{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T18:25:43Z","timestamp":1792520743756,"version":"4.5.0"},"reference-count":96,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,6,9]],"date-time":"2022-06-09T00:00:00Z","timestamp":1654732800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Autoimmunity Reviews"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.autrev.2022.103131","type":"journal-article","created":{"date-parts":[[2022,6,9]],"date-time":"2022-06-09T17:11:45Z","timestamp":1654794705000},"page":"103131","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"title":["Aquaporins: Unexpected actors in autoimmune diseases"],"prefix":"10.1016","volume":"21","author":[{"given":"Christine","family":"Delporte","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Soyfoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.autrev.2022.103131_bb0005","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.autrev.2018.10.005","article-title":"Innate immune-responses and their role in driving autoimmunity","volume":"18","author":"Toubi","year":"2019","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.autrev.2022.103131_bb0010","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1007\/s10875-012-9815-8","article-title":"Autoimmunity: homeostasis of innate immunity gone awry","volume":"32","author":"Park","year":"2012","journal-title":"J Clin Immunol"},{"key":"10.1016\/j.autrev.2022.103131_bb0015","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1007\/s12016-017-8606-7","article-title":"Myeloid populations in systemic autoimmune diseases","volume":"53","author":"Morell","year":"2017","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.1016\/j.autrev.2022.103131_bb0020","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1684\/ecn.2020.0460","article-title":"Innate lymphoid cell subsets and their cytokines in autoimmune diseases","volume":"31","author":"Maleki","year":"2020","journal-title":"Eur Cytokine Netw"},{"key":"10.1016\/j.autrev.2022.103131_bb0025","doi-asserted-by":"crossref","first-page":"4278","DOI":"10.1002\/anie.200460804","article-title":"Aquaporin water channels (Nobel lecture)","volume":"43","author":"Agre","year":"2004","journal-title":"Angew Chem Int Ed Engl"},{"key":"10.1016\/j.autrev.2022.103131_bb0030","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1083\/jcb.123.3.605","article-title":"Tetrameric assembly of CHIP28 water channels in liposomes and cell membranes: a freeze-fracture study","volume":"123","author":"Verbavatz","year":"1993","journal-title":"J Cell Biol"},{"key":"10.1016\/j.autrev.2022.103131_bb0035","first-page":"F463","article-title":"Aquaporin CHIP: the archetypal molecular water channel","volume":"265","author":"Agre","year":"1993","journal-title":"Am J Physiol"},{"key":"10.1016\/j.autrev.2022.103131_bb0040","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1038\/nrd4226","article-title":"Aquaporins: important but elusive drug targets","volume":"13","author":"Verkman","year":"2014","journal-title":"Nat Rev Drug Discov"},{"key":"10.1016\/j.autrev.2022.103131_bb0045","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.4161\/cbt.9.12.11705","article-title":"Critical role of aquaporin-3 in the human epidermal growth factor-induced migration and proliferation in the human gastric adenocarcinoma cells","volume":"9","author":"Huang","year":"2010","journal-title":"Cancer Biol Ther"},{"key":"10.1016\/j.autrev.2022.103131_bb0050","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1007\/s00424-007-0357-5","article-title":"Aquaporins and cell migration","volume":"456","author":"Papadopoulos","year":"2008","journal-title":"Pflugers Arch"},{"key":"10.1016\/j.autrev.2022.103131_bb0055","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1189\/jlb.0910540","article-title":"Aquaporin 9 phosphorylation mediates membrane localization and neutrophil polarization","volume":"90","author":"Karlsson","year":"2011","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.autrev.2022.103131_bb0060","doi-asserted-by":"crossref","first-page":"11230","DOI":"10.1039\/C9RA00818G","article-title":"Properties of immature and mature dendritic cells: phenotype, morphology, phagocytosis, and migration","volume":"9","author":"Kim","year":"2019","journal-title":"RSC Adv"},{"key":"10.1016\/j.autrev.2022.103131_bb0065","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1146\/annurev-immunol-032712-095910","article-title":"Pathways of antigen processing","volume":"31","author":"Blum","year":"2013","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.autrev.2022.103131_bb0070","first-page":"429","article-title":"Antigen-presenting cells: potential of proven und new players in immune therapies","volume":"47","author":"Eiz-Vesper","year":"2020","journal-title":"TMH"},{"key":"10.1016\/j.autrev.2022.103131_bb0075","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1084\/jem.184.2.747","article-title":"Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation","volume":"184","author":"Cella","year":"1996","journal-title":"J Exp Med"},{"key":"10.1016\/j.autrev.2022.103131_bb0080","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1038\/nri3754","article-title":"Atypical MHC class II-expressing antigen-presenting cells: can anything replace a dendritic cell?","volume":"14","author":"Kambayashi","year":"2014","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.autrev.2022.103131_bb0085","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.3389\/fimmu.2017.01781","article-title":"Granulocytes: new members of the antigen-presenting cell family","volume":"8","author":"Lin","year":"2017","journal-title":"Front Immunol"},{"key":"10.1016\/j.autrev.2022.103131_bb0090","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s13223-018-0278-1","article-title":"An introduction to immunology and immunopathology","volume":"14","author":"Marshall","year":"2018","journal-title":"Allergy Asthma Clin Immunol"},{"key":"10.1016\/j.autrev.2022.103131_bb0095","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.molimm.2011.07.015","article-title":"Role of aquaporin 3 in development, subtypes and activation of dendritic cells","volume":"49","author":"Song","year":"2011","journal-title":"Mol Immunol"},{"key":"10.1016\/j.autrev.2022.103131_bb0100","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1002\/ajh.10476","article-title":"Aquaporin expression in human lymphocytes and dendritic cells","volume":"75","author":"Moon","year":"2004","journal-title":"Am J Hematol"},{"key":"10.1016\/j.autrev.2022.103131_bb0105","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1084\/jem.191.4.743","article-title":"The role of aquaporins in dendritic cell macropinocytosis","volume":"191","author":"de Baey","year":"2000","journal-title":"J Exp Med"},{"key":"10.1016\/j.autrev.2022.103131_bb0110","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1046\/j.1525-1470.2003.20501.x","article-title":"AQP1 and AQP3, psoriasin, and nitric oxide synthases 1\u20133 are inflammatory mediators in erythema toxicum neonatorum","volume":"20","author":"Marchini","year":"2003","journal-title":"Pediatr Dermatol"},{"key":"10.1016\/j.autrev.2022.103131_bb0115","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1096\/fj.11-186627","article-title":"Involvement of aquaporin-7 in the cutaneous primary immune response through modulation of antigen uptake and migration in dendritic cells","volume":"26","author":"Hara-Chikuma","year":"2012","journal-title":"FASEB J"},{"key":"10.1016\/j.autrev.2022.103131_bb0120","doi-asserted-by":"crossref","first-page":"2355","DOI":"10.3389\/fimmu.2018.02355","article-title":"Aquaporin 9 contributes to the maturation process and inflammatory cytokine secretion of murine dendritic cells","volume":"9","author":"De Santis","year":"2018","journal-title":"Front Immunol"},{"key":"10.1016\/j.autrev.2022.103131_bb0125","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1111\/j.1365-2249.2008.03702.x","article-title":"Membrane water permeability related to antigen-presenting function of dendritic cells","volume":"153","author":"Wang","year":"2008","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.autrev.2022.103131_bb0130","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1038\/mi.2014.65","article-title":"Classical versus alternative macrophage activation: the Ying and the Yang in host defense against pulmonary fungal infections","volume":"7","author":"Leopold Wager","year":"2014","journal-title":"Mucosal Immunol"},{"key":"10.1016\/j.autrev.2022.103131_bb0135","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/nri978","article-title":"Alternative activation of macrophages","volume":"3","author":"Gordon","year":"2003","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.autrev.2022.103131_bb0140","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1146\/annurev.immunol.021908.132532","article-title":"Alternative activation of macrophages: an immunologic functional perspective","volume":"27","author":"Martinez","year":"2009","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.autrev.2022.103131_bb0145","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0117398","article-title":"Regulation of macrophage motility by the water channel aquaporin-1: crucial role of M0\/M2 phenotype switch","volume":"10","author":"Tyteca","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.autrev.2022.103131_bb0150","doi-asserted-by":"crossref","first-page":"3073","DOI":"10.1007\/s00018-020-03708-3","article-title":"Aquaporin-3 is involved in NLRP3-inflammasome activation contributing to the setting of inflammatory response","volume":"78","author":"da Silva","year":"2021","journal-title":"Cell Mol Life Sci"},{"key":"10.1016\/j.autrev.2022.103131_bb0155","doi-asserted-by":"crossref","first-page":"2196","DOI":"10.1007\/s10753-018-0862-z","article-title":"Blockade of aquaporin 4 inhibits irradiation-induced pulmonary inflammation and modulates macrophage polarization in mice","volume":"41","author":"Li","year":"2018","journal-title":"Inflammation"},{"key":"10.1016\/j.autrev.2022.103131_bb0160","doi-asserted-by":"crossref","first-page":"4233","DOI":"10.1096\/fj.11-182808","article-title":"Defective macrophage function in aquaporin-3 deficiency","volume":"25","author":"Zhu","year":"2011","journal-title":"FASEB J"},{"key":"10.1016\/j.autrev.2022.103131_bb0165","doi-asserted-by":"crossref","first-page":"32","DOI":"10.3389\/fcimb.2016.00032","article-title":"Pseudomonas aeruginosa N-3-oxo-dodecanoyl-homoserine lactone elicits changes in cell volume, morphology, and AQP9 characteristics in macrophages","volume":"6","author":"Holm","year":"2016","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.autrev.2022.103131_bb0170","doi-asserted-by":"crossref","first-page":"915","DOI":"10.3389\/fmicb.2015.00915","article-title":"Pseudomonas aeruginosa lasI\/rhlI quorum sensing genes promote phagocytosis and aquaporin 9 redistribution to the leading and trailing regions in macrophages","volume":"6","author":"Holm","year":"2015","journal-title":"Front Microbiol"},{"key":"10.1016\/j.autrev.2022.103131_bb0175","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1007\/s00011-019-01285-1","article-title":"Aquaporin-1 attenuates macrophage-mediated inflammatory responses by inhibiting p38 mitogen-activated protein kinase activation in lipopolysaccharide-induced acute kidney injury","volume":"68","author":"Li","year":"2019","journal-title":"Inflamm Res"},{"key":"10.1016\/j.autrev.2022.103131_bb0180","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1007\/s00011-020-01334-0","article-title":"Aquaporin 1 alleviates acute kidney injury via PI3K-mediated macrophage M2 polarization","volume":"69","author":"Liu","year":"2020","journal-title":"Inflamm Res"},{"key":"10.1016\/j.autrev.2022.103131_bb0185","doi-asserted-by":"crossref","first-page":"5666","DOI":"10.1038\/s41467-020-19491-5","article-title":"Inhibition of aquaporin-3 in macrophages by a monoclonal antibody as potential therapy for liver injury","volume":"11","author":"Hara-Chikuma","year":"2020","journal-title":"Nat Commun"},{"key":"10.1016\/j.autrev.2022.103131_bb0190","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.immuni.2012.06.013","article-title":"Cell volume regulation modulates NLRP3 inflammasome activation","volume":"37","author":"Compan","year":"2012","journal-title":"Immunity"},{"key":"10.1016\/j.autrev.2022.103131_bb0195","doi-asserted-by":"crossref","first-page":"13937","DOI":"10.1074\/jbc.M113.534594","article-title":"Critical role of aquaporins in interleukin 1\u03b2 (IL-1\u03b2)-induced inflammation","volume":"289","author":"Rabolli","year":"2014","journal-title":"J Biol Chem"},{"key":"10.1016\/j.autrev.2022.103131_bb0200","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1189\/jlb.2AB0116-045R","article-title":"AQP8 transports NOX2-generated H2O2 across the plasma membrane to promote signaling in B cells","volume":"100","author":"Bertolotti","year":"2016","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.autrev.2022.103131_bb0205","doi-asserted-by":"crossref","first-page":"1743","DOI":"10.1084\/jem.20112398","article-title":"Chemokine-dependent T cell migration requires aquaporin-3-mediated hydrogen peroxide uptake","volume":"209","author":"Hara-Chikuma","year":"2012","journal-title":"J Exp Med"},{"key":"10.1016\/j.autrev.2022.103131_bb0210","doi-asserted-by":"crossref","first-page":"7417","DOI":"10.1038\/s41598-019-43884-2","article-title":"Aquaporin 4 inhibition alters chemokine receptor expression and T cell trafficking","volume":"9","author":"Nicosia","year":"2019","journal-title":"Sci Rep"},{"key":"10.1016\/j.autrev.2022.103131_bb0215","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1189\/jlb.71.2.212","article-title":"Neutrophil leukocyte motility requires directed water influx","volume":"71","author":"Loitto","year":"2002","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.autrev.2022.103131_bb0220","doi-asserted-by":"crossref","first-page":"15319","DOI":"10.1038\/srep15319","article-title":"Aquaporin-9-expressing neutrophils are required for the establishment of contact hypersensitivity","volume":"5","author":"Moniaga","year":"2015","journal-title":"Sci Rep"},{"key":"10.1016\/j.autrev.2022.103131_bb0225","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.bbrc.2016.01.153","article-title":"Aquaporin-9 facilitates membrane transport of hydrogen peroxide in mammalian cells","volume":"471","author":"Watanabe","year":"2016","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.autrev.2022.103131_bb0230","series-title":"Neuromyelitis optica (NMO, devics disease)","author":"Shumway","year":"2022"},{"key":"10.1016\/j.autrev.2022.103131_bb0235","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1111\/nyas.12794","article-title":"Neuromyelitis optica and the evolving spectrum of autoimmune aquaporin-4 channelopathies: a decade later","volume":"1366","author":"Pittock","year":"2016","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.autrev.2022.103131_bb0240","doi-asserted-by":"crossref","DOI":"10.1212\/NXI.0000000000000110","article-title":"Aquaporin-4 autoimmunity","volume":"2","author":"Zekeridou","year":"2015","journal-title":"Neurol Neuroimmunol Neuroinflamm"},{"key":"10.1016\/j.autrev.2022.103131_bb0245","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S1474-4422(12)70133-3","article-title":"Aquaporin 4 and neuromyelitis optica","volume":"11","author":"Papadopoulos","year":"2012","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.autrev.2022.103131_bb0250","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0074773","article-title":"Anti-aquaporin-1 autoantibodies in patients with neuromyelitis optica spectrum disorders","volume":"8","author":"Tzartos","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.autrev.2022.103131_bb0255","doi-asserted-by":"crossref","first-page":"E2299","DOI":"10.3390\/jcm9072299","article-title":"Current state of knowledge on primary Sj\u00f6gren\u2019s syndrome, an autoimmune exocrinopathy","volume":"9","author":"Parisis","year":"2020","journal-title":"J Clin Med"},{"key":"10.1016\/j.autrev.2022.103131_bb0260","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1007\/s12026-016-8786-x","article-title":"Detection of autoantibodies against aquaporin-5 in the sera of patients with primary Sj\u00f6gren\u2019s syndrome","volume":"64","author":"Alam","year":"2016","journal-title":"Immunol Res"},{"key":"10.1016\/j.autrev.2022.103131_bb0265","doi-asserted-by":"crossref","DOI":"10.3390\/jcm8111863","article-title":"Associations of anti-aquaporin 5 autoantibodies with serologic and histopathological features of Sj\u00f6gren\u2019s syndrome","volume":"8","author":"Jeon","year":"2019","journal-title":"J Clin Med"},{"key":"10.1016\/j.autrev.2022.103131_bb0270","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1177\/0022034517717965","article-title":"Functional epitopes for anti-aquaporin 5 antibodies in Sj\u00f6gren syndrome","volume":"96","author":"Alam","year":"2017","journal-title":"J Dent Res"},{"key":"10.1016\/j.autrev.2022.103131_bb0275","doi-asserted-by":"crossref","first-page":"103","DOI":"10.4110\/in.2017.17.2.103","article-title":"Detection of autoantibodies against aquaporin-1 in the sera of patients with primary Sj\u00f6gren\u2019s syndrome","volume":"17","author":"Alam","year":"2017","journal-title":"Immune Netw"},{"key":"10.1016\/j.autrev.2022.103131_bb0280","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1093\/rheumatology\/kex328","article-title":"Antibodies to aquaporins are frequent in patients with primary Sj\u00f6gren\u2019s syndrome","volume":"56","author":"Tzartos","year":"2017","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.autrev.2022.103131_bb0285","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.jaut.2012.07.008","article-title":"Astrocytic autoantibody of neuromyelitis optica (NMO-IgG) binds to aquaporin-4 extracellular loops, monomers, tetramers and high order arrays","volume":"40","author":"Iorio","year":"2013","journal-title":"J Autoimmun"},{"key":"10.1016\/j.autrev.2022.103131_bb0290","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1073\/pnas.1109980108","article-title":"Molecular outcomes of neuromyelitis optica (NMO)-IgG binding to aquaporin-4 in astrocytes","volume":"109","author":"Hinson","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.autrev.2022.103131_bb0295","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s12031-017-0905-1","article-title":"Aquaporin 4 forms a macromolecular complex with glutamate transporter 1 and Mu opioid receptor in astrocytes and participates in morphine dependence","volume":"62","author":"Wang","year":"2017","journal-title":"J Mol Neurosci"},{"key":"10.1016\/j.autrev.2022.103131_bb0300","doi-asserted-by":"crossref","first-page":"2473","DOI":"10.1084\/jem.20081241","article-title":"Aquaporin-4-binding autoantibodies in patients with neuromyelitis optica impair glutamate transport by down-regulating EAAT2","volume":"205","author":"Hinson","year":"2008","journal-title":"J Exp Med"},{"key":"10.1016\/j.autrev.2022.103131_bb0305","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1093\/brain\/awf151","article-title":"A role for humoral mechanisms in the pathogenesis of Devic\u2019s neuromyelitis optica","volume":"125","author":"Lucchinetti","year":"2002","journal-title":"Brain"},{"key":"10.1016\/j.autrev.2022.103131_bb0310","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2019.107827","article-title":"Affinity-matured \u201caquaporumab\u201d anti-aquaporin-4 antibody for therapy of seropositive neuromyelitis optica spectrum disorders","volume":"162","author":"Duan","year":"2020","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.autrev.2022.103131_bb0315","first-page":"1","article-title":"New progress in the treatment of neuromyelitis optica spectrum disorder with monoclonal antibodies (review)","volume":"21","author":"Xie","year":"2021","journal-title":"Exp Ther Med"},{"key":"10.1016\/j.autrev.2022.103131_bb0320","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1038\/labinvest.3780221","article-title":"Abnormal distribution of aquaporin-5 water channel protein in salivary glands from Sj\u00f6gren\u2019s syndrome patients","volume":"81","author":"Steinfeld","year":"2001","journal-title":"Lab Invest"},{"key":"10.1016\/j.autrev.2022.103131_bb0325","doi-asserted-by":"crossref","first-page":"384","DOI":"10.3109\/14397595.2015.1083146","article-title":"Abnormal distribution of AQP5 in labial salivary glands is associated with poor saliva secretion in patients with Sj\u00f6gren\u2019s syndrome including neuromyelitis optica complicated patients","volume":"26","author":"Yoshimura","year":"2016","journal-title":"Mod Rheumatol"},{"key":"10.1016\/j.autrev.2022.103131_bb0330","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1016\/S0140-6736(00)04140-4","article-title":"Defective cellular trafficking of lacrimal gland aquaporin-5 in Sj\u00f6gren\u2019s syndrome","volume":"357","author":"Tsubota","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.autrev.2022.103131_bb0335","doi-asserted-by":"crossref","first-page":"2566","DOI":"10.1002\/art.22826","article-title":"Modified aquaporin 5 expression and distribution in submandibular glands from NOD mice displaying autoimmune exocrinopathy","volume":"56","author":"Soyfoo","year":"2007","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.autrev.2022.103131_bb0340","first-page":"1071","article-title":"Abnormal distribution of aquaporin-5 in salivary glands in the NOD mouse model for Sj\u00f6gren\u2019s syndrome","volume":"32","author":"Konttinen","year":"2005","journal-title":"J Rheumatol"},{"key":"10.1016\/j.autrev.2022.103131_bb0345","article-title":"Autoantibodies against muscarinic type 3 receptor in Sj\u00f6gren\u2019s syndrome inhibit aquaporin 5 trafficking","volume":"8","author":"Lee","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.autrev.2022.103131_bb0350","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1080\/02713680802262819","article-title":"Altered distribution of aquaporin 5 and its C-terminal binding protein in the lacrimal glands of a mouse model for Sj\u00f6gren\u2019s syndrome","volume":"33","author":"Ohashi","year":"2008","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.autrev.2022.103131_bb0355","doi-asserted-by":"crossref","DOI":"10.3390\/cells10082108","article-title":"Unraveling human AQP5-PIP molecular interaction and effect on AQP5 salivary glands localization in SS patients","volume":"10","author":"Chivasso","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.autrev.2022.103131_bb0360","article-title":"Gross cystic disease fluid Protein-15(GCDFP-15)\/prolactin-inducible protein (PIP) as functional salivary biomarker for primary Sj\u00f6gren\u2019s syndrome","volume":"4","author":"Gallo","year":"2013","journal-title":"J Genet Syndr Gene Ther"},{"key":"10.1016\/j.autrev.2022.103131_bb0365","doi-asserted-by":"crossref","first-page":"9213","DOI":"10.3390\/ijms22179213","article-title":"Ezrin is a novel protein partner of aquaporin-5 in human salivary glands and shows altered expression and cellular localization in Sj\u00f6gren\u2019s syndrome","volume":"22","author":"Chivasso","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.autrev.2022.103131_bb0370","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1093\/rheumatology\/keq033","article-title":"Aberrant localization of ezrin correlates with salivary acini disorganization in Sjogren\u2019s syndrome","volume":"49","author":"P\u00e9rez","year":"2010","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.autrev.2022.103131_bb0375","doi-asserted-by":"crossref","first-page":"13505","DOI":"10.3390\/ijms222413505","article-title":"Ezrin regulates Ca2+ ionophore-induced plasma membrane translocation of aquaporin-5","volume":"22","author":"Muroi","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.autrev.2022.103131_bb0380","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1111\/j.1601-0825.2012.01909.x","article-title":"Link between inflammation and aquaporin-5 distribution in submandibular gland in Sj\u00f6gren\u2019s syndrome?","volume":"18","author":"Soyfoo","year":"2012","journal-title":"Oral Dis"},{"key":"10.1016\/j.autrev.2022.103131_bb0385","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1111\/j.1601-0825.2011.01902.x","article-title":"Relationship between aquaporin-5 expression and saliva flow in streptozotocin-induced diabetic mice?","volume":"18","author":"Soyfoo","year":"2012","journal-title":"Oral Dis"},{"key":"10.1016\/j.autrev.2022.103131_bb0390","doi-asserted-by":"crossref","first-page":"1766","DOI":"10.1111\/j.1582-4934.2011.01456.x","article-title":"TNF-\u03b1 inhibits aquaporin 5 expression in human salivary gland acinar cells via suppression of histone H4 acetylation","volume":"16","author":"Yamamura","year":"2012","journal-title":"J Cell Mol Med"},{"key":"10.1016\/j.autrev.2022.103131_bb0395","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1038\/labinvest.2016.141","article-title":"Pathogenic role of endogenous TNF-\u03b1 in the development of Sj\u00f6gren\u2019s-like sialadenitis and secretory dysfunction in non-obese diabetic mice","volume":"97","author":"Zhou","year":"2017","journal-title":"Lab Invest"},{"key":"10.1016\/j.autrev.2022.103131_bb0400","doi-asserted-by":"crossref","first-page":"39105","DOI":"10.1038\/srep39105","article-title":"Endogenous programmed death ligand-1 restrains the development and onset of Sj\u04e7gren\u2019s syndrome in non-obese diabetic mice","volume":"6","author":"Zhou","year":"2016","journal-title":"Sci Rep"},{"key":"10.1016\/j.autrev.2022.103131_bb0405","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/j.autrev.2010.05.008","article-title":"Functional role of M3 muscarinic acetylcholine receptor (M3R) reactive T cells and anti-M3R autoantibodies in patients with Sj\u00f6gren\u2019s syndrome","volume":"9","author":"Sumida","year":"2010","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.autrev.2022.103131_bb0410","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1002\/art.27362","article-title":"Disruption of tight junction structure in salivary glands from Sj\u00f6gren\u2019s syndrome patients is linked to proinflammatory cytokine exposure","volume":"62","author":"Ewert","year":"2010","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.autrev.2022.103131_bb0415","doi-asserted-by":"crossref","first-page":"5694","DOI":"10.1073\/pnas.1601992113","article-title":"Aquaporin gene therapy corrects Sj\u00f6gren\u2019s syndrome phenotype in mice","volume":"113","author":"Lai","year":"2016","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.autrev.2022.103131_bb0420","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1097\/01.LAB.0000038502.42845.9E","article-title":"Selective down-regulation of aquaporin-1 in salivary glands in primary Sj\u00f6gren\u2019s syndrome","volume":"82","author":"Beroukas","year":"2002","journal-title":"Lab Invest"},{"key":"10.1016\/j.autrev.2022.103131_bb0425","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1080\/08916934.2017.1341495","article-title":"Abnormal distribution of AQP4 in minor salivary glands of primary Sj\u00f6gren\u2019s syndrome patients","volume":"50","author":"Sisto","year":"2017","journal-title":"Autoimmunity"},{"key":"10.1016\/j.autrev.2022.103131_bb0430","doi-asserted-by":"crossref","DOI":"10.1042\/BSR20182303","article-title":"Physiological and pathological impact of AQP1 knockout in mice","volume":"39","author":"Hua","year":"2019","journal-title":"Biosci Rep"},{"key":"10.1016\/j.autrev.2022.103131_bb0435","doi-asserted-by":"crossref","first-page":"701","DOI":"10.2147\/JIR.S271664","article-title":"Overexpression of aquaporin 1 in synovium aggravates rat collagen-induced arthritis through regulating \u03b2-catenin signaling: an in vivo and in vitro study","volume":"13","author":"Mu","year":"2020","journal-title":"J Inflamm Res"},{"key":"10.1016\/j.autrev.2022.103131_bb0440","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.2147\/JIR.S312783","article-title":"Lentivirus-mediated overexpression or silencing of aquaporin 1 affects the proliferation, migration and invasion of TNF-\u03b1-stimulated rheumatoid arthritis fibroblast-like synoviocytes by Wnt\/\u03b2-catenin signaling pathway","volume":"14","author":"Zhou","year":"2021","journal-title":"J Inflamm Res"},{"key":"10.1016\/j.autrev.2022.103131_bb0445","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0006167","article-title":"AQP1 is not only a water channel: it contributes to cell migration through Lin7\/beta-catenin","volume":"4","author":"Monzani","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.autrev.2022.103131_bb0450","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1089\/scd.2013.0185","article-title":"Aqp1 enhances migration of bone marrow mesenchymal stem cells through regulation of FAK and \u03b2-catenin","volume":"23","author":"Meng","year":"2014","journal-title":"Stem Cells Dev"},{"key":"10.1016\/j.autrev.2022.103131_bb0455","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.700879","article-title":"Synovial fluid of patient with rheumatoid arthritis enhanced osmotic sensitivity through the cytotoxic edema module in synoviocytes","volume":"9","author":"Ji","year":"2021","journal-title":"Front Cell Dev Biol"},{"key":"10.1016\/j.autrev.2022.103131_bb0460","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1080\/13543776.2017.1236085","article-title":"Aquaporin modulators: a patent review (2010-2015)","volume":"27","author":"Soveral","year":"2017","journal-title":"Expert Opin Ther Pat"},{"key":"10.1016\/j.autrev.2022.103131_bb0465","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1093\/rheumatology\/keq028","article-title":"TNF-alpha-induced aquaporin 9 in synoviocytes from patients with OA and RA","volume":"49","author":"Nagahara","year":"2010","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.autrev.2022.103131_bb0470","first-page":"563","article-title":"Aquaporin-4 blockage by siRNA protects rat articular chondrocytes from IL-1\u03b2-induced apoptosis by inhibiting p38 MAPK signal pathway","volume":"47","author":"Cai","year":"2017","journal-title":"Ann Clin Lab Sci"},{"key":"10.1016\/j.autrev.2022.103131_bb0475","doi-asserted-by":"crossref","first-page":"19305","DOI":"10.1074\/jbc.M601728200","article-title":"Involvement of aquaporin 9 in osteoclast differentiation","volume":"281","author":"Aharon","year":"2006","journal-title":"J Biol Chem"},{"key":"10.1016\/j.autrev.2022.103131_bb0480","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1042\/BC20080083","article-title":"Osteoclast differentiation and function in aquaglyceroporin AQP9-null mice","volume":"101","author":"Liu","year":"2009","journal-title":"Biol Cell"}],"container-title":["Autoimmunity Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S156899722200101X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S156899722200101X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T21:28:15Z","timestamp":1761600495000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S156899722200101X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":96,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["S156899722200101X"],"URL":"https:\/\/doi.org\/10.1016\/j.autrev.2022.103131","relation":{},"ISSN":["1568-9972"],"issn-type":[{"value":"1568-9972","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Aquaporins: Unexpected actors in autoimmune diseases","name":"articletitle","label":"Article Title"},{"value":"Autoimmunity Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.autrev.2022.103131","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"103131"}}