{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T21:10:11Z","timestamp":1789161011991,"version":"build-2803163510"},"reference-count":77,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T00:00:00Z","timestamp":1749513600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81871224"],"award-info":[{"award-number":["81871224"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82371817"],"award-info":[{"award-number":["82371817"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Foundation of state key laboratory of pathogenesis, prvention and treatment of high incidence diseases in central asia","award":["SKL-HIDCA-2024-GD3"],"award-info":[{"award-number":["SKL-HIDCA-2024-GD3"]}]},{"DOI":"10.13039\/501100008233","name":"School of Medicine, Shanghai Jiao Tong University","doi-asserted-by":"publisher","award":["JYJC202408"],"award-info":[{"award-number":["JYJC202408"]}],"id":[{"id":"10.13039\/501100008233","id-type":"DOI","asserted-by":"publisher"}]},{"name":"The corss-over research fund program of The Ninth People's Hospital School of Medicine Shanghai Jiaotong University"},{"name":"Shanghai Songjiang District Research Project","award":["2024SJKJGG071"],"award-info":[{"award-number":["2024SJKJGG071"]}]},{"DOI":"10.13039\/501100015809","name":"Guangzhou Health Medical Collaborative Innovation Program","doi-asserted-by":"publisher","award":["2024CXJQ01"],"award-info":[{"award-number":["2024CXJQ01"]}],"id":[{"id":"10.13039\/501100015809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014718","name":"Innovative Research Group Project of the National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014718","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Autoimmunity Reviews"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.autrev.2025.103852","type":"journal-article","created":{"date-parts":[[2025,6,8]],"date-time":"2025-06-08T18:07:29Z","timestamp":1749406049000},"page":"103852","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["The role of B cells in Sj\u00f6gren's syndrome and their impact on the nervous system"],"prefix":"10.1016","volume":"24","author":[{"given":"Chuanxin","family":"Su","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Futao","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Song Guo","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.autrev.2025.103852_bb0005","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1016\/j.jds.2023.12.024","article-title":"Profiles of peripheral B cell subsets in a cohort of primary Sj\u00f6gren\u2019s syndrome patients and their potential clinical significance","volume":"19","author":"Xing","year":"2024","journal-title":"J. Dent. Sci."},{"issue":"6","key":"10.1016\/j.autrev.2025.103852_bb0010","doi-asserted-by":"crossref","first-page":"2987","DOI":"10.1007\/s00415-023-11613-5","article-title":"Sj\u00f6gren\u2019s syndrome with and without neurological involvement","volume":"270","author":"Seeliger","year":"2023","journal-title":"J. Neurol."},{"key":"10.1016\/j.autrev.2025.103852_bb0015","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.684999","article-title":"The multiple roles of B cells in the pathogenesis of Sj\u00f6gren\u2019s syndrome","volume":"12","author":"Du","year":"2021","journal-title":"Front. Immunol."},{"issue":"10","key":"10.1016\/j.autrev.2025.103852_bb0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2023.107943","article-title":"Single-cell transcriptome profiling reveals immune and stromal cell heterogeneity in primary Sj\u00f6gren\u2019s syndrome","volume":"26","author":"Xiang","year":"2023","journal-title":"iScience"},{"key":"10.1016\/j.autrev.2025.103852_bb0025","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.702505","article-title":"Autonomic nervous system dysfunction in primary Sj\u00f6gren\u2019s syndrome","volume":"12","author":"Davies","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.autrev.2025.103852_bb0030","article-title":"Lymphomagenesis predictors and related pathogenesis","volume":"4","author":"Ruiz-Ordo\u00f1ez","year":"2021","journal-title":"J. Transl. Autoimmun."},{"issue":"8","key":"10.1016\/j.autrev.2025.103852_bb0035","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1007\/s00296-020-04543-2","article-title":"Peripheral neuropathy and health-related quality of life in patients with primary Sj\u00f6gren\u2019s syndrome: a preliminary report","volume":"40","author":"Jask\u00f3lska","year":"2020","journal-title":"Rheumatol. Int."},{"issue":"3","key":"10.1016\/j.autrev.2025.103852_bb0040","first-page":"217","article-title":"B cell depletion with rituximab in the treatment of primary Sj\u00f6gren\u2019s syndrome: what have we learnt?","volume":"37 Suppl 118","author":"Grigoriadou","year":"2019","journal-title":"Clin. Exp. Rheumatol."},{"issue":"6","key":"10.1016\/j.autrev.2025.103852_bb0045","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1038\/s41591-024-03009-3","article-title":"CD40 ligand antagonist dazodalibep in Sj\u00f6gren\u2019s disease: a randomized, double-blinded, placebo-controlled, phase 2 trial","volume":"30","author":"St Clair","year":"2024","journal-title":"Nat. Med."},{"issue":"2","key":"10.1016\/j.autrev.2025.103852_bb0050","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1182\/blood-2011-03-341917","article-title":"Ex vivo characterization and isolation of rare memory B cells with antigen tetramers","volume":"118","author":"Franz","year":"2011","journal-title":"Blood"},{"issue":"3","key":"10.1016\/j.autrev.2025.103852_bb0055","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1038\/s41590-025-02102-0","article-title":"B cell immunometabolism in health and disease","volume":"26","author":"Martinis","year":"2025","journal-title":"Nat. Immunol."},{"issue":"2","key":"10.1016\/j.autrev.2025.103852_bb0060","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.cyto.2015.02.007","article-title":"B cells responses and cytokine production are regulated by their immune microenvironment","volume":"74","author":"Vazquez","year":"2015","journal-title":"Cytokine"},{"issue":"2","key":"10.1016\/j.autrev.2025.103852_bb0065","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0952-7915(97)80142-2","article-title":"B cell development and differentiation","volume":"9","author":"Burrows","year":"1997","journal-title":"Curr. Opin. Immunol."},{"issue":"21","key":"10.1016\/j.autrev.2025.103852_bb0070","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.183400","article-title":"BAFF promotes follicular helper T cell development and germinal center formation through BR3 signal","volume":"9","author":"Chen","year":"2024","journal-title":"JCI Insight"},{"issue":"3","key":"10.1016\/j.autrev.2025.103852_bb0075","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.cytogfr.2013.12.011","article-title":"The function of BAFF on T helper cells in autoimmunity","volume":"25","author":"Chen","year":"2014","journal-title":"Cytokine Growth Factor Rev."},{"issue":"8","key":"10.1016\/j.autrev.2025.103852_bb0080","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0023629","article-title":"BAFF promotes Th17 cells and aggravates experimental autoimmune encephalomyelitis","volume":"6","author":"Zhou","year":"2011","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.autrev.2025.103852_bb0085","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.trre.2018.07.002","article-title":"Advances in T follicular helper and T follicular regulatory cells in transplantation immunity","volume":"32","author":"Chen","year":"2018","journal-title":"Transplant. Rev. (Orlando)"},{"issue":"2","key":"10.1016\/j.autrev.2025.103852_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.autrev.2020.102743","article-title":"An updated advance of autoantibodies in autoimmune diseases","volume":"20","author":"Xiao","year":"2021","journal-title":"Autoimmun. Rev."},{"issue":"10","key":"10.1016\/j.autrev.2025.103852_bb0095","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1016\/j.ajt.2023.06.006","article-title":"Memory T follicular helper cells drive donor-specific antibodies independent of memory B cells and primary germinal center and alloantibody formation","volume":"23","author":"Zeng","year":"2023","journal-title":"Am. J. Transplant."},{"issue":"4","key":"10.1016\/j.autrev.2025.103852_bb0100","first-page":"2656","article-title":"CD31 promotes diffuse large B-cell lymphoma metastasis by upregulating OPN through the AKT pathway and inhibiting CD8+ T cells through the mTOR pathway","volume":"15","author":"He","year":"2023","journal-title":"Am. J. Transl. Res."},{"issue":"9","key":"10.1016\/j.autrev.2025.103852_bb0105","doi-asserted-by":"crossref","first-page":"4400","DOI":"10.4049\/jimmunol.1401720","article-title":"B cell-intrinsic TLR7 signaling is essential for the development of spontaneous germinal centers","volume":"193","author":"Soni","year":"2014","journal-title":"J. Immunol."},{"issue":"4","key":"10.1016\/j.autrev.2025.103852_bb0110","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.jaut.2009.11.001","article-title":"Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice","volume":"34","author":"Santiago-Raber","year":"2010","journal-title":"J. Autoimmun."},{"issue":"1","key":"10.1016\/j.autrev.2025.103852_bb0115","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.expneurol.2009.11.019","article-title":"Neurodegeneration in autoimmune CNS inflammation","volume":"225","author":"Herz","year":"2010","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.autrev.2025.103852_bb0120","first-page":"49","article-title":"Neurodegeneration in multiple sclerosis involves multiple pathogenic mechanisms","volume":"4","author":"Levin","year":"2014","journal-title":"Degener. Neurol. Neuromuscul. Dis."},{"key":"10.1016\/j.autrev.2025.103852_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2024.112077","article-title":"Roles of IRF4 in various immune cells in systemic lupus erythematosus","volume":"133","author":"Xiao","year":"2024","journal-title":"Int. Immunopharmacol."},{"issue":"2","key":"10.1016\/j.autrev.2025.103852_bb0130","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1002\/JLB.1MR0420-003RR","article-title":"The role of B7 family members in the generation of immunoglobulin","volume":"109","author":"Xiao","year":"2021","journal-title":"J. Leukoc. Biol."},{"issue":"12","key":"10.1016\/j.autrev.2025.103852_bb0135","first-page":"2668","article-title":"Regulatory T cells and B cells: implication on autoimmune diseases","volume":"6","author":"Wang","year":"2013","journal-title":"Int. J. Clin. Exp. Pathol."},{"issue":"1","key":"10.1016\/j.autrev.2025.103852_bb0140","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.cell.2018.05.059","article-title":"Size-dependent segregation controls macrophage phagocytosis of antibody-opsonized targets","volume":"174","author":"Bakalar","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.autrev.2025.103852_bb0145","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.876306","article-title":"Rapid Hypermutation B cell trajectory recruits previously primed B cells upon third SARS-Cov-2 mRNA vaccination","volume":"13","author":"Paschold","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.autrev.2025.103852_bb0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.clim.2024.109941","article-title":"Bruton\u2019s tyrosine kinase ablation inhibits B cell responses and antibody production for the prevention of chronic rejection in cardiac transplantation","volume":"261","author":"Han","year":"2024","journal-title":"Clin. Immunol."},{"issue":"2 Suppl 2","key":"10.1016\/j.autrev.2025.103852_bb0155","doi-asserted-by":"crossref","first-page":"S33","DOI":"10.1016\/j.jaci.2009.09.017","article-title":"Adaptive immunity","volume":"125","author":"Bonilla","year":"2010","journal-title":"J. Allergy Clin. Immunol."},{"issue":"1","key":"10.1016\/j.autrev.2025.103852_bb0160","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/s12865-023-00544-5","article-title":"Unsolved mystery of Fas: mononuclear cells may have trouble dying in patients with Sj\u00f6gren\u2019s syndrome","volume":"24","author":"Lindrova","year":"2023","journal-title":"BMC Immunol."},{"issue":"1","key":"10.1016\/j.autrev.2025.103852_bb0165","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.autrev.2006.03.003","article-title":"Immunohistopathology of Sj\u00f6gren\u2019s syndrome","volume":"6","author":"Konttinen","year":"2006","journal-title":"Autoimmun. Rev."},{"issue":"4","key":"10.1016\/j.autrev.2025.103852_bb0170","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.gpb.2015.06.002","article-title":"Biomarkers for Primary Sj\u00f6gren\u2019s Syndrome","volume":"13","author":"Chen","year":"2015","journal-title":"Genom. Proteom. Bioinform."},{"issue":"6","key":"10.1016\/j.autrev.2025.103852_bb0175","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.1093\/rheumatology\/key332","article-title":"B cells in Sj\u00f6gren\u2019s syndrome: from pathophysiology to therapeutic target","volume":"60","author":"Mielle","year":"2021","journal-title":"Rheumatology (Oxford)"},{"issue":"1","key":"10.1016\/j.autrev.2025.103852_bb0180","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.jdsr.2019.09.006","article-title":"B cell dysregulation in primary Sj\u00f6gren\u2019s syndrome: a review","volume":"55","author":"Ibrahem","year":"2019","journal-title":"Jpn. Dent. Sci. Rev."},{"issue":"1","key":"10.1016\/j.autrev.2025.103852_bb0185","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1093\/jleuko\/qiad049","article-title":"The role of epithelial cells in the immunopathogenesis of Sj\u00f6gren\u2019s syndrome","volume":"115","author":"Tang","year":"2024","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.autrev.2025.103852_bb0190","doi-asserted-by":"crossref","DOI":"10.1016\/j.smim.2021.101547","article-title":"Cellular and molecular diversity in Sjogren\u2019s syndrome salivary glands: towards a better definition of disease subsets","volume":"58","author":"Pontarini","year":"2021","journal-title":"Semin. Immunol."},{"key":"10.1016\/j.autrev.2025.103852_bb0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.clim.2025.110458","article-title":"Plasma extracellular vesicles promote follicular T helper cell expansion in primary Sj\u00f6gren\u2019s syndrome","volume":"273","author":"Liu","year":"2025","journal-title":"Clin. Immunol."},{"issue":"2","key":"10.1016\/j.autrev.2025.103852_bb0200","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1002\/JLB.5MR1020-057RR","article-title":"Follicular helper T cells and follicular regulatory T cells in the immunopathology of primary Sj\u00f6gren\u2019s syndrome","volume":"109","author":"Chen","year":"2021","journal-title":"J. Leukoc. Biol."},{"issue":"511","key":"10.1016\/j.autrev.2025.103852_bb0205","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aaw9414","article-title":"CAR T cells targeting BAFF-R can overcome CD19 antigen loss in B cell malignancies","volume":"11","author":"Qin","year":"2019","journal-title":"Sci. Transl. Med."},{"issue":"5","key":"10.1016\/j.autrev.2025.103852_bb0210","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1007\/s12026-023-09390-4","article-title":"Extracellular vesicle-encapsulated miR-10a-5p derived from MDSCs restrains germinal center B cells in experimental Sj\u00f6gren\u2019s syndrome","volume":"71","author":"Zhou","year":"2023","journal-title":"Immunol. Res."},{"issue":"5","key":"10.1016\/j.autrev.2025.103852_bb0215","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1136\/annrheumdis-2018-214720","article-title":"Treatment of primary Sj\u00f6gren\u2019s syndrome with ianalumab (VAY736) targeting B cells by BAFF receptor blockade coupled with enhanced, antibody-dependent cellular cytotoxicity","volume":"78","author":"D\u00f6rner","year":"2019","journal-title":"Ann. Rheum. Dis."},{"issue":"2","key":"10.1016\/j.autrev.2025.103852_bb0220","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1080\/03009742.2020.1809701","article-title":"Efficacy and safety of iguratimod on patients with primary Sj\u00f6gren\u2019s syndrome: a randomized, placebo-controlled clinical trial","volume":"50","author":"Shao","year":"2021","journal-title":"Scand. J. Rheumatol."},{"issue":"9","key":"10.1016\/j.autrev.2025.103852_bb0225","doi-asserted-by":"crossref","first-page":"3631","DOI":"10.4049\/jimmunol.1501740","article-title":"TGF-\u03b2-induced regulatory T cells directly suppress B cell responses through a noncytotoxic mechanism","volume":"196","author":"Xu","year":"2016","journal-title":"J. Immunol."},{"key":"10.1016\/j.autrev.2025.103852_bb0230","doi-asserted-by":"crossref","first-page":"35","DOI":"10.3389\/fimmu.2018.00035","article-title":"TGF-\u03b2-induced CD8(+)CD103(+) regulatory T cells show potent therapeutic effect on chronic graft-versus-host disease lupus by suppressing B cells","volume":"9","author":"Zhong","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.autrev.2025.103852_bb0235","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.3389\/fimmu.2017.01334","article-title":"In vivo attenuation of antibody-mediated acute renal allograft rejection by ex vivo TGF-\u03b2-induced CD4(+)Foxp3(+) regulatory T cells","volume":"8","author":"Liao","year":"2017","journal-title":"Front. Immunol."},{"issue":"8","key":"10.1016\/j.autrev.2025.103852_bb0240","doi-asserted-by":"crossref","first-page":"3878","DOI":"10.4049\/jimmunol.1201029","article-title":"Dendritic cell-specific disruption of TGF-\u03b2 receptor II leads to altered regulatory T cell phenotype and spontaneous multiorgan autoimmunity","volume":"189","author":"Ramalingam","year":"2012","journal-title":"J. Immunol."},{"issue":"12","key":"10.1016\/j.autrev.2025.103852_bb0245","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1038\/s41583-019-0233-2","article-title":"B cells in autoimmune and neurodegenerative central nervous system diseases","volume":"20","author":"Sabatino","year":"2019","journal-title":"Nat. Rev. Neurosci."},{"issue":"17","key":"10.1016\/j.autrev.2025.103852_bb0250","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23179851","article-title":"Unilateral cervical Vagotomy modulates immune cell profiles and the response to a traumatic brain injury","volume":"23","author":"Newell-Rogers","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"10","key":"10.1016\/j.autrev.2025.103852_bb0255","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1096\/fj.01-0467fje","article-title":"Autoreactive T cells induce neurotrophin production by immune and neural cells in injured rat optic nerve: implications for protective autoimmunity","volume":"16","author":"Barouch","year":"2002","journal-title":"FASEB J."},{"key":"10.1016\/j.autrev.2025.103852_bb0260","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.3389\/fnins.2019.01178","article-title":"Brain-immune interactions and Neuroinflammation after traumatic brain injury","volume":"13","author":"Dinet","year":"2019","journal-title":"Front. Neurosci."},{"issue":"7","key":"10.1016\/j.autrev.2025.103852_bb0265","doi-asserted-by":"crossref","DOI":"10.3390\/cells10071605","article-title":"B cells in Neuroinflammation: new perspectives and mechanistic insights","volume":"10","author":"Ahn","year":"2021","journal-title":"Cells"},{"issue":"12","key":"10.1016\/j.autrev.2025.103852_bb0270","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1038\/s12276-021-00714-8","article-title":"Single-cell RNA sequencing reveals B cell-related molecular biomarkers for Alzheimer\u2019s disease","volume":"53","author":"Xiong","year":"2021","journal-title":"Exp. Mol. Med."},{"issue":"3","key":"10.1016\/j.autrev.2025.103852_bb0275","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1111\/imm.13395","article-title":"Ectopic lymphoid follicles in progressive multiple sclerosis: from patients to animal models","volume":"164","author":"Zhan","year":"2021","journal-title":"Immunology"},{"issue":"6","key":"10.1016\/j.autrev.2025.103852_bb0280","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1111\/bpa.12583","article-title":"Dominant role of microglial and macrophage innate immune responses in human ischemic infarcts","volume":"28","author":"Zrzavy","year":"2018","journal-title":"Brain Pathol."},{"issue":"1","key":"10.1016\/j.autrev.2025.103852_bb0285","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/0303-8467(95)00014-B","article-title":"Autoimmune mechanisms in the pathogenesis of paraneoplastic nervous system disease","volume":"97","author":"Jaeckle","year":"1995","journal-title":"Clin. Neurol. Neurosurg."},{"key":"10.1016\/j.autrev.2025.103852_bb0290","article-title":"Quantification of autoreactive antibodies in mice upon experimental autoimmune encephalomyelitis","volume":"202","author":"Carver","year":"2023","journal-title":"J. Vis. Exp."},{"issue":"1","key":"10.1016\/j.autrev.2025.103852_bb0295","doi-asserted-by":"crossref","first-page":"8914","DOI":"10.1038\/s41467-024-53269-3","article-title":"Sensory neurons regulate stimulus-dependent humoral immunity in mouse models of bacterial infection and asthma","volume":"15","author":"Aguilar","year":"2024","journal-title":"Nat. Commun."},{"issue":"3","key":"10.1016\/j.autrev.2025.103852_bb0300","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/s00281-016-0615-8","article-title":"Potential importance of B cells in aging and aging-associated neurodegenerative diseases","volume":"39","author":"Biragyn","year":"2017","journal-title":"Semin. Immunopathol."},{"key":"10.1016\/j.autrev.2025.103852_bb0305","doi-asserted-by":"crossref","DOI":"10.1016\/j.jneuroim.2019.577106","article-title":"B cell function impacts the efficacy of IFN-\u03b2 therapy in EAE","volume":"338","author":"Agasing","year":"2020","journal-title":"J. Neuroimmunol."},{"issue":"1","key":"10.1016\/j.autrev.2025.103852_bb0310","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1002\/eji.200737557","article-title":"Levels of autoantibodies, unlike antibodies to all extrinsic antigen groups, fall following B cell depletion with rituximab","volume":"38","author":"Ferraro","year":"2008","journal-title":"Eur. J. Immunol."},{"issue":"1","key":"10.1016\/j.autrev.2025.103852_bb0315","first-page":"81","article-title":"Potent high-avidity neutralizing antibodies and T cell responses after COVID-19 vaccination in individuals with B cell lymphoma and multiple myeloma","volume":"4","author":"Keppler-Hafkemeyer","year":"2023","journal-title":"Nat. Can."},{"issue":"1","key":"10.1016\/j.autrev.2025.103852_bb0320","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1111\/imr.12810","article-title":"BAFF inhibition in SLE-is tolerance restored?","volume":"292","author":"Jackson","year":"2019","journal-title":"Immunol. Rev."},{"issue":"11","key":"10.1016\/j.autrev.2025.103852_bb0325","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1136\/ard-2024-225727","article-title":"B-cell depletion in autoimmune diseases","volume":"83","author":"Schett","year":"2024","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.autrev.2025.103852_bb0330","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2020.102418","article-title":"Correction of autophagy impairment inhibits pathology in the NOD.H-2h4 mouse model of primary Sj\u00f6gren\u2019s syndrome","volume":"108","author":"Voynova","year":"2020","journal-title":"J. Autoimmun."},{"issue":"5","key":"10.1016\/j.autrev.2025.103852_bb0335","doi-asserted-by":"crossref","DOI":"10.3390\/molecules28052400","article-title":"Bruton\u2019s tyrosine kinase inhibitors (BTKIs): review of preclinical studies and evaluation of clinical trials","volume":"28","author":"Rozkiewicz","year":"2023","journal-title":"Molecules"},{"issue":"4","key":"10.1016\/j.autrev.2025.103852_bb0340","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1007\/s10067-024-06901-y","article-title":"Identification and verification of inflammatory biomarkers for primary Sj\u00f6gren\u2019s syndrome","volume":"43","author":"Liu","year":"2024","journal-title":"Clin. Rheumatol."},{"issue":"23","key":"10.1016\/j.autrev.2025.103852_bb0345","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.163030","article-title":"A randomized, phase II study of sequential belimumab and rituximab in primary Sj\u00f6gren\u2019s syndrome","volume":"7","author":"Mariette","year":"2022","journal-title":"JCI Insight"},{"issue":"6","key":"10.1016\/j.autrev.2025.103852_bb0350","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1007\/s40259-021-00505-7","article-title":"Targeted therapy for primary Sj\u00f6gren\u2019s syndrome: where are we now?","volume":"35","author":"Wang","year":"2021","journal-title":"BioDrugs"},{"key":"10.1016\/j.autrev.2025.103852_bb0355","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1298815","article-title":"Concurrent remission of lymphoma and Sj\u00f6gren\u2019s disease following anti-CD19 chimeric antigen receptor-T cell therapy for diffuse large B-cell lymphoma: a case report","volume":"14","author":"Sheng","year":"2023","journal-title":"Front. Immunol."},{"key":"10.1016\/j.autrev.2025.103852_bb0360","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2024.107524","article-title":"Therapeutic potential of interleukin-17 neutralization in a novel humanized mouse model of Sj\u00f6gren\u2019s disease","volume":"210","author":"Yu","year":"2024","journal-title":"Pharmacol. Res."},{"issue":"2","key":"10.1016\/j.autrev.2025.103852_bb0365","doi-asserted-by":"crossref","DOI":"10.1212\/NXI.0000000000200080","article-title":"CAR-T cell-mediated B-cell depletion in central nervous system autoimmunity","volume":"10","author":"Gupta","year":"2023","journal-title":"Neurol. Neuroimmunol. Neuroinflamm."},{"issue":"4","key":"10.1016\/j.autrev.2025.103852_bb0370","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1586\/1744666X.2014.878650","article-title":"Dendritic cells, T-cells and epithelial cells: a crucial interplay in immunopathology of primary Sj\u00f6gren\u2019s syndrome","volume":"10","author":"Hillen","year":"2014","journal-title":"Expert Rev. Clin. Immunol."},{"issue":"766","key":"10.1016\/j.autrev.2025.103852_bb0375","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.adj1277","article-title":"B cells drive neuropathic pain-related behaviors in mice through IgG-Fc gamma receptor signaling","volume":"16","author":"Lacagnina","year":"2024","journal-title":"Sci. Transl. Med."},{"issue":"12","key":"10.1016\/j.autrev.2025.103852_bb0380","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1007\/s10067-013-2344-x","article-title":"High-dose methylprednisolone pulse therapy upregulated Fc\u03b3RIIb expression on B cells in primary Sj\u00f6gren\u2019s syndrome patients with thrombocytopenia","volume":"32","author":"Chen","year":"2013","journal-title":"Clin. Rheumatol."},{"issue":"179","key":"10.1016\/j.autrev.2025.103852_bb0385","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.24976\/Discov.Med.202335179.100","article-title":"Rapamycin plays an anti-epileptic role by restoring blood-brain barrier dysfunction, balancing T cell subsets and inhibiting neuronal apoptosis","volume":"35","author":"Xie","year":"2023","journal-title":"Discov. Med."}],"container-title":["Autoimmunity Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568997225001120?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568997225001120?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T22:06:24Z","timestamp":1762553184000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1568997225001120"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":77,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["S1568997225001120"],"URL":"https:\/\/doi.org\/10.1016\/j.autrev.2025.103852","relation":{},"ISSN":["1568-9972"],"issn-type":[{"value":"1568-9972","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The role of B cells in Sj\u00f6gren's syndrome and their impact on the nervous system","name":"articletitle","label":"Article Title"},{"value":"Autoimmunity Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.autrev.2025.103852","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"103852"}}