{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:08:18Z","timestamp":1787314098304,"version":"build-2736575974"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["PQ304388\/2017-3"],"award-info":[{"award-number":["PQ304388\/2017-3"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["CBB-APQ-01463-15"],"award-info":[{"award-number":["CBB-APQ-01463-15"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["33\/2014"],"award-info":[{"award-number":["33\/2014"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004901","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","doi-asserted-by":"publisher","award":["RED-00282-16"],"award-info":[{"award-number":["RED-00282-16"]}],"id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004901","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","doi-asserted-by":"publisher","award":["APQ-01510-17"],"award-info":[{"award-number":["APQ-01510-17"]}],"id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004901","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","doi-asserted-by":"publisher","award":["APQ-01553-15"],"award-info":[{"award-number":["APQ-01553-15"]}],"id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["autonomicneuroscience.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Autonomic Neuroscience"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1016\/j.autneu.2020.102695","type":"journal-article","created":{"date-parts":[[2020,6,24]],"date-time":"2020-06-24T11:43:38Z","timestamp":1592999018000},"page":"102695","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"special_numbering":"C","title":["Autonomic and cardiovascular consequences resulting from experimental hemorrhagic stroke in the left or right intermediate insular cortex in rats"],"prefix":"10.1016","volume":"227","author":[{"given":"Fernanda Ribeiro","family":"Marins","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo","family":"Limbor\u00e7o-Filho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e1rbara Flecha","family":"D'Abreu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro W.","family":"Machado de Almeida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana","family":"Gavioli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Henrique","family":"Xavier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen M.","family":"Oppenheimer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Guatimosim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco Ant\u00f4nio Peliky","family":"Fontes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.autneu.2020.102695_bb0005","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1002\/ana.20806","article-title":"Insular involvement in brain infarction increases risk for cardiac arrhythmia and death","volume":"59","author":"Abboud","year":"2006","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.autneu.2020.102695_bb0010","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1161\/HYPERTENSIONAHA.111.199539","article-title":"Functional cross-talk between aldosterone and angiotensin-(1\u20137) in ventricular myocytes","volume":"61","author":"de Almeida","year":"2013","journal-title":"Hypertension"},{"key":"10.1016\/j.autneu.2020.102695_bb0015","series-title":"Sports Cardiology","first-page":"179","article-title":"Pre-excitation syndrome","author":"Bisceglia","year":"2012"},{"key":"10.1016\/j.autneu.2020.102695_bb0020","doi-asserted-by":"crossref","first-page":"2094","DOI":"10.1161\/01.STR.0000138452.81003.4c","article-title":"Cardiac autonomic derangement and arrhythmias in right-sided stroke with insular involvement","volume":"35","author":"Colivicchi","year":"2004","journal-title":"Stroke"},{"key":"10.1016\/j.autneu.2020.102695_bb0025","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.autneu.2017.01.001","article-title":"Asymmetric sympathetic output: the dorsomedial hypothalamus as a potential link between emotional stress and cardiac arrhythmias","volume":"207","author":"Fontes","year":"2017","journal-title":"Auton. Neurosci."},{"key":"10.1016\/j.autneu.2020.102695_bb0030","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/S0165-6147(03)00192-5","article-title":"Animal models of stroke: do they have value for discovering neuroprotective agents?","volume":"24","author":"Green","year":"2003","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.autneu.2020.102695_bb0035","first-page":"C1327","article-title":"Molecular identification of a TTX-sensitive Ca2+ current","volume":"280","author":"Guatimosim","year":"2001","journal-title":"Am. J. Phys. Cell Phys."},{"key":"10.1016\/j.autneu.2020.102695_bb0040","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1161\/01.RES.75.3.434","article-title":"Relation between myocardial function and expression of sarcoplasmic reticulum Ca2+-ATPase in failing and nonfailing human myocardium","volume":"75","author":"Hasenfuss","year":"1994","journal-title":"Circ. Res."},{"key":"10.1016\/j.autneu.2020.102695_bb0045","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1161\/01.STR.0000247868.97078.10","article-title":"Brain injury after intracerebral hemorrhage: the role of thrombin and iron","volume":"38","author":"Hua","year":"2007","journal-title":"Stroke"},{"key":"10.1016\/j.autneu.2020.102695_bb0050","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1212\/01.wnl.0000202684.29640.60","article-title":"Left insular stroke is associated with adverse cardiac outcome","volume":"66","author":"Laowattana","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.autneu.2020.102695_bb0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1146\/annurev.physiol.010908.163156","article-title":"Sex-based cardiac physiology","volume":"71","author":"Luczak","year":"2009","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.autneu.2020.102695_bb0060","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1111\/1440-1681.12542","article-title":"Functional topography of cardiovascular regulation along the rostrocaudal axis of the rat posterior insular cortex","volume":"43","author":"Marins","year":"2016","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.autneu.2020.102695_bb0065","doi-asserted-by":"crossref","first-page":"e58","DOI":"10.1111\/ene.13605","article-title":"Atrial fibrillation after acute intracerebral hemorrhage: how would the insular cortex damage interact?","volume":"25","author":"Nagai","year":"2018","journal-title":"Eur. J. Neurol."},{"key":"10.1016\/j.autneu.2020.102695_bb0070","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1161\/STROKEAHA.107.486654","article-title":"Edaravone attenuates brain edema and neurologic deficits in a rat model of acute intracerebral hemorrhage","volume":"39","author":"Nakamura","year":"2008","journal-title":"Stroke"},{"key":"10.1016\/j.autneu.2020.102695_bb0075","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1002\/j.2040-4603.2016.tb00691.x","article-title":"The insular cortex and the regulation of cardiac function","volume":"6","author":"Oppenheimer","year":"2011","journal-title":"Compr. Physiol."},{"key":"10.1016\/j.autneu.2020.102695_bb0080","series-title":"The Rat Brain in Stereotaxic Coordinates","author":"Paxinos","year":"1986"},{"key":"10.1016\/j.autneu.2020.102695_bb0085","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1161\/01.CIR.0000023042.50192.F4","article-title":"Rate dependence of [Na+]i and contractility in nonfailing and failing human myocardium","volume":"106","author":"Pieske","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.autneu.2020.102695_bb0090","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1097\/01.CCM.0000063047.63862.99","article-title":"Extracellular glutamate and other amino acids in experimental intracerebral hemorrhage: an in vivo microdialysis study","volume":"31","author":"Qureshi","year":"2003","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.autneu.2020.102695_bb0095","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.brainres.2012.02.021","article-title":"Cardiovascular responses evoked by activation or blockade of GABAA receptors in the hypothalamic PVN are attenuated in transgenic rats with low brain angiotensinogen","volume":"1448","author":"da Silva","year":"2012","journal-title":"Brain Res."},{"key":"10.1016\/j.autneu.2020.102695_bb0100","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1002\/jcp.10024","article-title":"Adrenergic regulation of cardiac myocyte apoptosis","volume":"189","author":"Singh","year":"2001","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.autneu.2020.102695_bb0105","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1161\/01.STR.25.5.1053","article-title":"Cardiac arrhythmia associated with reversible damage to insula in a patients with subarachnoid hemorrhage","volume":"25","author":"Svigelj","year":"1994","journal-title":"Stroke"},{"key":"10.1016\/j.autneu.2020.102695_bb0110","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1136\/jnnp.2007.121319","article-title":"Repetitive asystole in right insular hemorrhage","author":"Sykora","year":"2007","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.autneu.2020.102695_bb0115","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1161\/01.STR.0000255033.02904.db","article-title":"Modeling intracerebal hemorrhage: glutamate, nuclear factor-\u03baB signaling and cytokines","volume":"38","author":"Wagner","year":"2007","journal-title":"Stroke"},{"key":"10.1016\/j.autneu.2020.102695_bb0120","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1007\/s00424-013-1260-x","article-title":"Stroke: understanding the differences between males and females","volume":"465","author":"Wilson","year":"2013","journal-title":"Pfl\u00fcgers Arch.-Eur. J. Physiol."},{"key":"10.1016\/j.autneu.2020.102695_bb0125","first-page":"R664","article-title":"Asymmetry in the control of cardiac performance by dorsomedial hypothalamus","volume":"304","author":"Xavier","year":"2013","journal-title":"Am. J. Phys. Regul. Integr. Comp. Phys."},{"key":"10.1016\/j.autneu.2020.102695_bb0130","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1161\/STROKEAHA.108.520882","article-title":"Chronic kidney disease and clinical outcome in patients with acute stroke","volume":"40","author":"Yahalom","year":"2009","journal-title":"Stroke"}],"container-title":["Autonomic Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1566070220301296?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1566070220301296?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T20:40:37Z","timestamp":1778618437000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1566070220301296"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":26,"alternative-id":["S1566070220301296"],"URL":"https:\/\/doi.org\/10.1016\/j.autneu.2020.102695","relation":{},"ISSN":["1566-0702"],"issn-type":[{"value":"1566-0702","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Autonomic and cardiovascular consequences resulting from experimental hemorrhagic stroke in the left or right intermediate insular cortex in rats","name":"articletitle","label":"Article Title"},{"value":"Autonomic Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.autneu.2020.102695","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"102695"}}