{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T21:39:40Z","timestamp":1793137180483,"version":"4.5.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100014555","name":"Murdoch Children's Research Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014555","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["GNT1168270"],"award-info":[{"award-number":["GNT1168270"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005646","name":"Actelion Pharmaceuticals","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005646","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["annalsthoracicsurgery.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Annals of Thoracic Surgery"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.1016\/j.athoracsur.2022.06.018","type":"journal-article","created":{"date-parts":[[2022,7,2]],"date-time":"2022-07-02T01:53:35Z","timestamp":1656726815000},"page":"664-670","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Liver Cirrhosis After the Fontan Procedure: Impact of Atrioventricular Valve Failure"],"prefix":"10.1016","volume":"115","author":[{"given":"Thomas G.","family":"Wilson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay J.","family":"Iyengar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominica","family":"Zentner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Zannino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"d\u2019Udekem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor E.","family":"Konstantinov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.athoracsur.2022.06.018_bib1","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1136\/thx.26.3.240","article-title":"Surgical repair of tricuspid atresia","volume":"26","author":"Fontan","year":"1971","journal-title":"Thorax"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib2","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.jtcvs.2013.09.074","article-title":"Trends in Fontan surgery and risk factors for early adverse outcomes after Fontan surgery: the Australia and New Zealand Fontan Registry experience","volume":"148","author":"Iyengar","year":"2014","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib3","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.ijcard.2016.05.035","article-title":"The Fontan epidemic: population projections from the Australia and New Zealand Fontan Registry","volume":"219","author":"Schilling","year":"2016","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib4","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1017\/S1047951113001650","article-title":"End-organ consequences of the Fontan operation: liver fibrosis, protein-losing enteropathy and plastic bronchitis","volume":"23","author":"Rychik","year":"2013","journal-title":"Cardiol Young"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib5","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.ijcard.2017.11.118","article-title":"Chronic kidney damage in the adult Fontan population","volume":"257","author":"Lee","year":"2018","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib6","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1053\/pcsu.2002.29716","article-title":"Thromboembolic problems after the Fontan operation","volume":"5","author":"Monagle","year":"2002","journal-title":"Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib7","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1136\/heartjnl-2019-315862","article-title":"Modes of late mortality in patients with a Fontan circulation","volume":"106","author":"Poh","year":"2020","journal-title":"Heart"},{"issue":"5","key":"10.1016\/j.athoracsur.2022.06.018_bib8","doi-asserted-by":"crossref","first-page":"e004809","DOI":"10.1161\/JAHA.116.004809","article-title":"Hepatic fibrosis Is universal following Fontan operation, and severity is associated with time from surgery: a liver biopsy and hemodynamic study","volume":"6","author":"Goldberg","year":"2017","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib9","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1161\/CIRCULATIONAHA.117.032717","article-title":"Hepatocellular carcinoma after Fontan operation","volume":"138","author":"Egbe","year":"2018","journal-title":"Circulation"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib10","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.xjtc.2020.03.008","article-title":"Prevalence of hepatocellular carcinoma in the entire Fontan population of Australia and New Zealand","volume":"2","author":"Wilson","year":"2020","journal-title":"JTCVS Tech"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib11","doi-asserted-by":"crossref","first-page":"e234","DOI":"10.1161\/CIR.0000000000000696","article-title":"Evaluation and management of the child and adult with Fontan circulation: a scientific statement from the American Heart Association","volume":"140","author":"Rychik","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib12","first-page":"223","article-title":"Fontan-associated liver disease: a review","volume":"74","author":"Gordon-Walker","year":"2019","journal-title":"J\u00a0Cardiol"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib13","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.hlc.2019.09.010","article-title":"Management of people with a Fontan circulation: a Cardiac Society of Australia and New Zealand Position statement","volume":"29","author":"Zentner","year":"2020","journal-title":"Heart Lung Circ"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib14","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1111\/imj.12318","article-title":"The Australia and New Zealand Fontan Registry: description and initial results from the first population-based Fontan registry","volume":"44","author":"Iyengar","year":"2014","journal-title":"Intern Med J"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib15","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1002\/lt.20906","article-title":"MELD-XI: a rational approach to \u201csickest first\u201d liver transplantation in cirrhotic patients requiring anticoagulant therapy","volume":"13","author":"Heuman","year":"2007","journal-title":"Liver Transplant"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib16","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1161\/CIRCULATIONAHA.120.045597","article-title":"Fontan-associated liver disease","volume":"142","author":"Emamaullee","year":"2020","journal-title":"Circulation"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib17","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1111\/chd.12345","article-title":"Catheter-measured hemodynamics of adult Fontan circulation: associations with adverse event and end-organ dysfunctions","volume":"11","author":"Mori","year":"2016","journal-title":"Congenit Heart Dis"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib18","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1111\/chd.12770","article-title":"Evaluation of Fontan liver disease: correlation of transjugular liver biopsy with magnetic resonance and hemodynamics","volume":"14","author":"Silva-Sepulveda","year":"2019","journal-title":"Congenit Heart Dis"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib19","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1111\/chd.12468","article-title":"Predicting long-term mortality after Fontan procedures: a risk score based on 6707 patients from 28 studies","volume":"12","author":"Alsaied","year":"2017","journal-title":"Congenit Heart Dis"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib20","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1016\/j.jacc.2015.07.065","article-title":"40-year follow-up after the Fontan operation: long-term outcomes of 1,052 patients","volume":"66","author":"Pundi","year":"2015","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"18","key":"10.1016\/j.athoracsur.2022.06.018_bib21","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1016\/j.jacc.2022.02.022","article-title":"Natural and modified history of atrioventricular valve regurgitation in patients with Fontan circulation","volume":"79","author":"King","year":"2022","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib22","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/j.jacc.2018.12.025","article-title":"Atrioventricular valve failure in Fontan palliation","volume":"73","author":"King","year":"2019","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib23","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1016\/j.jtcvs.2016.07.073","article-title":"Long-term outcomes after first-onset arrhythmia in Fontan physiology","volume":"152","author":"Carins","year":"2016","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib24","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.amjcard.2015.11.014","article-title":"Liver disease in patients after the Fontan operation","volume":"117","author":"Pundi","year":"2016","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib25","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.1136\/hrt.2010.201772","article-title":"Late hepatic complications after Fontan operation; non-invasive markers of hepatic fibrosis and risk factors","volume":"96","author":"Baek","year":"2010","journal-title":"Heart"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib26","doi-asserted-by":"crossref","first-page":"S32","DOI":"10.1161\/CIRCULATIONAHA.113.007764","article-title":"Redefining expectations of long-term survival after the Fontan procedure","volume":"130","author":"d\u2019Udekem","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib27","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1093\/icvts\/ivy219","article-title":"In patients undergoing Fontan completion, does a younger age at operation result in better long-term exercise capacity and prognosis?","volume":"28","author":"Daley","year":"2018","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib28","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1093\/eurheartj\/ehy620","article-title":"The clinical spectrum of Fontan-associated liver disease: results from a prospective multimodality screening cohort","volume":"40","author":"Munsterman","year":"2018","journal-title":"Eur Heart J"},{"key":"10.1016\/j.athoracsur.2022.06.018_bib29","doi-asserted-by":"crossref","first-page":"e026087","DOI":"10.1161\/JAHA.122.026087","article-title":"Impact of Fontan fenestration on long-term outcomes: a propensity score-matched analysis","volume":"11","author":"Daley","year":"2022","journal-title":"J Am Heart Assoc"}],"container-title":["The Annals of Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003497522009249?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003497522009249?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T04:15:43Z","timestamp":1757736943000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003497522009249"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["S0003497522009249"],"URL":"https:\/\/doi.org\/10.1016\/j.athoracsur.2022.06.018","relation":{},"ISSN":["0003-4975"],"issn-type":[{"value":"0003-4975","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Liver Cirrhosis After the Fontan Procedure: Impact of Atrioventricular Valve Failure","name":"articletitle","label":"Article Title"},{"value":"The Annals of Thoracic Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.athoracsur.2022.06.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Published by Elsevier Inc. on behalf of The Society of Thoracic Surgeons","name":"copyright","label":"Copyright"}]}}