemophilia therapy and blood-borne pathogen risk","volume":"32","author":"Knight","year":"2006","journal-title":"Semin Thromb Hemost"},{"issue":"suppl 5","key":"10.1016\/j.athoracsur.2010.10.077_bib6","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1111\/j.1365-2516.2007.01571.x","article-title":"Inhibitor development in haemophilia A: the role of von Willebrand factor\/factor VIII concentrates","volume":"13","author":"Goudemand","year":"2007","journal-title":"Haemophilia"},{"key":"10.1016\/j.athoracsur.2010.10.077_bib7","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1111\/j.1365-2516.2004.00906.x","article-title":"Haemophilia and thrombophilia: an unexpected association!","volume":"10","author":"Dargaud","year":"2004","journal-title":"Haemophilia"},{"key":"10.1016\/j.athoracsur.2010.10.077_bib8","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1111\/j.1365-2516.2008.01895.x","article-title":"Cardiac surgery in patients with haemophilia","volume":"15","author":"Tang","year":"2009","journal-title":"Haemophilia"},{"key":"10.1016\/j.athoracsur.2010.10.077_bib9","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.jtcvs.2005.10.018","article-title":"Activation of the coagulation system during coronary artery bypass grafting: comparison between on-pump and off-pump techniques","volume":"131","author":"Paparella","year":"2006","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.athoracsur.2010.10.077_bib10","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1378\/chest.128.1.229","article-title":"Coagulation activation and organ dysfunction following cardiac surgery","volume":"128","author":"Dixon","year":"2005","journal-title":"Chest"}],"container-title":["The Annals of Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003497510024239?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003497510024239?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T01:09:47Z","timestamp":1757725787000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003497510024239"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2011,5]]}},"alternative-id":["S0003497510024239"],"URL":"https:\/\/doi.org\/10.1016\/j.athoracsur.2010.10.077","relation":{},"ISSN":["0003-4975"],"issn-type":[{"value":"0003-4975","type":"print"}],"subject":[],"published":{"date-parts":[[2011,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hemophilia A in Cardiac Operations: A Model of Reduced Thrombin Generation","name":"articletitle","label":"Article Title"},{"value":"The Annals of Thoracic Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.athoracsur.2010.10.077","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}