{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T06:34:34Z","timestamp":1773124474187,"version":"3.50.1"},"reference-count":28,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["annalsthoracicsurgery.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Annals of Thoracic Surgery"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1016\/j.athoracsur.2021.09.077","type":"journal-article","created":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T01:39:21Z","timestamp":1637545161000},"page":"1679-1687","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["Mitral Annular Calcification in Obstructive Hypertrophic Cardiomyopathy: Prevalence and Outcomes"],"prefix":"10.1016","volume":"114","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7952-0217","authenticated-orcid":false,"given":"Sri Harsha","family":"Patlolla","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hartzell V.","family":"Schaff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rick A.","family":"Nishimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey B.","family":"Geske","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian D.","family":"Lahr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander T.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mackram F.","family":"Eleid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steve R.","family":"Ommen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph A.","family":"Dearani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.athoracsur.2021.09.077_bib1","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/j.ahj.2004.05.048","article-title":"Epidemiology of mitral annular calcification and its predictive value for coronary events in African Americans: the Jackson Cohort of the Atherosclerotic Risk in Communities Study","volume":"148","author":"Fox","year":"2004","journal-title":"Am Heart J"},{"key":"10.1016\/j.athoracsur.2021.09.077_bib2","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/j.jtcvs.2018.05.099","article-title":"Current and evolving strategies in the management of severe mitral annular calcification","volume":"157","author":"Bedeir","year":"2019","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"key":"10.1016\/j.athoracsur.2021.09.077_bib3","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1161\/01.CIR.0000058168.26163.BC","article-title":"Mitral annular calcification predicts cardiovascular morbidity and mortality","volume":"107","author":"Fox","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.athoracsur.2021.09.077_bib4","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1161\/CIRCULATIONAHA.105.552844","article-title":"Mitral and aortic annular calcification are highly associated with systemic calcified atherosclerosis","volume":"113","author":"Allison","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.athoracsur.2021.09.077_bib5","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1016\/S0002-9149(98)00596-7","article-title":"Mitral annular calcium detected by transthoracic echocardiography is a marker for high prevalence and severity of coronary artery disease in patients undergoing coronary angiography","volume":"82","author":"Adler","year":"1998","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.athoracsur.2021.09.077_bib6","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1093\/ndt\/gfn544","article-title":"Association of renal function with cardiac calcifications in older adults: the cardiovascular health study","volume":"24","author":"Asselbergs","year":"2009","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.athoracsur.2021.09.077_bib7","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1016\/j.amjcard.2004.11.025","article-title":"Prevalence of valve calcium and association of valve calcium with coronary artery disease, atherosclerotic vascular disease, and all-cause mortality in 137 patients undergoing hemodialysis for chronic renal failure","volume":"95","author":"Varma","year":"2005","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.athoracsur.2021.09.077_bib8","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1093\/ehjci\/jex093","article-title":"Mitral annular calcification progression and the risk of atrial fibrillation: results from MESA","volume":"19","author":"O\u2019Neal","year":"2018","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.athoracsur.2021.09.077_bib9","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1093\/europace\/euu265","article-title":"Mitral annular calcification and incident atrial fibrillation in the Multi-Ethnic Study of Atherosclerosis","volume":"17","author":"O\u2019Neal","year":"2015","journal-title":"Europace"},{"key":"10.1016\/j.athoracsur.2021.09.077_bib10","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1056\/NEJM199208063270602","article-title":"Mitral annular calcification and the risk of stroke in an elderly cohort","volume":"327","author":"Benjamin","year":"1992","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.athoracsur.2021.09.077_bib11","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.athoracsur.2018.07.098","article-title":"Does mitral valve calcium in patients undergoing mitral valve replacement portend worse survival?","volume":"107","author":"Saran","year":"2019","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.athoracsur.2021.09.077_bib12","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1016\/j.amjcard.2014.03.013","article-title":"Prevalence of calcification of the mitral valve annulus in patients undergoing surgical repair of mitral valve prolapse","volume":"113","author":"Fusini","year":"2014","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.athoracsur.2021.09.077_bib13","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/j.jcmg.2011.12.025","article-title":"Associations of LV hypertrophy with prevalent and incident valve calcification: Multi-Ethnic Study of Atherosclerosis","volume":"5","author":"Elmariah","year":"2012","journal-title":"J\u00a0Am Coll Cardiol Img"},{"key":"10.1016\/j.athoracsur.2021.09.077_bib14","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.ahj.2012.05.014","article-title":"Anatomy, mechanics, and pathophysiology of the mitral annulus","volume":"164","author":"Silbiger","year":"2012","journal-title":"Am Heart J"},{"issue":"17","key":"10.1016\/j.athoracsur.2021.09.077_bib15","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.1016\/j.jacc.2015.08.872","article-title":"Mitral annulus calcification","volume":"66","author":"Abramowitz","year":"2015","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"4","key":"10.1016\/j.athoracsur.2021.09.077_bib16","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1016\/S0022-5223(96)70332-X","article-title":"Extensive calcification of the mitral valve anulus: pathology and surgical management","volume":"111","author":"Carpentier","year":"1996","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"issue":"6","key":"10.1016\/j.athoracsur.2021.09.077_bib17","doi-asserted-by":"crossref","first-page":"939","DOI":"10.7326\/0003-4819-77-6-939","article-title":"Mitral valvular disease. A clinicopathologic survey of the conditions causing the mitral valve to function abnormally","volume":"77","author":"Roberts","year":"1972","journal-title":"Ann Intern Med"},{"issue":"10","key":"10.1016\/j.athoracsur.2021.09.077_bib18","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/0002-9149(87)91040-X","article-title":"Frequency and significance of mitral anular calcium in hypertrophic cardiomyopathy: analysis of 200 necropsy patients","volume":"60","author":"Motamed","year":"1987","journal-title":"Am J Cardiol"},{"issue":"15","key":"10.1016\/j.athoracsur.2021.09.077_bib19","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1016\/0002-9149(87)90938-6","article-title":"Echocardiographic and electrocardiographic characteristics of patients with hypertrophic cardiomyopathy with and without mitral anular calcium","volume":"59","author":"Nair","year":"1987","journal-title":"Am J Cardiol"},{"issue":"6","key":"10.1016\/j.athoracsur.2021.09.077_bib20","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1378\/chest.94.6.1295","article-title":"Prevalence of hypertrophic cardiomyopathy and its association with mitral anular calcium in elderly patients","volume":"94","author":"Aronow","year":"1988","journal-title":"Chest"},{"issue":"11","key":"10.1016\/j.athoracsur.2021.09.077_bib21","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1016\/j.jcmg.2016.09.001","article-title":"Severe mitral annular calcification: multimodality imaging for therapeutic strategies and interventions","volume":"9","author":"Eleid","year":"2016","journal-title":"J\u00a0Am Coll Cardiol Img"},{"issue":"16","key":"10.1016\/j.athoracsur.2021.09.077_bib23","first-page":"1194","article-title":"Concomitant mitral annular calcification and severe aortic stenosis: prevalence, characteristics and outcome following transcatheter aortic valve replacement","volume":"38","author":"Abramowitz","year":"2017","journal-title":"Eur Heart J"},{"issue":"1","key":"10.1016\/j.athoracsur.2021.09.077_bib24","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/0002-9149(78)90986-4","article-title":"Mitral ring calcification in idiopathic hypertrophic subaortic stenosis","volume":"42","author":"Kronzon","year":"1978","journal-title":"Am J Cardiol"},{"issue":"14","key":"10.1016\/j.athoracsur.2021.09.077_bib25","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1016\/j.jacc.2016.07.735","article-title":"Mitral regurgitation in patients with hypertrophic obstructive cardiomyopathy: implications for concomitant valve procedures","volume":"68","author":"Hong","year":"2016","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"7","key":"10.1016\/j.athoracsur.2021.09.077_bib26","doi-asserted-by":"crossref","first-page":"2219","DOI":"10.1016\/S0735-1097(00)01019-6","article-title":"Mitral regurgitation in hypertrophic obstructive cardiomyopathy: relationship to obstruction and relief with myectomy","volume":"36","author":"Yu","year":"2000","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"4","key":"10.1016\/j.athoracsur.2021.09.077_bib27","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1016\/j.jtcvs.2015.11.048","article-title":"Mitral stenosis and hypertrophic obstructive cardiomyopathy: an unusual combination","volume":"151","author":"Hong","year":"2016","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"issue":"2","key":"10.1016\/j.athoracsur.2021.09.077_bib28","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1097\/HCO.0000000000000718","article-title":"Surgical management of mitral annular calcification","volume":"35","author":"El-Eshmawi","year":"2020","journal-title":"Curr Opin Cardiol"},{"issue":"7","key":"10.1016\/j.athoracsur.2021.09.077_bib29","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1161\/CIRCULATIONAHA.119.040095","article-title":"Complexity of defining severe \u201cstenosis\u201d from mitral annular calcification","volume":"140","author":"Reddy","year":"2019","journal-title":"Circulation"}],"container-title":["The Annals of Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003497521019706?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003497521019706?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T04:15:08Z","timestamp":1757736908000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003497521019706"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["S0003497521019706"],"URL":"https:\/\/doi.org\/10.1016\/j.athoracsur.2021.09.077","relation":{},"ISSN":["0003-4975"],"issn-type":[{"value":"0003-4975","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mitral Annular Calcification in Obstructive Hypertrophic Cardiomyopathy: Prevalence and Outcomes","name":"articletitle","label":"Article Title"},{"value":"The Annals of Thoracic Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.athoracsur.2021.09.077","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 by The Society of Thoracic Surgeons","name":"copyright","label":"Copyright"}]}}