{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T07:17:38Z","timestamp":1790234258674,"version":"4.1.0"},"reference-count":78,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81570544"],"award-info":[{"award-number":["81570544"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Autoimmunity Reviews"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1016\/j.autrev.2017.11.012","type":"journal-article","created":{"date-parts":[[2017,11,4]],"date-time":"2017-11-04T04:33:27Z","timestamp":1509770007000},"page":"78-85","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":74,"title":["The immunobiology and clinical features of type 1 autoimmune polyglandular syndrome (APS-1)"],"prefix":"10.1016","volume":"17","author":[{"given":"Can-Jie","family":"Guo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick S.C.","family":"Leung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weici","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiong","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Eric","family":"Gershwin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.autrev.2017.11.012_bb0005","first-page":"10","article-title":"Autoimmune polyglandular syndrome","volume":"64","author":"Valsan","year":"2016","journal-title":"J Assoc Physicians India"},{"key":"10.1016\/j.autrev.2017.11.012_bb0010","doi-asserted-by":"crossref","DOI":"10.1007\/s00251-017-0995-5","article-title":"A new mutation site in the AIRE gene causes autoimmune polyendocrine syndrome type 1","author":"Zhu","year":"2017","journal-title":"Immunogenetics"},{"key":"10.1016\/j.autrev.2017.11.012_bb0015","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.humimm.2016.06.002","article-title":"AIRE genetic variants and predisposition to polygenic autoimmune disease: the case of Graves' disease and a systematic literature review","volume":"77","author":"Colobran","year":"2016","journal-title":"Hum Immunol"},{"key":"10.1016\/j.autrev.2017.11.012_bb0020","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.autrev.2005.09.001","article-title":"Disruption of immunological tolerance: role of AIRE gene in autoimmunity","volume":"5","author":"Rizzi","year":"2006","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.autrev.2017.11.012_bb0025","doi-asserted-by":"crossref","first-page":"2975","DOI":"10.1210\/jc.2016-1821","article-title":"A longitudinal follow-up of autoimmune polyendocrine syndrome type 1","volume":"101","author":"Bruserud","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.autrev.2017.11.012_bb0030","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1530\/EC-17-0022","article-title":"Autoimmune polyendocrine syndrome type 1 in an Indian cohort: a longitudinal study","volume":"6","author":"Zaidi","year":"2017","journal-title":"Endocr Connect"},{"key":"10.1016\/j.autrev.2017.11.012_bb0035","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.clim.2014.12.007","article-title":"Fetal-onset IPEX: report of two families and review of literature","volume":"156","author":"Xavier-da-Silva","year":"2015","journal-title":"Clin Immunol"},{"key":"10.1016\/j.autrev.2017.11.012_bb0040","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.autrev.2014.10.016","article-title":"Autoimmune thyroid disorders","volume":"14","author":"Antonelli","year":"2015","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.autrev.2017.11.012_bb0045","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.jaut.2016.06.020","article-title":"The critical role of epigenetics in systemic lupus erythematosus and autoimmunity","volume":"74","author":"Long","year":"2016","journal-title":"J Autoimmun"},{"key":"10.1016\/j.autrev.2017.11.012_bb0050","doi-asserted-by":"crossref","first-page":"215","DOI":"10.3109\/08916934.2013.844794","article-title":"Epigenetic dysregulation in systemic lupus erythematosus","volume":"47","author":"Liu","year":"2014","journal-title":"Autoimmunity"},{"key":"10.1016\/j.autrev.2017.11.012_bb0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jaut.2017.04.002","article-title":"Immune dysregulation in immunodeficiency disorders: the role of T-cell receptor sequencing","volume":"80","author":"Wong","year":"2017","journal-title":"J Autoimmun"},{"key":"10.1016\/j.autrev.2017.11.012_bb0060","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1097\/MOP.0000000000000157","article-title":"Human T follicular helper cells in primary immunodeficiencies","volume":"26","author":"Ma","year":"2014","journal-title":"Curr Opin Pediatr"},{"key":"10.1016\/j.autrev.2017.11.012_bb0065","doi-asserted-by":"crossref","first-page":"4","DOI":"10.4161\/gmic.19320","article-title":"The role of gut microbiota in immune homeostasis and autoimmunity","volume":"3","author":"HJ","year":"2012","journal-title":"Gut Microbes"},{"key":"10.1016\/j.autrev.2017.11.012_bb0070","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1016\/j.autrev.2015.05.008","article-title":"Epigenetics in autoimmune diseases: pathogenesis and prospects for therapy","volume":"14","author":"Zhang","year":"2015","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.autrev.2017.11.012_bb0075","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.jaut.2016.07.007","article-title":"CD8+ T cells drive autoimmune hematopoietic stem cell dysfunction and bone marrow failure","volume":"75","author":"Gravano","year":"2016","journal-title":"J Autoimmun"},{"key":"10.1016\/j.autrev.2017.11.012_bb0080","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jaut.2017.03.008","article-title":"Regulation of type I interferon signaling in immunity and inflammation: a comprehensive review","volume":"83","author":"Chen","year":"2017","journal-title":"J Autoimmun"},{"key":"10.1016\/j.autrev.2017.11.012_bb0085","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/j.autrev.2016.03.002","article-title":"The key culprit in the pathogenesis of systemic lupus erythematosus: aberrant DNA methylation","volume":"15","author":"Wu","year":"2016","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.autrev.2017.11.012_bb0090","first-page":"228","article-title":"Chronic tetany and chronic mycelial stomatitis in a child aged four and one-half years","volume":"38","author":"Thorpe","year":"1929","journal-title":"Am J Dis Child"},{"key":"10.1016\/j.autrev.2017.11.012_bb0095","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1210\/jcem-6-7-493","article-title":"Chronic idiopathic hypoparathyroidism with superimposed Addison's disease in a child","volume":"6","author":"Leonard","year":"1946","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.autrev.2017.11.012_bb0100","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/ng0994-83","article-title":"An autosomal locus causing autoimmune disease: autoimmune polyglandular disease type I assigned to chromosome 21","volume":"8","author":"Aaltonen","year":"1994","journal-title":"Nat Genet"},{"key":"10.1016\/j.autrev.2017.11.012_bb0105","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1038\/ng1297-393","article-title":"Positional cloning of the APECED gene","volume":"17","author":"Nagamine","year":"1997","journal-title":"Nat Genet"},{"key":"10.1016\/j.autrev.2017.11.012_bb0110","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1097\/00005792-198109000-00003","article-title":"Two types of autoimmune Addison's disease associated with different polyglandular autoimmune (PGA) syndromes","volume":"60","author":"Neufeld","year":"1981","journal-title":"Medicine"},{"key":"10.1016\/j.autrev.2017.11.012_bb0115","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1093\/hmg\/11.4.397","article-title":"Aire deficient mice develop multiple features of APECED phenotype and show altered immune response","volume":"11","author":"Ramsey","year":"2002","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.autrev.2017.11.012_bb0120","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1056\/NEJM199006283222601","article-title":"Clinical variation of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) in a series of 68 patients","volume":"322","author":"Ahonen","year":"1990","journal-title":"N Engl J Med"},{"key":"10.1016\/j.autrev.2017.11.012_bb0125","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1016\/0140-6736(92)91894-E","article-title":"Identification by molecular cloning of an autoantigen associated with Addison's disease as steroid 17 alpha-hydroxylase","volume":"339","author":"Krohn","year":"1992","journal-title":"Lancet"},{"key":"10.1016\/j.autrev.2017.11.012_bb0130","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1016\/0140-6736(92)91829-W","article-title":"21-Hydroxylase, a major autoantigen in idiopathic Addison's disease","volume":"339","author":"Winqvist","year":"1992","journal-title":"Lancet"},{"key":"10.1016\/j.autrev.2017.11.012_bb0135","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.88782","article-title":"Redefined clinical features and diagnostic criteria in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy","volume":"1","author":"Ferre","year":"2016","journal-title":"JCI Insight"},{"key":"10.1016\/j.autrev.2017.11.012_bb0140","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1210\/jc.2011-2461","article-title":"Autoimmune polyendocrine syndrome type 1: an extensive longitudinal study in Sardinian patients","volume":"97","author":"Meloni","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.autrev.2017.11.012_bb0145","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1159\/000297714","article-title":"Autoimmune polyendocrine syndrome type 1 in north-western France: AIRE gene mutation specificities and severe forms needing immunosuppressive therapies","volume":"74","author":"Proust-Lemoine","year":"2010","journal-title":"Horm Res Paediatr"},{"key":"10.1016\/j.autrev.2017.11.012_bb0150","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1016\/j.immuni.2015.04.021","article-title":"Dominant mutations in the autoimmune regulator aire are associated with common organ-specific autoimmune diseases","volume":"42","author":"Oftedal","year":"2015","journal-title":"Immunity"},{"key":"10.1016\/j.autrev.2017.11.012_bb0155","doi-asserted-by":"crossref","first-page":"86","DOI":"10.3389\/fped.2016.00086","article-title":"Novel findings into aire genetics and functioning: clinical implications","volume":"4","author":"De Martino","year":"2016","journal-title":"Front Pediatr"},{"key":"10.1016\/j.autrev.2017.11.012_bb0160","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1007\/s12098-013-1201-x","article-title":"Recurrent oral thrush","volume":"81","author":"Sivabalan","year":"2014","journal-title":"Indian J Pediatr"},{"key":"10.1016\/j.autrev.2017.11.012_bb0165","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2013-203202","article-title":"Severe systemic candidiasis following immunomodulation therapy in in vitro fertilisation-embryo transfer (IVF-ET)","volume":"2014","author":"Akhanoba","year":"2014","journal-title":"BMJ Case Rep"},{"key":"10.1016\/j.autrev.2017.11.012_bb0170","first-page":"172","article-title":"Review of hypoparathyroidism","volume":"7","author":"Abate","year":"2016","journal-title":"Front Endocrinol"},{"key":"10.1016\/j.autrev.2017.11.012_bb0175","doi-asserted-by":"crossref","first-page":"258","DOI":"10.7861\/clinmedicine.17-3-258","article-title":"Adrenal insufficiency \u2013 recognition and management","volume":"17","author":"Pazderska","year":"2017","journal-title":"Clin Med"},{"key":"10.1016\/j.autrev.2017.11.012_bb0180","doi-asserted-by":"crossref","first-page":"166","DOI":"10.4103\/0378-6323.152285","article-title":"Psoriasis in autoimmune polyendocrine syndrome type I: a possible complication or a non-endocrine minor component?","volume":"81","author":"Poojary","year":"2015","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"10.1016\/j.autrev.2017.11.012_bb0185","first-page":"55","article-title":"Specific clinical features of type 1 autoimmune polyglandular syndrome","volume":"93","author":"Mikhina","year":"2015","journal-title":"Klin Med"},{"key":"10.1016\/j.autrev.2017.11.012_bb0190","doi-asserted-by":"crossref","first-page":"2843","DOI":"10.1210\/jc.2005-2611","article-title":"Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy","volume":"91","author":"Perheentupa","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.autrev.2017.11.012_bb0195","article-title":"Delayed diagnosis with autoimmune polyglandular syndrome type 2 causing acute adrenal crisis: a case report","volume":"95","author":"Wang","year":"2016","journal-title":"Medicine"},{"key":"10.1016\/j.autrev.2017.11.012_bb0200","doi-asserted-by":"crossref","first-page":"331","DOI":"10.3389\/fimmu.2013.00331","article-title":"APECED: a paradigm of complex interactions between genetic background and susceptibility factors","volume":"4","author":"De Martino","year":"2013","journal-title":"Front Immunol"},{"key":"10.1016\/j.autrev.2017.11.012_bb0205","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.autrev.2010.08.019","article-title":"Recent insights into the role and molecular mechanisms of the autoimmune regulator (AIRE) gene in autoimmunity","volume":"10","author":"Fierabracci","year":"2011","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.autrev.2017.11.012_bb0210","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.coi.2016.07.003","article-title":"AIRE-mutations and autoimmune disease","volume":"43","author":"Bruserud","year":"2016","journal-title":"Curr Opin Immunol"},{"key":"10.1016\/j.autrev.2017.11.012_bb0215","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1002\/humu.20224","article-title":"Functional analysis of SAND mutations in AIRE supports dominant inheritance of the G228W mutation","volume":"26","author":"Ilmarinen","year":"2005","journal-title":"Hum Mutat"},{"key":"10.1016\/j.autrev.2017.11.012_bb0220","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1111\/j.1399-0004.2006.00690.x","article-title":"Molecular background of polyendocrinopathy-candidiasis-ectodermal dystrophy syndrome in a Polish population: novel AIRE mutations and an estimate of disease prevalence","volume":"70","author":"Stolarski","year":"2006","journal-title":"Clin Genet"},{"key":"10.1016\/j.autrev.2017.11.012_bb0225","doi-asserted-by":"crossref","first-page":"675","DOI":"10.7754\/Clin.Lab.2012.120803","article-title":"Peculiar genotypes of the autoimmune regulator gene in Italian patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy syndrome","volume":"59","author":"Palma","year":"2013","journal-title":"Clin Lab"},{"key":"10.1016\/j.autrev.2017.11.012_bb0230","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1007\/s00431-014-2448-6","article-title":"Hypoparathyroidism and central diabetes insipidus: in search of the link","volume":"173","author":"Eyal","year":"2014","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.autrev.2017.11.012_bb0235","doi-asserted-by":"crossref","first-page":"11313","DOI":"10.1074\/jbc.M116.722488","article-title":"Functional domains of autoimmune regulator (AIRE) modulate INS-VNTR transcription in human thymic epithelial cells","volume":"291","author":"Sparks","year":"2016","journal-title":"J Biol Chem"},{"key":"10.1016\/j.autrev.2017.11.012_bb0240","doi-asserted-by":"crossref","first-page":"133","DOI":"10.2177\/jsci.37.133","article-title":"Function of Aire in central and peripheral immune tolerance","volume":"37","author":"Hanafusa","year":"2014","journal-title":"Jpn J Clin Immunol"},{"key":"10.1016\/j.autrev.2017.11.012_bb0245","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1038\/nri.2016.9","article-title":"AIRE expands: new roles in immune tolerance and beyond","volume":"16","author":"Anderson","year":"2016","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.autrev.2017.11.012_bb0250","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.jaut.2012.11.004","article-title":"AIRE expressing marginal zone dendritic cells balances adaptive immunity and T-follicular helper cell recruitment","volume":"42","author":"Lindmark","year":"2013","journal-title":"J Autoimmun"},{"key":"10.1016\/j.autrev.2017.11.012_bb0255","first-page":"352","article-title":"The thymic orchestration involving Aire, miRNAs, and cell-cell interactions during the induction of central tolerance","volume":"6","author":"Passos","year":"2015","journal-title":"Front Immunol"},{"key":"10.1016\/j.autrev.2017.11.012_bb0260","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1016\/j.cell.2015.10.057","article-title":"Aire gets company for immune tolerance","volume":"163","author":"Klein","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.autrev.2017.11.012_bb0265","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.gene.2013.08.015","article-title":"Regulation of human autoimmune regulator (AIRE) gene translation by miR-220b","volume":"530","author":"Matsuo","year":"2013","journal-title":"Gene"},{"key":"10.1016\/j.autrev.2017.11.012_bb0270","first-page":"615","article-title":"Editorial: the role of Aire, microRNAs and cell-cell interactions on thymic architecture and induction of tolerance","volume":"6","author":"Passos","year":"2015","journal-title":"Front Immunol"},{"key":"10.1016\/j.autrev.2017.11.012_bb0275","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/j.cell.2015.10.013","article-title":"Fezf2 orchestrates a thymic program of self-antigen expression for immune tolerance","volume":"163","author":"Takaba","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.autrev.2017.11.012_bb0280","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1515\/cclm-2016-0615","article-title":"Assessment of autoantibodies to interferon-omega in patients with autoimmune polyendocrine syndrome type 1: using a new immunoprecipitation assay","volume":"55","author":"Larosa","year":"2017","journal-title":"Clin Chem Lab Med"},{"key":"10.1016\/j.autrev.2017.11.012_bb0285","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.cell.2016.06.024","article-title":"AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies","volume":"166","author":"Meyer","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.autrev.2017.11.012_bb0290","doi-asserted-by":"crossref","first-page":"4880","DOI":"10.4049\/jimmunol.1401467","article-title":"Two novel gain-of-function mutations of STAT1 responsible for chronic mucocutaneous candidiasis disease: impaired production of IL-17A and IL-22, and the presence of anti-IL-17F autoantibody","volume":"193","author":"Yamazaki","year":"2014","journal-title":"J Immunol"},{"key":"10.1016\/j.autrev.2017.11.012_bb0295","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1056\/NEJMoa0706487","article-title":"Autoimmune polyendocrine syndrome type 1 and NALP5, a parathyroid autoantigen","volume":"358","author":"Alimohammadi","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1016\/j.autrev.2017.11.012_bb0300","doi-asserted-by":"crossref","first-page":"146","DOI":"10.4103\/0972-2327.165462","article-title":"A unique combination of autoimmune limbic encephalitis, type 1 diabetes, and stiff person syndrome associated with GAD-65 antibody","volume":"19","author":"Sharma","year":"2016","journal-title":"Ann Indian Acad Neurol"},{"key":"10.1016\/j.autrev.2017.11.012_bb0305","doi-asserted-by":"crossref","DOI":"10.4274\/jcrpe.3818","article-title":"Autoimmune limbic encephalitis associated with type 1 diabetes mellitus","author":"Akin","year":"2017","journal-title":"J Clin Res Pediatr Endocrinol"},{"key":"10.1016\/j.autrev.2017.11.012_bb0310","doi-asserted-by":"crossref","DOI":"10.3390\/ijms17071106","article-title":"Type 1 diabetes in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy syndrome (APECED): a \u201crare\u201d manifestation in a \u201crare\u201d disease","volume":"17","author":"Fierabracci","year":"2016","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.autrev.2017.11.012_bb0315","doi-asserted-by":"crossref","DOI":"10.1038\/srep20104","article-title":"Proteome-wide survey of the autoimmune target repertoire in autoimmune polyendocrine syndrome type 1","volume":"6","author":"Landegren","year":"2016","journal-title":"Sci Rep"},{"key":"10.1016\/j.autrev.2017.11.012_bb0320","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1111\/j.1365-2796.2009.02090.x","article-title":"Clinical manifestations and management of patients with autoimmune polyendocrine syndrome type I","volume":"265","author":"Husebye","year":"2009","journal-title":"J Intern Med"},{"key":"10.1016\/j.autrev.2017.11.012_bb0325","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1507\/endocrj.EJ16-0242","article-title":"Diagnosis and treatment of adrenal insufficiency including adrenal crisis: a Japan Endocrine Society clinical practice guideline","volume":"63","author":"Yanase","year":"2016","journal-title":"Endocr J"},{"key":"10.1016\/j.autrev.2017.11.012_bb0330","doi-asserted-by":"crossref","first-page":"173","DOI":"10.5694\/mja16.00393","article-title":"Endocrine Society of Australia position statement on male hypogonadism (part 1): assessment and indications for testosterone therapy","volume":"205","author":"Yeap","year":"2016","journal-title":"Med J Aust"},{"key":"10.1016\/j.autrev.2017.11.012_bb0335","doi-asserted-by":"crossref","first-page":"51","DOI":"10.5114\/pm.2017.68592","article-title":"Premature ovarian failure","volume":"16","author":"Jankowska","year":"2017","journal-title":"Menopause Rev"},{"key":"10.1016\/j.autrev.2017.11.012_bb0340","doi-asserted-by":"crossref","first-page":"2534","DOI":"10.1056\/NEJMoa1603825","article-title":"Thyroid hormone therapy for older adults with subclinical hypothyroidism","volume":"376","author":"Stott","year":"2017","journal-title":"N Engl J Med"},{"key":"10.1016\/j.autrev.2017.11.012_bb0345","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s11892-017-0863-6","article-title":"Cell therapy for type 1 diabetes: current and future strategies","volume":"17","author":"Aghazadeh","year":"2017","journal-title":"Curr Diab Rep"},{"key":"10.1016\/j.autrev.2017.11.012_bb0350","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/ajo.12592","article-title":"Recurrent vulvovaginal candidiasis: a review of guideline recommendations","volume":"57","author":"Matheson","year":"2017","journal-title":"Aust N Z J Obstet Gynaecol"},{"key":"10.1016\/j.autrev.2017.11.012_bb0355","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1099\/jmm.0.000024","article-title":"Molecular identification and antifungal susceptibility of 186 Candida isolates from vulvovaginal candidiasis in southern China","volume":"64","author":"Shi","year":"2015","journal-title":"J Med Microbiol"},{"key":"10.1016\/j.autrev.2017.11.012_bb0360","doi-asserted-by":"crossref","first-page":"594","DOI":"10.3109\/1040841X.2014.974500","article-title":"Novel strategies to fight Candida species infection","volume":"42","author":"Rodrigues","year":"2016","journal-title":"Crit Rev Microbiol"},{"key":"10.1016\/j.autrev.2017.11.012_bb0365","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1111\/1348-0421.12195","article-title":"Immunological basis of anti-Candida vaccines focused on synthetically prepared cell wall mannan-derived manno-oligomers","volume":"58","author":"Paulovicova","year":"2014","journal-title":"Microbiol Immunol"},{"key":"10.1016\/j.autrev.2017.11.012_bb0370","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1097\/MPG.0000000000001530","article-title":"Second-line agents in pediatric patients with autoimmune hepatitis: a systematic review and meta-analysis","volume":"65","author":"Zizzo","year":"2017","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.autrev.2017.11.012_bb0375","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1007\/s10875-015-0176-y","article-title":"Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy","volume":"35","author":"Kisand","year":"2015","journal-title":"J Clin Immunol"},{"key":"10.1016\/j.autrev.2017.11.012_bb0380","doi-asserted-by":"crossref","first-page":"8","DOI":"10.3389\/fped.2017.00008","article-title":"Novel immunotherapies for autoimmune hepatitis","volume":"5","author":"Cassim","year":"2017","journal-title":"Front Pediatr"},{"key":"10.1016\/j.autrev.2017.11.012_bb0385","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1172\/JCI86800","article-title":"Estrogen turns down \u201cthe AIRE\u201d","volume":"126","author":"Bakhru","year":"2016","journal-title":"J Clin Invest"},{"key":"10.1016\/j.autrev.2017.11.012_bb0390","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1038\/nrrheum.2017.39","article-title":"Systemic sclerosis: knocking out FLI1 to clear the AIRE","volume":"13","author":"McHugh","year":"2017","journal-title":"Nat Rev Rheumatol"}],"container-title":["Autoimmunity Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568997217302859?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568997217302859?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,10,20]],"date-time":"2020-10-20T23:19:13Z","timestamp":1603235953000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1568997217302859"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":78,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["S1568997217302859"],"URL":"https:\/\/doi.org\/10.1016\/j.autrev.2017.11.012","relation":{},"ISSN":["1568-9972"],"issn-type":[{"value":"1568-9972","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The immunobiology and clinical features of type 1 autoimmune polyglandular syndrome (APS-1)","name":"articletitle","label":"Article Title"},{"value":"Autoimmunity Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.autrev.2017.11.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}