{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T20:58:13Z","timestamp":1778273893973,"version":"3.51.4"},"reference-count":99,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["autonomicneuroscience.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Autonomic Neuroscience"],"published-print":{"date-parts":[[2017,5]]},"DOI":"10.1016\/j.autneu.2016.11.002","type":"journal-article","created":{"date-parts":[[2016,11,25]],"date-time":"2016-11-25T04:32:17Z","timestamp":1480048337000},"page":"74-80","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Potential role of endurance training in altering renal sympathetic nerve activity in CKD?"],"prefix":"10.1016","volume":"204","author":[{"given":"Erin J","family":"Howden","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justin S","family":"Lawley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murray","family":"Esler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin D.","family":"Levine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.autneu.2016.11.002_bb0005","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1038\/ki.1991.236","article-title":"Effect of dialysis and renal transplantation on autonomic dysfunction in chronic renal failure","volume":"40","author":"Agarwal","year":"1991","journal-title":"Kidney Int."},{"key":"10.1016\/j.autneu.2016.11.002_bb0010","doi-asserted-by":"crossref","first-page":"2152","DOI":"10.1161\/CIRCULATIONAHA.114.010775","article-title":"Cardiac remodeling in response to 1year of intensive endurance training","volume":"130","author":"Arbab-Zadeh","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.autneu.2016.11.002_bb0015","doi-asserted-by":"crossref","first-page":"2983","DOI":"10.1016\/j.ijcard.2012.08.050","article-title":"Acute exercise induce endothelial nitric oxide synthase phosphorylation via Akt and AMP-activated protein kinase in aorta of rats: Role of reactive oxygen species","volume":"167","author":"Barbosa","year":"2013","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0020","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1093\/ndt\/gft529","article-title":"Randomized controlled trial to evaluate the impact of aerobic exercise on visceral fat in overweight chronic kidney disease patients","volume":"29","author":"Baria","year":"2014","journal-title":"Nephrol. Dial. Transplant."},{"key":"10.1016\/j.autneu.2016.11.002_bb0025","doi-asserted-by":"crossref","first-page":"F1","DOI":"10.1152\/ajprenal.00424.2007","article-title":"Nitric oxide deficiency in chronic kidney disease","volume":"294","author":"Baylis","year":"2008","journal-title":"Am. J. Physiol. Ren. Physiol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0030","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1179\/1351000214Y.0000000114","article-title":"Oxidative stress contributes to muscle atrophy in chronic kidney disease patients","volume":"20","author":"Beetham","year":"2015","journal-title":"Redox Rep."},{"key":"10.1016\/j.autneu.2016.11.002_bb0035","doi-asserted-by":"crossref","DOI":"10.1056\/NEJMoa1402670","article-title":"A controlled trial of renal denervation for resistant hypertension","author":"Bhatt","year":"2014","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.autneu.2016.11.002_bb0040","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1016\/j.jacc.2014.03.062","article-title":"Impact of lifelong exercise \u201cdose\u201d on left ventricular compliance and distensibility","volume":"64","author":"Bhella","year":"2014","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0045","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1161\/01.HYP.36.6.1018","article-title":"Exercise training increases baroreceptor gain sensitivity in normal and hypertensive rats","volume":"36","author":"Brum","year":"2000","journal-title":"Hypertension"},{"key":"10.1016\/j.autneu.2016.11.002_bb0050","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.autneu.2012.10.005","article-title":"Changes in GABAergic inputs in the paraventricular nucleus maintain sympathetic vasomotor tone in chronic heart failure","volume":"171","author":"Carillo","year":"2012","journal-title":"Auton. Neurosci."},{"key":"10.1016\/j.autneu.2016.11.002_bb0055","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.autneu.2014.10.020","article-title":"Sympathetic neural adaptations to exercise training in humans","volume":"188","author":"Carter","year":"2015","journal-title":"Auton. Neurosci."},{"key":"10.1016\/j.autneu.2016.11.002_bb0060","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1542-4758.2009.00403.x","article-title":"Categorization of the hemodynamic response to hemodialysis: the importance of baroreflex sensitivity","volume":"14","author":"Chesterton","year":"2010","journal-title":"Hemodial. Int."},{"key":"10.1016\/j.autneu.2016.11.002_bb0065","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1113\/jphysiol.2012.239566","article-title":"Sprint interval and endurance training are equally effective in increasing muscle microvascular density and eNOS content in sedentary males","volume":"591","author":"Cocks","year":"2013","journal-title":"J. Physiol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0070","doi-asserted-by":"crossref","first-page":"1912","DOI":"10.1056\/NEJM199212313272704","article-title":"Sympathetic overactivity in patients with chronic renal failure","volume":"327","author":"Converse","year":"1992","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.autneu.2016.11.002_bb0075","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1097\/00005768-200206000-00004","article-title":"Effects of exercise training on cardiovagal and sympathetic responses to Valsalva's maneuver","volume":"34","author":"Cooke","year":"2002","journal-title":"Med. Sci. Sports Exerc."},{"key":"10.1016\/j.autneu.2016.11.002_bb0080","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1111\/j.1440-1681.1998.tb02235.x","article-title":"Control of sympathetic outflows by the hypothalamic paraventricular nucleus","volume":"25","author":"Coote","year":"1998","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0085","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.112.004473","article-title":"Exercise training for blood pressure: a systematic review and meta-analysis","volume":"2","author":"Cornelissen","year":"2013","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.autneu.2016.11.002_bb0090","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1113\/expphysiol.2004.029215","article-title":"Dynamic analysis of patterns of renal sympathetic nerve activity: implications for renal function","volume":"90","author":"Dibona","year":"2005","journal-title":"Exp. Physiol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0095","first-page":"H974","article-title":"Exercise training attenuates baroreflex regulation of nerve activity in rabbits","volume":"255","author":"Dicarlo","year":"1988","journal-title":"Am. J. Phys."},{"key":"10.1016\/j.autneu.2016.11.002_bb0100","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1097\/00004872-200309000-00017","article-title":"The sympathetic nervous system in hypertension: assessment by blood pressure variability and ganglionic blockade","volume":"21","author":"Diedrich","year":"2003","journal-title":"J. Hypertens."},{"key":"10.1016\/j.autneu.2016.11.002_bb0105","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1161\/01.HYP.11.1.3","article-title":"Assessment of human sympathetic nervous system activity from measurements of norepinephrine turnover","volume":"11","author":"Esler","year":"1988","journal-title":"Hypertension"},{"issue":"59","key":"10.1016\/j.autneu.2016.11.002_bb0110","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1152\/jappl.1985.59.3.947","article-title":"Plasma levels of renin, angiotensin II, and 6-ketoprostaglandin F1 alpha in endurance athletes","volume":"1985","author":"Fagard","year":"1985","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0115","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1161\/01.HYP.0000158312.63381.c1","article-title":"Persistent sympathetic activation during chronic antihypertensive therapy: a potential mechanism for long term morbidity?","volume":"45","author":"Fu","year":"2005","journal-title":"Hypertension"},{"key":"10.1016\/j.autneu.2016.11.002_bb0120","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1161\/CIRCULATIONAHA.110.973784","article-title":"Cardiovascular effects of 1year of progressive and vigorous exercise training in previously sedentary individuals older than 65years of age","volume":"122","author":"Fujimoto","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.autneu.2016.11.002_bb0125","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1161\/HYPERTENSIONAHA.111.00797","article-title":"Central mineralocorticoid receptors and the role of angiotensin II and glutamate in the paraventricular nucleus of rats with angiotensin II-induced hypertension","volume":"61","author":"Gabor","year":"2013","journal-title":"Hypertension"},{"key":"10.1016\/j.autneu.2016.11.002_bb0130","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1161\/HYPERTENSIONAHA.116.07681","article-title":"Autonomic blockade reverses endothelial dysfunction in obesity-associated hypertension","volume":"68","author":"Gamboa","year":"2016","journal-title":"Hypertension"},{"key":"10.1016\/j.autneu.2016.11.002_bb0135","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s10286-005-0224-4","article-title":"Reproducibility of methods for assessing baroreflex sensitivity and temporal QT variability in end-stage renal disease and healthy subjects","volume":"15","author":"Gao","year":"2005","journal-title":"Clin. Auton. Res."},{"key":"10.1016\/j.autneu.2016.11.002_bb0140","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1056\/NEJMoa041031","article-title":"Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization","volume":"351","author":"Go","year":"2004","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.autneu.2016.11.002_bb0145","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1038\/hr.2015.100","article-title":"Effect of exercise training on the renin-angiotensin-aldosterone system in healthy individuals: a systematic review and meta-analysis","volume":"39","author":"Goessler","year":"2016","journal-title":"Hypertens. Res."},{"key":"10.1016\/j.autneu.2016.11.002_bb0150","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1161\/01.CIR.81.5.1606","article-title":"Positron emission tomographic imaging of cardiac sympathetic innervation and function","volume":"81","author":"Goldstein","year":"1990","journal-title":"Circulation"},{"key":"10.1016\/j.autneu.2016.11.002_bb0155","doi-asserted-by":"crossref","first-page":"192","DOI":"10.3389\/fphys.2015.00192","article-title":"Neural regulation of the kidney function in rats with cisplatin induced renal failure","volume":"6","author":"Goulding","year":"2015","journal-title":"Front. Physiol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0160","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1161\/01.HYP.23.3.294","article-title":"Physical training and baroreceptor control of sympathetic nerve activity in humans","volume":"23","author":"Grassi","year":"1994","journal-title":"Hypertension"},{"key":"10.1016\/j.autneu.2016.11.002_bb0165","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1161\/01.HYP.0000058003.27729.5A","article-title":"Short-versus long-term effects of different dihydropyridines on sympathetic and baroreflex function in hypertension","volume":"41","author":"Grassi","year":"2003","journal-title":"Hypertension"},{"key":"10.1016\/j.autneu.2016.11.002_bb0170","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1161\/HYPERTENSIONAHA.110.164780","article-title":"Early sympathetic activation in the initial clinical stages of chronic renal failure","volume":"57","author":"Grassi","year":"2011","journal-title":"Hypertension"},{"key":"10.1016\/j.autneu.2016.11.002_bb0175","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1161\/HYPERTENSIONAHA.114.04823","article-title":"Blood pressure responses to renal denervation precede and are independent of the sympathetic and baroreflex effects","volume":"65","author":"Grassi","year":"2015","journal-title":"Hypertension"},{"key":"10.1016\/j.autneu.2016.11.002_bb0180","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1113\/expphysiol.2009.048694","article-title":"Exercise and vascular adaptation in asymptomatic humans","volume":"96","author":"Green","year":"2011","journal-title":"Exp. Physiol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0185","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1053\/j.ajkd.2014.07.015","article-title":"Effect of exercise training on estimated GFR, vascular health, and cardiorespiratory fitness in patients with CKD: a pilot randomized controlled trial","volume":"65","author":"Greenwood","year":"2015","journal-title":"Am. J. Kidney Dis."},{"key":"10.1016\/j.autneu.2016.11.002_bb0190","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.autneu.2014.10.015","article-title":"Central mechanisms for exercise training-induced reduction in sympatho-excitation in chronic heart failure","volume":"188","author":"Haack","year":"2015","journal-title":"Auton. Neurosci."},{"key":"10.1016\/j.autneu.2016.11.002_bb0195","doi-asserted-by":"crossref","first-page":"193","DOI":"10.2165\/00007256-200030030-00004","article-title":"The role of exercise training in the treatment of hypertension: an update","volume":"30","author":"Hagberg","year":"2000","journal-title":"Sports Med."},{"key":"10.1016\/j.autneu.2016.11.002_bb0200","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1161\/01.CIR.73.4.615","article-title":"Norepinephrine spillover to plasma in patients with congestive heart failure: evidence of increased overall and cardiorenal sympathetic nervous activity","volume":"73","author":"Hasking","year":"1986","journal-title":"Circulation"},{"key":"10.1016\/j.autneu.2016.11.002_bb0205","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.1161\/01.CIR.0000034043.16664.96","article-title":"Sympathetic nerve activity in end-stage renal disease","volume":"106","author":"Hausberg","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.autneu.2016.11.002_bb0210","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD003236.pub2","article-title":"Exercise training for adults with chronic kidney disease","author":"Heiwe","year":"2011","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.autneu.2016.11.002_bb0215","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1161\/HYPERTENSIONAHA.111.00194","article-title":"Substantial reduction in single sympathetic nerve firing after renal denervation in patients with resistant hypertension","volume":"61","author":"Hering","year":"2013","journal-title":"Hypertension"},{"key":"10.1016\/j.autneu.2016.11.002_bb0220","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1161\/HYPERTENSIONAHA.113.03098","article-title":"Sustained sympathetic and blood pressure reduction 1year after renal denervation in patients with resistant hypertension","volume":"64","author":"Hering","year":"2014","journal-title":"Hypertension"},{"key":"10.1016\/j.autneu.2016.11.002_bb0225","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1677\/joe.0.1160443","article-title":"Effects of physical endurance training on the plasma renin-angiotensin-aldosterone system in normal man","volume":"116","author":"Hespel","year":"1988","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0230","doi-asserted-by":"crossref","first-page":"473","DOI":"10.2165\/11630800-000000000-00000","article-title":"Exercise training in chronic kidney disease patients","volume":"42","author":"Howden","year":"2012","journal-title":"Sports Med."},{"key":"10.1016\/j.autneu.2016.11.002_bb0235","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.2215\/CJN.10141012","article-title":"Effects of exercise and lifestyle intervention on cardiovascular function in CKD","volume":"8","author":"Howden","year":"2013","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0240","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1097\/MNH.0000000000000165","article-title":"The role of exercise training in the management of chronic kidney disease","volume":"24","author":"Howden","year":"2015","journal-title":"Curr. Opin. Nephrol. Hypertens."},{"key":"10.1016\/j.autneu.2016.11.002_bb0245","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1053\/j.ajkd.2014.09.017","article-title":"Exercise training in CKD: efficacy, adherence, and safety","volume":"65","author":"Howden","year":"2015","journal-title":"Am. J. Kidney Dis."},{"key":"10.1016\/j.autneu.2016.11.002_bb0250","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1161\/HYPERTENSIONAHA.112.193607","article-title":"Renal responses to chronic suppression of central sympathetic outflow","volume":"60","author":"Iliescu","year":"2012","journal-title":"Hypertension"},{"key":"10.1016\/j.autneu.2016.11.002_bb0255","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1152\/japplphysiol.00482.2003","article-title":"Dose-response relationship of the cardiovascular adaptation to endurance training in healthy adults: how much training for what benefit?","volume":"95","author":"Iwasaki","year":"2003","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0260","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1161\/01.CIR.73.1.30","article-title":"The effects of changes in physical activity on major cardiovascular risk factors, hemodynamics, sympathetic function, and glucose utilization in man: a controlled study of four levels of activity","volume":"73","author":"Jennings","year":"1986","journal-title":"Circulation"},{"key":"10.1016\/j.autneu.2016.11.002_bb0265","article-title":"Exercise training attenuates hypertension and cardiac hypertrophy by modulating neurotransmitters and cytokines in hypothalamic paraventricular nucleus","volume":"9","author":"Jia","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.autneu.2016.11.002_bb0270","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1053\/j.ajkd.2011.10.008","article-title":"Exercise in individuals with CKD","volume":"59","author":"Johansen","year":"2012","journal-title":"Am. J. Kidney Dis."},{"key":"10.1016\/j.autneu.2016.11.002_bb0275","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/j.amjhyper.2005.02.002","article-title":"Reduced baroreflex effectiveness index in hypertensive patients with chronic renal failure","volume":"18","author":"Johansson","year":"2005","journal-title":"Am. J. Hypertens."},{"key":"10.1016\/j.autneu.2016.11.002_bb0280","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1002\/j.2040-4603.2011.tb00345.x","article-title":"Neural control of renal function","volume":"1","author":"Johns","year":"2011","journal-title":"Compr. Physiol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0285","doi-asserted-by":"crossref","first-page":"5551","DOI":"10.1113\/jphysiol.2009.179432","article-title":"Exercise protects the cardiovascular system: effects beyond traditional risk factors","volume":"587","author":"Joyner","year":"2009","journal-title":"J. Physiol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0290","doi-asserted-by":"crossref","first-page":"53","DOI":"10.5527\/wjn.v5.i1.53","article-title":"Baroreflex dysfunction in chronic kidney disease","volume":"5","author":"Kaur","year":"2016","journal-title":"World J. Nephrol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0295","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1111\/jch.12724","article-title":"Long-term effects of renal sympathetic denervation on hypertensive patients with mild to moderate chronic kidney disease","volume":"18","author":"Kiuchi","year":"2016","journal-title":"J. Clin. Hypertens. (Greenwich)"},{"key":"10.1016\/j.autneu.2016.11.002_bb0300","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1016\/S0140-6736(09)60566-3","article-title":"Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study","volume":"373","author":"Krum","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.autneu.2016.11.002_bb0305","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1161\/HYPERTENSIONAHA.106.085548","article-title":"Exercise training restores baroreflex sensitivity in never-treated hypertensive patients","volume":"49","author":"Laterza","year":"2007","journal-title":"Hypertension"},{"key":"10.1016\/j.autneu.2016.11.002_bb0310","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1161\/01.CIR.84.3.1016","article-title":"Left ventricular pressure-volume and Frank-Starling relations in endurance athletes. Implications for orthostatic tolerance and exercise performance","volume":"84","author":"Levine","year":"1991","journal-title":"Circulation"},{"key":"10.1016\/j.autneu.2016.11.002_bb0315","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1161\/01.HYP.0000259666.99449.74","article-title":"Glutamatergic inputs in the hypothalamic paraventricular nucleus maintain sympathetic vasomotor tone in hypertension","volume":"49","author":"Li","year":"2007","journal-title":"Hypertension"},{"key":"10.1016\/j.autneu.2016.11.002_bb0320","doi-asserted-by":"crossref","first-page":"H2847","DOI":"10.1152\/ajpheart.00625.2005","article-title":"Interaction between glutamate and GABA systems in the integration of sympathetic outflow by the paraventricular nucleus of the hypothalamus","volume":"291","author":"Li","year":"2006","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0325","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1161\/01.CIR.102.15.1854","article-title":"Chronic exercise reduces sympathetic nerve activity in rabbits with pacing-induced heart failure: a role for angiotensin II","volume":"102","author":"Liu","year":"2000","journal-title":"Circulation"},{"issue":"1985","key":"10.1016\/j.autneu.2016.11.002_bb0330","doi-asserted-by":"crossref","first-page":"2403","DOI":"10.1152\/japplphysiol.00039.2002","article-title":"Exercise training enhances baroreflex control of heart rate by a vagal mechanism in rabbits with heart failure","volume":"92","author":"Liu","year":"2002","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0335","first-page":"148","article-title":"The baroreflex as a long-term controller of arterial pressure","volume":"30","author":"Lohmeier","year":"2015","journal-title":"Physiology (Bethesda)"},{"key":"10.1016\/j.autneu.2016.11.002_bb0340","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.1523\/JNEUROSCI.3455-15.2016","article-title":"Acute modulation of cortical glutamate and GABA content by physical activity","volume":"36","author":"Maddock","year":"2016","journal-title":"J. Neurosci."},{"key":"10.1016\/j.autneu.2016.11.002_bb0345","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1161\/01.HYP.18.5.575","article-title":"Exercise training lowers resting renal but not cardiac sympathetic activity in humans","volume":"18","author":"Meredith","year":"1991","journal-title":"Hypertension"},{"key":"10.1016\/j.autneu.2016.11.002_bb0350","first-page":"1108","article-title":"The effect of residential exercise training on baroreflex control of heart rate and sympathetic nerve activity in patients with acute myocardial infarction","volume":"127","author":"Mimura","year":"2005","journal-title":"Chest"},{"issue":"1985","key":"10.1016\/j.autneu.2016.11.002_bb0355","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1152\/japplphysiol.00601.2007","article-title":"Exercise training enhances baroreflex sensitivity by an angiotensin II-dependent mechanism in chronic heart failure","volume":"104","author":"Mousa","year":"2008","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0360","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1111\/j.1440-1681.2007.04590.x","article-title":"Exercise training and sympathetic nervous system activity: evidence for physical activity dependent neural plasticity","volume":"34","author":"Mueller","year":"2007","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0365","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1007\/s11255-010-9823-7","article-title":"Effects of exercise training on physical impairment, arterial stiffness and health-related quality of life in patients with chronic kidney disease: a pilot study","volume":"43","author":"Mustata","year":"2011","journal-title":"Int. Urol. Nephrol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0370","first-page":"R365","article-title":"Effect of exercise training on RSNA, baroreflex control, and blood pressure responsiveness","volume":"265","author":"Negrao","year":"1993","journal-title":"Am. J. Phys."},{"key":"10.1016\/j.autneu.2016.11.002_bb0375","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1111\/j.1523-1755.2004.00465.x","article-title":"Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease","volume":"65","author":"Oberg","year":"2004","journal-title":"Kidney Int."},{"issue":"1985","key":"10.1016\/j.autneu.2016.11.002_bb0380","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1152\/jappl.1999.86.5.1583","article-title":"Sympathetic adaptations to one-legged training","volume":"86","author":"Ray","year":"1999","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0385","doi-asserted-by":"crossref","first-page":"H229","DOI":"10.1152\/ajpheart.00880.2009","article-title":"Effects of aerobic exercise training on sympathetic and renal responses to mental stress in humans","volume":"298","author":"Ray","year":"2010","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0390","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1016\/S0735-1097(03)00831-3","article-title":"The effects of exercise training on sympathetic neural activation in advanced heart failure: a randomized controlled trial","volume":"42","author":"Roveda","year":"2003","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0395","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1097\/00004872-199917080-00012","article-title":"Neural mechanisms in human obesity-related hypertension","volume":"17","author":"Rumantir","year":"1999","journal-title":"J. Hypertens."},{"key":"10.1016\/j.autneu.2016.11.002_bb0400","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1161\/01.HYP.0000103160.35395.9E","article-title":"Sympathetic augmentation in hypertension: role of nerve firing, norepinephrine reuptake, and Angiotensin neuromodulation","volume":"43","author":"Schlaich","year":"2004","journal-title":"Hypertension"},{"key":"10.1016\/j.autneu.2016.11.002_bb0405","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1056\/NEJMc0904179","article-title":"Renal sympathetic-nerve ablation for uncontrolled hypertension","volume":"361","author":"Schlaich","year":"2009","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.autneu.2016.11.002_bb0410","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1681\/ASN.2008040402","article-title":"Sympathetic activation in chronic renal failure","volume":"20","author":"Schlaich","year":"2009","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0415","doi-asserted-by":"crossref","first-page":"2214","DOI":"10.1016\/j.ijcard.2013.01.218","article-title":"Feasibility of catheter-based renal nerve ablation and effects on sympathetic nerve activity and blood pressure in patients with end-stage renal disease","volume":"168","author":"Schlaich","year":"2013","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0420","doi-asserted-by":"crossref","DOI":"10.1681\/ASN.2015091034","article-title":"Neither hematocrit normalization nor exercise training restores oxygen consumption to normal levels in hemodialysis patients","author":"Stray-Gundersen","year":"2016","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0425","doi-asserted-by":"crossref","first-page":"71","DOI":"10.2337\/db09-0934","article-title":"Sympathetic neural adaptation to hypocaloric diet with or without exercise training in obese metabolic syndrome subjects","volume":"59","author":"Straznicky","year":"2010","journal-title":"Diabetes"},{"key":"10.1016\/j.autneu.2016.11.002_bb0430","doi-asserted-by":"crossref","first-page":"E503","DOI":"10.1210\/jc.2010-2204","article-title":"The effects of weight loss versus weight loss maintenance on sympathetic nervous system activity and metabolic syndrome components","volume":"96","author":"Straznicky","year":"2011","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.autneu.2016.11.002_bb0435","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1097\/HJH.0b013e3283418875","article-title":"Exercise augments weight loss induced improvement in renal function in obese metabolic syndrome individuals","volume":"29","author":"Straznicky","year":"2011","journal-title":"J. Hypertens."},{"key":"10.1016\/j.autneu.2016.11.002_bb0440","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1111\/j.1748-1716.1984.tb07413.x","article-title":"Skeletal muscle sympathetic activity at rest in trained and untrained subjects","volume":"120","author":"Svedenhag","year":"1984","journal-title":"Acta Physiol. Scand."},{"key":"10.1016\/j.autneu.2016.11.002_bb0445","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1161\/hy1201.096120","article-title":"Limited effect of systemic beta-blockade on sympathetic outflow","volume":"38","author":"Tank","year":"2001","journal-title":"Hypertension"},{"key":"10.1016\/j.autneu.2016.11.002_bb0450","first-page":"1775","article-title":"Cardiac and extracardiac sympathetic denervation in Parkinson's disease with orthostatic hypotension and in pure autonomic failure","volume":"46","author":"Tipre","year":"2005","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.autneu.2016.11.002_bb0455","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1042\/cs0580021","article-title":"Baroreflex sensitivity in renal failure","volume":"58","author":"Tomiyama","year":"1980","journal-title":"Clin. Sci. (Lond.)"},{"key":"10.1016\/j.autneu.2016.11.002_bb0460","doi-asserted-by":"crossref","first-page":"H974","DOI":"10.1152\/ajpheart.01090.2002","article-title":"Weight loss improves neurovascular and muscle metaboreflex control in obesity","volume":"285","author":"Trombetta","year":"2003","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0465","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/0140-6736(92)90865-Z","article-title":"Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure","volume":"339","author":"Vallance","year":"1992","journal-title":"Lancet"},{"key":"10.1016\/j.autneu.2016.11.002_bb0470","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1152\/physrev.1979.59.4.919","article-title":"Somatosensory, proprioceptive, and sympathetic activity in human peripheral nerves","volume":"59","author":"Vallbo","year":"1979","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.autneu.2016.11.002_bb0475","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1113\/jphysiol.1992.sp019217","article-title":"Simultaneous measurements of cardiac noradrenaline spillover and sympathetic outflow to skeletal muscle in humans","volume":"453","author":"Wallin","year":"1992","journal-title":"J. Physiol."},{"issue":"Pt 3","key":"10.1016\/j.autneu.2016.11.002_bb0480","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1113\/jphysiol.1996.sp021265","article-title":"Renal noradrenaline spillover correlates with muscle sympathetic activity in humans","volume":"491","author":"Wallin","year":"1996","journal-title":"J. Physiol."},{"key":"10.1016\/j.autneu.2016.11.002_bb0485","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1136\/bjsports-2013-092576","article-title":"High-intensity interval training in patients with lifestyle-induced cardiometabolic disease: a systematic review and meta-analysis","volume":"48","author":"Weston","year":"2014","journal-title":"Br. J. Sports Med."},{"key":"10.1016\/j.autneu.2016.11.002_bb2000","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1038\/ki.1997.103","article-title":"Renal afferent impulses, the posterior hypothalamus, and hypertension in rats with chronic renal failure","volume":"51","author":"Ye","year":"1997","journal-title":"Kidney Int."},{"key":"10.1016\/j.autneu.2016.11.002_bb0490","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1161\/hc1102.105261","article-title":"Plasma norepinephrine predicts survival and incident cardiovascular events in patients with end-stage renal disease","volume":"105","author":"Zoccali","year":"2002","journal-title":"Circulation"}],"container-title":["Autonomic Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1566070216302636?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1566070216302636?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T12:09:01Z","timestamp":1761566941000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1566070216302636"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5]]},"references-count":99,"alternative-id":["S1566070216302636"],"URL":"https:\/\/doi.org\/10.1016\/j.autneu.2016.11.002","relation":{},"ISSN":["1566-0702"],"issn-type":[{"value":"1566-0702","type":"print"}],"subject":[],"published":{"date-parts":[[2017,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Potential role of endurance training in altering renal sympathetic nerve activity in CKD?","name":"articletitle","label":"Article Title"},{"value":"Autonomic Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.autneu.2016.11.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}