{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:05:33Z","timestamp":1785542733432,"version":"3.56.0"},"reference-count":31,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["annalsthoracicsurgery.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Annals of Thoracic Surgery"],"published-print":{"date-parts":[[2017,5]]},"DOI":"10.1016\/j.athoracsur.2016.12.042","type":"journal-article","created":{"date-parts":[[2017,3,31]],"date-time":"2017-03-31T03:17:11Z","timestamp":1490930231000},"page":"1668-1675","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":37,"title":["A Meta-Analysis of Postoperative Radiotherapy for Thymic Carcinoma"],"prefix":"10.1016","volume":"103","author":[{"given":"Masatsugu","family":"Hamaji","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohan M.","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed Osman","family":"Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron","family":"Bettenhausen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun-Sung","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryan M.","family":"Burt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.athoracsur.2016.12.042_bib1","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.ejca.2007.11.004","article-title":"Thymic epithelial tumours: a population-based study of the incidence, diagnostic procedures and therapy","volume":"44","author":"de Jong","year":"2008","journal-title":"Eur J Cancer"},{"issue":"Suppl","key":"10.1016\/j.athoracsur.2016.12.042_bib2","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1097\/JTO.0b013e3181f1f62d","article-title":"Epidemiology of thymoma and associated malignancies","volume":"5","author":"Engels","year":"2010","journal-title":"J\u00a0Thorac Oncol"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib3","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1093\/ejcts\/ezt649","article-title":"Tumours of the thymus: a cohort study of prognostic factors from the European Society of Thoracic Surgeons database","volume":"46","author":"Ruffini","year":"2014","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib4","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1016\/S0003-4975(03)00555-1","article-title":"Therapy for thymic epithelial tumors: a clinical study of 1,320 patients from Japan","volume":"76","author":"Kondo","year":"2003","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib5","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.jtcvs.2014.09.124","article-title":"Thymic carcinoma outcomes and prognosis: results of an international analysis","volume":"149","author":"Ahmad","year":"2015","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib6","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1097\/JTO.0000000000000128","article-title":"Thymic carcinoma: a cohort study of patients from the European Society of Thoracic Surgeons database","volume":"9","author":"Ruffini","year":"2014","journal-title":"J\u00a0Thorac Oncol"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib7","unstructured":"National Comprehensive Cancer Network clinical practice guidelines in oncology. Thymomas and thymic carcinomas version 3. 2016. Available at https:\/\/www.nccn.org\/professionals\/physician_gls\/pdf\/thymic.pdf. Accessed September 5,\u00a02016."},{"issue":"Suppl 5","key":"10.1016\/j.athoracsur.2016.12.042_bib8","doi-asserted-by":"crossref","first-page":"v40","DOI":"10.1093\/annonc\/mdv277","article-title":"Thymic epithelial tumours: ESMO clinical practice guidelines for diagnosis, treatment and follow-up","volume":"26","author":"Girard","year":"2015","journal-title":"Ann Oncol"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib9","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1016\/j.ejso.2014.05.011","article-title":"Outcomes after surgical resection of thymic carcinoma: a study from a single tertiary referral centre","volume":"40","author":"Song","year":"2014","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib10","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1093\/ejcts\/ezv239","article-title":"Long-term outcome and prognostic factors of surgically treated thymic carcinoma: results of 306 cases from a Japanese nationwide database study","volume":"49","author":"Hishida","year":"2016","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib11","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jtcvs.2009.03.033","article-title":"Comparison of patterns of relapse in thymic carcinoma and thymoma","volume":"138","author":"Huang","year":"2009","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11748-011-0814-0","article-title":"Thymoma and thymic carcinoma","volume":"60","author":"Venuta","year":"2012","journal-title":"Gen Thorac Cardiovasc Surg"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib13","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/1745-6215-8-16","article-title":"Practical methods for incorporating summary time-to-event data into meta-analysis","volume":"8","author":"Tierney","year":"2007","journal-title":"Trials"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib14","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1002\/sim.1186","article-title":"Quantifying heterogeneity in a meta-analysis","volume":"21","author":"Higgins","year":"2002","journal-title":"Stat Med"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib15","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1136\/bmj.39343.408449.80","article-title":"Uncertainty in heterogeneity estimates in meta-analyses","volume":"335","author":"Ioannidis","year":"2007","journal-title":"Br Med J"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib16","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1002\/cncr.29166","article-title":"Postoperative radiotherapy is effective for thymic carcinoma but not for thymoma in stage II and III thymic epithelial tumors: the Japanese Association for Research on the Thymus database study","volume":"121","author":"Omasa","year":"2015","journal-title":"Cancer"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib17","doi-asserted-by":"crossref","first-page":"699","DOI":"10.2147\/OTT.S78791","article-title":"Treatment and prognosis of Masaoka stage 3 thymic carcinoma: a retrospective study of 32 cases","volume":"8","author":"Sun","year":"2015","journal-title":"OncoTargets Ther"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib18","doi-asserted-by":"crossref","first-page":"3115","DOI":"10.1002\/cncr.10588","article-title":"Treatment and prognosis of thymic carcinoma: a retrospective analysis of 40 cases","volume":"94","author":"Ogawa","year":"2002","journal-title":"Cancer"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib19","doi-asserted-by":"crossref","first-page":"e0146609","DOI":"10.1371\/journal.pone.0146609","article-title":"Adjuvant therapy for thymic carcinoma\u2014a decade of experience in a Taiwan national teaching hospital","volume":"11","author":"Tseng","year":"2016","journal-title":"PLoS ONE"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib20","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1016\/j.athoracsur.2013.12.024","article-title":"Factors predicting recurrence and postrecurrence survival in completely resected thymic carcinoma","volume":"97","author":"Yen","year":"2014","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib21","first-page":"2503","article-title":"Treatment and survival analyses of completely resected thymic carcinoma patients","volume":"8","author":"Mao","year":"2015","journal-title":"OncoTargets Ther"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib22","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1309\/AJCP88FZTWANLRCB","article-title":"Thymic carcinoma, part 1: a clinicopathologic and immunohistochemical study of 65 cases","volume":"138","author":"Weissferdt","year":"2012","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib23","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1245\/s10434-015-4825-4","article-title":"Long-term survival after surgical treatment of thymic carcinoma: a retrospective analysis from the Chinese Alliance for Research of Thymoma database","volume":"23","author":"Fu","year":"2016","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib24","doi-asserted-by":"crossref","first-page":"696","DOI":"10.21037\/jtd.2016.03.31","article-title":"The application of postoperative chemotherapy in thymic tumors and its prognostic effect","volume":"8","author":"Ma","year":"2016","journal-title":"J\u00a0Thorac Dis"},{"issue":"Suppl","key":"10.1016\/j.athoracsur.2016.12.042_bib25","doi-asserted-by":"crossref","first-page":"1743","DOI":"10.1097\/JTO.0b013e31821ea60c","article-title":"Radiation therapy definitions and reporting guidelines for thymic malignancies","volume":"6","author":"Gomez","year":"2011","journal-title":"J\u00a0Thorac Oncol"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib26","doi-asserted-by":"crossref","first-page":"330","DOI":"10.3389\/fonc.2013.00330","article-title":"Radiotherapy for thymic carcinoma: adjuvant, inductive, and definitive","volume":"3","author":"Komaki","year":"2014","journal-title":"Front Oncol"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib27","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1097\/JTO.0000000000000619","article-title":"Role of postoperative radiotherapy in nonlocalized thymoma: propensity-matched analysis of Surveillance, Epidemiology, and End Results database","volume":"10","author":"Lim","year":"2015","journal-title":"J\u00a0Thorac Oncol"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib28","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1016\/j.ijrobp.2016.01.007","article-title":"Survival impact of adjuvant radiation therapy in Masaoka stage II to IV thymomas: a systematic review and meta-analysis","volume":"94","author":"Lim","year":"2016","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib29","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.athoracsur.2015.06.034","article-title":"The effectiveness of postoperative radiotherapy in patients with completely resected thymoma: a meta-analysis","volume":"101","author":"Zhou","year":"2016","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib30","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1016\/j.jtho.2016.06.011","article-title":"Postoperative radiation therapy is associated with longer overall survival in completely resected stage II and III thymoma\u2014an analysis of the International Thymic Malignancies Interest Group retrospective database","volume":"11","author":"Rimner","year":"2016","journal-title":"J\u00a0Thorac Oncol"},{"key":"10.1016\/j.athoracsur.2016.12.042_bib31","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.athoracsur.2012.02.092","article-title":"The role of surgical management in recurrent thymic tumors","volume":"94","author":"Hamaji","year":"2012","journal-title":"Ann Thorac Surg"}],"container-title":["The Annals of Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003497517300152?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003497517300152?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T03:45:45Z","timestamp":1757735145000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003497517300152"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["S0003497517300152"],"URL":"https:\/\/doi.org\/10.1016\/j.athoracsur.2016.12.042","relation":{},"ISSN":["0003-4975"],"issn-type":[{"value":"0003-4975","type":"print"}],"subject":[],"published":{"date-parts":[[2017,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Meta-Analysis of Postoperative Radiotherapy for Thymic Carcinoma","name":"articletitle","label":"Article Title"},{"value":"The Annals of Thoracic Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.athoracsur.2016.12.042","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 by The Society of Thoracic Surgeons Published by Elsevier","name":"copyright","label":"Copyright"}]}}