{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T14:09:46Z","timestamp":1791900586414,"version":"4.3.4"},"reference-count":183,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Autoimmunity Reviews"],"published-print":{"date-parts":[[2019,5]]},"DOI":"10.1016\/j.autrev.2019.03.009","type":"journal-article","created":{"date-parts":[[2019,3,4]],"date-time":"2019-03-04T17:36:38Z","timestamp":1551720998000},"page":"526-534","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":107,"title":["Serum and blister fluid levels of cytokines and chemokines in pemphigus and bullous pemphigoid"],"prefix":"10.1016","volume":"18","author":[{"given":"Eric H.","family":"Kowalski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Kneibner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalaf","family":"Kridin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyle T.","family":"Amber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.autrev.2019.03.009_bb0005","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1084\/jem.160.5.1509","article-title":"Human autoantibodies against a desmosomal core protein in pemphigus foliaceus","volume":"160","author":"Koulu","year":"1984","journal-title":"J Exp Med."},{"issue":"4","key":"10.1016\/j.autrev.2019.03.009_bb0010","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.4049\/jimmunol.136.4.1227","article-title":"A monoclonal antibody to the desmosomal glycoprotein desmoglein I binds the same polypeptide as human autoantibodies in pemphigus foliaceus","volume":"136","author":"Stanley","year":"1986","journal-title":"J Immunol."},{"issue":"5","key":"10.1016\/j.autrev.2019.03.009_bb0015","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/0092-8674(91)90360-B","article-title":"Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion","volume":"67","author":"Amagai","year":"1991","journal-title":"Cell."},{"issue":"10","key":"10.1016\/j.autrev.2019.03.009_bb0020","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1056\/NEJM198909073211002","article-title":"Demonstration of an adhering-junction molecule (plakoglobin) in the autoantigens of pemphigus foliaceus and pemphigus vulgaris","volume":"321","author":"Korman","year":"1989","journal-title":"N Engl J Med."},{"issue":"3","key":"10.1016\/j.autrev.2019.03.009_bb0025","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/j.jaci.2016.08.012","article-title":"Bullous pemphigoid outcome is associated with CXCL10-induced matrix metalloproteinase 9 secretion from monocytes and neutrophils but not lymphocytes","volume":"139","author":"Riani","year":"2017","journal-title":"J Allergy Clin Immunol."},{"issue":"7","key":"10.1016\/j.autrev.2019.03.009_bb0030","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1080\/08916930600971729","article-title":"Synergistic actions of pemphigus vulgaris IgG, Fas-ligand and tumor necrosis factor-alpha during induction of basal cell shrinkage and acantholysis","volume":"39","author":"Orlov","year":"2006","journal-title":"Autoimmunity."},{"key":"10.1016\/j.autrev.2019.03.009_bb0035","doi-asserted-by":"crossref","first-page":"484","DOI":"10.3389\/fimmu.2017.00484","article-title":"Eosinophils in autoimmune diseases","volume":"8","author":"Diny","year":"2017","journal-title":"Front Immunol."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0040","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/1523-1747.ep12505711","article-title":"Bullous pemphigoid, an ultrastructural study of the inflammatory response: eosinophil, basophil and mast cell granule changes in multiple biopsies from one patient","volume":"78","author":"Dvorak","year":"1982","journal-title":"J Invest Dermatol."},{"issue":"25","key":"10.1016\/j.autrev.2019.03.009_bb0045","doi-asserted-by":"crossref","first-page":"6434","DOI":"10.1073\/pnas.1721805115","article-title":"BP180 dysfunction triggers spontaneous skin inflammation in mice","volume":"115","author":"Zhang","year":"2018","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"10","key":"10.1016\/j.autrev.2019.03.009_bb0050","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1016\/j.autrev.2018.04.008","article-title":"Paraneoplastic autoimmune multiorgan syndrome (PAMS): Beyond the single phenotype of paraneoplastic pemphigus","volume":"17","author":"Amber","year":"2018","journal-title":"Autoimmun Rev."},{"issue":"5","key":"10.1016\/j.autrev.2019.03.009_bb0055","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1016\/j.surg.2005.05.003","article-title":"Interleukin-1alpha-induced proteolytic activation of metalloproteinase-9 by human skin","volume":"138","author":"Han","year":"2005","journal-title":"Surgery."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0060","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1111\/imr.12615","article-title":"Function and regulation of IL-1\u03b1 in inflammatory diseases and cancer","volume":"281","author":"Malik","year":"2018","journal-title":"Immunol Rev."},{"key":"10.1016\/j.autrev.2019.03.009_bb0065","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1146\/annurev.immunol.021908.132612","article-title":"Immunological and inflammatory functions of the interleukin-1 family","volume":"27","author":"Dinarello","year":"2009","journal-title":"Annu Rev Immunol."},{"key":"10.1016\/j.autrev.2019.03.009_bb0070","doi-asserted-by":"crossref","first-page":"5230","DOI":"10.1038\/ncomms6230","article-title":"Interleukin-1\u03b1 released from HSV-1-infected keratinocytes acts as a functional alarmin in the skin","volume":"5","author":"Milora","year":"2014","journal-title":"Nat Commun."},{"issue":"25","key":"10.1016\/j.autrev.2019.03.009_bb0075","doi-asserted-by":"crossref","first-page":"11874","DOI":"10.1073\/pnas.92.25.11874","article-title":"Inflammatory skin disease in transgenic mice that express high levels of interleukin 1 alpha in basal epidermis","volume":"92","author":"Groves","year":"1995","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0080","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1087-0024.2004.00841.x","article-title":"Bullous pemphigoid: using animal models to study the immunopathology","volume":"9","author":"Liu","year":"2004","journal-title":"J Investig Dermatol Symp Proc."},{"issue":"4","key":"10.1016\/j.autrev.2019.03.009_bb0085","first-page":"995","article-title":"92-kd gelatinase is actively expressed by eosinophils and stored by neutrophils in squamous cell carcinoma","volume":"142","author":"St\u00e5hle-B\u00e4ckdahl","year":"1993","journal-title":"Am J Pathol."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0090","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0923-1811(98)00074-7","article-title":"Endogenous neutralizing anti-IL-1 alpha autoantibodies in inflammatory skin diseases: possible natural inhibitor for over expressed epidermal IL-1","volume":"20","author":"Mizutani","year":"1998","journal-title":"J Dermatol Sci."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0095","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/0923-1811(95)00435-1","article-title":"Detection of IL-1 alpha, IL-1 beta and IL-1 receptor antagonist in blister fluid of bullous pemphigoid","volume":"11","author":"Schmidt","year":"1996","journal-title":"J Dermatol Sci."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0100","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1177\/205873929901200202","article-title":"A Th2-like cytokine response is involved in bullous pemphigoid. the role of IL-4 and IL-5 in the pathogenesis of the disease","volume":"12","author":"Feliciani","year":"1999","journal-title":"Int J Immunopathol Pharmacol."},{"issue":"4","key":"10.1016\/j.autrev.2019.03.009_bb0105","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1080\/000155500750012162","article-title":"Increased coexpression of eotaxin and interleukin 5 in bullous pemphigoid","volume":"80","author":"Shrikhande","year":"2000","journal-title":"Acta Derm Venereol."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0110","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1046\/j.1365-2133.2000.03599.x","article-title":"Elevated levels of eotaxin and interleukin-5 in blister fluid of bullous pemphigoid: correlation with tissue eosinophilia","volume":"143","author":"Wakugawa","year":"2000","journal-title":"Br J Dermatol."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0115","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1006\/cyto.2000.0791","article-title":"Bullous pemphigoid: interaction of interleukin 5, anti-basement membrane zone antibodies and eosinophils. A preliminary observation","volume":"13","author":"Engineer","year":"2001","journal-title":"Cytokine."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0120","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.clim.2006.03.014","article-title":"Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines","volume":"120","author":"Gounni Abdelilah","year":"2006","journal-title":"Clin Immunol."},{"issue":"4","key":"10.1016\/j.autrev.2019.03.009_bb0125","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1046\/j.1365-2133.1998.02169.x","article-title":"Cytokine pattern in blister fluid and serum of patients with bullous pemphigoid: relationships with disease intensity","volume":"138","author":"Ameglio","year":"1998","journal-title":"Br J Dermatol."},{"issue":"3","key":"10.1016\/j.autrev.2019.03.009_bb0130","first-page":"897","article-title":"Deposition of eosinophil granule proteins precedes blister formation in bullous pemphigoid. Comparison with neutrophil and mast cell granule proteins","volume":"148","author":"Borrego","year":"1996","journal-title":"Am J Pathol."},{"issue":"12","key":"10.1016\/j.autrev.2019.03.009_bb0135","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1111\/exd.13782","article-title":"Mechanisms of pathogenic effects of eosinophil cationic protein and eosinophil-derived neurotoxin on human keratinocytes","volume":"27","author":"Amber","year":"2018","journal-title":"Exp Dermatol."},{"issue":"7","key":"10.1016\/j.autrev.2019.03.009_bb0140","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1111\/all.13131","article-title":"Evidence for a role of eosinophils in blister formation in bullous pemphigoid","volume":"72","author":"de Graauw","year":"2017","journal-title":"Allergy."},{"issue":"1-2","key":"10.1016\/j.autrev.2019.03.009_bb0145","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s004030050272","article-title":"IL-5 levels in the serum and blister fluid of patients with bullous pemphigoid: correlations with eosinophil cationic protein, RANTES, IgE and disease severity","volume":"290","author":"D'Auria","year":"1998","journal-title":"Arch Dermatol Res."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0150","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1084\/jem.179.2.703","article-title":"Interleukin 5 synthesis by eosinophils: association with granules and immunoglobulin-dependent secretion","volume":"179","author":"Dubucquoi","year":"1994","journal-title":"J Exp Med."},{"issue":"5","key":"10.1016\/j.autrev.2019.03.009_bb0155","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1165\/ajrcmb.10.5.8179909","article-title":"Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines","volume":"10","author":"Bradding","year":"1994","journal-title":"Am J Respir Cell Mol Biol."},{"key":"10.1016\/j.autrev.2019.03.009_bb0160","doi-asserted-by":"crossref","first-page":"49","DOI":"10.3389\/fmed.2018.00049","article-title":"Targeting the Interleukin-5 Pathway for Treatment of Eosinophilic Conditions Other than Asthma","volume":"5","author":"Roufosse","year":"2018","journal-title":"Front Med (Lausanne)."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0165","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1111\/j.1365-2249.2011.04464.x","article-title":"Up-regulation of CCL11 and CCL26 is associated with activated eosinophils in bullous pemphigoid","volume":"166","author":"G\u00fcnther","year":"2011","journal-title":"Clin Exp Immunol."},{"issue":"3","key":"10.1016\/j.autrev.2019.03.009_bb0170","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/S0091-6749(03)01798-6","article-title":"Chemokine receptor expression on human eosinophils from peripheral blood and bronchoalveolar lavage fluid after segmental antigen challenge","volume":"112","author":"Liu","year":"2003","journal-title":"J Allergy Clin Immunol."},{"key":"10.1016\/j.autrev.2019.03.009_bb0175","doi-asserted-by":"crossref","first-page":"570","DOI":"10.3389\/fimmu.2014.00570","article-title":"Eosinophil cytokines, chemokines, and growth factors: emerging roles in immunity","volume":"5","author":"Davoine","year":"2014","journal-title":"Front Immunol."},{"issue":"3","key":"10.1016\/j.autrev.2019.03.009_bb0180","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.4049\/jimmunol.163.3.1602","article-title":"A novel human CC chemokine, eotaxin-3, which is expressed in IL-4-stimulated vascular endothelial cells, exhibits potent activity toward eosinophils","volume":"163","author":"Shinkai","year":"1999","journal-title":"J Immunol."},{"issue":"11","key":"10.1016\/j.autrev.2019.03.009_bb0185","doi-asserted-by":"crossref","first-page":"6321","DOI":"10.4049\/jimmunol.163.11.6321","article-title":"Eosinophil chemotactic chemokines (eotaxin, eotaxin-2, RANTES, monocyte chemoattractant protein-3 (MCP-3), and MCP-4), and C-C chemokine receptor 3 expression in bronchial biopsies from atopic and nonatopic (Intrinsic) asthmatics","volume":"163","author":"Ying","year":"1999","journal-title":"J Immunol."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0190","first-page":"27","article-title":"Increased expression of eotaxin and its specific receptor CCR3 in bullous pemphigoid","volume":"12","author":"Frezzolini","year":"2002","journal-title":"Eur J Dermatol."},{"issue":"4","key":"10.1016\/j.autrev.2019.03.009_bb0195","doi-asserted-by":"crossref","first-page":"464","DOI":"10.2340\/00015555-2581","article-title":"Increased Activity and Apoptosis of Eosinophils in Blister Fluids, Skin and Peripheral Blood of Patients with Bullous Pemphigoid","volume":"97","author":"Engmann","year":"2017","journal-title":"Acta Derm Venereol."},{"issue":"12","key":"10.1016\/j.autrev.2019.03.009_bb0200","doi-asserted-by":"crossref","first-page":"2908","DOI":"10.1038\/jid.2014.263","article-title":"Innate immune cell-produced IL-17 sustains inflammation in bullous pemphigoid","volume":"134","author":"Le Jan","year":"2014","journal-title":"J Invest Dermatol."},{"key":"10.1016\/j.autrev.2019.03.009_bb0205","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.3389\/fimmu.2017.01752","article-title":"BP180 is critical in the autoimmunity of Bullous Pemphigoid","volume":"8","author":"Liu","year":"2017","journal-title":"Front Immunol."},{"issue":"9","key":"10.1016\/j.autrev.2019.03.009_bb0210","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/S0161-5890(02)00210-9","article-title":"The two faces of IL-6 on Th1\/Th2 differentiation","volume":"39","author":"Diehl","year":"2002","journal-title":"Mol Immunol."},{"issue":"5","key":"10.1016\/j.autrev.2019.03.009_bb0215","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1038\/ni.3153","article-title":"IL-6 as a keystone cytokine in health and disease","volume":"16","author":"Hunter","year":"2015","journal-title":"Nat Immunol."},{"key":"10.1016\/j.autrev.2019.03.009_bb0220","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.coi.2018.09.002","article-title":"IL-6: a cytokine at the crossroads of autoimmunity","volume":"55","author":"Jones","year":"2018","journal-title":"Curr Opin Immunol."},{"issue":"7090","key":"10.1016\/j.autrev.2019.03.009_bb0225","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1038\/nature04753","article-title":"Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells","volume":"441","author":"Bettelli","year":"2006","journal-title":"Nature."},{"issue":"9","key":"10.1016\/j.autrev.2019.03.009_bb0230","doi-asserted-by":"crossref","first-page":"3087","DOI":"10.4049\/jimmunol.1701179","article-title":"Relative contributions of B cells and dendritic cells from Lupus-Prone Mice to CD4","volume":"200","author":"Choi","year":"2018","journal-title":"J Immunol."},{"key":"10.1016\/j.autrev.2019.03.009_bb0235","doi-asserted-by":"crossref","first-page":"201","DOI":"10.3389\/fmed.2018.00201","article-title":"The role of Eosinophils in Bullous Pemphigoid: a developing model of Eosinophil pathogenicity in Mucocutaneous disease","volume":"5","author":"Amber","year":"2018","journal-title":"Front Med (Lausanne)."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0240","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/S0923-1811(97)00044-3","article-title":"Increased serum levels of interleukin (IL)-5, IL-6 and IL-8 in bullous pemphigoid","volume":"16","author":"Inaoki","year":"1998","journal-title":"J Dermatol Sci."},{"issue":"12","key":"10.1016\/j.autrev.2019.03.009_bb0245","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1038\/s41577-018-0066-7","article-title":"Recent insights into targeting the IL-6 cytokine family in inflammatory diseases and cancer","volume":"18","author":"Jones","year":"2018","journal-title":"Nat Rev Immunol."},{"issue":"4","key":"10.1016\/j.autrev.2019.03.009_bb0250","first-page":"869","article-title":"Modulation of keratinocyte-derived interleukin-8 which is chemotactic for neutrophils and T lymphocytes","volume":"139","author":"Barker","year":"1991","journal-title":"Am J Pathol."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0255","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1111\/1523-1747.ep12556058","article-title":"Neutrophil-activating proteins in psoriasis","volume":"98","author":"Schr\u00f6der","year":"1992","journal-title":"J Invest Dermatol."},{"issue":"6","key":"10.1016\/j.autrev.2019.03.009_bb0260","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1165\/rcmb.2005-0303OC","article-title":"Eosinophil trans-basement membrane migration induced by interleukin-8 and neutrophils","volume":"34","author":"Kikuchi","year":"2006","journal-title":"Am J Respir Cell Mol Biol."},{"issue":"5","key":"10.1016\/j.autrev.2019.03.009_bb0265","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1046\/j.1523-1747.2000.00141.x","article-title":"Autoantibodies to BP180 associated with bullous pemphigoid release interleukin-6 and interleukin-8 from cultured human keratinocytes","volume":"115","author":"Schmidt","year":"2000","journal-title":"J Invest Dermatol."},{"issue":"8","key":"10.1016\/j.autrev.2019.03.009_bb0270","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1111\/j.1600-0625.2012.01529.x","article-title":"Collagen XVII (BP180) modulates keratinocyte expression of the proinflammatory chemokine, IL-8","volume":"21","author":"Van den Bergh","year":"2012","journal-title":"Exp Dermatol."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0275","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1046\/j.1365-2249.2001.01503.x","article-title":"The IL-8 release from cultured human keratinocytes, mediated by antibodies to bullous pemphigoid autoantigen 180, is inhibited by dapsone","volume":"124","author":"Schmidt","year":"2001","journal-title":"Clin Exp Immunol."},{"issue":"6","key":"10.1016\/j.autrev.2019.03.009_bb0280","doi-asserted-by":"crossref","first-page":"3064","DOI":"10.4049\/jimmunol.161.6.3064","article-title":"Triple role of platelet-activating factor in eosinophil migration across monolayers of lung epithelial cells: eosinophil chemoattractant and priming agent and epithelial cell activator","volume":"161","author":"Liu","year":"1998","journal-title":"J Immunol."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0285","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/0091-6749(93)90099-2","article-title":"Effects of nedocromil sodium on in vitro induced migration, activation, and mediator release from human granulocytes","volume":"92","author":"Bruijnzeel","year":"1993","journal-title":"J Allergy Clin Immunol."},{"key":"10.1016\/j.autrev.2019.03.009_bb0290","doi-asserted-by":"crossref","first-page":"488","DOI":"10.3389\/fimmu.2018.00488","article-title":"Tissue destruction in Bullous Pemphigoid can be complement independent and may be mitigated by C5aR2","volume":"9","author":"Karsten","year":"2018","journal-title":"Front Immunol."},{"issue":"5","key":"10.1016\/j.autrev.2019.03.009_bb0295","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1111\/all.13376","article-title":"Monocytes enhance neutrophil-induced blister formation in an ex vivo model of bullous pemphigoid","volume":"73","author":"de Graauw","year":"2018","journal-title":"Allergy."},{"issue":"6028","key":"10.1016\/j.autrev.2019.03.009_bb0300","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1038\/316552a0","article-title":"Identity of tumour necrosis factor and the macrophage-secreted factor cachectin","volume":"316","author":"Beutler","year":"1985","journal-title":"Nature."},{"issue":"5","key":"10.1016\/j.autrev.2019.03.009_bb0305","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1084\/jem.168.5.1539","article-title":"Production of tumor necrosis factor\/cachectin by human B cell lines and tonsillar B cells","volume":"168","author":"Sung","year":"1988","journal-title":"J Exp Med."},{"issue":"6","key":"10.1016\/j.autrev.2019.03.009_bb0310","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1084\/jem.165.6.1581","article-title":"Independent regulation of tumor necrosis factor and lymphotoxin production by human peripheral blood lymphocytes","volume":"165","author":"Cuturi","year":"1987","journal-title":"J Exp Med."},{"issue":"3","key":"10.1016\/j.autrev.2019.03.009_bb0315","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1172\/JCI113133","article-title":"Effects of human interleukin 1 and human tumor necrosis factor on human T lymphocyte colony formation","volume":"80","author":"Zucali","year":"1987","journal-title":"J Clin Invest."},{"issue":"5","key":"10.1016\/j.autrev.2019.03.009_bb0320","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1007\/BF00191442","article-title":"Expression of matrix metalloproteinase 9 (92-kDa gelatinase\/type IV collagenase) induced by tumour necrosis factor alpha correlates with metastatic ability in a human osteosarcoma cell line","volume":"424","author":"Kawashima","year":"1994","journal-title":"Virchows Arch."},{"issue":"5","key":"10.1016\/j.autrev.2019.03.009_bb0325","doi-asserted-by":"crossref","first-page":"2327","DOI":"10.4049\/jimmunol.158.5.2327","article-title":"Cytokine and chemokine regulation of proMMP-9 and TIMP-1 production by human peripheral blood lymphocytes","volume":"158","author":"Johnatty","year":"1997","journal-title":"J Immunol."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0330","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/0006-291X(86)90881-8","article-title":"Tumor necrosis factor stimulates interleukin-1 and prostaglandin E2 production in resting macrophages","volume":"136","author":"Bachwich","year":"1986","journal-title":"Biochem Biophys Res Commun."},{"issue":"5","key":"10.1016\/j.autrev.2019.03.009_bb0335","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1172\/JCI112721","article-title":"Cachectin\/tumor necrosis factor regulates hepatic acute-phase gene expression","volume":"78","author":"Perlmutter","year":"1986","journal-title":"J Clin Invest."},{"issue":"5","key":"10.1016\/j.autrev.2019.03.009_bb0340","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1002\/eji.1830180513","article-title":"Action of recombinant human interleukin 6, interleukin 1 beta and tumor necrosis factor alpha on the mRNA induction of acute-phase proteins","volume":"18","author":"Andus","year":"1988","journal-title":"Eur J Immunol."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0345","doi-asserted-by":"crossref","first-page":"60","DOI":"10.4049\/jimmunol.160.1.60","article-title":"IL-4 induces eotaxin: a possible mechanism of selective eosinophil recruitment in helminth infection and atopy","volume":"160","author":"Mochizuki","year":"1998","journal-title":"J Immunol."},{"issue":"6083","key":"10.1016\/j.autrev.2019.03.009_bb0350","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1038\/323079a0","article-title":"Recombinant human TNF induces production of granulocyte-monocyte colony-stimulating factor","volume":"323","author":"Munker","year":"1986","journal-title":"Nature."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0355","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0014-5793(99)01717-2","article-title":"The role of p38 mitogen-activated protein kinase in IL-6 and IL-8 production from the TNF-alpha- or IL-1beta-stimulated rheumatoid synovial fibroblasts","volume":"465","author":"Suzuki","year":"2000","journal-title":"FEBS Lett."},{"issue":"18","key":"10.1016\/j.autrev.2019.03.009_bb0360","doi-asserted-by":"crossref","first-page":"6802","DOI":"10.1073\/pnas.85.18.6802","article-title":"Enhancement of cAMP levels and of protein kinase activity by tumor necrosis factor and interleukin 1 in human fibroblasts: role in the induction of interleukin 6","volume":"85","author":"Zhang","year":"1988","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"9","key":"10.1016\/j.autrev.2019.03.009_bb0365","doi-asserted-by":"crossref","first-page":"2970","DOI":"10.4049\/jimmunol.139.9.2970","article-title":"Enhancement of human B cell proliferation and differentiation by tumor necrosis factor-alpha and interleukin 1","volume":"139","author":"Jelinek","year":"1987","journal-title":"J Immunol."},{"issue":"3","key":"10.1016\/j.autrev.2019.03.009_bb0370","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1016\/S0006-291X(88)80779-4","article-title":"Monokine-induced gene expression of a human endothelial cell-derived neutrophil chemotactic factor","volume":"156","author":"Strieter","year":"1988","journal-title":"Biochem Biophys Res Commun."},{"issue":"6","key":"10.1016\/j.autrev.2019.03.009_bb0375","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.4049\/jimmunol.139.6.1935","article-title":"Induction of interleukin 2 receptor (TAC) by tumor necrosis factor in YT cells","volume":"139","author":"Lee","year":"1987","journal-title":"J Immunol."},{"issue":"3","key":"10.1016\/j.autrev.2019.03.009_bb0380","doi-asserted-by":"crossref","first-page":"e102","DOI":"10.1016\/j.jaad.2014.04.008","article-title":"A 52-year-old man with bullous pemphigoid and bullous cystitis","volume":"71","author":"Launhardt","year":"2014","journal-title":"J Am Acad Dermatol."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0385","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1346-8138.2012.01659.x","article-title":"Case of coexisting psoriatic arthritis and bullous pemphigoid improved by etanercept","volume":"40","author":"Nin","year":"2013","journal-title":"J Dermatol."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0390","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jdcr.2015.12.006","article-title":"Etanercept-induced generalization of chronic, localized, anogenital bullous pemphigoid in a psoriatic patient","volume":"2","author":"Wilmer","year":"2016","journal-title":"JAAD Case Rep."},{"issue":"4","key":"10.1016\/j.autrev.2019.03.009_bb0395","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.jdcr.2017.03.008","article-title":"Adalimumab-associated bullous pemphigoid in a patient with ulcerative colitis","volume":"3","author":"Wessman","year":"2017","journal-title":"JAAD Case Rep."},{"issue":"12","key":"10.1016\/j.autrev.2019.03.009_bb0400","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1007\/s00384-014-1924-9","article-title":"Bullous pemphigoid occurring under anti-tumor necrosis factor-\u03b1 therapy","volume":"29","author":"Ricci","year":"2014","journal-title":"Int J Colorectal Dis."},{"issue":"7","key":"10.1016\/j.autrev.2019.03.009_bb0405","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1111\/1346-8138.12171","article-title":"Pemphigoid nodularis possibly induced by etanercept","volume":"40","author":"Mochizuki","year":"2013","journal-title":"J Dermatol."},{"issue":"8","key":"10.1016\/j.autrev.2019.03.009_bb0410","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1111\/j.1365-2230.2011.04102.x","article-title":"Drug-induced bullous pemphigoid: cases triggered by intravenous iodine and etanercept","volume":"36","author":"Kluk","year":"2011","journal-title":"Clin Exp Dermatol."},{"issue":"3","key":"10.1016\/j.autrev.2019.03.009_bb0415","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1159\/000318008","article-title":"Autoimmune bullous skin diseases occurring under anti-tumor necrosis factor therapy: two case reports","volume":"221","author":"Boussemart","year":"2010","journal-title":"Dermatology."},{"issue":"Suppl. 2","key":"10.1016\/j.autrev.2019.03.009_bb0420","doi-asserted-by":"crossref","first-page":"S121","DOI":"10.1016\/j.jaad.2005.10.055","article-title":"Treatment of coexisting bullous pemphigoid and psoriasis with the tumor necrosis factor antagonist etanercept","volume":"54","author":"Yamauchi","year":"2006","journal-title":"J Am Acad Dermatol."},{"issue":"4","key":"10.1016\/j.autrev.2019.03.009_bb0425","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1159\/000243805","article-title":"Bullous pemphigoid during long-term TNF-alpha blocker therapy","volume":"219","author":"Bordignon","year":"2009","journal-title":"Dermatology."},{"issue":"3","key":"10.1016\/j.autrev.2019.03.009_bb0430","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1093\/intimm\/6.3.463","article-title":"Role of macrophages and alpha beta T lymphocytes in early interleukin 10 production during Listeria monocytogenes infection","volume":"6","author":"Flesch","year":"1994","journal-title":"Int Immunol."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0435","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1084\/jem.20062175","article-title":"Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection","volume":"204","author":"Jankovic","year":"2007","journal-title":"J Exp Med."},{"issue":"6","key":"10.1016\/j.autrev.2019.03.009_bb0440","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1084\/jem.170.6.2081","article-title":"Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones","volume":"170","author":"Fiorentino","year":"1989","journal-title":"J Exp Med."},{"issue":"12","key":"10.1016\/j.autrev.2019.03.009_bb0445","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1038\/ni1539","article-title":"TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology","volume":"8","author":"McGeachy","year":"2007","journal-title":"Nat Immunol."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0450","doi-asserted-by":"crossref","first-page":"92","DOI":"10.4049\/jimmunol.149.1.92","article-title":"Identification and induction of keratinocyte-derived IL-10","volume":"149","author":"Enk","year":"1992","journal-title":"J Immunol."},{"issue":"9","key":"10.1016\/j.autrev.2019.03.009_bb0455","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1093\/intimm\/2.9.821","article-title":"Production of cytokines by mouse B cells: B lymphomas and normal B cells produce interleukin 10","volume":"2","author":"O'Garra","year":"1990","journal-title":"Int Immunol."},{"issue":"12","key":"10.1016\/j.autrev.2019.03.009_bb0460","doi-asserted-by":"crossref","first-page":"4859","DOI":"10.4049\/jimmunol.156.12.4859","article-title":"Constitutive production of IL-4 and IL-10 and stimulated production of IL-8 by normal peripheral blood eosinophils","volume":"156","author":"Nakajima","year":"1996","journal-title":"J Immunol."},{"issue":"11","key":"10.1016\/j.autrev.2019.03.009_bb0465","doi-asserted-by":"crossref","first-page":"3815","DOI":"10.4049\/jimmunol.147.11.3815","article-title":"IL-10 inhibits cytokine production by activated macrophages","volume":"147","author":"Fiorentino","year":"1991","journal-title":"J Immunol."},{"issue":"10","key":"10.1016\/j.autrev.2019.03.009_bb0470","doi-asserted-by":"crossref","first-page":"3444","DOI":"10.4049\/jimmunol.146.10.3444","article-title":"IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells","volume":"146","author":"Fiorentino","year":"1991","journal-title":"J Immunol."},{"issue":"5","key":"10.1016\/j.autrev.2019.03.009_bb0475","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.1073\/pnas.89.5.1890","article-title":"Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes","volume":"89","author":"Rousset","year":"1992","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0480","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1172\/JCI116977","article-title":"Interleukin-10 prevents spontaneous death of germinal center B cells by induction of the bcl-2 protein","volume":"93","author":"Levy","year":"1994","journal-title":"J Clin Invest."},{"issue":"8","key":"10.1016\/j.autrev.2019.03.009_bb0485","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1093\/intimm\/7.8.1243","article-title":"Long-term cultured CD40-activated B lymphocytes differentiate into plasma cells in response to IL-10 but not IL-4","volume":"7","author":"Rousset","year":"1995","journal-title":"Int Immunol."},{"issue":"7","key":"10.1016\/j.autrev.2019.03.009_bb0490","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1006\/cyto.1999.0642","article-title":"Presence of interleukin 10 in the serum and blister fluid of patients with pemphigus vulgaris and pemphigoid","volume":"12","author":"Bhol","year":"2000","journal-title":"Cytokine."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0495","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.4049\/jimmunol.181.2.1526","article-title":"Novel system evaluating in vivo pathogenicity of desmoglein 3-reactive T cell clones using murine pemphigus vulgaris","volume":"181","author":"Takahashi","year":"2008","journal-title":"J Immunol."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0500","doi-asserted-by":"crossref","first-page":"522","DOI":"10.4049\/jimmunol.164.1.522","article-title":"Immune modulation in pemphigus vulgaris: role of CD28 and IL-10","volume":"164","author":"Toto","year":"2000","journal-title":"J Immunol."},{"issue":"4","key":"10.1016\/j.autrev.2019.03.009_bb0505","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1046\/j.1523-1747.1998.00347.x","article-title":"Interleukin-17 and interferon-gamma synergize in the enhancement of proinflammatory cytokine production by human keratinocytes","volume":"111","author":"Teunissen","year":"1998","journal-title":"J Invest Dermatol."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0510","doi-asserted-by":"crossref","first-page":"490","DOI":"10.4049\/jimmunol.1100123","article-title":"Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis","volume":"187","author":"Lin","year":"2011","journal-title":"J Immunol."},{"issue":"11","key":"10.1016\/j.autrev.2019.03.009_bb0515","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1038\/ni1254","article-title":"Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages","volume":"6","author":"Harrington","year":"2005","journal-title":"Nat Immunol."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0520","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1084\/jem.20041257","article-title":"IL-23 drives a pathogenic T cell population that induces autoimmune inflammation","volume":"201","author":"Langrish","year":"2005","journal-title":"J Exp Med."},{"issue":"11","key":"10.1016\/j.autrev.2019.03.009_bb0525","doi-asserted-by":"crossref","first-page":"6173","DOI":"10.4049\/jimmunol.171.11.6173","article-title":"Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice","volume":"171","author":"Nakae","year":"2003","journal-title":"J Immunol."},{"issue":"5","key":"10.1016\/j.autrev.2019.03.009_bb0530","doi-asserted-by":"crossref","first-page":"2832","DOI":"10.4049\/jimmunol.164.5.2832","article-title":"High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism","volume":"164","author":"Ziolkowska","year":"2000","journal-title":"J Immunol."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0535","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1177\/135245859900500206","article-title":"Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis","volume":"5","author":"Matusevicius","year":"1999","journal-title":"Mult Scler."},{"issue":"4","key":"10.1016\/j.autrev.2019.03.009_bb0540","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1002\/art.10872","article-title":"T cells regulate the expression of matrix metalloproteinase in human osteoblasts via a dual mitogen-activated protein kinase mechanism","volume":"48","author":"Rifas","year":"2003","journal-title":"Arthritis Rheum."},{"issue":"4","key":"10.1016\/j.autrev.2019.03.009_bb0545","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1084\/jem.194.4.519","article-title":"Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense","volume":"194","author":"Ye","year":"2001","journal-title":"J Exp Med."},{"issue":"7","key":"10.1016\/j.autrev.2019.03.009_bb0550","doi-asserted-by":"crossref","first-page":"3513","DOI":"10.4049\/jimmunol.160.7.3513","article-title":"IL-17 stimulates the production and expression of proinflammatory cytokines, IL-beta and TNF-alpha, by human macrophages","volume":"160","author":"Jovanovic","year":"1998","journal-title":"J Immunol."},{"issue":"3","key":"10.1016\/j.autrev.2019.03.009_bb0555","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.jaut.2008.04.017","article-title":"Role of Th1 and Th17 cells in organ-specific autoimmunity","volume":"31","author":"Dardalhon","year":"2008","journal-title":"J Autoimmun."},{"issue":"12","key":"10.1016\/j.autrev.2019.03.009_bb0560","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1172\/JCI3335","article-title":"Identification and characterization of autoreactive T cell responses to bullous pemphigoid antigen 2 in patients and healthy controls","volume":"102","author":"B\u00fcdinger","year":"1998","journal-title":"J Clin Invest."},{"issue":"5","key":"10.1016\/j.autrev.2019.03.009_bb0565","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1172\/JCI119639","article-title":"A major role for neutrophils in experimental bullous pemphigoid","volume":"100","author":"Liu","year":"1997","journal-title":"J Clin Invest."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0570","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1046\/j.1523-1747.1998.00086.x","article-title":"Recognition of desmoglein 3 by autoreactive T cells in pemphigus vulgaris patients and normals","volume":"110","author":"Hertl","year":"1998","journal-title":"J Invest Dermatol."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0575","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1172\/JCI119130","article-title":"Development and characterization of desmoglein-3 specific T cells from patients with pemphigus vulgaris","volume":"99","author":"Lin","year":"1997","journal-title":"J Clin Invest."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0580","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1172\/JCI8075","article-title":"Desmoglein-1-specific T lymphocytes from patients with endemic pemphigus foliaceus (fogo selvagem)","volume":"105","author":"Lin","year":"2000","journal-title":"J Clin Invest."},{"issue":"23","key":"10.1016\/j.autrev.2019.03.009_bb0585","doi-asserted-by":"crossref","first-page":"15036","DOI":"10.1074\/jbc.272.23.15036","article-title":"The T cell-directed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4","volume":"272","author":"Imai","year":"1997","journal-title":"J Biol Chem."},{"issue":"5","key":"10.1016\/j.autrev.2019.03.009_bb0590","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1002\/(SICI)1521-4141(199905)29:05<1617::AID-IMMU1617>3.0.CO;2-3","article-title":"Distinct patterns and kinetics of chemokine production regulate dendritic cell function","volume":"29","author":"Sallusto","year":"1999","journal-title":"Eur J Immunol."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0595","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1007\/s00403-006-0661-5","article-title":"Both Th1 and Th2 chemokines are elevated in sera of patients with autoimmune blistering diseases","volume":"298","author":"Echigo","year":"2006","journal-title":"Arch Dermatol Res."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0600","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1046\/j.1365-2133.2003.05066.x","article-title":"High level of thymus and activation-regulated chemokine in blister fluid and sera of patients with bullous pemphigoid","volume":"148","author":"Kakinuma","year":"2003","journal-title":"Br J Dermatol."},{"issue":"6","key":"10.1016\/j.autrev.2019.03.009_bb0605","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1046\/j.1365-2133.2000.03894.x","article-title":"High levels of interleukin-8, soluble CD4 and soluble CD8 in bullous pemphigoid blister fluid. The relationship between local cytokine production and lesional T-cell activities","volume":"143","author":"Sun","year":"2000","journal-title":"Br J Dermatol."},{"issue":"6","key":"10.1016\/j.autrev.2019.03.009_bb0610","doi-asserted-by":"crossref","first-page":"746","DOI":"10.5005\/jp-journals-10024-1610","article-title":"Evaluation of interleukin-1\u03b1, interleukin-10, tumor necrosis factor-\u03b1 and transforming growth factor-\u03b2 in the serum of patients with pemphigus vulgaris","volume":"15","author":"Khozeimeh","year":"2014","journal-title":"J Contemp Dent Pract."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0615","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1006\/clim.2001.5061","article-title":"Pemphigus vulgaris: the role of IL-1 and IL-1 receptor antagonist in pathogenesis and effects of intravenous immunoglobulin on their production","volume":"100","author":"Bhol","year":"2001","journal-title":"Clin Immunol."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0620","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.jdermsci.2008.10.012","article-title":"Increased CCL1 levels in the sera and blister fluid of patients with bullous pemphigoid","volume":"54","author":"Miyagaki","year":"2009","journal-title":"J Dermatol Sci."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0625","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.jdermsci.2016.04.009","article-title":"Increased expression of NLRP3 inflammasome components and interleukin-18 in patients with bullous pemphigoid","volume":"83","author":"Fang","year":"2016","journal-title":"J Dermatol Sci."},{"issue":"3","key":"10.1016\/j.autrev.2019.03.009_bb0630","first-page":"174","article-title":"The effect of conventional immunosuppressive therapy on cytokine serum levels in pemphigus vulgaris patients","volume":"13","author":"Mortazavi","year":"2014","journal-title":"Iran J Allergy Asthma Immunol."},{"key":"10.1016\/j.autrev.2019.03.009_bb0635","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/7151285","article-title":"Th1\/Th17-related cytokines and chemokines and their implications in the pathogenesis of Pemphigus Vulgaris","volume":"2017","author":"Timoteo","year":"2017","journal-title":"Mediators Inflamm."},{"key":"10.1016\/j.autrev.2019.03.009_bb0640","doi-asserted-by":"crossref","first-page":"978","DOI":"10.3389\/fimmu.2017.00978","article-title":"Cytokine and chemokines alterations in the endemic form of Pemphigus Foliaceus (Fogo Selvagem)","volume":"8","author":"Tim\u00f3teo","year":"2017","journal-title":"Front Immunol."},{"issue":"3","key":"10.1016\/j.autrev.2019.03.009_bb0645","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1111\/j.1365-2133.2006.07601.x","article-title":"Serum chemokine profile in patients with bullous pemphigoid","volume":"156","author":"Nakashima","year":"2007","journal-title":"Br J Dermatol."},{"issue":"7","key":"10.1016\/j.autrev.2019.03.009_bb0650","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1016\/j.jid.2017.03.019","article-title":"TWEAK\/Fn14 activation contributes to the pathogenesis of Bullous Pemphigoid","volume":"137","author":"Liu","year":"2017","journal-title":"J Invest Dermatol."},{"issue":"3","key":"10.1016\/j.autrev.2019.03.009_bb0655","first-page":"1223","article-title":"Cytokine Indexes in Pemphigus Vulgaris: perception of its immunpathogenesis and hopes for non-steroidal treatment","volume":"16","author":"Masjedi","year":"2017","journal-title":"Iran J Pharm Res."},{"issue":"6","key":"10.1016\/j.autrev.2019.03.009_bb0660","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1080\/08820130902943097","article-title":"Involvement of T(H)1\/T(H)2 cytokines in the pathogenesis of autoimmune skin disease-Pemphigus vulgaris","volume":"38","author":"Satyam","year":"2009","journal-title":"Immunol Invest."},{"issue":"4","key":"10.1016\/j.autrev.2019.03.009_bb0665","first-page":"383","article-title":"Cytokines in the sera of patients with pemphigus vulgaris: interleukin-6 and tumour necrosis factor-alpha levels are significantly increased as compared to healthy subjects and correlate with disease activity","volume":"8","author":"D'Auria","year":"1997","journal-title":"Eur Cytokine Netw."},{"issue":"3","key":"10.1016\/j.autrev.2019.03.009_bb0670","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1177\/039139889001300309","article-title":"Clinical and laboratory evaluation of hemocarboadsorption in autoimmune bullous dermatoses","volume":"13","author":"Grando","year":"1990","journal-title":"Int J Artif Organs."},{"issue":"9","key":"10.1016\/j.autrev.2019.03.009_bb0675","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1590\/S0100-879X2000000900012","article-title":"Serum cytokines in patients with Brazilian pemphigus foliaceus (fogo selvagem)","volume":"33","author":"Zeoti","year":"2000","journal-title":"Braz J Med Biol Res."},{"issue":"7","key":"10.1016\/j.autrev.2019.03.009_bb0680","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/BF02507102","article-title":"Detection of elevated levels of IL-4, IL-6, and IL-10 in blister fluid of bullous pemphigoid","volume":"288","author":"Schmidt","year":"1996","journal-title":"Arch Dermatol Res."},{"issue":"4","key":"10.1016\/j.autrev.2019.03.009_bb0685","doi-asserted-by":"crossref","first-page":"438","DOI":"10.5021\/ad.2017.29.4.438","article-title":"Analysis of serum cytokine profile in Pemphigus","volume":"29","author":"Lee","year":"2017","journal-title":"Ann Dermatol."},{"key":"10.1016\/j.autrev.2019.03.009_bb0690","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/936545","article-title":"Mediators of mast cells in bullous pemphigoid and dermatitis herpetiformis","volume":"2014","author":"Zebrowska","year":"2014","journal-title":"Mediators Inflamm."},{"issue":"3","key":"10.1016\/j.autrev.2019.03.009_bb0695","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1111\/j.1365-2249.2004.02570.x","article-title":"Interleukin-16 expression and release in bullous pemphigoid","volume":"137","author":"Frezzolini","year":"2004","journal-title":"Clin Exp Immunol."},{"issue":"12","key":"10.1016\/j.autrev.2019.03.009_bb0700","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1007\/s004030050259","article-title":"T-helper 2 involvement in the pathogenesis of bullous pemphigoid: role of soluble CD30 (sCD30)","volume":"289","author":"De Pit\u00e1","year":"1997","journal-title":"Arch Dermatol Res."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0705","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/imm.12814","article-title":"T helper type 1 polarizing \u03b3\u03b4 T cells and Scavenger receptors contribute to the pathogenesis of Pemphigus vulgaris","volume":"153","author":"Das","year":"2018","journal-title":"Immunology."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0710","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1159\/000018085","article-title":"Lack of expression of interleukin 8 and RANTES in autoimmune bullous skin diseases","volume":"198","author":"Bornscheuer","year":"1999","journal-title":"Dermatology."},{"issue":"5","key":"10.1016\/j.autrev.2019.03.009_bb0715","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1007\/BF00372588","article-title":"Increased immunoreactive interleukin-5 levels in blister fluids of bullous pemphigoid","volume":"284","author":"Endo","year":"1992","journal-title":"Arch Dermatol Res."},{"issue":"4","key":"10.1016\/j.autrev.2019.03.009_bb0720","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1080\/000155599750010689","article-title":"Blister fluid cytokines in cutaneous inflammatory bullous disorders","volume":"79","author":"Rhodes","year":"1999","journal-title":"Acta Derm Venereol."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0725","first-page":"11","article-title":"Increased serum IL-6, TNF-alpha and IL-10 levels in patients with bullous pemphigoid: relationships with disease activity","volume":"12","author":"D'Auria","year":"1999","journal-title":"J Eur Acad Dermatol Venereol."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0730","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1002\/path.5061","article-title":"Proinflammatory role of blister fluid-derived exosomes in bullous pemphigoid","volume":"245","author":"Fang","year":"2018","journal-title":"J Pathol."},{"key":"10.1016\/j.autrev.2019.03.009_bb0735","doi-asserted-by":"crossref","DOI":"10.1155\/2008\/875394","article-title":"Serum concentration of interleukin-6 is increased both in active and remission stages of pemphigus vulgaris","volume":"2008","author":"Narbutt","year":"2008","journal-title":"Mediators Inflamm."},{"issue":"4","key":"10.1016\/j.autrev.2019.03.009_bb0740","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1034\/j.1600-0714.2003.00096.x","article-title":"Levamisole and Chinese medicinal herbs can modulate the serum interleukin-6 level in patients with recurrent aphthous ulcerations","volume":"32","author":"Sun","year":"2003","journal-title":"J Oral Pathol Med."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0745","first-page":"121","article-title":"ICAM-1, ELAM-1, TNF-alpha and IL-6 in serum and blister liquid of pemphigus vulgaris patients","volume":"58","author":"Alecu","year":"1999","journal-title":"Roum Arch Microbiol Immunol."},{"issue":"3","key":"10.1016\/j.autrev.2019.03.009_bb0750","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1046\/j.1523-1747.1999.00520.x","article-title":"Elevated serum levels of interleukin-6 in paraneoplastic pemphigus","volume":"112","author":"Nousari","year":"1999","journal-title":"J Invest Dermatol."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0755","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0148919","article-title":"Increased frequency of T Follicular Helper Cells and Elevated Interleukin-27 plasma levels in patients with Pemphigus","volume":"11","author":"Hennerici","year":"2016","journal-title":"PLoS One."},{"issue":"3","key":"10.1016\/j.autrev.2019.03.009_bb0760","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.cyto.2007.12.007","article-title":"Cytokine profiles in pemphigus vulgaris patients treated with intravenous immunoglobulins as compared to conventional immunosuppressive therapy","volume":"41","author":"Keskin","year":"2008","journal-title":"Cytokine."},{"issue":"4","key":"10.1016\/j.autrev.2019.03.009_bb0765","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1111\/j.1600-0625.1998.tb00317.x","article-title":"Decreased interleukin-7 and transforming growth factor-beta1 levels in blister fluids as compared to the respective serum levels in patients with bullous pemphigoid. Opposite behavior of TNF-alpha, interleukin-4 and interleukin-10","volume":"7","author":"Giacalone","year":"1998","journal-title":"Exp Dermatol."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0770","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1111\/jdv.12091","article-title":"Regulatory T cells in skin lesions and blood of patients with bullous pemphigoid","volume":"28","author":"Antiga","year":"2014","journal-title":"J Eur Acad Dermatol Venereol."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0775","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1159\/000063895","article-title":"Cytokine pattern in blister fluid and sera of patients with pemphigus","volume":"205","author":"Baroni","year":"2002","journal-title":"Dermatology."},{"issue":"4","key":"10.1016\/j.autrev.2019.03.009_bb0780","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1111\/j.1365-2133.2008.08979.x","article-title":"CCL18 is expressed in patients with bullous pemphigoid and parallels disease course","volume":"160","author":"G\u00fcnther","year":"2009","journal-title":"Br J Dermatol."},{"issue":"10","key":"10.1016\/j.autrev.2019.03.009_bb0785","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1016\/j.imbio.2015.06.008","article-title":"Distinctive Treg associated CCR4-CCL22 expression profile with altered frequency of Th17\/Treg cell in the immunopathogenesis of Pemphigus Vulgaris","volume":"220","author":"Asothai","year":"2015","journal-title":"Immunobiology."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0790","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1038\/jid.2011.251","article-title":"High levels of CCL26 in blister fluid and sera of patients with bullous pemphigoid","volume":"132","author":"Kagami","year":"2012","journal-title":"J Invest Dermatol."},{"issue":"6","key":"10.1016\/j.autrev.2019.03.009_bb0795","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1007\/s004030050421","article-title":"Increased serum interleukin-15 levels in bullous skin diseases: correlation with disease intensity","volume":"291","author":"D'Auria","year":"1999","journal-title":"Arch Dermatol Res."},{"issue":"5","key":"10.1016\/j.autrev.2019.03.009_bb0800","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1111\/j.0022-202X.2005.23700.x","article-title":"Increased serum CCL28 levels in patients with atopic dermatitis, psoriasis vulgaris and bullous pemphigoid","volume":"124","author":"Kagami","year":"2005","journal-title":"J Invest Dermatol."},{"key":"10.1016\/j.autrev.2019.03.009_bb0805","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/967987","article-title":"IL-17 expression in dermatitis herpetiformis and bullous pemphigoid","volume":"2013","author":"Zebrowska","year":"2013","journal-title":"Mediators Inflamm."},{"key":"10.1016\/j.autrev.2019.03.009_bb0810","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/8980534","article-title":"Correlation between IL36\u03b1 and IL17 and activity of the disease in selected autoimmune blistering diseases","volume":"2017","author":"\u017bebrowska","year":"2017","journal-title":"Mediators Inflamm."},{"key":"10.1016\/j.autrev.2019.03.009_bb0815","doi-asserted-by":"crossref","DOI":"10.1038\/srep18001","article-title":"Integrating longitudinal serum IL-17 and IL-23 follow-up, along with autoantibodies variation, contributes to predict bullous pemphigoid outcome","volume":"5","author":"Pl\u00e9e","year":"2015","journal-title":"Sci Rep."},{"issue":"12","key":"10.1016\/j.autrev.2019.03.009_bb0820","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1111\/j.1600-0625.2011.01378.x","article-title":"Lesional Th17 cells and regulatory T cells in bullous pemphigoid","volume":"20","author":"Arakawa","year":"2011","journal-title":"Exp Dermatol."},{"key":"10.1016\/j.autrev.2019.03.009_bb0825","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1186\/1756-0500-7-536","article-title":"Vitamin D deficiency and lower TGF-\u03b2\/IL-17 ratio in a North Indian cohort of pemphigus vulgaris","volume":"7","author":"Joshi","year":"2014","journal-title":"BMC Res Notes."},{"issue":"7","key":"10.1016\/j.autrev.2019.03.009_bb0830","doi-asserted-by":"crossref","first-page":"e68145","DOI":"10.1371\/journal.pone.0068145","article-title":"Follicular helper T Cells (Tfh) and IL-21 involvement in the pathogenesis of bullous pemphigoid","volume":"8","author":"Li","year":"2013","journal-title":"PLoS One."},{"issue":"12","key":"10.1016\/j.autrev.2019.03.009_bb0835","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1111\/exd.13157","article-title":"A possible interaction between periostin and CD163","volume":"26","author":"Fujimura","year":"2017","journal-title":"Exp Dermatol."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0840","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/S0190-9622(96)80146-0","article-title":"Elevated levels of interleukin-8 in blister fluid of bullous pemphigoid compared with suction blisters of healthy control subjects","volume":"34","author":"Schmidt","year":"1996","journal-title":"J Am Acad Dermatol."},{"issue":"4","key":"10.1016\/j.autrev.2019.03.009_bb0845","first-page":"261","article-title":"Elevated levels of interleukin-23 in sera of patients with pemphigus vulgaris","volume":"9","author":"Pouralibaba","year":"2012","journal-title":"Iran J Immunol."},{"issue":"8","key":"10.1016\/j.autrev.2019.03.009_bb0850","doi-asserted-by":"crossref","first-page":"766","DOI":"10.2340\/00015555-2951","article-title":"Eosinophils are a major source of Interleukin-31 in Bullous Pemphigoid","volume":"98","author":"R\u00fcdrich","year":"2018","journal-title":"Acta Derm Venereol."},{"issue":"3","key":"10.1016\/j.autrev.2019.03.009_bb0855","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.jdermsci.2017.07.019","article-title":"Elevated IL-31 serum levels in bullous pemphigoid patients correlate with eosinophil numbers and are associated with BP180-IgE","volume":"87","author":"Salz","year":"2017","journal-title":"J Dermatol Sci."},{"key":"10.1016\/j.autrev.2019.03.009_bb0860","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/5965492","article-title":"The role of Intereukin-31 in pathogenesis of itch and its intensity in a course of Bullous Pemphigoid and Dermatitis Herpetiformis","volume":"2017","author":"Kulczycka-Siennicka","year":"2017","journal-title":"Biomed Res Int."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0865","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.jdermsci.2017.04.008","article-title":"Serum levels and tissue expression of interleukin-31 in dermatitis herpetiformis and bullous pemphigoid","volume":"87","author":"Bonciani","year":"2017","journal-title":"J Dermatol Sci."},{"issue":"3","key":"10.1016\/j.autrev.2019.03.009_bb0870","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1684\/ejd.2012.1706","article-title":"The levels of soluble ST2 in sera and bullous fluid from patients with bullous pemphigoid","volume":"22","author":"Wakatabi","year":"2012","journal-title":"Eur J Dermatol."},{"issue":"3","key":"10.1016\/j.autrev.2019.03.009_bb0875","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1111\/bjd.13716","article-title":"Elevated interleukin-33 and soluble ST2 levels in the sera of patients with pemphigus vulgaris: correlation with clinical and immunological parameters during follow-up","volume":"173","author":"Tirado-S\u00e1nchez","year":"2015","journal-title":"Br J Dermatol."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0880","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.jdermsci.2006.12.008","article-title":"Increased serum levels of a proliferation-inducing ligand in patients with bullous pemphigoid","volume":"46","author":"Watanabe","year":"2007","journal-title":"J Dermatol Sci."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0885","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1600-0625.2006.00485.x","article-title":"Elevated serum BAFF levels in patients with localized scleroderma in contrast to other organ-specific autoimmune diseases","volume":"16","author":"Matsushita","year":"2007","journal-title":"Exp Dermatol."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0890","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1111\/j.1365-2133.2006.07305.x","article-title":"Serum levels of BAFF are increased in bullous pemphigoid but not in pemphigus vulgaris","volume":"155","author":"Asashima","year":"2006","journal-title":"Br J Dermatol."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0895","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1159\/000247496","article-title":"Role of cell-mediated immune reaction in blister formation of bullous pemphigoid","volume":"184","author":"Kaneko","year":"1992","journal-title":"Dermatology."},{"issue":"7","key":"10.1016\/j.autrev.2019.03.009_bb0900","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0070496","article-title":"Aberrant expression and secretion of heat shock protein 90 in patients with bullous pemphigoid","volume":"8","author":"Tukaj","year":"2013","journal-title":"PLoS One."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0905","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1097\/00003072-198801000-00004","article-title":"Flare responses in small cell carcinoma of the lung","volume":"13","author":"Cosolo","year":"1988","journal-title":"Clin Nucl Med."},{"issue":"1","key":"10.1016\/j.autrev.2019.03.009_bb0910","first-page":"216","article-title":"Irritable bowel syndrome: is it rare in children?","volume":"27","author":"Rukunuzzaman","year":"2018","journal-title":"Mymensingh Med J."},{"issue":"2","key":"10.1016\/j.autrev.2019.03.009_bb0915","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1111\/jdv.13905","article-title":"Increased serum levels of vascular endothelial growth factor in pemphigus foliaceus patients with erythroderma","volume":"31","author":"Miyamoto","year":"2017","journal-title":"J Eur Acad Dermatol Venereol."}],"container-title":["Autoimmunity Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S156899721930062X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S156899721930062X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T21:15:26Z","timestamp":1761599726000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S156899721930062X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5]]},"references-count":183,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["S156899721930062X"],"URL":"https:\/\/doi.org\/10.1016\/j.autrev.2019.03.009","relation":{},"ISSN":["1568-9972"],"issn-type":[{"value":"1568-9972","type":"print"}],"subject":[],"published":{"date-parts":[[2019,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Serum and blister fluid levels of cytokines and chemokines in pemphigus and bullous pemphigoid","name":"articletitle","label":"Article Title"},{"value":"Autoimmunity Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.autrev.2019.03.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}