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Physiol."},{"key":"10.1016\/j.autneu.2015.04.004_bb0400","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1111\/j.1476-5381.1993.tb13593.x","article-title":"Functional importance of cholinergic and purinergic neurotransmission for micturition contraction in the normal, unanaesthetized rat","volume":"109","author":"Igawa","year":"1993","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.autneu.2015.04.004_bb0405","doi-asserted-by":"crossref","first-page":"F245","DOI":"10.1152\/ajprenal.0038.2001","article-title":"P2 receptor-mediated afferent arteriolar vasoconstriction during calcium blockade","volume":"282","author":"Inscho","year":"2001","journal-title":"Am. J. Physiol. 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Res."},{"key":"10.1016\/j.autneu.2015.04.004_bb0440","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1038\/nature08198","article-title":"Crystal structure of the ATP-gated P2X4 ion channel in the closed state","volume":"460","author":"Kawate","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.autneu.2015.04.004_bb0445","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/S0165-6147(00)89010-0","article-title":"How should P2X-purinoceptors be characterised pharmacologically?","volume":"16","author":"Kennedy","year":"1995","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.autneu.2015.04.004_bb0450","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/0014-2999(86)90409-7","article-title":"The contributions of noradrenaline and ATP to the responses of the rabbit central ear artery to sympathetic nerve stimulation depend on the parameters of stimulation","volume":"122","author":"Kennedy","year":"1986","journal-title":"Eur. J. 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A."},{"key":"10.1016\/j.autneu.2015.04.004_bb0615","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1038\/sj.bjp.0700157","article-title":"The signalling pathway which causes contraction via P2-purinoceptors in rat urinary bladder smooth muscle","volume":"122","author":"Naramatsu","year":"1997","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.autneu.2015.04.004_bb0620","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1111\/j.1471-4159.2004.02939.x","article-title":"Biochemical and functional evidence for heteromeric assembly of P2X1 and P2X4 subunits","volume":"92","author":"Nicke","year":"2005","journal-title":"J. Neurochem."},{"key":"10.1016\/j.autneu.2015.04.004_bb0625","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0022-5347(05)65403-1","article-title":"P2X receptors and their role in female idiopathic detrusor instability","volume":"167","author":"O'Reilly","year":"2002","journal-title":"J. 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