{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T00:42:28Z","timestamp":1793925748150,"version":"4.8.0"},"reference-count":219,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82373476"],"award-info":[{"award-number":["82373476"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82200064"],"award-info":[{"award-number":["82200064"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Autoimmunity Reviews"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.autrev.2025.103977","type":"journal-article","created":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T16:39:45Z","timestamp":1766594385000},"page":"103977","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["The Trm-Treg Axis as a tissue-encoded immune checkpoint in chronic inflammation and autoimmunity"],"prefix":"10.1016","volume":"25","author":[{"given":"Liang","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumin","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yale","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.autrev.2025.103977_bb0005","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1038\/s41577-021-00538-7","article-title":"Does the epithelial barrier hypothesis explain the increase in allergy, autoimmunity and other chronic conditions?","volume":"21","author":"Akdis","year":"2021","journal-title":"Nat Rev Immunol"},{"issue":"5","key":"10.1016\/j.autrev.2025.103977_bb0010","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1111\/all.15240","article-title":"Epithelial barrier hypothesis: effect of the external exposome on the microbiome and epithelial barriers in allergic disease","volume":"77","author":"Celebi Sozener","year":"2022","journal-title":"Allergy"},{"issue":"6","key":"10.1016\/j.autrev.2025.103977_bb0015","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1016\/j.jaci.2020.04.024","article-title":"Environmental factors in epithelial barrier dysfunction","volume":"145","author":"Celebi S\u00f6zener","year":"2020","journal-title":"J Allergy Clin Immunol"},{"issue":"10","key":"10.1016\/j.autrev.2025.103977_bb0020","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.1016\/j.cell.2023.03.031","article-title":"A tissue injury sensing and repair pathway distinct from host pathogen defense","volume":"186","author":"Liu","year":"2023","journal-title":"Cell"},{"issue":"62","key":"10.1016\/j.autrev.2025.103977_bb0025","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.abg2329","article-title":"Regulatory T cells promote innate inflammation after skin barrier breach via TGF-\u03b2 activation","volume":"6","author":"Moreau","year":"2021","journal-title":"Sci Immunol."},{"issue":"6","key":"10.1016\/j.autrev.2025.103977_bb0030","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1007\/s13238-021-00882-3","article-title":"Aging weakens Th17 cell pathogenicity and ameliorates experimental autoimmune uveitis in mice","volume":"13","author":"Li","year":"2022","journal-title":"Protein Cell"},{"issue":"7789","key":"10.1016\/j.autrev.2025.103977_bb0035","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1038\/s41586-019-1844-5","article-title":"Somatic inflammatory gene mutations in human ulcerative colitis epithelium","volume":"577","author":"Nanki","year":"2020","journal-title":"Nature"},{"issue":"33","key":"10.1016\/j.autrev.2025.103977_bb0040","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abo5871","article-title":"The evolving role of tissue-resident memory T cells in infections and cancer","volume":"8","author":"Yenyuwadee","year":"2022","journal-title":"Sci Adv"},{"issue":"12","key":"10.1016\/j.autrev.2025.103977_bb0045","doi-asserted-by":"crossref","first-page":"1828","DOI":"10.1038\/s43587-024-00746-5","article-title":"Age-related decline in CD8+ tissue resident memory T cells compromises antitumor immunity","volume":"4","author":"Pei","year":"2024","journal-title":"Nat Aging"},{"issue":"5","key":"10.1016\/j.autrev.2025.103977_bb0050","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/j.jhep.2022.06.014","article-title":"NUDT1 promotes the accumulation and longevity of CD103+ TRM cells in primary biliary cholangitis","volume":"77","author":"Huang","year":"2022","journal-title":"J Hepatol"},{"issue":"2","key":"10.1016\/j.autrev.2025.103977_bb0055","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20220275","article-title":"Human CARMIL2 deficiency underlies a broader immunological and clinical phenotype than CD28 deficiency","volume":"220","author":"L\u00e9vy","year":"2023","journal-title":"J Exp Med"},{"issue":"9","key":"10.1016\/j.autrev.2025.103977_bb0060","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1177\/1352458520963937","article-title":"PRF1 mutation alters immune system activation, inflammation, and risk of autoimmunity","volume":"27","author":"Sidore","year":"2021","journal-title":"Mult Scler Houndmills Basingstoke Engl"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0065","doi-asserted-by":"crossref","first-page":"5579","DOI":"10.1038\/s41467-023-41364-w","article-title":"CD8+ tissue-resident memory T-cell development depends on infection-matching regulatory T-cell types","volume":"14","author":"Barros","year":"2023","journal-title":"Nat Commun"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0070","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1038\/s41385-021-00456-w","article-title":"The fellowship of regulatory and tissue-resident memory cells","volume":"15","author":"Barros","year":"2022","journal-title":"Mucosal Immunol"},{"issue":"3","key":"10.1016\/j.autrev.2025.103977_bb0075","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1053\/j.gastro.2023.05.041","article-title":"Hypusination maintains intestinal homeostasis and prevents colitis and carcinogenesis by enhancing aldehyde detoxification","volume":"165","author":"Gobert","year":"2023","journal-title":"Gastroenterology"},{"key":"10.1016\/j.autrev.2025.103977_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2024.105136","article-title":"MDA5-autoimmunity and interstitial pneumonitis contemporaneous with the COVID-19 pandemic (MIP-C)","volume":"104","author":"David","year":"2024","journal-title":"EBioMedicine"},{"issue":"7","key":"10.1016\/j.autrev.2025.103977_bb0085","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.3748\/wjg.v29.i7.1157","article-title":"Mucosal healing and inflammatory bowel disease: therapeutic implications and new targets","volume":"29","author":"Otte","year":"2023","journal-title":"World J Gastroenterol"},{"issue":"55","key":"10.1016\/j.autrev.2025.103977_bb0090","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.abe2749","article-title":"Persistence of mature dendritic cells, TH2A, and Tc2 cells characterize clinically resolved atopic dermatitis under IL-4R\u03b1 blockade","volume":"6","author":"Bangert","year":"2021","journal-title":"Sci Immunol."},{"issue":"70","key":"10.1016\/j.autrev.2025.103977_bb0095","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.abl9165","article-title":"Classification of human chronic inflammatory skin disease based on single-cell immune profiling","volume":"7","author":"Liu","year":"2022","journal-title":"Sci Immunol."},{"issue":"55","key":"10.1016\/j.autrev.2025.103977_bb0100","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.abb6852","article-title":"Tissue-resident CD4+ T helper cells assist the development of protective respiratory B and CD8+ T cell memory responses","volume":"6","author":"Son","year":"2021","journal-title":"Sci Immunol"},{"issue":"7","key":"10.1016\/j.autrev.2025.103977_bb0105","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1038\/s41590-023-01538-6","article-title":"Human circulating and tissue-resident memory CD8+ T cells","volume":"24","author":"Buggert","year":"2023","journal-title":"Nat Immunol"},{"issue":"4","key":"10.1016\/j.autrev.2025.103977_bb0110","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1016\/j.immuni.2013.03.004","article-title":"Human CD1c+ dendritic cells drive the differentiation of CD103+ CD8+ mucosal effector T cells via the cytokine TGF-\u03b2","volume":"38","author":"Yu","year":"2013","journal-title":"Immunity"},{"issue":"11","key":"10.1016\/j.autrev.2025.103977_bb0115","doi-asserted-by":"crossref","first-page":"2615","DOI":"10.1016\/j.immuni.2024.09.015","article-title":"Retinoic acid and TGF-\u03b2 orchestrate organ-specific programs of tissue residency","volume":"57","author":"Obers","year":"2024","journal-title":"Immunity"},{"issue":"7","key":"10.1016\/j.autrev.2025.103977_bb0120","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1038\/s41590-022-01229-8","article-title":"Tissue-resident memory CD8+ T cells possess unique transcriptional, epigenetic and functional adaptations to different tissue environments","volume":"23","author":"Crowl","year":"2022","journal-title":"Nat Immunol"},{"issue":"6674","key":"10.1016\/j.autrev.2025.103977_bb0125","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1126\/science.adi8885","article-title":"Divergent molecular networks program functionally distinct CD8+ skin-resident memory T cells","volume":"382","author":"Park","year":"2023","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0130","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.mucimm.2022.11.004","article-title":"Tissue-resident memory T cells trigger rapid exudation and local antibody accumulation","volume":"16","author":"Rosato","year":"2023","journal-title":"Mucosal Immunol"},{"issue":"96","key":"10.1016\/j.autrev.2025.103977_bb0135","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.adj8356","article-title":"Circulating KLRG1+ long-lived effector memory T cells retain the flexibility to become tissue resident","volume":"9","author":"Lucas","year":"2024","journal-title":"Sci Immunol"},{"issue":"34","key":"10.1016\/j.autrev.2025.103977_bb0140","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2219932120","article-title":"Cross-presenting Langerhans cells are required for the early reactivation of resident CD8+ memory T cells in the epidermis","volume":"120","author":"Kamenjarin","year":"2023","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0145","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1146\/annurev-immunol-101320-020220","article-title":"The multifaceted role of tissue-resident memory T cells","volume":"42","author":"Christo","year":"2024","journal-title":"Annu Rev Immunol"},{"issue":"6","key":"10.1016\/j.autrev.2025.103977_bb0150","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1053\/j.gastro.2023.10.022","article-title":"Tertiary lymphoid structure-associated B cells enhance CXCL13+CD103+CD8+ tissue-resident memory T-cell response to programmed cell death protein 1 blockade in Cancer immunotherapy","volume":"166","author":"Hu","year":"2024","journal-title":"Gastroenterology"},{"issue":"6","key":"10.1016\/j.autrev.2025.103977_bb0155","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20200940","article-title":"Ptpn2 and KLRG1 regulate the generation and function of tissue-resident memory CD8+ T cells in skin","volume":"218","author":"Hochheiser","year":"2021","journal-title":"J Exp Med"},{"key":"10.1016\/j.autrev.2025.103977_bb0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2022.102811","article-title":"Skin CD4+ Trm cells distinguish acute cutaneous lupus erythematosus from localized discoid lupus erythematosus\/subacute cutaneous lupus erythematosus and other skin diseases","volume":"128","author":"Zhao","year":"2022","journal-title":"J Autoimmun"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0165","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1038\/s41392-023-01471-y","article-title":"T cells in health and disease","volume":"8","author":"Sun","year":"2023","journal-title":"Signal Transduct Target Ther"},{"issue":"12","key":"10.1016\/j.autrev.2025.103977_bb0170","first-page":"875","article-title":"Cytotoxic CD4+ tissue-resident memory T cells are associated with asthma severity","volume":"4","author":"Herrera-De La Mata","year":"2023","journal-title":"Med N Y N"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0175","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2204269120","article-title":"Identification of a unique subset of tissue-resident memory CD4+ T cells in Crohn\u2019s disease","volume":"120","author":"Yokoi","year":"2023","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"36","key":"10.1016\/j.autrev.2025.103977_bb0180","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.adg3469","article-title":"Single-cycle influenza virus vaccine generates lung CD8+ Trm that cross-react against viral variants and subvert virus escape mutants","volume":"9","author":"Zheng","year":"2023","journal-title":"Sci Adv"},{"issue":"6","key":"10.1016\/j.autrev.2025.103977_bb0185","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1016\/j.jaci.2020.01.042","article-title":"Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis","volume":"145","author":"He","year":"2020","journal-title":"J Allergy Clin Immunol"},{"issue":"2","key":"10.1016\/j.autrev.2025.103977_bb0190","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1038\/s41590-022-01395-9","article-title":"Tissue adaptation and clonal segregation of human memory T cells in barrier sites","volume":"24","author":"Poon","year":"2023","journal-title":"Nat Immunol"},{"issue":"10","key":"10.1016\/j.autrev.2025.103977_bb0195","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1136\/ard-2023-225069","article-title":"CD8+ tissue-resident memory T cells are expanded in primary Sj\u00f6gren\u2019s disease and can be therapeutically targeted by CD103 blockade","volume":"83","author":"Mauro","year":"2024","journal-title":"Ann Rheum Dis"},{"issue":"3","key":"10.1016\/j.autrev.2025.103977_bb0200","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.108661","article-title":"Human intestinal tissue-resident memory T cells comprise transcriptionally and functionally distinct subsets","volume":"34","author":"FitzPatrick","year":"2021","journal-title":"Cell Rep"},{"issue":"8","key":"10.1016\/j.autrev.2025.103977_bb0205","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1016\/j.immuni.2024.06.005","article-title":"Primary nasal influenza infection rewires tissue-scale memory response dynamics","volume":"57","author":"Kazer","year":"2024","journal-title":"Immunity"},{"issue":"3","key":"10.1016\/j.autrev.2025.103977_bb0210","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20231144","article-title":"Regenerating murine CD8+ lung tissue resident memory T cells after targeted radiation exposure","volume":"221","author":"Hassert","year":"2024","journal-title":"J Exp Med"},{"key":"10.1016\/j.autrev.2025.103977_bb0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2024.111924","article-title":"CIRP increases Foxp3+ regulatory T cells and inhibits development of Th17 cells by enhancing TLR4-IL-2 signaling in the late phase of sepsis","volume":"132","author":"Wu","year":"2024","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.autrev.2025.103977_bb0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2020.107295","article-title":"HMGB1 suppress the expression of IL-35 by regulating na\u00efve CD4+ T cell differentiation and aggravating Caspase-11-dependent pyroptosis in acute lung injury","volume":"91","author":"Xie","year":"2021","journal-title":"Int Immunopharmacol"},{"issue":"10","key":"10.1016\/j.autrev.2025.103977_bb0225","doi-asserted-by":"crossref","first-page":"2763","DOI":"10.3390\/cells10102763","article-title":"The role of epithelial damage in the pulmonary immune response","volume":"10","author":"Burgoyne","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.autrev.2025.103977_bb0230","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.611910","article-title":"Untangling local pro-inflammatory, reparative, and regulatory damage-associated molecular-patterns (DAMPs) pathways to improve transplant outcomes","volume":"12","author":"Dwyer","year":"2021","journal-title":"Front Immunol"},{"issue":"4","key":"10.1016\/j.autrev.2025.103977_bb0235","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1002\/path.5473","article-title":"Spontaneous onset of TNF\u03b1-triggered colonic inflammation depends on functional T lymphocytes, S100A8\/A9 alarmins, and MHC H-2 haplotype","volume":"251","author":"Leite Dantas","year":"2020","journal-title":"J Pathol"},{"issue":"7933","key":"10.1016\/j.autrev.2025.103977_bb0240","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1038\/s41586-022-05309-5","article-title":"Novel antigen-presenting cell imparts Treg-dependent tolerance to gut microbiota","volume":"610","author":"Akagbosu","year":"2022","journal-title":"Nature"},{"issue":"12","key":"10.1016\/j.autrev.2025.103977_bb0245","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.1002\/eji.202048741","article-title":"NK1.1+ innate lymphoid cells in salivary glands inhibit establishment of tissue-resident memory CD8+ T cells in mice","volume":"50","author":"Woyciechowski","year":"2020","journal-title":"Eur J Immunol"},{"issue":"4","key":"10.1016\/j.autrev.2025.103977_bb0250","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.184048","article-title":"NKG2D blockade impairs tissue-resident memory T cell accumulation and reduces chronic lung allograft dysfunction","volume":"10","author":"Moghbeli","year":"2025","journal-title":"JCI Insight"},{"issue":"9","key":"10.1016\/j.autrev.2025.103977_bb0255","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1038\/s41423-024-01197-z","article-title":"Tissue-resident memory T cells break tolerance to renal autoantigens and orchestrate immune-mediated nephritis","volume":"21","author":"Arnold","year":"2024","journal-title":"Cell Mol Immunol"},{"key":"10.1016\/j.autrev.2025.103977_bb0260","doi-asserted-by":"crossref","first-page":"2811","DOI":"10.3389\/fimmu.2018.02811","article-title":"A novel approach of identifying Immunodominant self and viral antigen cross-reactive T cells and defining the epitopes they recognize","volume":"9","author":"Yang","year":"2018","journal-title":"Front Immunol"},{"issue":"5","key":"10.1016\/j.autrev.2025.103977_bb0265","doi-asserted-by":"crossref","DOI":"10.1002\/eji.202350413","article-title":"Bystander activation of tissue-resident memory CD4 T cells: getting by with a little help from unfamiliar T-cell friends","volume":"53","author":"Cornelis","year":"2023","journal-title":"Eur J Immunol"},{"issue":"8","key":"10.1016\/j.autrev.2025.103977_bb0270","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20192291","article-title":"Tissue-resident memory T cell reactivation by diverse antigen-presenting cells imparts distinct functional responses","volume":"217","author":"Low","year":"2020","journal-title":"J Exp Med"},{"issue":"10","key":"10.1016\/j.autrev.2025.103977_bb0275","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20191711","article-title":"A committed tissue-resident memory T cell precursor within the circulating CD8+ effector T cell pool","volume":"217","author":"Kok","year":"2020","journal-title":"J Exp Med"},{"issue":"3","key":"10.1016\/j.autrev.2025.103977_bb0280","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1011165","article-title":"Berberine governs NOTCH3\/AKT signaling to enrich lung-resident memory T cells during tuberculosis","volume":"19","author":"Pahuja","year":"2023","journal-title":"PLoS Pathog"},{"issue":"3","key":"10.1016\/j.autrev.2025.103977_bb0285","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.jaci.2016.11.045","article-title":"Recognition of viral and self-antigens by TH1 and TH1\/TH17 central memory cells in patients with multiple sclerosis reveals distinct roles in immune surveillance and relapses","volume":"140","author":"Paroni","year":"2017","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.autrev.2025.103977_bb0290","article-title":"Resident memory T cells in dirty mice suppress innate cell activation and infiltration into the skin following stimulation with alarmins","author":"Story","year":"2024","journal-title":"BioRxiv Prepr Serv Biol"},{"issue":"12","key":"10.1016\/j.autrev.2025.103977_bb0295","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1038\/s41590-020-0791-5","article-title":"Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans","volume":"21","author":"Galletti","year":"2020","journal-title":"Nat Immunol"},{"issue":"6","key":"10.1016\/j.autrev.2025.103977_bb0300","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2024.114258","article-title":"T-bet deficiency and Hic1 induction override TGF-\u03b2-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells","volume":"43","author":"Wang","year":"2024","journal-title":"Cell Rep"},{"issue":"82","key":"10.1016\/j.autrev.2025.103977_bb0305","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.add8454","article-title":"Tissue-resident memory T cell maintenance during antigen persistence requires both cognate antigen and interleukin-15","volume":"8","author":"Tieu","year":"2023","journal-title":"Sci Immunol."},{"key":"10.1016\/j.autrev.2025.103977_bb0310","article-title":"Neutrophil recruitment by CD4 tissue-resident memory T cells induces chronic recurrent inflammation in atopic dermatitis","volume":"256","author":"Zheng","year":"2023","journal-title":"Clin Immunol Orlando Fla"},{"issue":"8","key":"10.1016\/j.autrev.2025.103977_bb0315","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20192197","article-title":"Retrograde migration supplies resident memory T cells to lung-draining LN after influenza infection","volume":"217","author":"Stolley","year":"2020","journal-title":"J Exp Med"},{"issue":"37","key":"10.1016\/j.autrev.2025.103977_bb0320","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.aav8995","article-title":"Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy individuals","volume":"4","author":"Klicznik","year":"2019","journal-title":"Sci Immunol."},{"issue":"9\u201310","key":"10.1016\/j.autrev.2025.103977_bb0325","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1007\/s10495-024-01970-5","article-title":"IRG1\/Itaconate inhibits proliferation and promotes apoptosis of CD69+CD103+CD8+ tissue-resident memory T cells in autoimmune hepatitis by regulating the JAK3\/STAT3\/P53 signalling pathway","volume":"29","author":"Zhou","year":"2024","journal-title":"Apoptosis Int J Program Cell Death"},{"key":"10.1016\/j.autrev.2025.103977_bb0330","article-title":"Targeting chronic COVID-19 lung injury; Tofacitinib can be used against tissue-resident memory T cells","volume":"147","author":"Zununi Vahed","year":"2022","journal-title":"Biomed Pharmacother Biomedecine Pharmacother"},{"issue":"11","key":"10.1016\/j.autrev.2025.103977_bb0335","doi-asserted-by":"crossref","first-page":"2737","DOI":"10.3390\/microorganisms11112737","article-title":"Memory T cells discrepancies in COVID-19 patients","volume":"11","author":"Al Saihati","year":"2023","journal-title":"Microorganisms"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0340","doi-asserted-by":"crossref","first-page":"3010","DOI":"10.1038\/s41467-021-23333-3","article-title":"Peripheral and lung resident memory T cell responses against SARS-CoV-2","volume":"12","author":"Grau-Exp\u00f3sito","year":"2021","journal-title":"Nat Commun"},{"issue":"12","key":"10.1016\/j.autrev.2025.103977_bb0345","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1038\/s41423-022-00940-8","article-title":"The epidermal immune microenvironment plays a dominant role in psoriasis development, as revealed by mass cytometry","volume":"19","author":"Zhou","year":"2022","journal-title":"Cell Mol Immunol"},{"issue":"77","key":"10.1016\/j.autrev.2025.103977_bb0350","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.abq3254","article-title":"Local IL-23 is required for proliferation and retention of skin-resident memory TH17 cells","volume":"7","author":"Whitley","year":"2022","journal-title":"Sci Immunol."},{"issue":"4","key":"10.1016\/j.autrev.2025.103977_bb0355","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/j.jid.2018.10.032","article-title":"Resident memory and recirculating memory T cells cooperate to maintain disease in a mouse model of vitiligo","volume":"139","author":"Richmond","year":"2019","journal-title":"J Invest Dermatol"},{"issue":"9","key":"10.1016\/j.autrev.2025.103977_bb0360","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.111308","article-title":"Enterobacter ludwigii protects DSS-induced colitis through choline-mediated immune tolerance","volume":"40","author":"Li","year":"2022","journal-title":"Cell Rep"},{"issue":"7","key":"10.1016\/j.autrev.2025.103977_bb0365","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1038\/s41590-020-0674-9","article-title":"Type 1 Treg cells promote the generation of CD8+ tissue-resident memory T cells","volume":"21","author":"Ferreira","year":"2020","journal-title":"Nat Immunol"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0370","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1007\/s10565-024-09892-3","article-title":"PD-L2 mediates tobacco smoking-induced recruitment of regulatory T cells via the RGMB\/NF\u03baB\/CCL20 cascade","volume":"40","author":"Guo","year":"2024","journal-title":"Cell Biol Toxicol"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0375","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1038\/s41467-023-36747-y","article-title":"Inhibition of ALKBH5 attenuates I\/R-induced renal injury in male mice by promoting Ccl28 m6A modification and increasing Treg recruitment","volume":"14","author":"Chen","year":"2023","journal-title":"Nat Commun"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0380","first-page":"27","article-title":"Stereotypic expansion of T regulatory and Th17 cells during infancy is disrupted by HIV exposure and gut epithelial damage","volume":"208","author":"Dzanibe","year":"2022","journal-title":"J Immunol Baltim Md 1950"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0385","doi-asserted-by":"crossref","first-page":"9143","DOI":"10.1038\/s41467-024-53112-9","article-title":"Dominant immune tolerance in the intestinal tract imposed by RelB-dependent migratory dendritic cells regulates protective type 2 immunity","volume":"15","author":"Geiselh\u00f6ringer","year":"2024","journal-title":"Nat Commun"},{"key":"10.1016\/j.autrev.2025.103977_bb0390","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.984476","article-title":"PD-1 and ICOS counter-regulate tissue resident regulatory T cell development and IL-10 production during flu","volume":"13","author":"McGee","year":"2022","journal-title":"Front Immunol"},{"issue":"83","key":"10.1016\/j.autrev.2025.103977_bb0395","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.abn4332","article-title":"Tissue-resident memory T cells mediate mucosal immunity to recurrent urinary tract infection","volume":"8","author":"Rousseau","year":"2023","journal-title":"Sci Immunol"},{"issue":"3","key":"10.1016\/j.autrev.2025.103977_bb0400","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2025.115294","article-title":"Lung CD4+ resident memory T cells use airway secretory cells to stimulate and regulate onset of allergic airway neutrophilic disease","volume":"44","author":"Ravi","year":"2025","journal-title":"Cell Rep"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0405","doi-asserted-by":"crossref","first-page":"8355","DOI":"10.1038\/s41467-024-52689-5","article-title":"SARS-CoV-2 spike-specific nasal-resident CD49a+CD8+ memory T cells exert immediate effector functions with enhanced IFN-\u03b3 production","volume":"15","author":"Rha","year":"2024","journal-title":"Nat Commun"},{"issue":"7","key":"10.1016\/j.autrev.2025.103977_bb0410","first-page":"2451","article-title":"Chemokine receptor-dependent control of skin tissue-resident memory T cell formation","volume":"199","author":"Zaid","year":"2017","journal-title":"J Immunol Baltim Md 1950"},{"issue":"11","key":"10.1016\/j.autrev.2025.103977_bb0415","doi-asserted-by":"crossref","DOI":"10.1002\/cti2.1214","article-title":"Human-engineered Treg-like cells suppress FOXP3-deficient T cells but preserve adaptive immune responses in vivo","volume":"9","author":"Sato","year":"2020","journal-title":"Clin Transl Immunol"},{"key":"10.1016\/j.autrev.2025.103977_bb0420","article-title":"Modulation of antigen-specific CD8 T cell responses by the skin commensal staphylococcus epidermidis","author":"Nerb","year":"2025","journal-title":"phd"},{"issue":"12","key":"10.1016\/j.autrev.2025.103977_bb0425","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20230558","article-title":"Regulatory T cells control Staphylococcus aureus and disease severity of cutaneous leishmaniasis","volume":"220","author":"Singh","year":"2023","journal-title":"J Exp Med"},{"issue":"6","key":"10.1016\/j.autrev.2025.103977_bb0430","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1016\/j.immuni.2023.03.008","article-title":"Long-term tolerance to skin commensals is established neonatally through a specialized dendritic cell subgroup","volume":"56","author":"Weckel","year":"2023","journal-title":"Immunity"},{"issue":"8","key":"10.1016\/j.autrev.2025.103977_bb0435","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1038\/s41590-025-02228-1","article-title":"PD-1 is requisite for skin TRM cell formation and specification by TGF\u03b2","volume":"26","author":"Devi","year":"2025","journal-title":"Nat Immunol"},{"key":"10.1016\/j.autrev.2025.103977_bb0440","article-title":"Pathophysiology of skin resident memory T cells","volume":"11","author":"Tokura","year":"2020","journal-title":"Front Immunol"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0445","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1001\/jamaoncol.2021.4318","article-title":"Management of Cutaneous Immune-Related Adverse Events in patients with Cancer treated with immune checkpoint inhibitors: a systematic review","volume":"8","author":"Nadelmann","year":"2022","journal-title":"JAMA Oncol"},{"issue":"8","key":"10.1016\/j.autrev.2025.103977_bb0450","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1038\/s41590-025-02207-6","article-title":"IL-4 impairs the formation of skin-resident memory CD8+ T cells","volume":"26","author":"Mora-Buch","year":"2025","journal-title":"Nat Immunol"},{"key":"10.1016\/j.autrev.2025.103977_bb0455","first-page":"14","article-title":"Intestinal factors promoting the development of ROR\u03b3t+ cells and oral tolerance","author":"L\u00f3pez-Fandi\u00f1o","year":"2023","journal-title":"Front Immunol"},{"issue":"10","key":"10.1016\/j.autrev.2025.103977_bb0460","doi-asserted-by":"crossref","first-page":"2269","DOI":"10.1016\/j.immuni.2024.09.011","article-title":"Antigen-presenting cells as specialized drivers of intestinal T cell functions","volume":"57","author":"Kedmi","year":"2024","journal-title":"Immunity"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0465","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1186\/s12964-024-01505-0","article-title":"The dynamic shifts of IL-10-producing Th17 and IL-17-producing Treg in health and disease: a crosstalk between ancient \u201cyin-Yang\u201d theory and modern immunology","volume":"22","author":"Cui","year":"2024","journal-title":"Cell Commun Signal"},{"key":"10.1016\/j.autrev.2025.103977_bb0470","first-page":"13","article-title":"Intraperitoneally delivered mesenchymal stem cells alleviate experimental colitis through THBS1-mediated induction of IL-10-competent regulatory B cells","author":"Liu","year":"2022","journal-title":"Front Immunol"},{"issue":"6","key":"10.1016\/j.autrev.2025.103977_bb0475","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1093\/ecco-jcc\/jjz176","article-title":"Deletion of IL-6 exacerbates colitis and induces systemic inflammation in IL-10-deficient mice","volume":"14","author":"Ye","year":"2020","journal-title":"J Crohns Colitis"},{"key":"10.1016\/j.autrev.2025.103977_bb0480","series-title":"A Cross-Talk Between Microbiota-Derived Short-Chain Fatty Acids and the Host Mucosal Immune System Regulates Intestinal Homeostasis and Inflammatory Bowel Disease","author":"Gon\u00e7alves","year":"2025"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0485","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1007\/s11033-025-10714-w","article-title":"Role of the intestinal flora-immunity axis in the pathogenesis of rheumatoid arthritis-mechanisms regulating short-chain fatty acids and Th17\/Treg homeostasis","volume":"52","author":"Lv","year":"2025","journal-title":"Mol Biol Rep"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0490","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41467-021-26045-w","article-title":"Antigen presentation by lung epithelial cells directs CD4+ TRM cell function and regulates barrier immunity","volume":"12","author":"Shenoy","year":"2021","journal-title":"Nat Commun"},{"issue":"21","key":"10.1016\/j.autrev.2025.103977_bb0495","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.140384","article-title":"IRF4 expression by lung dendritic cells drives acute but not Trm cell\u2013dependent memory Th2 responses","volume":"7","author":"Camacho","year":"2025","journal-title":"JCI Insight"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0500","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1111\/imr.13201","article-title":"Tissue-resident memory T cells and lung immunopathology","volume":"316","author":"Cheon","year":"2023","journal-title":"Immunol Rev"},{"issue":"4","key":"10.1016\/j.autrev.2025.103977_bb0505","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1111\/all.15144","article-title":"CD103 integrin identifies a high IL-10-producing FoxP3+ regulatory T-cell population suppressing allergic airway inflammation","volume":"77","author":"Tagkareli","year":"2022","journal-title":"Allergy"},{"issue":"8","key":"10.1016\/j.autrev.2025.103977_bb0510","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1007\/s11427-024-2920-y","article-title":"CCR5-mediated dynamic maintenance of resident memory T cells in the respiratory tract","volume":"68","author":"Shao","year":"2025","journal-title":"Sci China Life Sci"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0515","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1038\/s44298-024-00073-x","article-title":"Modulating cytokine microenvironment during T cell activation induces protective RSV-specific lung resident memory T cells in early life in mice","volume":"2","author":"Wang","year":"2024","journal-title":"NPJ Viruses"},{"issue":"8","key":"10.1016\/j.autrev.2025.103977_bb0520","first-page":"1025","article-title":"Influenza-induced CD11alo airway CD103+ TRM cells exhibit compromised IFN-\u03b3 production after in vivo TCR-stimulation","volume":"210","author":"van de Wall","year":"2023","journal-title":"J Immunol Baltim Md 1950"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0525","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/s12967-023-04839-4","article-title":"Spatial features of specific CD103+CD8+ tissue-resident memory T cell subsets define the prognosis in patients with non-small cell lung cancer","volume":"22","author":"Yang","year":"2024","journal-title":"J Transl Med"},{"issue":"28","key":"10.1016\/j.autrev.2025.103977_bb0530","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202503557","article-title":"CD103+ T cells eliminate damaged alveolar epithelial type II cells under oxidative stress to prevent lung tumorigenesis","volume":"12","author":"Xu","year":"2025","journal-title":"Adv Sci"},{"issue":"3","key":"10.1016\/j.autrev.2025.103977_bb0535","doi-asserted-by":"crossref","first-page":"2696","DOI":"10.3390\/ijms24032696","article-title":"CD4 T-cell subsets and the pathophysiology of inflammatory bowel disease","volume":"24","author":"Gomez-Bris","year":"2023","journal-title":"Int J Mol Sci"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0540","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.immuni.2020.10.022","article-title":"Competition for active TGF\u03b2 cytokine allows for selective retention of antigen-specific tissue- resident memory T cells in the epidermal niche","volume":"54","author":"Hirai","year":"2021","journal-title":"Immunity"},{"issue":"7","key":"10.1016\/j.autrev.2025.103977_bb0545","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20212391","article-title":"Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits","volume":"219","author":"Whyte","year":"2022","journal-title":"J Exp Med"},{"key":"10.1016\/j.autrev.2025.103977_bb0550","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellimm.2023.104664","article-title":"Soluble CD25 imposes a low-zone IL-2 signaling environment that favors competitive outgrowth of antigen-experienced CD25high regulatory and memory T cells","volume":"384","author":"Nickle","year":"2023","journal-title":"Cell Immunol"},{"issue":"3","key":"10.1016\/j.autrev.2025.103977_bb0555","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.182615","article-title":"Airway-resident memory CD4 T cell activation accelerates antigen presentation and T cell priming in draining lymph nodes","volume":"10","author":"Finn","year":"2024","journal-title":"JCI Insight"},{"issue":"6739","key":"10.1016\/j.autrev.2025.103977_bb0560","doi-asserted-by":"crossref","DOI":"10.1126\/science.ado5088","article-title":"Identification of antigen-presenting cell-T cell interactions driving immune responses to food","volume":"387","author":"Campos Canesso","year":"2025","journal-title":"Science"},{"issue":"4","key":"10.1016\/j.autrev.2025.103977_bb0565","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1093\/ecco-jcc\/jjz175","article-title":"Deficient resident memory T cell and CD8 T cell response to commensals in inflammatory bowel disease","volume":"14","author":"Noble","year":"2020","journal-title":"J Crohns Colitis"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0570","doi-asserted-by":"crossref","first-page":"10898","DOI":"10.1038\/s41598-023-36884-w","article-title":"Transient regulatory-T-cell interruption promotes skin-resident memory T cells mediated tumor protection","volume":"13","author":"Zhao","year":"2023","journal-title":"Sci Rep"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0575","doi-asserted-by":"crossref","first-page":"5579","DOI":"10.1038\/s41467-023-41364-w","article-title":"CD8+ tissue-resident memory T-cell development depends on infection-matching regulatory T-cell types","volume":"14","author":"Barros","year":"2023","journal-title":"Nat Commun"},{"issue":"7","key":"10.1016\/j.autrev.2025.103977_bb0580","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1038\/s41590-020-0674-9","article-title":"Type 1 Treg cells promote the generation of CD8+ tissue-resident memory T cells","volume":"21","author":"Ferreira","year":"2020","journal-title":"Nat Immunol"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0585","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1186\/s12964-025-02134-x","article-title":"PLZF-expressing CD4+ T cells promote tissue-resident memory T cells in breaking immune tolerance in allergic asthma via IL-15\/IL-15R\u03b1 signaling","volume":"23","author":"Zhang","year":"2025","journal-title":"Cell Commun Signal"},{"issue":"20","key":"10.1016\/j.autrev.2025.103977_bb0590","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.136206","article-title":"IL-4R\u03b1 signaling in CD4+CD25+FoxP3+ T regulatory cells restrains airway inflammation via limiting local tissue IL-33","volume":"5","author":"Khumalo","year":"2025","journal-title":"JCI Insight"},{"issue":"7","key":"10.1016\/j.autrev.2025.103977_bb0595","doi-asserted-by":"crossref","DOI":"10.1172\/JCI155880","article-title":"Corticosteroids impair epithelial regeneration in immune-mediated intestinal damage","volume":"134","author":"Arnhold","year":"2024","journal-title":"J Clin Invest"},{"key":"10.1016\/j.autrev.2025.103977_bb0600","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1146\/annurev-immunol-101721-062818","article-title":"Immune-epithelial cross talk in regeneration and repair","volume":"41","author":"Guenin-Mace","year":"2023","journal-title":"Annu Rev Immunol"},{"issue":"4","key":"10.1016\/j.autrev.2025.103977_bb0605","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1038\/s41418-020-00650-6","article-title":"IL-24 deficiency protects mice against bleomycin-induced pulmonary fibrosis by repressing IL-4-induced M2 program in macrophages","volume":"28","author":"Rao","year":"2021","journal-title":"Cell Death Differ"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0610","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1186\/s12967-021-02890-7","article-title":"Interleukin-24 regulates mucosal remodeling in inflammatory bowel diseases","volume":"19","author":"\u00d3nody","year":"2021","journal-title":"J Transl Med"},{"issue":"5","key":"10.1016\/j.autrev.2025.103977_bb0615","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1111\/all.16479","article-title":"Roles of Interleukin-24 in epithelial repair: bridging injury and regeneration","volume":"80","author":"Bryant","year":"2025","journal-title":"Allergy"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0620","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1038\/s41392-024-02050-5","article-title":"Tissue-resident immune cells: from defining characteristics to roles in diseases","volume":"10","author":"Li","year":"2025","journal-title":"Signal Transduct Target Ther"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0625","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1186\/s12931-022-02167-7","article-title":"IL-37 protects against airway remodeling by reversing bronchial epithelial\u2013mesenchymal transition via IL-24 signaling pathway in chronic asthma","volume":"23","author":"Feng","year":"2022","journal-title":"Respir Res"},{"key":"10.1016\/j.autrev.2025.103977_bb0630","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2024.113972","article-title":"House dust mite induced mucosal barrier dysfunction and type 2 inflammatory responses via the MAPK\/AP-1\/IL-24 signaling pathway in allergic rhinitis","volume":"148","author":"Zhang","year":"2025","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.autrev.2025.103977_bb0635","first-page":"12","article-title":"Interleukin-17A drives IL-19 and IL-24 expression in skin stromal cells regulating keratinocyte proliferation","author":"Xu","year":"2021","journal-title":"Front Immunol"},{"issue":"5","key":"10.1016\/j.autrev.2025.103977_bb0640","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1111\/omi.12265","article-title":"Regulation of IL-24 in human oral keratinocytes stimulated with Tannerella forsythia","volume":"34","author":"Ko","year":"2019","journal-title":"Mol Oral Microbiol"},{"issue":"5","key":"10.1016\/j.autrev.2025.103977_bb0645","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/j.immuni.2024.04.003","article-title":"CD80 on skin stem cells promotes local expansion of regulatory T cells upon injury to orchestrate repair within an inflammatory environment","volume":"57","author":"Luan","year":"2024","journal-title":"Immunity"},{"issue":"11","key":"10.1016\/j.autrev.2025.103977_bb0650","doi-asserted-by":"crossref","first-page":"1922","DOI":"10.1016\/j.stem.2021.08.007","article-title":"Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis","volume":"28","author":"Beyaz","year":"2021","journal-title":"Cell Stem Cell"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0655","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1111\/imr.13210","article-title":"Axes of heterogeneity in human tissue-resident memory T cells","volume":"316","author":"Szabo","year":"2023","journal-title":"Immunol Rev"},{"key":"10.1016\/j.autrev.2025.103977_bb0660","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2024.103206","article-title":"Characterization of Th17 tissue-resident memory cells in non-inflamed intestinal tissue of Crohn\u2019s disease patients","volume":"145","author":"Lee","year":"2024","journal-title":"J Autoimmun"},{"issue":"91","key":"10.1016\/j.autrev.2025.103977_bb0665","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.adh0152","article-title":"Regulatory T cells in skin mediate immune privilege of the hair follicle stem cell niche","volume":"9","author":"Cohen","year":"2024","journal-title":"Sci Immunol"},{"issue":"21","key":"10.1016\/j.autrev.2025.103977_bb0670","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.149656","article-title":"The small intestine epithelium exempts Foxp3+ Tregs from their IL-2 requirement for homeostasis and effector function","volume":"6","author":"Prakhar","year":"2021","journal-title":"JCI Insight"},{"issue":"9","key":"10.1016\/j.autrev.2025.103977_bb0675","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.1016\/j.jid.2021.02.748","article-title":"Highly multiplexed mass cytometry identifies the Immunophenotype in the skin of dermatomyositis","volume":"141","author":"Patel","year":"2021","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.autrev.2025.103977_bb0680","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2024.103206","article-title":"Characterization of Th17 tissue-resident memory cells in non-inflamed intestinal tissue of Crohn\u2019s disease patients","volume":"145","author":"Lee","year":"2024","journal-title":"J Autoimmun"},{"issue":"6","key":"10.1016\/j.autrev.2025.103977_bb0685","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1016\/j.cmet.2016.12.018","article-title":"Foxp3 reprograms T cell metabolism to function in Low-glucose, High-Lactate Environments","volume":"25","author":"Angelin","year":"2017","journal-title":"Cell Metab"},{"issue":"2","key":"10.1016\/j.autrev.2025.103977_bb0690","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1038\/s41590-020-00834-9","article-title":"Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion","volume":"22","author":"Scharping","year":"2021","journal-title":"Nat Immunol"},{"issue":"20","key":"10.1016\/j.autrev.2025.103977_bb0695","first-page":"1619","article-title":"High-fructose corn syrup aggravates colitis via microbiota dysbiosis-mediated Th17\/Treg imbalance","volume":"137","author":"Zhou","year":"2023","journal-title":"Clin Sci Lond Engl 1979"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0700","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.immuni.2019.12.007","article-title":"Regulatory T cells restrain Interleukin-2- and Blimp-1-dependent Acquisition of Cytotoxic Function by CD4+ T cells","volume":"52","author":"\u015aledzi\u0144ska","year":"2020","journal-title":"Immunity"},{"issue":"13","key":"10.1016\/j.autrev.2025.103977_bb0705","doi-asserted-by":"crossref","first-page":"4056","DOI":"10.1073\/pnas.1418549112","article-title":"T-bet- and STAT4-dependent IL-33 receptor expression directly promotes antiviral Th1 cell responses","volume":"112","author":"Baumann","year":"2015","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.autrev.2025.103977_bb0710","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.3389\/fimmu.2020.01111","article-title":"Lower T regulatory and Th17 cell populations predicted by RT-PCR-amplified FOXP3 and ROR\u03b3t genes are not rare in patients with primary immunodeficiency diseases","volume":"11","author":"Lee","year":"2020","journal-title":"Front Immunol"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0715","doi-asserted-by":"crossref","DOI":"10.1002\/mco2.70053","article-title":"Tissue-resident memory T cells in diseases and therapeutic strategies","volume":"6","author":"Xie","year":"2025","journal-title":"MedComm"},{"issue":"30","key":"10.1016\/j.autrev.2025.103977_bb0720","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2023739118","article-title":"Treg-expressed CTLA-4 depletes CD80\/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells","volume":"118","author":"Tekguc","year":"2021","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.autrev.2025.103977_bb0725","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.997376","article-title":"PD-1 and CTLA-4 exert additive control of effector regulatory T cells at homeostasis","volume":"14","author":"Pereira","year":"2023","journal-title":"Front Immunol"},{"issue":"6","key":"10.1016\/j.autrev.2025.103977_bb0730","doi-asserted-by":"crossref","DOI":"10.1111\/hel.12763","article-title":"Dendritic cell-derived TGF-\u03b2 mediates the induction of mucosal regulatory T-cell response to Helicobacter infection essential for maintenance of immune tolerance in mice","volume":"25","author":"Owyang","year":"2020","journal-title":"Helicobacter"},{"issue":"5","key":"10.1016\/j.autrev.2025.103977_bb0735","doi-asserted-by":"crossref","DOI":"10.1002\/eji.202350839","article-title":"Retinoic acid-loaded liposomes induce human mucosal CD103+ dendritic cells that inhibit Th17 cells and drive regulatory T-cell development in vitro","volume":"54","author":"Nagy","year":"2024","journal-title":"Eur J Immunol"},{"issue":"3","key":"10.1016\/j.autrev.2025.103977_bb0740","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1093\/rheumatology\/kead273","article-title":"Increased CD8+ tissue resident memory T cells, regulatory T cells and activated natural killer cells in systemic sclerosis lungs","volume":"63","author":"Padilla","year":"2024","journal-title":"Rheumatol Oxf Engl"},{"key":"10.1016\/j.autrev.2025.103977_bb0745","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2023.115979","article-title":"Methotrexate and electrostimulation cooperate to alleviate the relapse of psoriasiform skin inflammation by suppressing memory T cells","volume":"219","author":"Chen","year":"2024","journal-title":"Biochem Pharmacol"},{"issue":"5","key":"10.1016\/j.autrev.2025.103977_bb0750","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2023.112514","article-title":"Psoriatic and rheumatoid arthritis joints differ in the composition of CD8+ tissue-resident memory T cell subsets","volume":"42","author":"Povoleri","year":"2023","journal-title":"Cell Rep"},{"key":"10.1016\/j.autrev.2025.103977_bb0755","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1016\/j.biopha.2017.06.055","article-title":"MiR-200a expression in CD4+ T cells correlates with the expression of Th17\/Treg cells and relevant cytokines in psoriasis vulgaris: a case control study","volume":"93","author":"Wang","year":"2017","journal-title":"Biomed Pharmacother Biomedecine Pharmacother"},{"key":"10.1016\/j.autrev.2025.103977_bb0760","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.3389\/fimmu.2019.01865","article-title":"IL-21 induces an imbalance of Th17\/Treg cells in moderate-to-severe plaque psoriasis patients","volume":"10","author":"Shi","year":"2019","journal-title":"Front Immunol"},{"issue":"10","key":"10.1016\/j.autrev.2025.103977_bb0765","doi-asserted-by":"crossref","first-page":"2098","DOI":"10.1016\/j.jid.2018.12.035","article-title":"Dysregulation of Akt-FOXO1 pathway leads to dysfunction of regulatory T cells in patients with psoriasis","volume":"139","author":"Li","year":"2019","journal-title":"J Invest Dermatol"},{"issue":"3","key":"10.1016\/j.autrev.2025.103977_bb0770","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.jaci.2023.05.012","article-title":"Single-cell transcriptomics suggest distinct upstream drivers of IL-17A\/F in hidradenitis versus psoriasis","volume":"152","author":"Kim","year":"2023","journal-title":"J Allergy Clin Immunol"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0775","doi-asserted-by":"crossref","first-page":"2345","DOI":"10.1038\/s41467-024-45870-3","article-title":"IKK2 controls the inflammatory potential of tissue-resident regulatory T cells in a murine gain of function model","volume":"15","author":"Cardinez","year":"2024","journal-title":"Nat Commun"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0780","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.immuni.2022.12.007","article-title":"Small intestine and colon tissue-resident memory CD8+ T cells exhibit molecular heterogeneity and differential dependence on Eomes","volume":"56","author":"Lin","year":"2023","journal-title":"Immunity"},{"issue":"4","key":"10.1016\/j.autrev.2025.103977_bb0785","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1053\/j.gastro.2021.06.025","article-title":"Interferon-gamma-producing CD8+ tissue resident memory T cells are a targetable Hallmark of immune checkpoint inhibitor-colitis","volume":"161","author":"Sasson","year":"2021","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0790","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2023.2190304","article-title":"Lactobacillus rhamnosus GG ameliorates osteoporosis in ovariectomized rats by regulating the Th17\/Treg balance and gut microbiota structure","volume":"15","author":"Guo","year":"2023","journal-title":"Gut Microbes"},{"issue":"3","key":"10.1016\/j.autrev.2025.103977_bb0795","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1038\/s41590-024-02075-6","article-title":"Terminal differentiation and persistence of effector regulatory Tcells essential for preventing intestinal inflammation","volume":"26","author":"Dikiy","year":"2025","journal-title":"Nat Immunol"},{"issue":"11","key":"10.1016\/j.autrev.2025.103977_bb0800","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20210777","article-title":"Arkadia-SKI\/SnoN signaling differentially regulates TGF-\u03b2-induced iTreg and Th17 cell differentiation","volume":"218","author":"Xu","year":"2021","journal-title":"J Exp Med"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0805","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/s13287-023-03263-1","article-title":"Perinatal tissue-derived exosomes ameliorate colitis in mice by regulating the Foxp3+Treg cells and gut microbiota","volume":"14","author":"Yan","year":"2023","journal-title":"Stem Cell Res Ther"},{"issue":"12","key":"10.1016\/j.autrev.2025.103977_bb0810","doi-asserted-by":"crossref","DOI":"10.1172\/JCI140755","article-title":"BMI1 maintains the Treg epigenomic landscape to prevent inflammatory bowel disease","volume":"131","author":"Gonzalez","year":"2021","journal-title":"J Clin Invest"},{"key":"10.1016\/j.autrev.2025.103977_bb0815","doi-asserted-by":"crossref","DOI":"10.1007\/s10753-024-02130-2","article-title":"atRA Attenuates high salt-driven EAE mainly through suppressing Th17-like regulatory T cell response mediated by the inhibition of IL-23R signaling pathway","author":"Tian","year":"2024","journal-title":"Inflammation"},{"issue":"8","key":"10.1016\/j.autrev.2025.103977_bb0820","doi-asserted-by":"crossref","first-page":"2168","DOI":"10.1111\/all.15722","article-title":"Anti-CD3 inhibits circulatory and tissue-resident memory CD4 T cells that drive asthma exacerbations in mice","volume":"78","author":"Sethi","year":"2023","journal-title":"Allergy"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0825","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1186\/s12931-023-02484-5","article-title":"Therapeutic properties of Helicobacter pylori-derived vacuolating cytotoxin a in an animal model of chronic allergic airway disease","volume":"24","author":"Raspe","year":"2023","journal-title":"Respir Res"},{"issue":"11","key":"10.1016\/j.autrev.2025.103977_bb0830","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1038\/s41590-019-0494-y","article-title":"CD103hi Treg cells constrain lung fibrosis induced by CD103lo tissue-resident pathogenic CD4 T cells","volume":"20","author":"Ichikawa","year":"2019","journal-title":"Nat Immunol"},{"issue":"11","key":"10.1016\/j.autrev.2025.103977_bb0835","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1164\/rccm.202305-0924OC","article-title":"Activation of CD8+ T cells in chronic obstructive pulmonary disease lung","volume":"208","author":"Villase\u00f1or-Altamirano","year":"2023","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"10.1016\/j.autrev.2025.103977_bb0840","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2005590118","article-title":"Single-cell transcriptomic analysis reveals the immune landscape of lung in steroid-resistant asthma exacerbation","volume":"118","author":"Wang","year":"2021","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"11","key":"10.1016\/j.autrev.2025.103977_bb0845","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20230112","article-title":"Allergen exposure functionally alters influenza-specific CD4+ Th1 memory cells in the lung","volume":"220","author":"R\u00fcterbusch","year":"2023","journal-title":"J Exp Med"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0850","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.jaci.2023.01.016","article-title":"Lung-resident CD69+ST2+ TH2 cells mediate long-term type 2 memory to inhaled antigen in mice","volume":"152","author":"Kobayashi","year":"2023","journal-title":"J Allergy Clin Immunol"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0855","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1186\/s12967-022-03481-w","article-title":"The treatment of Qibai Pingfei capsule on chronic obstructive pulmonary disease may be mediated by Th17\/Treg balance and gut-lung axis microbiota","volume":"20","author":"Jia","year":"2022","journal-title":"J Transl Med"},{"issue":"9","key":"10.1016\/j.autrev.2025.103977_bb0860","doi-asserted-by":"crossref","DOI":"10.1172\/JCI165689","article-title":"TXA2 attenuates allergic lung inflammation through regulation of Th2, Th9, and Treg differentiation","volume":"134","author":"Li","year":"2024","journal-title":"J Clin Invest"},{"issue":"6","key":"10.1016\/j.autrev.2025.103977_bb0865","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1016\/j.immuni.2021.04.002","article-title":"Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections","volume":"54","author":"Harb","year":"2021","journal-title":"Immunity"},{"issue":"5","key":"10.1016\/j.autrev.2025.103977_bb0870","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1016\/j.immuni.2017.04.028","article-title":"MenTORing immunity: mTOR signaling in the development and function of tissue-resident immune cells","volume":"46","author":"Jones","year":"2017","journal-title":"Immunity"},{"issue":"7","key":"10.1016\/j.autrev.2025.103977_bb0875","article-title":"CD103+CD8+ TRM cells accumulate in tumors of anti-PD-1-responder lung Cancer patients and are tumor-reactive lymphocytes enriched with Tc17","volume":"1","author":"Corgnac","year":"2020","journal-title":"Cell Rep Med"},{"issue":"9","key":"10.1016\/j.autrev.2025.103977_bb0880","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1038\/s41423-023-01064-3","article-title":"Regulation of CD8+ T memory and exhaustion by the mTOR signals","volume":"20","author":"Chen","year":"2023","journal-title":"Cell Mol Immunol"},{"issue":"12","key":"10.1016\/j.autrev.2025.103977_bb0885","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1038\/ni.3589","article-title":"Programs for the persistence, vigilance and control of human CD8+ lung-resident memory T cells","volume":"17","author":"Hombrink","year":"2016","journal-title":"Nat Immunol"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0890","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.111032","article-title":"mTORC1 signaling in antigen-presenting cells of the skin restrains CD8+ T cell priming","volume":"40","author":"Pelgrom","year":"2022","journal-title":"Cell Rep"},{"issue":"5","key":"10.1016\/j.autrev.2025.103977_bb0895","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1016\/j.celrep.2015.12.095","article-title":"Mammalian target of rapamycin complex 2 controls CD8 T cell memory differentiation in a Foxo1-dependent manner","volume":"14","author":"Zhang","year":"2016","journal-title":"Cell Rep"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0900","doi-asserted-by":"crossref","first-page":"2095","DOI":"10.1038\/s41467-018-04392-5","article-title":"mTOR coordinates transcriptional programs and mitochondrial metabolism of activated Treg subsets to protect tissue homeostasis","volume":"9","author":"Chapman","year":"2018","journal-title":"Nat Commun"},{"issue":"16","key":"10.1016\/j.autrev.2025.103977_bb0905","doi-asserted-by":"crossref","first-page":"2066","DOI":"10.3390\/cells12162066","article-title":"Metabolic disruption induced by mTOR signaling pathway inhibition in regulatory T-cell expansion for clinical application","volume":"12","author":"Gedaly","year":"2023","journal-title":"Cells"},{"key":"10.1016\/j.autrev.2025.103977_bb0910","article-title":"mTOR-dependent translation drives tumor infiltrating CD8+ effector and CD4+ Treg cells expansion. Topisirovic I, Rothlin CV, Topisirovic I, Larsson O, eds","volume":"10","author":"De Ponte","year":"2021","journal-title":"eLife"},{"issue":"8","key":"10.1016\/j.autrev.2025.103977_bb0915","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1016\/j.immuni.2021.06.007","article-title":"Transforming growth factor-\u03b2-regulated mTOR activity preserves cellular metabolism to maintain long-term T cell responses in chronic infection","volume":"54","author":"Gabriel","year":"2021","journal-title":"Immunity"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0920","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1186\/s12967-023-04789-x","article-title":"Activation of mucosal insulin receptor exacerbates intestinal inflammation by promoting tissue resident memory T cells differentiation through EZH2","volume":"22","author":"Li","year":"2024","journal-title":"J Transl Med"},{"issue":"4","key":"10.1016\/j.autrev.2025.103977_bb0925","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1093\/abbs\/gmab008","article-title":"mTOR pathway regulates the differentiation of peripheral blood Th2\/Treg cell subsets in patients with pemphigus vulgaris","volume":"53","author":"Lai","year":"2021","journal-title":"Acta Biochim Biophys Sin"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0930","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/s00018-024-05470-2","article-title":"SHIP-1 regulates the differentiation and function of Tregs via inhibiting mTORC1 activity","volume":"82","author":"Du","year":"2024","journal-title":"Cell Mol Life Sci"},{"issue":"3","key":"10.1016\/j.autrev.2025.103977_bb0935","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1111\/imm.13594","article-title":"mTORC2 contributes to systemic autoimmunity","volume":"168","author":"Zhou","year":"2023","journal-title":"Immunology"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0940","doi-asserted-by":"crossref","first-page":"37","DOI":"10.3390\/ijms23010037","article-title":"The energy sensor AMPK\u03b11 is critical in rapamycin-inhibition of mTORC1-S6K-induced T-cell memory","volume":"23","author":"Ara","year":"2022","journal-title":"Int J Mol Sci"},{"issue":"6","key":"10.1016\/j.autrev.2025.103977_bb0945","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/j.immuni.2009.04.014","article-title":"The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment","volume":"30","author":"Delgoffe","year":"2009","journal-title":"Immunity"},{"key":"10.1016\/j.autrev.2025.103977_bb0950","doi-asserted-by":"crossref","DOI":"10.1016\/j.clim.2022.109153","article-title":"mTOR signaling: a pivotal player in Treg cell dysfunction in systemic lupus erythematosus","volume":"245","author":"Zhao","year":"2022","journal-title":"Clin Immunol"},{"issue":"3","key":"10.1016\/j.autrev.2025.103977_bb0955","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1002\/art.40380","article-title":"Blockade of Treg cell differentiation and function by the Interleukin-21\u2013mechanistic target of rapamycin Axis via suppression of autophagy in patients with systemic lupus erythematosus","volume":"70","author":"Kato","year":"2018","journal-title":"Arthritis Rheumatol"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0960","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/imr.12845","article-title":"mTOR signaling at the crossroads of environmental signals and T-cell fate decisions","volume":"295","author":"Huang","year":"2020","journal-title":"Immunol Rev"},{"key":"10.1016\/j.autrev.2025.103977_bb0965","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2020.102424","article-title":"JAK\/STAT signaling controls the fate of CD8+CD103+ tissue-resident memory T cell in lupus nephritis","volume":"109","author":"Zhou","year":"2020","journal-title":"J Autoimmun"},{"issue":"7","key":"10.1016\/j.autrev.2025.103977_bb0970","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1012339","article-title":"IL-10 suppresses T cell expansion while promoting tissue-resident memory cell formation during SARS-CoV-2 infection in rhesus macaques","volume":"20","author":"Nelson","year":"2024","journal-title":"PLoS Pathog"},{"issue":"4","key":"10.1016\/j.autrev.2025.103977_bb0975","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1016\/j.mucimm.2024.04.004","article-title":"MAdCAM-1 co-stimulation combined with retinoic acid and TGF-\u03b2 induces blood CD8+ T cells to adopt a gut CD101+ TRM phenotype","volume":"17","author":"Girard","year":"2024","journal-title":"Mucosal Immunol"},{"issue":"24","key":"10.1016\/j.autrev.2025.103977_bb0980","doi-asserted-by":"crossref","first-page":"7072","DOI":"10.1158\/0008-5472.CAN-17-1487","article-title":"Paxillin binding to the cytoplasmic domain of CD103 promotes cell adhesion and effector functions for CD8+ resident memory T cells in tumors","volume":"77","author":"Gauthier","year":"2017","journal-title":"Cancer Res"},{"issue":"9","key":"10.1016\/j.autrev.2025.103977_bb0985","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.108085","article-title":"CD49a regulates cutaneous resident memory CD8+ T cell persistence and response","volume":"32","author":"Bromley","year":"2020","journal-title":"Cell Rep"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb0990","doi-asserted-by":"crossref","first-page":"6172","DOI":"10.1038\/s41598-017-06352-3","article-title":"Human intrahepatic CD69+CD8+ T cells have a tissue resident memory T cell phenotype with reduced cytolytic capacity","volume":"7","author":"Stelma","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.autrev.2025.103977_bb0995","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1146\/annurev-immunol-100219-020937","article-title":"Regulatory T cell development","volume":"38","author":"Savage","year":"2020","journal-title":"Annu Rev Immunol"},{"issue":"3","key":"10.1016\/j.autrev.2025.103977_bb1000","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1093\/rheumatology\/kead273","article-title":"Increased CD8+ tissue resident memory T cells, regulatory T cells and activated natural killer cells in systemic sclerosis lungs","volume":"63","author":"Padilla","year":"2024","journal-title":"Rheumatology"},{"issue":"77","key":"10.1016\/j.autrev.2025.103977_bb1005","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.abq3254","article-title":"Local IL-23 is required for proliferation and retention of skin-resident memory TH17 cells","volume":"7","author":"Whitley","year":"2022","journal-title":"Sci Immunol"},{"issue":"4","key":"10.1016\/j.autrev.2025.103977_bb1010","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/j.immuni.2025.03.004","article-title":"Soluble CTLA-4 regulates immune homeostasis and promotes resolution of inflammation by suppressing type 1 but allowing type 2 immunity","volume":"58","author":"Osaki","year":"2025","journal-title":"Immunity"},{"issue":"4","key":"10.1016\/j.autrev.2025.103977_bb1015","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.molmed.2023.01.003","article-title":"Upper respiratory tract mucosal immunity for SARS-CoV-2 vaccines","volume":"29","author":"Fraser","year":"2023","journal-title":"Trends Mol Med"},{"issue":"50","key":"10.1016\/j.autrev.2025.103977_bb1020","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.abb4432","article-title":"Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses","volume":"5","author":"Boland","year":"2020","journal-title":"Sci Immunol."},{"key":"10.1016\/j.autrev.2025.103977_bb1025","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.642711","article-title":"Staphylococcus aureus-specific tissue-resident memory CD4+ T cells are abundant in healthy human skin","volume":"12","author":"Hendriks","year":"2021","journal-title":"Front Immunol"},{"issue":"6","key":"10.1016\/j.autrev.2025.103977_bb1030","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.it.2013.03.003","article-title":"Effector and memory T cell responses to commensal bacteria","volume":"34","author":"Belkaid","year":"2013","journal-title":"Trends Immunol"},{"issue":"4","key":"10.1016\/j.autrev.2025.103977_bb1035","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1093\/ibd\/izae293","article-title":"Inflammation-induced Th17 cells synergize with the inflammation-trained microbiota to mediate host resiliency against intestinal injury","volume":"31","author":"Golob","year":"2025","journal-title":"Inflamm Bowel Dis"},{"issue":"12","key":"10.1016\/j.autrev.2025.103977_bb1040","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1016\/j.it.2024.11.005","article-title":"Please don\u2019t go: retinoic acid \u201cretains\u201d tissue-specific memory","volume":"45","author":"Stanczak","year":"2024","journal-title":"Trends Immunol"},{"issue":"1","key":"10.1016\/j.autrev.2025.103977_bb1045","doi-asserted-by":"crossref","first-page":"4077","DOI":"10.1038\/s41467-021-24331-1","article-title":"Microbial short-chain fatty acids modulate CD8+ T cell responses and improve adoptive immunotherapy for cancer","volume":"12","author":"Luu","year":"2021","journal-title":"Nat Commun"},{"issue":"15","key":"10.1016\/j.autrev.2025.103977_bb1050","doi-asserted-by":"crossref","first-page":"8272","DOI":"10.3390\/ijms23158272","article-title":"Regulation of CD4+ and CD8+ T cell biology by short-chain fatty acids and its relevance for autoimmune pathology","volume":"23","author":"Schiweck","year":"2022","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.autrev.2025.103977_bb1055","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.jconrel.2020.07.015","article-title":"Bilirubin nanomedicine alleviates psoriatic skin inflammation by reducing oxidative stress and suppressing pathogenic signaling","volume":"325","author":"Keum","year":"2020","journal-title":"J Control Release Off J Control Release Soc"},{"issue":"2","key":"10.1016\/j.autrev.2025.103977_bb1060","doi-asserted-by":"crossref","first-page":"528","DOI":"10.7150\/thno.87739","article-title":"Targeted modulation of intestinal epithelial regeneration and immune response in ulcerative colitis using dual-targeting bilirubin nanoparticles","volume":"14","author":"Zhuo","year":"2024","journal-title":"Theranostics"},{"key":"10.1016\/j.autrev.2025.103977_bb1065","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.jconrel.2020.08.054","article-title":"Therapeutic application and construction of bilirubin incorporated nanoparticles","volume":"328","author":"Yao","year":"2020","journal-title":"J Control Release Off J Control Release Soc."},{"issue":"11","key":"10.1016\/j.autrev.2025.103977_bb1070","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1007\/s12272-016-0823-8","article-title":"Targeting IL-17 in autoimmunity and inflammation","volume":"39","author":"Kim","year":"2016","journal-title":"Arch Pharm Res"},{"issue":"6","key":"10.1016\/j.autrev.2025.103977_bb1075","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2002787118","article-title":"Th2 cells lacking T-bet suppress naive and memory T cell responses via IL-10","volume":"118","author":"Mu\u00f1oz","year":"2021","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"378","key":"10.1016\/j.autrev.2025.103977_bb1080","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aaf8848","article-title":"A divergent population of autoantigen-responsive CD4+ T cells in infants prior to \u03b2 cell autoimmunity","volume":"9","author":"Heninger","year":"2017","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.autrev.2025.103977_bb1085","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.3389\/fimmu.2019.01177","article-title":"Differential pathogenic Th17 profile in mesenteric lymph nodes of Crohn\u2019s disease and ulcerative colitis patients","volume":"10","author":"Bsat","year":"2019","journal-title":"Front Immunol"},{"issue":"17","key":"10.1016\/j.autrev.2025.103977_bb1090","doi-asserted-by":"crossref","DOI":"10.1172\/JCI178253","article-title":"Systemic and skin-limited delayed-type drug hypersensitivity reactions associate with distinct resident and recruited T cell subsets","volume":"134","author":"Shah","year":"2024","journal-title":"J Clin Invest"},{"issue":"77","key":"10.1016\/j.autrev.2025.103977_bb1095","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.abl9925","article-title":"CD103 fate mapping reveals that intestinal CD103- tissue-resident memory T cells are the primary responders to secondary infection","volume":"7","author":"Fung","year":"2022","journal-title":"Sci Immunol."}],"container-title":["Autoimmunity Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568997225002381?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568997225002381?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T08:36:01Z","timestamp":1770280561000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1568997225002381"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":219,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["S1568997225002381"],"URL":"https:\/\/doi.org\/10.1016\/j.autrev.2025.103977","relation":{},"ISSN":["1568-9972"],"issn-type":[{"value":"1568-9972","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Trm-Treg Axis as a tissue-encoded immune checkpoint in chronic inflammation and autoimmunity","name":"articletitle","label":"Article Title"},{"value":"Autoimmunity Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.autrev.2025.103977","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"103977"}}