{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T17:31:12Z","timestamp":1783013472889,"version":"3.54.6"},"reference-count":30,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["annalsthoracicsurgery.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Annals of Thoracic Surgery"],"published-print":{"date-parts":[[2022,7]]},"DOI":"10.1016\/j.athoracsur.2021.06.070","type":"journal-article","created":{"date-parts":[[2021,7,30]],"date-time":"2021-07-30T01:58:45Z","timestamp":1627610325000},"page":"241-247","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["A Structured Program Maximizes Benefit of Lung Cancer Screening in an Area of Endemic Histoplasmosis"],"prefix":"10.1016","volume":"114","author":[{"given":"James A.","family":"Miller","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Tatakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert M.","family":"Van Haren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sangita","family":"Kapur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peterson","family":"Pathrose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mona","family":"Hemingway","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra L.","family":"Starnes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.athoracsur.2021.06.070_bib1","first-page":"7","article-title":"Cancer statistics, 2020","volume":"70","author":"Siegel","year":"2020","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib2","unstructured":"Howlader N, Noone A, Krapcho M, et\u00a0al, eds. SEER Cancer Statistics Review, 1975-2017. National Cancer Institute; 2020, based on November 2019 SEER data submission, posted to the SEER website, April 2020. https:\/\/seer.cancer.gov\/csr\/1975_2017. Accessed October 1, 2020."},{"key":"10.1016\/j.athoracsur.2021.06.070_bib3","doi-asserted-by":"crossref","first-page":"5007","DOI":"10.1002\/cncr.24545","article-title":"Randomized controlled trials of the efficacy of lung cancer screening by sputum cytology revisited: a combined mortality analysis from the Johns Hopkins Lung Project and the Memorial Sloan-Kettering Lung Study","volume":"115","author":"Doria-Rose","year":"2009","journal-title":"Cancer"},{"issue":"suppl","key":"10.1016\/j.athoracsur.2021.06.070_bib4","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1002\/1097-0142(19910215)67:4+<1155::AID-CNCR2820671509>3.0.CO;2-0","article-title":"Screening for lung cancer. A critique of the Mayo Lung Project","volume":"67","author":"Fontana","year":"1991","journal-title":"Cancer"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib5","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1001\/jama.2011.1591","article-title":"Screening by chest radiograph and lung cancer mortality: the Prostate, Lung, Colorectal, and Ovarian (PLCO) randomized trial","volume":"306","author":"Oken","year":"2011","journal-title":"JAMA"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib6","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1056\/NEJMoa1102873","article-title":"Reduced lung-cancer mortality with low-dose computed tomographic screening","volume":"365","author":"Aberle","year":"2011","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib7","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1056\/NEJMoa1911793","article-title":"Reduced lung-cancer mortality with volume CT screening in a randomized trial","volume":"382","author":"de Koning","year":"2020","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib8","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.1016\/j.jtho.2019.05.044","article-title":"Lung cancer incidence and mortality with extended follow-up in the National Lung Screening Trial","volume":"14","year":"2019","journal-title":"J\u00a0Thorac Oncol"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib9","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.rmed.2016.01.021","article-title":"Thoracic lymphadenopathy in benign diseases: a state of the art review","volume":"112","author":"Nin","year":"2016","journal-title":"Respi Med"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib10","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1055\/s-0039-1698429","article-title":"Current concepts in the epidemiology, diagnosis, and management of histoplasmosis syndromes","volume":"41","author":"Azar","year":"2020","journal-title":"Semin Respir Crit Care Med"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib12","series-title":"Non-Small Cell Lung Cancer (NCCN Guidelines Version 8.2020)","year":"2020"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib13","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1158\/1055-9965.EPI-12-0343","article-title":"Use of lung cancer screening tests in the United States: results from the 2010 National Health Interview Survey","volume":"21","author":"Doria-Rose","year":"2012","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib14","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1001\/jamaoncol.2016.6416","article-title":"Lung cancer screening with low-dose computed tomography in the United States\u20142010 to 2015","volume":"3","author":"Jemal","year":"2017","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib15","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.amepre.2019.03.015","article-title":"Lung cancer screening utilization: a behavioral risk factor surveillance system analysis","volume":"57","author":"Zahnd","year":"2019","journal-title":"Am J Prev Med"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib16","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1158\/1055-9965.EPI-14-1241","article-title":"Low-dose CT lung cancer screening practices and attitudes among primary care providers at an academic medical center","volume":"24","author":"Lewis","year":"2015","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib17","doi-asserted-by":"crossref","first-page":"485","DOI":"10.7326\/M14-2086","article-title":"Performance of Lung-RADS in the National Lung Screening Trial: a retrospective assessment","volume":"162","author":"Pinsky","year":"2015","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib18","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1016\/j.jtcvs.2020.08.109","article-title":"Surgery and invasive diagnostic procedures for benign disease are rare in a large low-dose computed tomography lung cancer screening program","volume":"161","author":"Ho","year":"2021","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib19","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1016\/j.jtcvs.2010.08.045","article-title":"Can lung cancer screening by computed tomography be effective in areas with endemic histoplasmosis?","volume":"141","author":"Starnes","year":"2011","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib20","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1513\/AnnalsATS.201602-091OC","article-title":"Factors associated with a positive baseline screening exam result in the National Lung Screening Trial","volume":"13","author":"Balekian","year":"2016","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib21","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1148\/radiol.2481071446","article-title":"Estimating long-term effectiveness of lung cancer screening in the Mayo CT screening study","volume":"248","author":"McMahon","year":"2008","journal-title":"Radiology"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib22","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S0169-5002(02)00023-5","article-title":"FDG-PET imaging and the diagnosis of non-small cell lung cancer in a region of high histoplasmosis prevalence","volume":"36","author":"Croft","year":"2002","journal-title":"Lung Cancer"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib23","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1186\/s12880-020-00469-0","article-title":"Utility of FDG PET\/CT for assessment of lung nodules identified during low dose computed tomography screening","volume":"20","author":"Hadique","year":"2020","journal-title":"BMC Med Imaging"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib24","series-title":"Lung Cancer Screening (NCCN Guidelines Version 1.2021)","year":"2021"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib25","doi-asserted-by":"crossref","first-page":"108774","DOI":"10.1016\/j.ejrad.2019.108774","article-title":"Artificial intelligence applications for thoracic imaging","volume":"123","author":"Chassagnon","year":"2020","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib26","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1038\/s41591-019-0447-x","article-title":"End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography","volume":"25","author":"Ardila","year":"2019","journal-title":"Nat Med"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib27","doi-asserted-by":"crossref","first-page":"979","DOI":"10.21037\/tlcr.2019.12.19","article-title":"Differentiation of non-small cell lung cancer and histoplasmosis pulmonary nodules: insights from radiomics model performance compared with clinician observers","volume":"8","author":"Uthoff","year":"2019","journal-title":"Transl Lung Cancer Res"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib28","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.jtho.2018.11.023","article-title":"Biomarkers in lung cancer screening: achievements, promises, and challenges","volume":"14","author":"Seijo","year":"2019","journal-title":"J\u00a0Thorac Oncol"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib29","first-page":"67","article-title":"Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients","volume":"59","author":"Esteller","year":"1999","journal-title":"Cancer Res"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib30","doi-asserted-by":"crossref","first-page":"1998","DOI":"10.1158\/1078-0432.CCR-16-1371","article-title":"Early detection of lung cancer using DNA promoter hypermethylation in plasma and sputum","volume":"23","author":"Hulbert","year":"2017","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.athoracsur.2021.06.070_bib31","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.athoracsur.2020.05.101","article-title":"Validation of histoplasmosis enzyme immunoassay to evaluate suspicious lung nodules","volume":"111","author":"Shipe","year":"2021","journal-title":"Ann Thorac Surg"}],"container-title":["The Annals of Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003497521013011?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003497521013011?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T04:13:02Z","timestamp":1757736782000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003497521013011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["S0003497521013011"],"URL":"https:\/\/doi.org\/10.1016\/j.athoracsur.2021.06.070","relation":{},"ISSN":["0003-4975"],"issn-type":[{"value":"0003-4975","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Structured Program Maximizes Benefit of Lung Cancer Screening in an Area of Endemic Histoplasmosis","name":"articletitle","label":"Article Title"},{"value":"The Annals of Thoracic Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.athoracsur.2021.06.070","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 by The Society of Thoracic Surgeons","name":"copyright","label":"Copyright"}]}}