{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T00:57:00Z","timestamp":1790902620637,"version":"4.1.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T00:00:00Z","timestamp":1277942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Autoimmunity Reviews"],"published-print":{"date-parts":[[2010,7]]},"DOI":"10.1016\/j.autrev.2010.05.008","type":"journal-article","created":{"date-parts":[[2010,5,11]],"date-time":"2010-05-11T11:53:02Z","timestamp":1273578782000},"page":"615-617","source":"Crossref","is-referenced-by-count":26,"title":["Functional role of M3 muscarinic acetylcholine receptor (M3R) reactive T cells and anti-M3R autoantibodies in patients with Sj\u00f6gren's syndrome"],"prefix":"10.1016","volume":"9","author":[{"given":"Takayuki","family":"Sumida","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroto","family":"Tsuboi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mana","family":"Iizuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumi","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isao","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.autrev.2010.05.008_bib1","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1172\/JCI115635","article-title":"T cell receptor repertoire of infiltrating T cells in lips of Sj\u00f6gren's syndrome patients","volume":"89","author":"Sumida","year":"1992","journal-title":"J Clin Invest"},{"key":"10.1016\/j.autrev.2010.05.008_bib2","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1002\/art.1780351118","article-title":"Restricted junctional usage of T cell receptor V\u03b22 and V\u03b213 genes, which are overrepresented on infliltrating T cells in the lips of patients with Sj\u00f6gren's syndrome","volume":"35","author":"Yonaha","year":"1992","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.autrev.2010.05.008_bib3","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1172\/JCI116593","article-title":"Characterization of the primary structure of T cell receptor \u03b2 chains in cells infiltrating the salivary gland in the sicca syndrome of HIC-1 infection","volume":"92","author":"Dwyer","year":"1993","journal-title":"J Clin Invest"},{"key":"10.1016\/j.autrev.2010.05.008_bib4","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1002\/eji.1830240128","article-title":"Infiltrating T cells from patients with primary Sjogern's syndrome express restricted or unrestricted T cell receptor V\u03b2regions depending on the stage of the disease","volume":"24","author":"Legras","year":"1994","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.autrev.2010.05.008_bib5","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1093\/rheumatology\/33.5.420","article-title":"Nawata, et al. LA-DR alleles in patients with Sjogren's syndrome over-representing V\u03b22 and V\u03b213 genes in the labial salivary glnads","volume":"33","author":"Sumida","year":"1994","journal-title":"Br J Rheumatol"},{"key":"10.1016\/j.autrev.2010.05.008_bib6","first-page":"1655","article-title":"T cell receptor V\u03b1 repertoire of infiltrating T cells in labial salivary glands from patients with Sjogren's syndrome","volume":"21","author":"Sumida","year":"1994","journal-title":"J Rheumatol"},{"key":"10.1016\/j.autrev.2010.05.008_bib7","first-page":"1832","article-title":"Selective expansion of V\u03b2 families by T cells in the blood and salivary gland infiltrate of patients with primary Sj\u00f6gren's syndrome","volume":"21","author":"Smith","year":"1994","journal-title":"J Rheumatol"},{"key":"10.1016\/j.autrev.2010.05.008_bib8","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.4049\/jimmunol.158.2.1020","article-title":"TCR in Fas-sensitive T ells from labial salivary glands of patients with Sjogren's syndrome","volume":"158","author":"Sumida","year":"1997","journal-title":"J Immunol"},{"key":"10.1016\/j.autrev.2010.05.008_bib9","first-page":"519","article-title":"Single cell analysis of T cells infiltrating labial salivary glands from patients with Sjogren's syndrome","volume":"4","author":"Matsumoto","year":"1999","journal-title":"Int J Mol Med"},{"key":"10.1016\/j.autrev.2010.05.008_bib10","first-page":"S403","article-title":"Molecular evidence of antigen-driven V\u03b213.2T cells in the lip biopsies and peripheral blood of anti-52kDa Ro autoantibody positive Sjogren's syndrome patients","author":"Furrie","year":"1999","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.autrev.2010.05.008_bib11","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/j.1365-2249.1995.tb02273.x","article-title":"Diverse T cell receptor \u03b2 gene usage by infiltrating T cells in the lacrimal glands of Sjogren's syndrome","volume":"101","author":"Mizushima","year":"1995","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.autrev.2010.05.008_bib12","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1172\/JCI118629","article-title":"Common T cell receptor clonotype in lacrimal glands and labial salivary glands from patients with Sjogren's syndrome","volume":"97","author":"Matsumoto","year":"1996","journal-title":"J Clin Invest"},{"key":"10.1016\/j.autrev.2010.05.008_bib13","doi-asserted-by":"crossref","first-page":"4084","DOI":"10.4049\/jimmunol.155.8.4084","article-title":"Limited T cell receptor repertoire of infiltrating T cells in the kidneys of Sj\u00f6gren's syndrome patients with interstitial nephritis","volume":"155","author":"Murata","year":"1995","journal-title":"J Immunol"},{"key":"10.1016\/j.autrev.2010.05.008_bib14","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1111\/j.1365-2249.1991.tb05715.x","article-title":"An abnormal T cell repertoire in hypergammaglobulinemic primary Sjogren's syndrome","volume":"85","author":"Kay","year":"1991","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.autrev.2010.05.008_bib15","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/0198-8859(94)00115-7","article-title":"A subset of Sj\u00f6gren's syndrome associates with the TCRBV13S2 locus but not the TCRBV2S1 locus","volume":"42","author":"Kay","year":"1995","journal-title":"Hum Immunol"},{"key":"10.1016\/j.autrev.2010.05.008_bib16","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1016\/S0140-6736(05)65741-8","article-title":"New T cell epitope of Ro\/SS-A 52kDa protein in labial salivary glands from patients with Sjogren's syndrome","volume":"348","author":"Sumida","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.autrev.2010.05.008_bib17","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.1002\/art.1780401225","article-title":"Regulatory T cell epitope recognized by T cells from labial salivary glnads of patients with Sj\u00f6gren's syndrome","volume":"40","author":"Sumida","year":"1997","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.autrev.2010.05.008_bib18","first-page":"485","article-title":"\u03b1-amylase functions as a salivary gland-specific self T cell epitope in patients with Sjogren's syndrome","volume":"3","author":"Matumoto","year":"1999","journal-title":"Int J Mol Med"},{"key":"10.1016\/j.autrev.2010.05.008_bib19","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1136\/ard.2005.039065","article-title":"Altered peptide ligands regulate muscarinic acetylcholine receptor reactive T cells of patients with Sjogren's syndrome","volume":"65","author":"Naito","year":"2005","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.autrev.2010.05.008_bib20","doi-asserted-by":"crossref","first-page":"7538","DOI":"10.1073\/pnas.95.13.7538","article-title":"Transfer of human serum IgG to nonobese diabetic Ig\u03bcnull mice reveals a role for autoantibodies in the loss of secretory function of exocrime tissues in Sjogren's syndrome","volume":"95","author":"Robinson","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.autrev.2010.05.008_bib21","first-page":"321","article-title":"Muscarinic acetylcholine receptor antibodies as a new marker of dry eye Sj\u00f6gren's syndrome","volume":"42","author":"Bacman","year":"2001","journal-title":"Invest Opthalmol Cis Sc"},{"key":"10.1016\/j.autrev.2010.05.008_bib22","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.1002\/1529-0131(200010)43:10<2297::AID-ANR18>3.0.CO;2-X","article-title":"Evidence for anti-muscarinic acetylcholine receptor antibody-mediated secretory dysfunction in NOD mice","volume":"43","author":"Nguyen","year":"2000","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.autrev.2010.05.008_bib23","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1136\/ard.2004.025478","article-title":"Muscarinic acetylcholine receptor autoantibodies in patients with Sj\u00f6gren's syndrome","volume":"64","author":"Naito","year":"2005","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.autrev.2010.05.008_bib24","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1136\/ard.2007.072421","article-title":"High prevalence of autoantibodies to muscarinic-3 acetylcholine receptor in patients with juvenile-onset Sj\u00f6gren's syndrome","volume":"67","author":"Nakamura","year":"2008","journal-title":"Ann Rheum Dis"}],"container-title":["Autoimmunity Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568997210000844?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568997210000844?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T03:46:49Z","timestamp":1685591209000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1568997210000844"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7]]},"references-count":24,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2010,7]]}},"alternative-id":["S1568997210000844"],"URL":"https:\/\/doi.org\/10.1016\/j.autrev.2010.05.008","relation":{},"ISSN":["1568-9972"],"issn-type":[{"value":"1568-9972","type":"print"}],"subject":[],"published":{"date-parts":[[2010,7]]}}}