{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T19:19:12Z","timestamp":1793215152648,"version":"4.5.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Autoimmunity Reviews"],"published-print":{"date-parts":[[2010,10]]},"DOI":"10.1016\/j.autrev.2010.07.016","type":"journal-article","created":{"date-parts":[[2010,8,3]],"date-time":"2010-08-03T06:43:04Z","timestamp":1280817784000},"page":"830-834","source":"Crossref","is-referenced-by-count":484,"title":["From endothelial dysfunction to atherosclerosis"],"prefix":"10.1016","volume":"9","author":[{"given":"S.","family":"Sitia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Tomasoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Atzeni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Ambrosio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Cordiano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Catapano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Tramontana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Perticone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Naccarato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Camici","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Picano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Cortigiani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Bevilacqua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Milazzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Cusi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Barlassina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Sarzi-Puttini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Turiel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.autrev.2010.07.016_bb0005","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cardiores.2004.04.028","article-title":"The multi-faceted behavior of nitric oxide in vascular \u201cinflammation\u201d: catchy terminology or true phenomenon?","volume":"63","author":"Tritto","year":"2004","journal-title":"Cardiovasc Res"},{"issue":"10","key":"10.1016\/j.autrev.2010.07.016_bb0010","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/j.autrev.2010.05.018","article-title":"Endothelial dysfunction and vascular stiffness in systemic lupus erythematosus: are they early markers of subclinical atherosclerosis?","volume":"9","author":"Zardi","year":"2010","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.autrev.2010.07.016_bb0015","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.autrev.2009.01.018","article-title":"Autonomic dysfunction in autoimmune rheumatic disease","volume":"8","author":"Stojanovich","year":"2009","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.autrev.2010.07.016_bb0020","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1007\/s12016-008-8094-x","article-title":"Atherosclerosis in autoimmune rheumatic diseases \u2014 mechanisms and clinical findings","volume":"37","author":"Zinger","year":"2009","journal-title":"Clin Rev Allerg Immunol"},{"key":"10.1016\/j.autrev.2010.07.016_bb0025","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1093\/rheumatology\/ken395","article-title":"Common inflammatory mediators orchestrate pathophysiological processes in rheumatoid arthritis and atherosclerosis","volume":"48","author":"Montecucco","year":"2009","journal-title":"Rheumatology"},{"key":"10.1016\/j.autrev.2010.07.016_bb0030","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1038\/nri1882","article-title":"The immune response in atherosclerosis: a double-edged sword","volume":"6","author":"Hansson","year":"2006","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.autrev.2010.07.016_bb0035","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.jaut.2007.02.004","article-title":"The pathogenesis of atherosclerosis in autoimmune rheumatic diseases: roles of inflammation and dyslipidemia","volume":"28","author":"Hahn","year":"2007","journal-title":"J Autoimmun"},{"key":"10.1016\/j.autrev.2010.07.016_bb0040","first-page":"1495","article-title":"Relations between autoantibodies against oxidized low-density lipoprotein, inflammation, subclinical atherosclerosis, and cardiovascular disease in rheumatoid arthritis","volume":"35","author":"Peters","year":"2008","journal-title":"J Rheumatol"},{"key":"10.1016\/j.autrev.2010.07.016_bb0045","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1007\/s10875-009-9333-5","article-title":"Autoimmunity, infectious immunity, and atherosclerosis","volume":"29","author":"Matsuura","year":"2009","journal-title":"J Clin Immunol"},{"key":"10.1016\/j.autrev.2010.07.016_bb0050","doi-asserted-by":"crossref","first-page":"17589","DOI":"10.1073\/pnas.0608757103","article-title":"Low micronutrient intake may accelerate the degenerative diseases of aging through allocation of scarce micronutrients by triage","volume":"103","author":"Ames","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.autrev.2010.07.016_bb0055","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1146\/annurev.nutr.27.061406.093705","article-title":"Epigenetic epidemiology of the developmental origins hypothesis","volume":"27","author":"Waterland","year":"2007","journal-title":"Ann Rev Nutr"},{"key":"10.1016\/j.autrev.2010.07.016_bb0060","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1161\/hy0202.103065","article-title":"Alpha-Adducin 460Trp allele is associated with erythrocyte Na transport rate in North Sardinian primary hypertensives","volume":"39","author":"Glorioso","year":"2002","journal-title":"Hypertension"},{"key":"10.1016\/j.autrev.2010.07.016_bb0065","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1161\/01.HYP.0000057010.27011.2C","article-title":"ACE and alpha-adducin polymorphism as markers of individual response to diuretic therapy","volume":"41","author":"Sciarrone","year":"2003","journal-title":"Hypertension"},{"key":"10.1016\/j.autrev.2010.07.016_bb0070","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1046\/j.1523-1755.2000.00935.x","article-title":"Synergistic effect of alpha-adducin and ACE genes causes blood pressure changes with body sodium and volume expansion","volume":"57","author":"Barlassina","year":"2000","journal-title":"Kidney Int"},{"key":"10.1016\/j.autrev.2010.07.016_bb0075","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1161\/01.HYP.0000019128.94483.3A","article-title":"ADD1 460W allele associated with cardiovascular disease in hypertensive individuals","volume":"39","author":"Morrison","year":"2002","journal-title":"Hypertension"},{"key":"10.1016\/j.autrev.2010.07.016_bb0080","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1161\/HYPERTENSIONAHA.108.112458","article-title":"Alpha-Adducin Gly460Trp variant increases the risk of stroke in hypertensive Dutch women","volume":"51","author":"Zafarmand","year":"2008","journal-title":"Hypertension"},{"key":"10.1016\/j.autrev.2010.07.016_bb0085","first-page":"297","article-title":"Apoptosis and proliferation of endothelial cells in early atherosclerotic lesions: possible role of oxidized LDL","volume":"12","author":"Norata","year":"2002","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"10.1016\/j.autrev.2010.07.016_bb0090","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1161\/01.ATV.zhq0504.1403","article-title":"HDL3 induces cyclooxygenase-2 expression and prostacyclin release in human endothelial cells via a p38 MAPK\/CRE-dependent pathway: effects on COX2\/PGI synthase coupling","volume":"24","author":"Norata","year":"2004","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.autrev.2010.07.016_bb0095","doi-asserted-by":"crossref","first-page":"119","DOI":"10.2147\/vhrm.1.2.119.64083","article-title":"Molecular mechanisms responsible for the antiinflammatory and protective effect of HDL on the endothelium","volume":"1","author":"Norata","year":"2005","journal-title":"Vasc Health Risk Manag"},{"key":"10.1016\/j.autrev.2010.07.016_bb0100","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.autrev.2008.04.018","article-title":"Oxidation of LDL and its clinical implication","volume":"7","author":"Matsuura","year":"2008","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.autrev.2010.07.016_bb0105","doi-asserted-by":"crossref","first-page":"3849","DOI":"10.1161\/01.CIR.0000150540.54220.C4","article-title":"Hypercholesterolemia stimulates angiotensin peptide synthesis and contributes to atherosclerosis through the AT1A receptor","volume":"110","author":"Daugherty","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.autrev.2010.07.016_bb0110","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1161\/01.ATV.0000022847.38083.B6","article-title":"Angiotensin II Type 1 receptor antagonism improves hypercholesterolemia-associated endothelial dysfunction","volume":"22","author":"Wassmann","year":"2002","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.autrev.2010.07.016_bb0115","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1111\/j.1475-097X.2008.00825.x","article-title":"Relationship of asymmetric dimethylarginine with flow-mediated dilatation in subjects with newly detected severe hypercholesterolemia","volume":"28","author":"Vladimirova-Kitova","year":"2008","journal-title":"Clin Physiol Funct Imaging"},{"key":"10.1016\/j.autrev.2010.07.016_bb0120","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.jacc.2005.04.040","article-title":"Asymmetric dimethylarginine, l-arginine, and endothelial dysfunction in essential hypertension","volume":"46","author":"Perticone","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.autrev.2010.07.016_bb0125","first-page":"RA91","article-title":"Asymmetric dimethylarginine (ADMA): an endogenous inhibitor of nitric oxide synthase and a novel cardiovascular risk molecule","volume":"15","author":"De Gennaro Colonna","year":"2009","journal-title":"Med Sci Monit"},{"key":"10.1016\/j.autrev.2010.07.016_bb0130","doi-asserted-by":"crossref","first-page":"F25","DOI":"10.1152\/ajprenal.00449.2003","article-title":"Upregulation of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in endothelial cells by nitric oxide deficiency","volume":"287","author":"Smirnova","year":"2004","journal-title":"Am J Physiol Ren Physiol"},{"key":"10.1016\/j.autrev.2010.07.016_bb0135","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.autrev.2009.03.001","article-title":"The therapeutic potential of targeting B cells and anti-oxLDL antibodies in atherosclerosis","volume":"9","author":"van Leeuwen","year":"2009","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.autrev.2010.07.016_bb0140","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1161\/HYPERTENSIONAHA.108.116731","article-title":"ADMA impairs nitric oxide-mediated arteriolar function due to increased superoxide production by angiotensin II\u2013NAD(P)H oxidase pathway","volume":"52","author":"Veresh","year":"2008","journal-title":"Hypertension"},{"key":"10.1016\/j.autrev.2010.07.016_bb0145","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1056\/NEJMra061889","article-title":"Coronary microvascular dysfunction","volume":"356","author":"Camici","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1016\/j.autrev.2010.07.016_bb0150","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.autrev.2009.11.002","article-title":"The heart in rheumatoid arthritis","volume":"9","author":"Turiel","year":"2010","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.autrev.2010.07.016_bb0155","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1097\/00004872-200107000-00001","article-title":"Diagnosis of myocardial ischemia in hypertensive patients","volume":"19","author":"Picano","year":"2001","journal-title":"J Hypertens"},{"key":"10.1016\/j.autrev.2010.07.016_bb0160","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1161\/01.CIR.0000153339.27064.14","article-title":"Endothelial function: cardiac events","volume":"111","author":"Lerman","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.autrev.2010.07.016_bb0165","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.autrev.2008.08.004","article-title":"Cardiovascular involvement in sistemi autoimmune diseases","volume":"8","author":"Sitia","year":"2009","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.autrev.2010.07.016_bb0170","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1016\/j.jacc.2007.06.027","article-title":"Additional prognostic value of coronary flow reserve in diabetic and nondiabetic patients with negative dipyridamole stress echocardiography by wall motion criteria","volume":"50","author":"Cortigiani","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.autrev.2010.07.016_bb0175","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1136\/hrt.2009.166439","article-title":"Prognostic correlates of combined coronary flow reserve assessment on left anterior descending and right coronary artery in patients with negative stress echocardiography by wall motion criteria","volume":"95","author":"Cortigiani","year":"2009","journal-title":"Heart"},{"key":"10.1016\/j.autrev.2010.07.016_bb0180","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1093\/eurheartj\/ehm527","article-title":"The additive prognostic value of wall motion abnormalities and coronary flow reserve during dipyridamole stress echo","volume":"29","author":"Rigo","year":"2008","journal-title":"Eur Heart J"},{"key":"10.1016\/j.autrev.2010.07.016_bb0185","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1016\/j.amjcard.2007.06.060","article-title":"Prognostic value of coronary flow reserve in medically treated patients with left anterior descending coronary disease with stenosis 51%\u201375% in diameter","volume":"100","author":"Rigo","year":"2007","journal-title":"Am J Cardiol"}],"container-title":["Autoimmunity Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568997210001540?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568997210001540?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,8]],"date-time":"2018-12-08T21:54:58Z","timestamp":1544306098000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1568997210001540"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10]]},"references-count":37,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2010,10]]}},"alternative-id":["S1568997210001540"],"URL":"https:\/\/doi.org\/10.1016\/j.autrev.2010.07.016","relation":{},"ISSN":["1568-9972"],"issn-type":[{"value":"1568-9972","type":"print"}],"subject":[],"published":{"date-parts":[[2010,10]]}}}