{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T03:32:58Z","timestamp":1791343978425,"version":"4.3.1"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["autonomicneuroscience.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Autonomic Neuroscience"],"published-print":{"date-parts":[[2016,1]]},"DOI":"10.1016\/j.autneu.2015.12.007","type":"journal-article","created":{"date-parts":[[2015,12,29]],"date-time":"2015-12-29T02:45:15Z","timestamp":1451357115000},"page":"26-31","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Assessment of cardiac autonomic tone in conscious rats"],"prefix":"10.1016","volume":"194","author":[{"given":"Halil","family":"Sayin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Chapuis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Chevalier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Barr\u00e8s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claude","family":"Julien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.autneu.2015.12.007_bb0005","doi-asserted-by":"crossref","first-page":"R1074","DOI":"10.1152\/ajpregu.00270.2005","article-title":"Differential responses of frequency components of renal sympathetic nerve activity to arterial pressure changes in conscious rats","volume":"289","author":"Bertram","year":"2005","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.autneu.2015.12.007_bb0010","doi-asserted-by":"crossref","first-page":"26","DOI":"10.3389\/fphys.2013.00026","article-title":"The LF\/HF ratio does not accurately measure cardiac sympatho-vagal balance","volume":"4","author":"Billman","year":"2013","journal-title":"Front. Physiol."},{"key":"10.1016\/j.autneu.2015.12.007_bb0015","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1111\/1440-1681.12121","article-title":"Cholinergic stimulation with pyridostigmine improves autonomic function in infarcted rats","volume":"40","author":"de La Fuente","year":"2013","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.autneu.2015.12.007_bb0020","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1161\/CIRCRESAHA.116.304493","article-title":"Sudden cardiac death risk stratification","volume":"116","author":"Deyell","year":"2015","journal-title":"Circ. Res."},{"key":"10.1016\/j.autneu.2015.12.007_bb0025","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/S1566-0702(01)00365-4","article-title":"Intravenous amiodarone modifies autonomic balance and increases baroreflex sensitivity in conscious rats","volume":"95","author":"Dias da Silva","year":"2002","journal-title":"Auton. Neurosci."},{"key":"10.1016\/j.autneu.2015.12.007_bb0030","doi-asserted-by":"crossref","first-page":"3224","DOI":"10.1161\/01.CIR.96.9.3224","article-title":"Sympathovagal balance: a critical appraisal","volume":"96","author":"Eckberg","year":"1997","journal-title":"Circulation"},{"key":"10.1016\/j.autneu.2015.12.007_bb0035","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1111\/j.1472-8206.2007.00502.x","article-title":"Sympathetic control of short-term heart rate variability and its pharmacological modulation","volume":"21","author":"Elghozi","year":"2007","journal-title":"Fundam. Clin. Pharmacol."},{"key":"10.1016\/j.autneu.2015.12.007_bb0040","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.1093\/eurheartj\/ehv087","article-title":"The sympathetic\/parasympathetic imbalance in heart failure with reduced ejection fraction","volume":"36","author":"Floras","year":"2015","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.autneu.2015.12.007_bb0045","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1007\/s13239-013-0150-x","article-title":"Automatic atrial arrhythmia detection based on RR interval analysis in conscious rats","volume":"4","author":"Gallet","year":"2013","journal-title":"Cardiovasc. Eng. Technol."},{"key":"10.1016\/j.autneu.2015.12.007_bb0050","first-page":"H1273","article-title":"Sympathovagal balance: how should we measure it?","volume":"276","author":"Goldberger","year":"1999","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.autneu.2015.12.007_bb0055","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.jacc.2013.01.091","article-title":"Atrial fibrillation promotion by endurance exercise: demonstration and mechanistic exploration in an animal model","volume":"62","author":"Guasch","year":"2013","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.autneu.2015.12.007_bb0060","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0165-1838(90)90132-3","article-title":"Spectral analysis of blood pressure and heart rate in conscious rats: effects of autonomic blockers","volume":"30","author":"Japundzic","year":"1990","journal-title":"J. Auton. Nerv. Syst."},{"key":"10.1016\/j.autneu.2015.12.007_bb0065","series-title":"Clinical Investigation and Statistics in Laboratory Medicine","author":"Jones","year":"1997"},{"key":"10.1016\/j.autneu.2015.12.007_bb0070","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.cardiores.2005.11.008","article-title":"The enigma of Mayer waves: facts and models","volume":"70","author":"Julien","year":"2006","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.autneu.2015.12.007_bb0075","first-page":"88","article-title":"Changes in hypothalamic and body temperatures during 24hours in rats","volume":"53","author":"Kaushik","year":"2009","journal-title":"Indian J. Physiol. Pharmacol."},{"key":"10.1016\/j.autneu.2015.12.007_bb0080","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.autneu.2004.11.007","article-title":"Cardiovascular and autonomic nervous functions during acclimatization to hypoxia in conscious rats","volume":"117","author":"Kawaguchi","year":"2005","journal-title":"Auton. Neurosci."},{"key":"10.1016\/j.autneu.2015.12.007_bb0085","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1152\/ajpregu.00102.2013","article-title":"Increase in parasympathetic tone by pyridostigmine prevents ventricular dysfunction during the onset of heart failure","volume":"305","author":"Lataro","year":"2013","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.autneu.2015.12.007_bb0090","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1111\/j.1469-7793.1998.263bx.x","article-title":"Short-term haemodynamic variability in the conscious areflexic rat","volume":"506","author":"L\u00e9tienne","year":"1998","journal-title":"J. Physiol."},{"key":"10.1016\/j.autneu.2015.12.007_bb0095","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1161\/01.RES.29.5.437","article-title":"Sympathetic\u2013parasympathetic interactions in the heart","volume":"29","author":"Levy","year":"1971","journal-title":"Circ. Res."},{"key":"10.1016\/j.autneu.2015.12.007_bb0100","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/S1095-6433(99)00129-4","article-title":"Resting and maximal heart rates in ectothermic vertebrates","volume":"124","author":"Lillywhite","year":"1999","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"key":"10.1016\/j.autneu.2015.12.007_bb0105","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/0165-1838(91)90047-7","article-title":"Pharmacologic responses and spectral analyses of spontaneous fluctuations in heart rate and blood pressure in SHR rats","volume":"36","author":"Murphy","year":"1991","journal-title":"J. Auton. Nerv. Syst."},{"key":"10.1016\/j.autneu.2015.12.007_bb0110","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1097\/00004872-199715040-00011","article-title":"Autonomic control of ultradian and circadian rhythms of blood pressure, heart rate, and baroreflex sensitivity in spontaneously hypertensive rats","volume":"15","author":"Oosting","year":"1997","journal-title":"J. Hypertens."},{"key":"10.1016\/j.autneu.2015.12.007_bb0115","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1161\/01.RES.59.2.178","article-title":"Power spectral analysis of heart rate and arterial pressure variabilities as a marker of sympatho\u2013vagal interaction in man and conscious dog","volume":"59","author":"Pagani","year":"1986","journal-title":"Circ. Res."},{"key":"10.1016\/j.autneu.2015.12.007_bb0120","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1002\/j.2040-4603.2015.tb00626.x","article-title":"Atrial fibrillation: mechanisms, therapeutics, and future directions","volume":"5","author":"Pellman","year":"2015","journal-title":"Compr. Physiol."},{"key":"10.1016\/j.autneu.2015.12.007_bb0125","first-page":"H1729","article-title":"Autonomic and ventilatory components of heart rate and blood pressure variability in freely behaving rats","volume":"269","author":"Perlini","year":"1995","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.autneu.2015.12.007_bb0130","doi-asserted-by":"crossref","first-page":"H1554","DOI":"10.1152\/ajpheart.00256.2015","article-title":"Progressive development of cardiomyopathy following altered autonomic activity in status epilepticus","volume":"309","author":"Read","year":"2015","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.autneu.2015.12.007_bb0135","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/0165-1838(93)90050-5","article-title":"Power spectrum analysis of cardiovascular variability monitored by telemetry in conscious unrestrained rats","volume":"45","author":"Rubini","year":"1993","journal-title":"J. Auton. Nerv. Syst."},{"key":"10.1016\/j.autneu.2015.12.007_bb0140","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.physbeh.2014.05.037","article-title":"Developmental differences in the effects of alcohol and stress on heart rate variability","volume":"135","author":"Saalfield","year":"2014","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.autneu.2015.12.007_bb0145","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1097\/00004872-199816121-00020","article-title":"Autonomic contribution to the blood pressure and heart rate variability changes in early experimental hyperthyroidism","volume":"12","author":"Safa-Tisseront","year":"1998","journal-title":"J. Hypertens."},{"key":"10.1016\/j.autneu.2015.12.007_bb0150","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0304-3940(89)90239-5","article-title":"Characterization of beta 1- and beta 2-adrenoceptor subtypes in the rat sinoatrial node and stellate ganglia by quantitative autoradiography","volume":"96","author":"Saito","year":"1989","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.autneu.2015.12.007_bb0155","doi-asserted-by":"crossref","first-page":"H101","DOI":"10.1152\/ajpheart.00591.2014","article-title":"Cholinergic stimulation with pyridostigmine protects myocardial infarcted rats against ischemic-induced arrhythmias and preserves connexin43 protein","volume":"308","author":"Santos-Almeida","year":"2015","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.autneu.2015.12.007_bb0160","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1111\/1440-1681.12458","article-title":"Pyridostigmine enhances atrial tachyarrhythmias in aging spontaneously hypertensive rats","volume":"42","author":"Sayin","year":"2015","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.autneu.2015.12.007_bb0165","doi-asserted-by":"crossref","first-page":"H386","DOI":"10.1152\/ajpheart.00004.2012","article-title":"Unprovoked atrial tachyarrhythmias in aging spontaneously hypertensive rats: the role of the autonomic nervous system","volume":"303","author":"Scridon","year":"2012","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.autneu.2015.12.007_bb0170","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.atherosclerosis.2014.06.016","article-title":"Blood pressure variability, impaired autonomic function and vascular senescence in aged spontaneously hypertensive rats are ameliorated by angiotensin blockade","volume":"236","author":"Sueta","year":"2014","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.autneu.2015.12.007_bb0175","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/j.yjmcc.2009.08.023","article-title":"Structural remodelling of the sinoatrial node in obese old rats","volume":"48","author":"Yanni","year":"2010","journal-title":"J. Mol. Cell. Cardiol."}],"container-title":["Autonomic Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1566070215300394?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1566070215300394?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T12:07:03Z","timestamp":1761566823000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1566070215300394"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1]]},"references-count":35,"alternative-id":["S1566070215300394"],"URL":"https:\/\/doi.org\/10.1016\/j.autneu.2015.12.007","relation":{},"ISSN":["1566-0702"],"issn-type":[{"value":"1566-0702","type":"print"}],"subject":[],"published":{"date-parts":[[2016,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Assessment of cardiac autonomic tone in conscious rats","name":"articletitle","label":"Article Title"},{"value":"Autonomic Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.autneu.2015.12.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}