{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T22:24:47Z","timestamp":1781216687897,"version":"3.54.1"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008603","name":"Cancer Institute, University of Pittsburgh","doi-asserted-by":"publisher","award":["P30 CA047904"],"award-info":[{"award-number":["P30 CA047904"]}],"id":[{"id":"10.13039\/100008603","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["autonomicneuroscience.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Autonomic Neuroscience"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1016\/j.autneu.2016.06.007","type":"journal-article","created":{"date-parts":[[2016,7,3]],"date-time":"2016-07-03T09:56:56Z","timestamp":1467539816000},"page":"114-121","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Role of the abdominal vagus and hindbrain in inhalational anesthesia-induced vomiting"],"prefix":"10.1016","volume":"202","author":[{"given":"Ragini G.","family":"Gupta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0812-9381","authenticated-orcid":false,"given":"Claire","family":"Schafer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yolande","family":"Ramaroson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael G.","family":"Sciullo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5587-3912","authenticated-orcid":false,"given":"Charles C.","family":"Horn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.autneu.2016.06.007_bb0005","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1139\/y90-047","article-title":"The abdominal visceral innervation and the emetic reflex: pathways, pharmacology, and plasticity","volume":"68","author":"Andrews","year":"1990","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"10.1016\/j.autneu.2016.06.007_bb0010","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1038\/sj.bjp.0703428","article-title":"The emetic and anti-emetic effects of the capsaicin analogue resiniferatoxin in Suncus murinus, the house musk shrew","volume":"130","author":"Andrews","year":"2000","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.autneu.2016.06.007_bb0015","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1093\/bja\/88.5.659","article-title":"Volatile anaesthetics may be the main cause of early but not delayed postoperative vomiting: a randomized controlled trial of factorial design","volume":"88","author":"Apfel","year":"2002","journal-title":"Br. J. Anaesth."},{"key":"10.1016\/j.autneu.2016.06.007_bb0020","doi-asserted-by":"crossref","first-page":"1987","DOI":"10.1016\/j.clinthera.2010.11.014","article-title":"Transdermal scopolamine for the prevention of postoperative nausea and vomiting: a systematic review and meta-analysis","volume":"32","author":"Apfel","year":"2010","journal-title":"Clin. Ther."},{"key":"10.1016\/j.autneu.2016.06.007_bb0025","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1093\/bja\/aes276","article-title":"Evidence-based analysis of risk factors for postoperative nausea and vomiting","volume":"109","author":"Apfel","year":"2012","journal-title":"Br. J. Anaesth."},{"key":"10.1016\/j.autneu.2016.06.007_bb0030","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/BF00178966","article-title":"Topographical distribution of 5-HT3 receptor recognition sites in the ferret brain stem","volume":"342","author":"Barnes","year":"1990","journal-title":"Naunyn Schmiedeberg's Arch. Pharmacol."},{"key":"10.1016\/j.autneu.2016.06.007_bb0035","doi-asserted-by":"crossref","first-page":"4207","DOI":"10.1210\/en.2010-0295","article-title":"A new oxytocin-saporin cytotoxin for lesioning oxytocin-receptive neurons in the rat hindbrain","volume":"151","author":"Baskin","year":"2010","journal-title":"Endocrinology"},{"key":"10.1016\/j.autneu.2016.06.007_bb0040","series-title":"Quantifying Behavior the JWatcher Way","author":"Blumstein","year":"2007"},{"key":"10.1016\/j.autneu.2016.06.007_bb0045","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD004125.pub2","article-title":"Drugs for preventing postoperative nausea and vomiting","author":"Carlisle","year":"2006","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.autneu.2016.06.007_bb0050","doi-asserted-by":"crossref","first-page":"R902","DOI":"10.1152\/ajpregu.90952.2008","article-title":"Chemotherapy agent cisplatin induces 48-h fos expression in the brain of a vomiting species, the house musk shrew (Suncus murinus)","volume":"296","author":"De Jonghe","year":"2009","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.autneu.2016.06.007_bb0055","doi-asserted-by":"crossref","first-page":"R1082","DOI":"10.1152\/ajpregu.00432.2014","article-title":"Catecholaminergic neurons in the comissural region of the nucleus of the solitary tract modulate hyperosmolality-induced responses","volume":"309","author":"Freiria-Oliveira","year":"2015","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.autneu.2016.06.007_bb0060","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/S0952-8180(02)00507-X","article-title":"How much are patients willing to pay to avoid intraoperative awareness?","volume":"15","author":"Gan","year":"2003","journal-title":"J. Clin. Anesth."},{"key":"10.1016\/j.autneu.2016.06.007_bb0065","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1016\/S0028-3908(98)00133-6","article-title":"Inhibition of anaesthetic-induced emesis by a NK1 or 5-HT3 receptor antagonist in the house musk shrew, Suncus murinus","volume":"37","author":"Gardner","year":"1998","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.autneu.2016.06.007_bb0070","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1185\/030079906X104830","article-title":"Postoperative nausea and vomiting following inpatient surgeries in a teaching hospital: a retrospective database analysis","volume":"22","author":"Habib","year":"2006","journal-title":"Curr. Med. Res. Opin."},{"key":"10.1016\/j.autneu.2016.06.007_bb0075","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.appet.2007.09.015","article-title":"Why is the neurobiology of nausea and vomiting so important?","volume":"50","author":"Horn","year":"2008","journal-title":"Appetite"},{"key":"10.1016\/j.autneu.2016.06.007_bb0080","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.autneu.2009.03.008","article-title":"Brain fos expression induced by the chemotherapy agent cisplatin in the rat is partially dependent on an intact abdominal vagus","volume":"148","author":"Horn","year":"2009","journal-title":"Auton. Neurosci."},{"key":"10.1016\/j.autneu.2016.06.007_bb0085","doi-asserted-by":"crossref","first-page":"2703","DOI":"10.2174\/13816128113199990568","article-title":"The medical implications of gastrointestinal vagal afferent pathways in nausea and vomiting","volume":"20","author":"Horn","year":"2014","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.autneu.2016.06.007_bb0090","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.autneu.2006.09.005","article-title":"Brain fos expression during 48h after cisplatin treatment: neural pathways for acute and delayed visceral sickness","volume":"132","author":"Horn","year":"2007","journal-title":"Auton. Neurosci."},{"key":"10.1016\/j.autneu.2016.06.007_bb0095","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.physbeh.2012.03.031","article-title":"Post-anesthesia vomiting: impact of isoflurane and morphine on ferrets and musk shrews","volume":"106","author":"Horn","year":"2012","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.autneu.2016.06.007_bb0100","doi-asserted-by":"crossref","DOI":"10.1371\/annotation\/1c75cd5d-9dde-4ace-8524-a4980745e804","article-title":"Why can't rodents vomit? A comparative behavioral, anatomical, and physiological study","volume":"8","author":"Horn","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.autneu.2016.06.007_bb0105","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.autneu.2013.07.006","article-title":"Novel dynamic measures of emetic behavior in musk shrews","volume":"179","author":"Horn","year":"2013","journal-title":"Auton. Neurosci."},{"key":"10.1016\/j.autneu.2016.06.007_bb0110","doi-asserted-by":"crossref","first-page":"R341","DOI":"10.1152\/ajpregu.00413.2013","article-title":"Delineation of vagal emetic pathways: intragastric copper sulfate-induced emesis and viral tract tracing in musk shrews","volume":"306","author":"Horn","year":"2014","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.autneu.2016.06.007_bb0115","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.ejphar.2013.10.037","article-title":"Pathophysiological and neurochemical mechanisms of postoperative nausea and vomiting","volume":"722","author":"Horn","year":"2014","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.autneu.2016.06.007_bb0120","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.1111\/j.1462-5822.2007.00957.x","article-title":"Staphylococcal enterotoxin induces emesis through increasing serotonin release in intestine and it is downregulated by cannabinoid receptor 1","volume":"9","author":"Hu","year":"2007","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.autneu.2016.06.007_bb0125","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.jneumeth.2011.02.032","article-title":"Computerized detection and analysis of cancer chemotherapy-induced emesis in a small animal model, musk shrew","volume":"197","author":"Huang","year":"2011","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.autneu.2016.06.007_bb0130","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1566-0702(03)00026-2","article-title":"Induction of fos protein in neurons in the medulla oblongata after motion- and X-irradiation-induced emesis in musk shrews (Suncus murinus)","volume":"107","author":"Ito","year":"2003","journal-title":"Auton. Neurosci."},{"key":"10.1016\/j.autneu.2016.06.007_bb0135","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1038\/nbt.2834","article-title":"Virally mediated optogenetic excitation and inhibition of pain in freely moving nontransgenic mice","volume":"32","author":"Iyer","year":"2014","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.autneu.2016.06.007_bb0140","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1097\/00000539-200212000-00028","article-title":"Isoflurane, but not halothane, depresses c-fos expression in rat spinal cord at concentrations that suppress reflex movement after supramaximal noxious stimulation","volume":"95","author":"Jinks","year":"2002","journal-title":"Anesth. Analg."},{"key":"10.1016\/j.autneu.2016.06.007_bb0145","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1007\/BF00178967","article-title":"[3H] GR67330, a very high affinity ligand for 5-HT3 receptors","volume":"342","author":"Kilpatrick","year":"1990","journal-title":"Naunyn Schmiedeberg's Arch. Pharmacol."},{"key":"10.1016\/j.autneu.2016.06.007_bb0150","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1016\/S0022-3565(25)23856-3","article-title":"Alcohols and anesthetics enhance the function of 5-hydroxytryptamine3 receptors expressed in Xenopus laevis oocytes","volume":"271","author":"Machu","year":"1994","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.autneu.2016.06.007_bb0155","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1136\/gut.42.6.875","article-title":"Intractable vomiting due to a brainstem lesion in the absence of neurological signs or raised intracranial pressure","volume":"42","author":"Mann","year":"1998","journal-title":"Gut"},{"key":"10.1016\/j.autneu.2016.06.007_bb0160","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1023\/A:1010939530412","article-title":"Distribution of [3H]GR65630 binding in human brain postmortem","volume":"26","author":"Marazziti","year":"2001","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.autneu.2016.06.007_bb0165","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1006\/frne.1994.1012","article-title":"The area postrema and vomiting","volume":"15","author":"Miller","year":"1994","journal-title":"Front. Neuroendocrinol."},{"key":"10.1016\/j.autneu.2016.06.007_bb0170","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/0006-8993(94)91325-0","article-title":"Brain areas essential or non-essential for emesis","volume":"647","author":"Miller","year":"1994","journal-title":"Brain Res."},{"key":"10.1016\/j.autneu.2016.06.007_bb0175","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1136\/gut.31.5.526","article-title":"Psychogenic vomiting: the relation between patterns of vomiting and psychiatric diagnoses","volume":"31","author":"Muraoka","year":"1990","journal-title":"Gut"},{"key":"10.1016\/j.autneu.2016.06.007_bb0180","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/0165-6147(96)10003-1","article-title":"Allosteric modulation of 5-HT3 receptors: focus on alcohols and anaesthetic agents","volume":"17","author":"Parker","year":"1996","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.autneu.2016.06.007_bb0185","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.yebeh.2015.10.009","article-title":"Ictal vomiting as a sign of temporal lobe epilepsy confirmed by stereo-EEG and surgical outcome","volume":"53","author":"Pietrafusa","year":"2015","journal-title":"Epilepsy Behav."},{"key":"10.1016\/j.autneu.2016.06.007_bb0190","first-page":"R361","article-title":"Retrograde tracer technique for assessment of selective and total subdiaphragmatic vagotomies","volume":"253","author":"Powley","year":"1987","journal-title":"Am. J. Phys."},{"key":"10.1016\/j.autneu.2016.06.007_bb0195","series-title":"Serotonin and the Scientific Basis of Anti-Emetic Therapy Oxford, Philadelphia","author":"Reynolds","year":"1995"},{"key":"10.1016\/j.autneu.2016.06.007_bb0200","first-page":"1533","article-title":"Anticipatory nausea and vomiting","volume":"19","author":"Roscoe","year":"2011","journal-title":"Support Care Cancer"},{"key":"10.1016\/j.autneu.2016.06.007_bb0205","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.1523\/JNEUROSCI.11-08-02321.1991","article-title":"c-fos mRNA, fos, and fos-related antigen induction by hypertonic saline and stress","volume":"11","author":"Sharp","year":"1991","journal-title":"J. Neurosci."},{"key":"10.1016\/j.autneu.2016.06.007_bb0210","first-page":"205","article-title":"Metabolic mapping with cellular resolution: c-fos vs. 2-deoxyglucose","volume":"7","author":"Sharp","year":"1993","journal-title":"Crit. Rev. Neurobiol."},{"key":"10.1016\/j.autneu.2016.06.007_bb0215","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1113\/eph8702424","article-title":"An arterially perfused decerebrate preparation of Suncus murinus (house musk shrew) for the study of emesis and swallowing","volume":"87","author":"Smith","year":"2002","journal-title":"Exp. Physiol."},{"key":"10.1016\/j.autneu.2016.06.007_bb0220","doi-asserted-by":"crossref","first-page":"R1380","DOI":"10.1152\/ajpregu.00361.2011","article-title":"Integrative responses of neurons in nucleus tractus solitarius to visceral afferent stimulation and vestibular stimulation in vertical planes","volume":"301","author":"Sugiyama","year":"2011","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.autneu.2016.06.007_bb0225","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1093\/ilar.45.1.25","article-title":"The musk shrew (Suncus murinus): a model species for studies of nutritional regulation of reproduction","volume":"45","author":"Temple","year":"2004","journal-title":"ILAR J."},{"key":"10.1016\/j.autneu.2016.06.007_bb0230","series-title":"Proceeding of ROC-Japan Symposium on Suncus murinus: New Experimental Animal, its Speciality and Usefulnesss","article-title":"Introduction: A new experimental animal, Suncus murinus","author":"Wang","year":"1994"},{"key":"10.1016\/j.autneu.2016.06.007_bb0235","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/0196-9781(86)90076-8","article-title":"Use of cryoprotectant to maintain long-term peptide immunoreactivity and tissue morphology","volume":"7","author":"Watson","year":"1986","journal-title":"Peptides"},{"key":"10.1016\/j.autneu.2016.06.007_bb0240","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0165-1838(00)00105-3","article-title":"Abdominal vagi mediate c-fos expression induced by X-ray irradiation in the nucleus tractus solitarii of the rat","volume":"83","author":"Yamada","year":"2000","journal-title":"Auton. Neurosci."},{"key":"10.1016\/j.autneu.2016.06.007_bb0245","first-page":"R974","article-title":"Organization of vestibular inputs to nucleus tractus solitarius and adjacent structures in cat brain stem","volume":"267","author":"Yates","year":"1994","journal-title":"Am. J. Phys."},{"key":"10.1016\/j.autneu.2016.06.007_bb0250","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/S0361-9230(98)00092-6","article-title":"Physiological basis and pharmacology of motion sickness: an update","volume":"47","author":"Yates","year":"1998","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.autneu.2016.06.007_bb0255","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1038\/nprot.2009.226","article-title":"Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures","volume":"5","author":"Zhang","year":"2010","journal-title":"Nat. Protoc."}],"container-title":["Autonomic Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1566070216300807?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1566070216300807?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T12:11:17Z","timestamp":1761567077000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1566070216300807"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":51,"alternative-id":["S1566070216300807"],"URL":"https:\/\/doi.org\/10.1016\/j.autneu.2016.06.007","relation":{},"ISSN":["1566-0702"],"issn-type":[{"value":"1566-0702","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of the abdominal vagus and hindbrain in inhalational anesthesia-induced vomiting","name":"articletitle","label":"Article Title"},{"value":"Autonomic Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.autneu.2016.06.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}