{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T00:31:25Z","timestamp":1793838685806,"version":"4.6.1"},"reference-count":139,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T00:00:00Z","timestamp":1753747200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Autoimmunity Reviews"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.autrev.2025.103896","type":"journal-article","created":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T15:44:59Z","timestamp":1753803899000},"page":"103896","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"title":["Specialized pro-resolving mediators and autoimmunity: Recent insights and future perspectives"],"prefix":"10.1016","volume":"24","author":[{"given":"Marta","family":"Vomero","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ludovica","family":"Lamberti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"Corberi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damiano","family":"Currado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annalisa","family":"Marino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Onorina","family":"Berardicurti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Fava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Leuti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"Maccarrone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Giacomelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Navarini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.autrev.2025.103896_bb0005","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/nature13479","article-title":"Pro-resolving lipid mediators are leads for resolution physiology","volume":"510","author":"Serhan","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.autrev.2025.103896_bb0010","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1038\/ni1276","article-title":"Resolution of inflammation: the beginning programs the end","volume":"6","author":"Serhan","year":"2005","journal-title":"Nat Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0015","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1038\/89759","article-title":"Lipid mediator class switching during acute inflammation: signals in resolution","volume":"2","author":"Levy","year":"2001","journal-title":"Nat Immunol"},{"issue":"Pt 17","key":"10.1016\/j.autrev.2025.103896_bb0020","first-page":"4037","article-title":"Resolvin D1 stimulates efferocytosis through p50\/p50-mediated suppression of tumor necrosis factor-\u03b1 expression","volume":"126","author":"Lee","year":"2013","journal-title":"J Cell Sci"},{"key":"10.1016\/j.autrev.2025.103896_bb0025","doi-asserted-by":"crossref","first-page":"5922","DOI":"10.1021\/cr100396c","article-title":"Resolvins and protectins in inflammation resolution","volume":"111","author":"Serhan","year":"2011","journal-title":"Chem Rev"},{"key":"10.1016\/j.autrev.2025.103896_bb0030","article-title":"Specific activity of mouse liver desaturases and elongases: Time course effects using n-3 and n-6 PUFA substrates and inhibitory responses of delta-6 desaturase","volume":"1870","author":"Valenzuela","year":"2025","journal-title":"Biochim Biophys Acta Mol Cell Biol Lipids"},{"key":"10.1016\/j.autrev.2025.103896_bb0035","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1002\/biof.1992","article-title":"Protein concentrations and activities of fatty acid desaturase and elongase enzymes in liver, brain, testicle, and kidney from mice: Substrate dependency","volume":"50","author":"Valenzuela","year":"2024","journal-title":"Biofactors"},{"key":"10.1016\/j.autrev.2025.103896_bb0040","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1038\/nri.2015.4","article-title":"Specialized pro-resolving mediators: endogenous regulators of infection and inflammation","volume":"16","author":"Basil","year":"2016","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0045","doi-asserted-by":"crossref","first-page":"181","DOI":"10.2147\/JIR.S90380","article-title":"Lipoxins: nature&#39;s way to resolve inflammation","author":"Sharma-walia","year":"2015","journal-title":"JIR"},{"key":"10.1016\/j.autrev.2025.103896_bb0050","doi-asserted-by":"crossref","first-page":"13266","DOI":"10.1073\/pnas.202296999","article-title":"Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 inhibit peroxynitrite formation, NF-kappa B and AP-1 activation, and IL-8 gene expression in human leukocytes","volume":"99","author":"J\u00f3zsef","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.autrev.2025.103896_bb0055","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1038\/cdd.2009.220","article-title":"Lipoxin A4 impairment of apoptotic signaling in macrophages: implication of the PI3K\/Akt and the ERK\/Nrf-2 defense pathways","volume":"17","author":"Prieto","year":"2010","journal-title":"Cell Death Differ"},{"key":"10.1016\/j.autrev.2025.103896_bb0060","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1146\/annurev.pathmechdis.3.121806.151409","article-title":"Anti-inflammatory and proresolving lipid mediators","volume":"3","author":"Serhan","year":"2008","journal-title":"Annu Rev Pathol"},{"key":"10.1016\/j.autrev.2025.103896_bb0065","doi-asserted-by":"crossref","first-page":"13794","DOI":"10.1096\/fj.201902003R","article-title":"Biosynthetic metabolomes of cysteinyl-containing immunoresolvents","volume":"33","author":"Jouvene","year":"2019","journal-title":"FASEB J"},{"key":"10.1016\/j.autrev.2025.103896_bb0070","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1038\/s41569-023-00984-x","article-title":"Specialized pro-resolving mediators in vascular inflammation and atherosclerotic cardiovascular disease","volume":"21","author":"Fredman","year":"2024","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.autrev.2025.103896_bb0075","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1172\/JCI114503","article-title":"Lipoxin formation during human neutrophil-platelet interactions. Evidence for the transformation of leukotriene A4 by platelet 12-lipoxygenase in vitro","volume":"85","author":"Serhan","year":"1990","journal-title":"J Clin Invest"},{"key":"10.1016\/j.autrev.2025.103896_bb0080","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1038\/ki.1995.184","article-title":"Transcellular biosynthesis of lipoxin A4 during adhesion of platelets and neutrophils in experimental immune complex glomerulonephritis","volume":"47","author":"Papayianni","year":"1995","journal-title":"Kidney Int"},{"key":"10.1016\/j.autrev.2025.103896_bb0085","doi-asserted-by":"crossref","first-page":"e60","DOI":"10.1182\/blood-2012-04-423525","article-title":"Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediators","volume":"120","author":"Dalli","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.autrev.2025.103896_bb0090","first-page":"397","article-title":"Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome","volume":"1851","author":"Serhan","year":"2015","journal-title":"Biochim Biophys Acta (BBA) Mol Cell Biol Lipids"},{"key":"10.1016\/j.autrev.2025.103896_bb0095","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1002\/ana.23928","article-title":"Neuroprotectin\/protectin D1 protects against neuropathic pain in mice after nerve trauma: NPD1\/PD1 and Neuropathic Pain","volume":"74","author":"Xu","year":"2013","journal-title":"Ann Neurol"},{"key":"10.1016\/j.autrev.2025.103896_bb0100","doi-asserted-by":"crossref","first-page":"14677","DOI":"10.1074\/jbc.M300218200","article-title":"Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation","volume":"278","author":"Hong","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1016\/j.autrev.2025.103896_bb0105","doi-asserted-by":"crossref","first-page":"3568","DOI":"10.1172\/JCI99888","article-title":"GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain","volume":"128","author":"Bang","year":"2018","journal-title":"J Clin Invest"},{"key":"10.1016\/j.autrev.2025.103896_bb0110","article-title":"First total syntheses of the pro-resolving lipid mediators 7(S),13(R),20(S)-Resolvin T1 and 7(S),13(R)-Resolvin T4","volume":"61","author":"Rodriguez","year":"2020","journal-title":"Tetrahedron Lett"},{"key":"10.1016\/j.autrev.2025.103896_bb0115","doi-asserted-by":"crossref","first-page":"11731","DOI":"10.1523\/JNEUROSCI.1395-17.2017","article-title":"Maresin 1 promotes inflammatory resolution, Neuroprotection, and functional neurological recovery after spinal cord injury","volume":"37","author":"Francos-Quijorna","year":"2017","journal-title":"J Neurosci"},{"key":"10.1016\/j.autrev.2025.103896_bb0120","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.bja.2018.10.062","article-title":"Maresin 1 attenuates neuroinflammation in a mouse model of perioperative neurocognitive disorders","volume":"122","author":"Yang","year":"2019","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.autrev.2025.103896_bb0125","doi-asserted-by":"crossref","first-page":"5294","DOI":"10.1172\/JCI129448","article-title":"Maresin 1 activates LGR6 receptor promoting phagocyte immunoresolvent functions","volume":"129","author":"Chiang","year":"2019","journal-title":"J Clin Invest"},{"key":"10.1016\/j.autrev.2025.103896_bb0130","doi-asserted-by":"crossref","first-page":"7628","DOI":"10.3390\/ijms21207628","article-title":"The role of resolvins: EPA and DHA derivatives can be useful in the prevention and treatment of ischemic stroke","volume":"21","author":"Tu\u0142owiecka","year":"2020","journal-title":"IJMS"},{"key":"10.1016\/j.autrev.2025.103896_bb0135","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.201900924","article-title":"Hormonal dysregulation and unbalanced specialized pro-resolving mediator biosynthesis contribute toward impaired B cell outcomes in obesity","volume":"65","author":"Crouch","year":"2021","journal-title":"Mol Nutr Food Res"},{"key":"10.1016\/j.autrev.2025.103896_bb0140","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1038\/nature11042","article-title":"Infection regulates pro-resolving mediators that lower antibiotic requirements","volume":"484","author":"Chiang","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.autrev.2025.103896_bb0145","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1111\/cei.13184","article-title":"Porphyromonas gingivalis in the tongue biofilm is associated with clinical outcome in rheumatoid arthritis patients","volume":"194","author":"Ceccarelli","year":"2018","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0150","doi-asserted-by":"crossref","first-page":"6856","DOI":"10.4049\/jimmunol.171.12.6856","article-title":"Reduced inflammation and tissue damage in transgenic rabbits overexpressing 15-Lipoxygenase and endogenous anti-inflammatory lipid mediators","volume":"171","author":"Serhan","year":"2003","journal-title":"J Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0155","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0024422","article-title":"Impaired phagocytosis in localized aggressive periodontitis: rescue by Resolvin E1","volume":"6","author":"Fredman","year":"2011","journal-title":"PloS One"},{"key":"10.1016\/j.autrev.2025.103896_bb0160","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1164\/rccm.200810-1601OC","article-title":"15-epi-lipoxin A4 inhibits myeloperoxidase signaling and enhances resolution of acute lung injury","volume":"180","author":"El Kebir","year":"2009","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.autrev.2025.103896_bb0165","doi-asserted-by":"crossref","first-page":"14983","DOI":"10.1073\/pnas.1206641109","article-title":"Resolvin E1 promotes phagocytosis-induced neutrophil apoptosis and accelerates resolution of pulmonary inflammation","volume":"109","author":"El Kebir","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.autrev.2025.103896_bb0170","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.cell.2011.12.023","article-title":"Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections","volume":"148","author":"Tobin","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.autrev.2025.103896_bb0175","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.cell.2013.02.027","article-title":"The lipid mediator Protectin D1 inhibits influenza virus replication and improves severe influenza","volume":"153","author":"Morita","year":"2013","journal-title":"Cell"},{"key":"10.1016\/j.autrev.2025.103896_bb0180","first-page":"496","article-title":"Role of omega-3 PUFA-derived mediators, the protectins, in influenza virus infection","volume":"1851","author":"Imai","year":"2015","journal-title":"Biochim Biophys Acta (BBA) Mol Cell Biol Lipids"},{"key":"10.1016\/j.autrev.2025.103896_bb0185","doi-asserted-by":"crossref","first-page":"6031","DOI":"10.4049\/jimmunol.1302795","article-title":"The specialized proresolving mediator 17-HDHA enhances the antibody-mediated immune response against influenza virus: a new class of Adjuvant?","volume":"193","author":"Ramon","year":"2014","journal-title":"J Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0190","doi-asserted-by":"crossref","first-page":"3343","DOI":"10.4049\/jimmunol.1700503","article-title":"Lipoxin B4 enhances human memory B cell antibody production via upregulating Cyclooxygenase-2 expression","volume":"201","author":"Kim","year":"2018","journal-title":"J Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0195","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.3389\/fimmu.2020.01130","article-title":"Severe COVID-19, another piece in the puzzle of the hyperferritinemic syndrome. An immunomodulatory perspective to alleviate the storm","volume":"11","author":"Ruscitti","year":"2020","journal-title":"Front Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0200","doi-asserted-by":"crossref","first-page":"2731","DOI":"10.1172\/JCI60331","article-title":"The acute respiratory distress syndrome","volume":"122","author":"Matthay","year":"2012","journal-title":"J Clin Invest"},{"key":"10.1016\/j.autrev.2025.103896_bb0205","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202001952R","article-title":"Resolvin D1 and D2 reduce SARS-CoV-2-induced inflammatory responses in cystic fibrosis macrophages","volume":"35","author":"Recchiuti","year":"2021","journal-title":"FASEB J"},{"key":"10.1016\/j.autrev.2025.103896_bb0210","doi-asserted-by":"crossref","first-page":"581","DOI":"10.3389\/fimmu.2020.00581","article-title":"Resolvin D1 reduces lung infection and inflammation activating resolution in cystic fibrosis","volume":"11","author":"Isopi","year":"2020","journal-title":"Front Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0215","first-page":"14","article-title":"The specialized pro-resolving lipid mediator Protectin D1 affects macrophages differentiation and activity in Adult-onset Still\u2019s disease and COVID-19, two hyperinflammatory diseases sharing similar transcriptomic profiles","author":"Navarini","year":"2023","journal-title":"Front Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.metabol.2020.154319","article-title":"Visceral fat shows the strongest association with the need of intensive care in patients with COVID-19","volume":"111","author":"Watanabe","year":"2020","journal-title":"Metabolism"},{"key":"10.1016\/j.autrev.2025.103896_bb0225","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.3389\/fimmu.2020.01997","article-title":"Obesity-driven deficiencies of specialized pro-resolving mediators may drive adverse outcomes during SARS-CoV-2 infection","volume":"11","author":"Pal","year":"2020","journal-title":"Front Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0230","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.freeradbiomed.2020.07.005","article-title":"Potential benefits and risks of omega-3 fatty acids supplementation to patients with COVID-19","volume":"156","author":"Rogero","year":"2020","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.autrev.2025.103896_bb0235","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2020.624657","article-title":"Stimulating the resolution of inflammation through Omega-3 polyunsaturated fatty acids in COVID-19: rationale for the COVID-Omega-F trial","volume":"11","author":"Arnardottir","year":"2021","journal-title":"Front Physiol"},{"key":"10.1016\/j.autrev.2025.103896_bb0240","doi-asserted-by":"crossref","first-page":"266","DOI":"10.4049\/jimmunol.138.1.266","article-title":"Lipoxin A-induced inhibition of human natural killer cell cytotoxicity: studies on stereospecificity of inhibition and mode of action","volume":"138","author":"Ramstedt","year":"1987","journal-title":"J Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0245","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.3004812","article-title":"Lipoxin A4 regulates natural killer cell and type 2 innate lymphoid cell activation in asthma","volume":"5","author":"Barnig","year":"2013","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.autrev.2025.103896_bb0250","doi-asserted-by":"crossref","first-page":"6129","DOI":"10.4049\/jimmunol.1004007","article-title":"NK cells are effectors for Resolvin E1 in the timely resolution of allergic airway inflammation","volume":"186","author":"Haworth","year":"2011","journal-title":"J Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0255","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.immuni.2014.09.005","article-title":"Development, differentiation, and diversity of innate lymphoid cells","volume":"41","author":"Diefenbach","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.autrev.2025.103896_bb0260","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1038\/ni.2131","article-title":"Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus","volume":"12","author":"Monticelli","year":"2011","journal-title":"Nat Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0265","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1111\/imr.12702","article-title":"Type 2 innate lymphoid cells in the induction and resolution of tissue inflammation","volume":"286","author":"Wallrapp","year":"2018","journal-title":"Immunol Rev"},{"key":"10.1016\/j.autrev.2025.103896_bb0270","doi-asserted-by":"crossref","first-page":"3331","DOI":"10.4049\/jimmunol.0903022","article-title":"Cutting edge: a critical role for the G protein-coupled receptor mFPR2 in airway inflammation and immune responses","volume":"184","author":"Chen","year":"2010","journal-title":"J Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0275","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1038\/ni745","article-title":"Lipoxin-mediated inhibition of IL-12 production by DCs: a mechanism for regulation of microbial immunity","volume":"3","author":"Aliberti","year":"2002","journal-title":"Nat Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0280","doi-asserted-by":"crossref","first-page":"5944","DOI":"10.1167\/iovs.14-14356","article-title":"The Resolvin D1 analogue controls maturation of dendritic cells and suppresses alloimmunity in corneal transplantation","volume":"55","author":"Hua","year":"2014","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.autrev.2025.103896_bb0285","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1586\/eci.12.22","article-title":"Stability of T-cell lineages in autoimmune diseases","volume":"8","author":"Raphael","year":"2012","journal-title":"Expert Rev Clin Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0290","doi-asserted-by":"crossref","first-page":"2724","DOI":"10.1172\/JCI97951","article-title":"Key roles for lipid mediators in the adaptive immune response","volume":"128","author":"Duffney","year":"2018","journal-title":"J Clin Invest"},{"key":"10.1016\/j.autrev.2025.103896_bb0295","doi-asserted-by":"crossref","first-page":"43079","DOI":"10.1074\/jbc.M509796200","article-title":"The docosatriene protectin D1 is produced by TH2 skewing and promotes human T cell apoptosis via lipid raft clustering","volume":"280","author":"Ariel","year":"2005","journal-title":"J Biol Chem"},{"key":"10.1016\/j.autrev.2025.103896_bb0300","first-page":"8","article-title":"Proresolving lipid mediators resolvin D1, resolvin D2, and maresin 1 are critical in modulating T cell responses","author":"Chiurchi\u00f9","year":"2016","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.autrev.2025.103896_bb0305","doi-asserted-by":"crossref","first-page":"6266","DOI":"10.4049\/jimmunol.170.12.6266","article-title":"Aspirin-triggered Lipoxin A4 and B4 analogs block extracellular signal-regulated kinase-dependent TNF-\u03b1 secretion from human T cells","volume":"170","author":"Ariel","year":"2003","journal-title":"J Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0310","doi-asserted-by":"crossref","first-page":"30697","DOI":"10.1074\/jbc.M115.679068","article-title":"Untargeted plasma metabolomics identifies endogenous metabolite with drug-like properties in chronic animal model of multiple sclerosis","volume":"290","author":"Poisson","year":"2015","journal-title":"J Biol Chem"},{"key":"10.1016\/j.autrev.2025.103896_bb0315","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.intimp.2010.10.006","article-title":"Comparative analysis of Annexin A1-formyl peptide receptor 2\/ALX expression in human leukocyte subsets","volume":"11","author":"Spurr","year":"2011","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.autrev.2025.103896_bb0320","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.4049\/jimmunol.1103483","article-title":"Specialized proresolving mediators enhance human B cell differentiation to antibody-secreting cells","volume":"189","author":"Ramon","year":"2012","journal-title":"J Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0325","doi-asserted-by":"crossref","first-page":"4738","DOI":"10.4049\/jimmunol.1601031","article-title":"B cell activity is impaired in human and mouse obesity and is responsive to an essential fatty acid upon murine influenza infection","volume":"198","author":"Kosaraju","year":"2017","journal-title":"J Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0330","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1189\/jlb.0812394","article-title":"DHA-enriched fish oil targets B cell lipid microdomains and enhances ex vivo and in vivo B cell function","volume":"93","author":"Gurzell","year":"2013","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.autrev.2025.103896_bb0335","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1194\/jlr.M049809","article-title":"Eicosapentaenoic and docosahexaenoic acid ethyl esters differentially enhance B-cell activity in murine obesity","volume":"55","author":"Teague","year":"2014","journal-title":"J Lipid Res"},{"key":"10.1016\/j.autrev.2025.103896_bb0340","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1194\/jlr.M000851","article-title":"n-3 PUFA improves fatty acid composition, prevents palmitate-induced apoptosis, and differentially modifies B cell cytokine secretion in vitro and ex vivo","volume":"51","author":"Rockett","year":"2010","journal-title":"J Lipid Res"},{"key":"10.1016\/j.autrev.2025.103896_bb0345","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1373\/clinchem.2012.190199","article-title":"Resolvins D1, D2, and other mediators of self-limited resolution of inflammation in human blood following n-3 fatty acid supplementation","volume":"58","author":"Mas","year":"2012","journal-title":"Clin Chem"},{"key":"10.1016\/j.autrev.2025.103896_bb0350","doi-asserted-by":"crossref","first-page":"2205","DOI":"10.1056\/NEJMra1004965","article-title":"The pathogenesis of rheumatoid arthritis","volume":"365","author":"McInnes","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1016\/j.autrev.2025.103896_bb0355","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1172\/JCI200113416","article-title":"Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes","volume":"108","author":"Tilley","year":"2001","journal-title":"J Clin Invest"},{"key":"10.1016\/j.autrev.2025.103896_bb0360","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/S0889-857X(21)00465-8","article-title":"Eicosanoids in rheumatoid arthritis","volume":"21","author":"Sperling","year":"1995","journal-title":"Rheum Dis Clin North Am"},{"key":"10.1016\/j.autrev.2025.103896_bb0365","doi-asserted-by":"crossref","first-page":"S171","DOI":"10.1017\/S0007114512001560","article-title":"Influence of marine n -3 polyunsaturated fatty acids on immune function and a systematic review of their effects on clinical outcomes in rheumatoid arthritis","volume":"107","author":"Miles","year":"2012","journal-title":"Br J Nutr"},{"key":"10.1016\/j.autrev.2025.103896_bb0370","doi-asserted-by":"crossref","first-page":"6418","DOI":"10.4049\/jimmunol.0903816","article-title":"Resolution of inflammation in murine autoimmune arthritis is disrupted by Cyclooxygenase-2 inhibition and restored by Prostaglandin E2-Mediated Lipoxin A4 production","volume":"184","author":"Chan","year":"2010","journal-title":"J Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0375","doi-asserted-by":"crossref","first-page":"3383","DOI":"10.4049\/jimmunol.0900327","article-title":"12\/15-Lipoxygenase counteracts inflammation and tissue damage in arthritis","volume":"183","author":"Kr\u00f6nke","year":"2009","journal-title":"J Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0380","doi-asserted-by":"crossref","first-page":"3076","DOI":"10.4049\/jimmunol.1003473","article-title":"5-Lipoxygenase\u2013deficient mice infected with Borrelia burgdorferi develop persistent arthritis","volume":"186","author":"Blaho","year":"2011","journal-title":"J Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0385","doi-asserted-by":"crossref","first-page":"R83","DOI":"10.1186\/ar2717","article-title":"Expression of 5-lipoxygenase and 15-lipoxygenase in rheumatoid arthritis synovium and effects of intraarticular glucocorticoids","volume":"11","author":"Gheorghe","year":"2009","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.autrev.2025.103896_bb0390","first-page":"2144","article-title":"Antiinflammatory mediator lipoxin A4 and its receptor in synovitis of patients with rheumatoid arthritis","volume":"34","author":"Hashimoto","year":"2007","journal-title":"J Rheumatol"},{"key":"10.1016\/j.autrev.2025.103896_bb0395","first-page":"1415","article-title":"Lipid and lipid mediator profiling of human synovial fluid in rheumatoid arthritis patients by means of LC\u2013MS\/MS","volume":"1821","author":"Giera","year":"2012","journal-title":"Biochim Biophys Acta (BBA) Mol Cell Biol Lipids"},{"key":"10.1016\/j.autrev.2025.103896_bb0400","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2022.103974","article-title":"MCTR3 reprograms arthritic monocytes to upregulate Arginase-1 and exert pro-resolving and tissue-protective functions in experimental arthritis","volume":"79","author":"Pistorius","year":"2022","journal-title":"eBioMedicine"},{"key":"10.1016\/j.autrev.2025.103896_bb0405","doi-asserted-by":"crossref","first-page":"2362","DOI":"10.4049\/jimmunol.1502268","article-title":"Resolvin D3 is dysregulated in arthritis and reduces arthritic inflammation","volume":"197","author":"Arnardottir","year":"2016","journal-title":"J Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0410","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/s13075-020-2133-2","article-title":"Resolvin D1 suppresses pannus formation via decreasing connective tissue growth factor caused by upregulation of miRNA-146a-5p in rheumatoid arthritis","volume":"22","author":"Sun","year":"2020","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.autrev.2025.103896_bb0415","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/j.autrev.2013.12.004","article-title":"Th17 and regulatory T cell balance in autoimmune and inflammatory diseases","volume":"13","author":"Noack","year":"2014","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.autrev.2025.103896_bb0420","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1136\/annrheumdis-2018-213511","article-title":"Maresin 1 improves the Treg\/Th17 imbalance in rheumatoid arthritis through miR-21","volume":"77","author":"Jin","year":"2018","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.autrev.2025.103896_bb0425","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1038\/s41419-021-03562-6","article-title":"Protectin DX restores Treg\/Th17 cell balance in rheumatoid arthritis by inhibiting NLRP3 inflammasome via miR-20a","volume":"12","author":"Jin","year":"2021","journal-title":"Cell Death Dis"},{"key":"10.1016\/j.autrev.2025.103896_bb0430","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.125191","article-title":"Inflammatory arthritis disrupts gut resolution mechanisms, promoting barrier breakdown by Porphyromonas gingivalis","volume":"4","author":"Flak","year":"2019","journal-title":"JCI Insight"},{"key":"10.1016\/j.autrev.2025.103896_bb0435","doi-asserted-by":"crossref","first-page":"5420","DOI":"10.1038\/s41467-020-19176-z","article-title":"Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis","volume":"11","author":"Gomez","year":"2020","journal-title":"Nat Commun"},{"key":"10.1016\/j.autrev.2025.103896_bb0440","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1038\/s41590-020-0677-6","article-title":"Autoimmunity and organ damage in systemic lupus erythematosus","volume":"21","author":"Tsokos","year":"2020","journal-title":"Nat Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0445","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1038\/ni1392","article-title":"Apoptotic neutrophils and T cells sequester chemokines during immune response resolution through modulation of CCR5 expression","volume":"7","author":"Ariel","year":"2006","journal-title":"Nat Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0450","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2018\/5264195","article-title":"Role of the specialized proresolving mediator Resolvin D1 in systemic lupus erythematosus: preliminary results","volume":"2018","author":"Navarini","year":"2018","journal-title":"J Immunol Res"},{"key":"10.1016\/j.autrev.2025.103896_bb0455","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.668760","article-title":"Resolvin D1 improves the Treg\/Th17 imbalance in systemic lupus erythematosus through miR-30e-5p","volume":"12","author":"Cheng","year":"2021","journal-title":"Front Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0460","doi-asserted-by":"crossref","DOI":"10.1016\/j.autrev.2020.102738","article-title":"The growing role of precision medicine for the treatment of autoimmune diseases; results of a systematic review of literature and Experts\u2019 Consensus","volume":"20","author":"Giacomelli","year":"2021","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.autrev.2025.103896_bb0465","doi-asserted-by":"crossref","first-page":"C178","DOI":"10.1152\/ajpcell.00284.2013","article-title":"ALX\/FPR2 receptor for RvD1 is expressed and functional in salivary glands","volume":"306","author":"Nelson","year":"2014","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1016\/j.autrev.2025.103896_bb0470","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1177\/0022034513519108","article-title":"Expression of resolvin D1 biosynthetic pathways in salivary epithelium","volume":"93","author":"Leigh","year":"2014","journal-title":"J Dent Res"},{"key":"10.1016\/j.autrev.2025.103896_bb0475","doi-asserted-by":"crossref","first-page":"C1331","DOI":"10.1152\/ajpcell.00207.2011","article-title":"Resolvin D1 prevents TNF-\u03b1-mediated disruption of salivary epithelial formation","volume":"302","author":"Odusanwo","year":"2012","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1016\/j.autrev.2025.103896_bb0480","doi-asserted-by":"crossref","first-page":"45525","DOI":"10.1038\/srep45525","article-title":"AT-RvD1 promotes resolution of inflammation in NOD\/ShiLtJ mice","volume":"7","author":"Wang","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.autrev.2025.103896_bb0485","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1093\/rheumatology\/kez072","article-title":"Aspirin Triggered Resolvin D1 reduces inflammation and restores saliva secretion in a Sj\u00f6gren\u2019s syndrome mouse model","volume":"58","author":"Dean","year":"2019","journal-title":"Rheumatology"},{"key":"10.1016\/j.autrev.2025.103896_bb0490","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1089\/hum.1996.7.9-1085","article-title":"Immediate inflammatory responses to adenovirus-mediated gene transfer in rat salivary glands","volume":"7","author":"Adesanya","year":"1996","journal-title":"Hum Gene Ther"},{"key":"10.1016\/j.autrev.2025.103896_bb0495","first-page":"1","article-title":"Aspirin-Triggered Resolvin D1 versus Dexamethasone in the treatment of Sj\u00f6gren\u2019s Syndrome-Like NOD\/ShiLtJ mice - a pilot study","author":"Easley","year":"2015","journal-title":"J Rheum Dis Treat"},{"key":"10.1016\/j.autrev.2025.103896_bb0500","first-page":"1573","article-title":"Criteria for the classification of early systemic sclerosis","volume":"28","author":"LeRoy","year":"2001","journal-title":"J Rheumatol"},{"key":"10.1016\/j.autrev.2025.103896_bb0505","doi-asserted-by":"crossref","first-page":"5902","DOI":"10.4049\/jimmunol.177.9.5902","article-title":"Resolvin D series and Protectin D1 mitigate acute kidney injury","volume":"177","author":"Duffield","year":"2006","journal-title":"J Immunol"},{"key":"10.1016\/j.autrev.2025.103896_bb0510","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ejphar.2018.07.054","article-title":"DHA attenuates hepatic ischemia reperfusion injury by inhibiting pyroptosis and activating PI3K\/Akt pathway","volume":"835","author":"Li","year":"2018","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.autrev.2025.103896_bb0515","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.1111\/bph.14212","article-title":"Resolvin D1 attenuates liver ischaemia\/reperfusion injury through modulating thioredoxin 2-mediated mitochondrial quality control: Role of resolvin D1 in mitochondrial quality control","volume":"175","author":"Kang","year":"2018","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.autrev.2025.103896_bb0520","first-page":"1111","article-title":"Role and related mechanism of resolvin D1 in lung ischemia reperfusion injury in rats","volume":"99","author":"Xia","year":"2019","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"10.1016\/j.autrev.2025.103896_bb0525","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.autrev.2011.04.025","article-title":"Systemic sclerosis refractory disease: from the skin to the heart","volume":"10","author":"Almeida","year":"2011","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.autrev.2025.103896_bb0530","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.3892\/etm.2014.1641","article-title":"Resolvin E1 reduces hepatic fibrosis in mice with Schistosoma japonicum infection","volume":"7","author":"Qiu","year":"2014","journal-title":"Exp Therap Med"},{"key":"10.1016\/j.autrev.2025.103896_bb0535","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1002\/path.4050","article-title":"Resolvins E1 and D1 inhibit interstitial fibrosis in the obstructed kidney via inhibition of local fibroblast proliferation: Resolvins prevent fibrosis via inhibition of fibroblast proliferation","volume":"228","author":"Qu","year":"2012","journal-title":"J Pathol"},{"key":"10.1016\/j.autrev.2025.103896_bb0540","article-title":"17(R)-resolvin D1 ameliorates bleomycin-induced pulmonary fibrosis in mice","volume":"3","author":"Yatomi","year":"2015","journal-title":"Phys Rep"},{"key":"10.1016\/j.autrev.2025.103896_bb0545","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.yjmcc.2015.04.003","article-title":"Resolvin D1 activates the inflammation resolving response at splenic and ventricular site following myocardial infarction leading to improved ventricular function","volume":"84","author":"Kain","year":"2015","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.autrev.2025.103896_bb0550","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.jnutbio.2018.09.012","article-title":"Reduction of high-fat diet-induced liver proinflammatory state by eicosapentaenoic acid plus hydroxytyrosol supplementation: involvement of resolvins RvE1\/2 and RvD1\/2","volume":"63","author":"Echeverr\u00eda","year":"2019","journal-title":"J Nutr Biochem"},{"key":"10.1016\/j.autrev.2025.103896_bb0555","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1136\/ard.47.10.793","article-title":"Influence of diet with different lipid composition on neutrophil chemiluminescence and disease activity in patients with rheumatoid arthritis","volume":"47","author":"Magaro","year":"1988","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.autrev.2025.103896_bb0560","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.nut.2017.06.023","article-title":"Intake of \u03c9-3 polyunsaturated fatty acids in patients with rheumatoid arthritis: a systematic review and meta-analysis","volume":"45","author":"Gioxari","year":"2018","journal-title":"Nutrition"},{"key":"10.1016\/j.autrev.2025.103896_bb0565","doi-asserted-by":"crossref","first-page":"3506","DOI":"10.3390\/nu13103506","article-title":"Dietary interventions with or without Omega-3 supplementation for the management of rheumatoid arthritis: a systematic review","volume":"13","author":"Raad","year":"2021","journal-title":"Nutrients"},{"key":"10.1016\/j.autrev.2025.103896_bb0570","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1002\/art.42811","article-title":"Vitamin D and Marine n-3 fatty acids for autoimmune disease prevention: outcomes two years after completion of a double-blind","volume":"76","author":"Costenbader","year":"2024","journal-title":"Placebo-Control Trial Arthritis Rheumatol"},{"key":"10.1016\/j.autrev.2025.103896_bb0575","doi-asserted-by":"crossref","first-page":"1356207","DOI":"10.3389\/fnut.2024.1356207","article-title":"Assessment of causal relationships between omega-3 and omega-6 polyunsaturated fatty acids in autoimmune rheumatic diseases: a brief research report from a Mendelian randomization study","volume":"11","author":"Xu","year":"2024","journal-title":"Front Nutr"},{"key":"10.1016\/j.autrev.2025.103896_bb0580","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s00296-002-0234-7","article-title":"Anti-inflammatory effects of a low arachidonic acid diet and fish oil in patients with rheumatoid arthritis","volume":"23","author":"Adam","year":"2003","journal-title":"Rheumatol Int"},{"key":"10.1016\/j.autrev.2025.103896_bb0585","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1093\/rheumatology\/ken024","article-title":"Cod liver oil (n-3 fatty acids) as an non-steroidal anti-inflammatory drug sparing agent in rheumatoid arthritis","volume":"47","author":"Galarraga","year":"2008","journal-title":"Rheumatology"},{"key":"10.1016\/j.autrev.2025.103896_bb0590","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.nut.2016.12.003","article-title":"Effect of \u03c9-3 polyunsaturated fatty acids on arthritic pain: a systematic review","volume":"39\u201340","author":"Abdulrazaq","year":"2017","journal-title":"Nutrition"},{"key":"10.1016\/j.autrev.2025.103896_bb0595","doi-asserted-by":"crossref","first-page":"3050","DOI":"10.3390\/nu13093050","article-title":"Increased levels of Omega-3 fatty acids and DHA are linked to pain reduction in Rheumatoid Arthritis patients treated with Janus Kinase Inhibitors","volume":"13","author":"Chang","year":"2021","journal-title":"Nutrients"},{"key":"10.1016\/j.autrev.2025.103896_bb0600","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1016\/j.clnu.2017.02.021","article-title":"Docosahexaenoic acid in the treatment of rheumatoid arthritis: a double-blind, placebo-controlled, randomized cross-over study with microalgae vs. sunflower oil","volume":"37","author":"Dawczynski","year":"2018","journal-title":"Clin Nutr"},{"key":"10.1016\/j.autrev.2025.103896_bb0605","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1186\/1476-511X-10-130","article-title":"Incorporation of n-3 PUFA and \u03b3-linolenic acid in blood lipids and red blood cell lipids together with their influence on disease activity in patients with chronic inflammatory arthritis - a randomized controlled human intervention trial","volume":"10","author":"Dawczynski","year":"2011","journal-title":"Lipids Health Dis"},{"key":"10.1016\/j.autrev.2025.103896_bb0610","doi-asserted-by":"crossref","first-page":"1949","DOI":"10.1136\/annrheumdis-2013-203338","article-title":"Long-term intake of dietary long-chain n-3 polyunsaturated fatty acids and risk of rheumatoid arthritis: a prospective cohort study of women","volume":"73","author":"Di Giuseppe","year":"2014","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.autrev.2025.103896_bb0615","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.1016\/j.jand.2018.04.005","article-title":"Dietary long-chain n-3 fatty acid intake and arthritis risk in the women\u2019s health initiative","volume":"118","author":"Krok-Schoen","year":"2018","journal-title":"J Acad Nutr Diet"},{"key":"10.1016\/j.autrev.2025.103896_bb0620","doi-asserted-by":"crossref","DOI":"10.1016\/j.autrev.2020.102688","article-title":"Effect of omega-3 fatty acids on systemic lupus erythematosus disease activity: a systematic review and meta-analysis","volume":"19","author":"Duarte-Garc\u00eda","year":"2020","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.autrev.2025.103896_bb0625","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1177\/09612033211067985","article-title":"The effect of Omega-3 fatty acid supplementation in systemic lupus erythematosus patients: a systematic review","volume":"31","author":"Ramessar","year":"2022","journal-title":"Lupus"},{"key":"10.1016\/j.autrev.2025.103896_bb0630","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1186\/s12937-015-0068-2","article-title":"Placebo-controlled randomized clinical trial of fish oil\u2019s impact on fatigue, quality of life, and disease activity in Systemic Lupus Erythematosus","volume":"14","author":"Arriens","year":"2015","journal-title":"Nutr J"},{"key":"10.1016\/j.autrev.2025.103896_bb0635","first-page":"65","article-title":"Fish oil enhanced the efficacy of low-dose cyclophosphamide regimen for proliferative lupus nephritis: a randomized controlled double-blind trial","author":"Zhang","year":"2021","journal-title":"Food Nutr Res"},{"key":"10.1016\/j.autrev.2025.103896_bb0640","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1136\/ard.2007.077156","article-title":"A randomised interventional trial of -3-polyunsaturated fatty acids on endothelial function and disease activity in systemic lupus erythematosus","volume":"67","author":"Wright","year":"2008","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.autrev.2025.103896_bb0645","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2023.111299","article-title":"\u03c9-3 polyunsaturated fatty acid alleviates systemic lupus erythematosus by suppressing autoimmunity in a murine model","volume":"126","author":"Liu","year":"2024","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.autrev.2025.103896_bb0650","doi-asserted-by":"crossref","DOI":"10.1136\/lupus-2024-001201","article-title":"Correction of omega-3 fatty acid deficiency and improvement in disease activity in patients with systemic lupus erythematosus treated with krill oil concentrate: a multicentre, randomised, double-blind, placebo-controlled trial","volume":"11","author":"Salmon","year":"2024","journal-title":"Lupus Sci Med"},{"key":"10.1016\/j.autrev.2025.103896_bb0655","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1177\/09612033221140724","article-title":"Omega-3 fatty acids: current insights into mechanisms of action in systemic lupus erythematosus","volume":"32","author":"Salek","year":"2023","journal-title":"Lupus"},{"key":"10.1016\/j.autrev.2025.103896_bb0660","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1111\/j.1754-4505.2010.00158.x","article-title":"Effect of omega-3 and vitamin E supplementation on dry mouth in patients with Sj\u00f6gren\u2019s syndrome","volume":"30","author":"Singh","year":"2010","journal-title":"Spec Care Dentist"},{"key":"10.1016\/j.autrev.2025.103896_bb0665","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1089\/jop.2010.0019","article-title":"Resolvin E1 improves tear production and decreases inflammation in a dry eye mouse model","volume":"26","author":"Li","year":"2010","journal-title":"J Ocul Pharmacol Ther"},{"key":"10.1016\/j.autrev.2025.103896_bb0670","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1186\/s10020-024-00877-w","article-title":"Low-dose pro-resolving mediators temporally reset the resolution response to microbial inflammation","volume":"30","author":"Serhan","year":"2024","journal-title":"Mol Med"},{"key":"10.1016\/j.autrev.2025.103896_bb0675","doi-asserted-by":"crossref","first-page":"169","DOI":"10.3389\/fphar.2019.00169","article-title":"Development of an optimized LC-MS method for the detection of specialized pro-resolving mediators in biological samples","volume":"10","author":"Kutzner","year":"2019","journal-title":"Front Pharmacol"},{"key":"10.1016\/j.autrev.2025.103896_bb0680","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1021\/jasms.4c00211","article-title":"Development and validation of methodologies for the identification of specialized pro-resolving lipid mediators and classic eicosanoids in biological matrices","volume":"35","author":"Dooley","year":"2024","journal-title":"J Am Soc Mass Spectrom"},{"key":"10.1016\/j.autrev.2025.103896_bb0685","doi-asserted-by":"crossref","first-page":"C39","DOI":"10.1152\/ajpcell.00024.2014","article-title":"Identification and signature profiles for pro-resolving and inflammatory lipid mediators in human tissue","volume":"307","author":"Colas","year":"2014","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1016\/j.autrev.2025.103896_bb0690","doi-asserted-by":"crossref","first-page":"353","DOI":"10.3390\/biom12030353","article-title":"Utility of the specialized pro-resolving mediators as diagnostic and prognostic biomarkers in disease","volume":"12","author":"Dalli","year":"2022","journal-title":"Biomolecules"},{"key":"10.1016\/j.autrev.2025.103896_bb0695","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/s12998-025-00575-2","article-title":"Preliminary insights into the effects of spinal manipulation therapy of different force magnitudes on blood biomarkers of oxidative stress and pro-resolution of inflammation mediators","volume":"33","author":"Duarte","year":"2025","journal-title":"Chiropr Man Therap"}],"container-title":["Autoimmunity Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568997225001570?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568997225001570?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T23:51:24Z","timestamp":1763769084000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1568997225001570"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":139,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["S1568997225001570"],"URL":"https:\/\/doi.org\/10.1016\/j.autrev.2025.103896","relation":{},"ISSN":["1568-9972"],"issn-type":[{"value":"1568-9972","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Specialized pro-resolving mediators and autoimmunity: Recent insights and future perspectives","name":"articletitle","label":"Article Title"},{"value":"Autoimmunity Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.autrev.2025.103896","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"103896"}}