{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:53:03Z","timestamp":1773103983787,"version":"3.50.1"},"reference-count":32,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["annalsthoracicsurgery.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Annals of Thoracic Surgery"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1016\/j.athoracsur.2015.05.094","type":"journal-article","created":{"date-parts":[[2015,8,13]],"date-time":"2015-08-13T03:06:44Z","timestamp":1439435204000},"page":"2270-2276","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Coexisting Mitral Regurgitation Impairs Survival After Transcatheter Aortic Valve Implantation"],"prefix":"10.1016","volume":"100","author":[{"given":"Hisato","family":"Takagi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takuya","family":"Umemoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.athoracsur.2015.05.094_bib1","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1053\/j.jvca.2013.11.003","article-title":"Incidental moderate mitral regurgitation in patients undergoing aortic valve replacement for aortic stenosis: review of guidelines and current evidence","volume":"28","author":"Ramakrishna","year":"2014","journal-title":"J\u00a0Cardiothorac Vasc Anesth"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib2","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1111\/j.1540-8191.2009.00965.x","article-title":"Is concomitant surgery for moderate functional mitral regurgitation indicated during aortic valve replacement for aortic stenosis? A systematic review and evidence-based recommendations","volume":"25","author":"Alghamdi","year":"2010","journal-title":"J\u00a0Card Surg"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib3","first-page":"1087","article-title":"Aortic valve replacement for aortic stenosis in patients with concomitant mitral regurgitation: should the mitral valve be dealt with?","volume":"40","author":"Harling","year":"2011","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib4","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1093\/eurheartj\/ehq378","article-title":"Percutaneous double valve intervention","volume":"32","author":"S\u00fcrder","year":"2011","journal-title":"Eur Heart J"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib5","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1016\/j.jcin.2011.05.009","article-title":"The first report of transcatheter aortic valve implantation and percutaneous mitral valve repair in the same patient","volume":"4","author":"Madder","year":"2011","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib6","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/j.amjcard.2011.05.017","article-title":"Percutaneous double-valve interventions for aortic stenosis and pure mitral regurgitation","volume":"108","author":"Ong","year":"2011","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib7","first-page":"650","article-title":"Percutaneous treatment of aortic stenosis and mitral regurgitation in the same patient: first human cases description","volume":"78","author":"Barbanti","year":"2011","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib8","first-page":"896","article-title":"Complete interventional heart repair of multiple concomitant cardiac pathologies in a staged approach","volume":"81","author":"Puls","year":"2013","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib9","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/j.ijcard.2012.03.060","article-title":"Bivalvular transcatheter treatment of high-surgical-risk patients with coexisting severe aortic stenosis and significant mitral regurgitation","volume":"167","author":"Rudolph","year":"2013","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib10","first-page":"E552","article-title":"Staged total percutaneous treatment of aortic valve pathology and mitral regurgitation: Institutional experience","volume":"82","author":"Kische","year":"2013","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib11","doi-asserted-by":"crossref","first-page":"2643","DOI":"10.1016\/j.jacc.2014.02.573","article-title":"Significant mitral regurgitation left untreated at the time of aortic valve replacement: a comprehensive review of a frequent entity in the transcatheter aortic valve replacement era","volume":"63","author":"Nombela-Franco","year":"2014","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib12","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.2307\/2533446","article-title":"Operating characteristics of a rank correlation test for publication bias","volume":"50","author":"Begg","year":"1994","journal-title":"Biometrics"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib13","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib14","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1136\/heartjnl-2013-303910","article-title":"Progressive rise in red cell distribution width is associated with poor outcome after transcatheter aortic valve implantation","volume":"99","author":"Aung","year":"2013","journal-title":"Heart"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib15","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1161\/CIRCULATIONAHA.113.001822","article-title":"Interplay between mitral regurgitation and transcatheter aortic valve replacement with the CoreValve Revalving System: a multicenter registry","volume":"128","author":"Bedogni","year":"2013","journal-title":"Circulation"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib16","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.ijcard.2014.03.011","article-title":"Does residual aortic regurgitation after transcatheter aortic valve implantation increase mortality in all patients? The importance of baseline natriuretic peptides","volume":"173","author":"Borz","year":"2014","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib17","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.amjcard.2013.03.024","article-title":"Predictors of one-year mortality after transcatheter aortic valve implantation for severe symptomatic aortic stenosis","volume":"112","author":"Zahn","year":"2013","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib18","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1016\/j.athoracsur.2013.11.025","article-title":"Improved mitral valve performance after transapical aortic valve implantation","volume":"97","author":"Haensig","year":"2014","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib19","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.athoracsur.2012.08.030","article-title":"Transcatheter aortic valve implantation in patients with concomitant mitral and tricuspid regurgitation","volume":"95","author":"Hutter","year":"2013","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib20","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1136\/heartjnl-2014-305775","article-title":"Impact of preprocedural mitral regurgitation upon mortality after transcatheter aortic valve implantation (TAVI) for severe aortic stenosis","volume":"100","author":"Khawaja","year":"2014","journal-title":"Heart"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib21","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1161\/CIRCINTERVENTIONS.113.000409","article-title":"Prevalence, factors associated with, and prognostic effects of preoperative anemia on short- and long-term mortality in patients undergoing transcatheter aortic valve implantation","volume":"6","author":"Nuis","year":"2013","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib22","first-page":"e001895","article-title":"Impact of mitral regurgitation on clinical outcomes of patients with low-ejection fraction, low-gradient severe aortic stenosis undergoing transcatheter aortic valve implantation","volume":"8","author":"O'Sullivan","year":"2015","journal-title":"Circ Cardiovasc\u00a0Interv"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib23","doi-asserted-by":"crossref","first-page":"2776","DOI":"10.1161\/CIRCULATIONAHA.113.003885","article-title":"Impact of preoperative moderate\/severe mitral regurgitation on 2-year outcome after transcatheter and surgical aortic valve replacement: insight from the Placement of Aortic Transcatheter Valve (PARTNER) Trial Cohort A","volume":"128","author":"Barbanti","year":"2013","journal-title":"Circulation"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib24","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/j.amjcard.2013.11.038","article-title":"Long-term prognostic value and serial changes of plasma N-terminal prohormone B-type natriuretic peptide in patients undergoing transcatheter aortic valve implantation","volume":"113","author":"Ribeiro","year":"2014","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib25","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1016\/j.jacc.2009.12.014","article-title":"Transcatheter aortic valve implantation for the treatment of severe symptomatic aortic stenosis in patients at very high or prohibitive surgical risk: acute and late outcomes of the multicenter Canadian experience","volume":"55","author":"Rod\u00e9s-Cabau","year":"2010","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib26","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1161\/CIRCULATIONAHA.110.946533","article-title":"Incidence and predictors of early and late mortality after transcatheter aortic valve implantation in 663 patients with severe aortic stenosis","volume":"123","author":"Tamburino","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib27","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/j.recesp.2013.06.011","article-title":"In-hospital and mid-term predictors of mortality after transcatheter aortic valve implantation: data from the TAVI national registry 2010-2011","volume":"66","author":"Sabat\u00e9","year":"2013","journal-title":"Rev Esp Cardiol"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib28","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.4244\/EIJV8I12A209","article-title":"The 2011-12 pilot European Sentinel Registry of Transcatheter Aortic Valve Implantation: in-hospital results in 4,571 patients","volume":"8","author":"Di Mario","year":"2013","journal-title":"EuroIntervention"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib29","doi-asserted-by":"crossref","first-page":"2068","DOI":"10.1016\/j.jacc.2012.02.020","article-title":"Transcatheter aortic valve replacement: outcomes of patients with moderate or severe mitral regurgitation","volume":"59","author":"Toggweiler","year":"2012","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib30","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/j.amjcard.2014.06.022","article-title":"Meta-analysis of mortality outcomes and mitral regurgitation evolution in 4,839 patients having transcatheter aortic valve implantation for severe aortic stenosis","volume":"114","author":"Sannino","year":"2014","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib31","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1016\/j.amjcard.2015.01.022","article-title":"Meta-analysis of the impact of mitral regurgitation on outcomes after transcatheter aortic valve implantation","volume":"115","author":"Chakravarty","year":"2015","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.athoracsur.2015.05.094_bib32","unstructured":"Reeves BC, Deeks JJ, Higgins JP, Wells GA. Chapter 13: Including non-randomized studies. In: Higgins JP, Green S, eds. Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org."}],"container-title":["The Annals of Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003497515009339?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003497515009339?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T03:24:08Z","timestamp":1757733848000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003497515009339"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":32,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["S0003497515009339"],"URL":"https:\/\/doi.org\/10.1016\/j.athoracsur.2015.05.094","relation":{},"ISSN":["0003-4975"],"issn-type":[{"value":"0003-4975","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Coexisting Mitral Regurgitation Impairs Survival After Transcatheter Aortic Valve Implantation","name":"articletitle","label":"Article Title"},{"value":"The Annals of Thoracic Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.athoracsur.2015.05.094","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}