{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T16:37:04Z","timestamp":1792859824274,"version":"4.5.0"},"reference-count":208,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Autoimmunity Reviews"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.autrev.2026.104151","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T15:19:45Z","timestamp":1785424785000},"page":"104151","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Aberrant neutrophil and complement activation in thrombotic microangiopathies in pregnancy - Is there a missing link?"],"prefix":"10.1016","volume":"25","author":[{"given":"Maria","family":"Zaimi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Kambas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smaragdi","family":"Marinaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianna","family":"Theodora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgios","family":"Daskalakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleni","family":"Frangou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.autrev.2026.104151_bb0005","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1002\/JLB.2MR0220-549R","article-title":"ICAM-1: a master regulator of cellular responses in inflammation, injury resolution, and tumorigenesis","volume":"108","author":"Bui","year":"2020","journal-title":"J Leukoc Biol"},{"issue":"4","key":"10.1016\/j.autrev.2026.104151_bb0010","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1080\/10641950801958067","article-title":"Neutrophils, but not lymphocytes or monocytes, infiltrate maternal systemic vasculature in women with preeclampsia","volume":"27","author":"Cadden","year":"2008","journal-title":"Hypertens Preg"},{"issue":"5","key":"10.1016\/j.autrev.2026.104151_bb0015","article-title":"Targeting neutrophil extracellular trap formation: exploring promising pharmacological strategies for the treatment of preeclampsia","volume":"17","author":"Gonz\u00e1lez","year":"2024","journal-title":"Pharmaceuticals (Basel, Switzerland)"},{"issue":"4","key":"10.1016\/j.autrev.2026.104151_bb0020","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.semnephrol.2017.05.010","article-title":"Acute kidney injury in pregnancy","volume":"37","author":"Jim","year":"2017","journal-title":"Semin Nephrol"},{"key":"10.1016\/j.autrev.2026.104151_bb0025","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.3389\/fimmu.2017.01866","article-title":"\u03922 Integrins as regulators of dendritic cell, monocyte, and macrophage function","volume":"8","author":"Schittenhelm","year":"2017","journal-title":"Front Immunol"},{"key":"10.1016\/j.autrev.2026.104151_bb0030","article-title":"Hypertensive disorders of pregnancy and the recent increase in obstetric acute renal failure in Canada: population based retrospective cohort study","volume":"349","author":"Mehrabadi","year":"2014","journal-title":"BMJ (Clin Res Ed)"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0035","doi-asserted-by":"crossref","first-page":"50","DOI":"10.2215\/CJN.06440616","article-title":"Pathogenic variants in complement genes and risk of atypical hemolytic uremic syndrome relapse after eculizumab discontinuation","volume":"12","author":"Fakhouri","year":"2017","journal-title":"Clin J Am Soc Nephrol"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0040","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1053\/j.ajkd.2018.06.006","article-title":"Renal disorders in pregnancy: core curriculum 2019","volume":"73","author":"Suarez","year":"2019","journal-title":"Am J Kidney Dis"},{"issue":"3","key":"10.1016\/j.autrev.2026.104151_bb0045","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1159\/000505894","article-title":"Pregnancy-related acute kidney injury in the United States: clinical outcomes and health care utilization","volume":"51","author":"Shah","year":"2020","journal-title":"Am J Nephrol"},{"issue":"6","key":"10.1016\/j.autrev.2026.104151_bb0050","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1093\/ndt\/gfaa259","article-title":"Staging pregnancy-related acute kidney injury according to kidney disease: improving global outcomes guidelines: what are the barriers?","volume":"36","author":"de Buhren","year":"2021","journal-title":"Nephrol Dial Transpl"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0055","first-page":"1","volume":"133","author":"ACOG Practice Bulletin No. 202: Gestational Hypertension and Preeclampsia","year":"2019","journal-title":"Obstetr Gynecol"},{"issue":"4","key":"10.1016\/j.autrev.2026.104151_bb0060","doi-asserted-by":"crossref","first-page":"R204","DOI":"10.1186\/cc2872","article-title":"Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the second international consensus conference of the Acute Dialysis Quality Initiative (ADQI) group","volume":"8","author":"Bellomo","year":"2004","journal-title":"Crit Care"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb0065","doi-asserted-by":"crossref","first-page":"R31","DOI":"10.1186\/cc5713","article-title":"Acute kidney injury network: report of an Initiative to improve outcomes in acute kidney injury","volume":"11","author":"Mehta","year":"2007","journal-title":"Crit Care"},{"issue":"4","key":"10.1016\/j.autrev.2026.104151_bb0070","doi-asserted-by":"crossref","first-page":"c179","DOI":"10.1159\/000339789","article-title":"KDIGO clinical practice guidelines for acute kidney injury","volume":"120","author":"Khwaja","year":"2012","journal-title":"Nephron Clin Pract"},{"issue":"19","key":"10.1016\/j.autrev.2026.104151_bb0075","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1182\/blood.2020005221","article-title":"Management of thrombotic microangiopathy in pregnancy and postpartum: report from an international working group","volume":"136","author":"Fakhouri","year":"2020","journal-title":"Blood"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb0080","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1111\/jth.13571","article-title":"Consensus on the standardization of terminology in thrombotic thrombocytopenic purpura and related thrombotic microangiopathies","volume":"15","author":"Scully","year":"2017","journal-title":"J Thromb Haemost"},{"issue":"6","key":"10.1016\/j.autrev.2026.104151_bb0085","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1053\/j.ackd.2020.06.002","article-title":"Acute kidney injury in pregnancy","volume":"27","author":"Taber-Hight","year":"2020","journal-title":"Adv Chronic Kidney Dis"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.rpth.2023.100084","article-title":"Etiology and outcomes: thrombotic microangiopathies in pregnancy","volume":"7","author":"Scully","year":"2023","journal-title":"Res Pract Thromb Haemost"},{"issue":"6","key":"10.1016\/j.autrev.2026.104151_bb0095","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1053\/j.ajkd.2009.12.036","article-title":"Kidney disease after preeclampsia: a systematic review and meta-analysis","volume":"55","author":"McDonald","year":"2010","journal-title":"Am J Kidney Dis"},{"issue":"3","key":"10.1016\/j.autrev.2026.104151_bb0100","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/j.kint.2019.03.033","article-title":"A systematic review and meta-analysis indicates long-term risk of chronic and end-stage kidney disease after preeclampsia","volume":"96","author":"Covella","year":"2019","journal-title":"Kidney Int"},{"issue":"5","key":"10.1016\/j.autrev.2026.104151_bb0105","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1681\/ASN.2009070706","article-title":"Pregnancy-associated hemolytic uremic syndrome revisited in the era of complement gene mutations","volume":"21","author":"Fakhouri","year":"2010","journal-title":"J Am Soc Nephrol"},{"issue":"10","key":"10.1016\/j.autrev.2026.104151_bb0110","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1111\/eci.12130","article-title":"Gene expression and regulation in systemic lupus erythematosus","volume":"43","author":"Frangou","year":"2013","journal-title":"Eur J Clin Investig"},{"issue":"8","key":"10.1016\/j.autrev.2026.104151_bb0115","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.autrev.2019.06.011","article-title":"An emerging role of neutrophils and NETosis in chronic inflammation and fibrosis in systemic lupus erythematosus (SLE) and ANCA-associated vasculitides (AAV): implications for the pathogenesis and treatment","volume":"18","author":"Frangou","year":"2019","journal-title":"Autoimmun Rev"},{"issue":"11","key":"10.1016\/j.autrev.2026.104151_bb0120","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1016\/j.autrev.2017.09.012","article-title":"Neutrophil extracellular traps (NETs) in autoimmune diseases: a comprehensive review","volume":"16","author":"Lee","year":"2017","journal-title":"Autoimmun Rev"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb0125","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1136\/annrheumdis-2018-213181","article-title":"REDD1\/autophagy pathway promotes thromboinflammation and fibrosis in human systemic lupus erythematosus (SLE) through NETs decorated with tissue factor (TF) and interleukin-17A (IL-17A)","volume":"78","author":"Frangou","year":"2019","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.autrev.2026.104151_bb0130","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.24437","article-title":"Diverse stimuli engage different neutrophil extracellular trap pathways","volume":"6","author":"Kenny","year":"2017","journal-title":"ELife"},{"issue":"5663","key":"10.1016\/j.autrev.2026.104151_bb0135","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1126\/science.1092385","article-title":"Neutrophil extracellular traps kill bacteria","volume":"303","author":"Brinkmann","year":"2004","journal-title":"Science (New York, N.Y.)"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb0140","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1038\/nri.2017.105","article-title":"Neutrophil extracellular traps in immunity and disease","volume":"18","author":"Papayannopoulos","year":"2018","journal-title":"Nat Rev Immunol"},{"issue":"10","key":"10.1016\/j.autrev.2026.104151_bb0145","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1136\/annrheumdis-2013-203430","article-title":"Tissue factor expression in neutrophil extracellular traps and neutrophil derived microparticles in antineutrophil cytoplasmic antibody associated vasculitis may promote thromboinflammation and the thrombophilic state associated with the disease","volume":"73","author":"Kambas","year":"2014","journal-title":"Ann Rheum Dis"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0150","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.ajog.2003.07.003","article-title":"Neutrophils are stimulated by syncytiotrophoblast microvillous membranes to generate superoxide radicals in women with preeclampsia","volume":"190","author":"Aly","year":"2004","journal-title":"Am J Obstet Gynecol"},{"issue":"11","key":"10.1016\/j.autrev.2026.104151_bb0155","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1016\/j.humimm.2005.11.003","article-title":"Induction of neutrophil extracellular DNA lattices by placental microparticles and IL-8 and their presence in preeclampsia","volume":"66","author":"Gupta","year":"2005","journal-title":"Hum Immunol"},{"issue":"6","key":"10.1016\/j.autrev.2026.104151_bb0160","doi-asserted-by":"crossref","first-page":"730","DOI":"10.3899\/jrheum.220752","article-title":"The role of complement in autoimmune disease-associated thrombotic microangiopathy and the potential for therapeutics","volume":"50","author":"Java","year":"2023","journal-title":"J Rheumatol"},{"issue":"21","key":"10.1016\/j.autrev.2026.104151_bb0165","doi-asserted-by":"crossref","first-page":"2847","DOI":"10.1182\/blood-2016-11-709865","article-title":"HUS and atypical HUS","volume":"129","author":"Jokiranta","year":"2017","journal-title":"Blood"},{"issue":"7","key":"10.1016\/j.autrev.2026.104151_bb0170","doi-asserted-by":"crossref","first-page":"4794","DOI":"10.4049\/jimmunol.177.7.4794","article-title":"A novel C5a receptor-tissue factor cross-talk in neutrophils links innate immunity to coagulation pathways","volume":"177","author":"Ritis","year":"2006","journal-title":"J Immunol (Baltimore, Md.: 1950)"},{"issue":"13","key":"10.1016\/j.autrev.2026.104151_bb0175","doi-asserted-by":"crossref","first-page":"2170","DOI":"10.1016\/j.molimm.2010.05.009","article-title":"Complement activation on platelets: implications for vascular inflammation and thrombosis","volume":"47","author":"Peerschke","year":"2010","journal-title":"Mol Immunol"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0180","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1038\/s41423-018-0024-0","article-title":"NETosis, complement, and coagulation: a triangular relationship","volume":"16","author":"de Bont","year":"2019","journal-title":"Cell Mol Immunol"},{"key":"10.1016\/j.autrev.2026.104151_bb0185","doi-asserted-by":"crossref","first-page":"157","DOI":"10.3389\/fimmu.2012.00157","article-title":"Neutrophil arrest by LFA-1 activation","volume":"3","author":"Lefort","year":"2012","journal-title":"Front Immunol"},{"issue":"12","key":"10.1016\/j.autrev.2026.104151_bb0190","doi-asserted-by":"crossref","first-page":"4638","DOI":"10.1172\/JCI81660","article-title":"Platelet-derived HMGB1 is a critical mediator of thrombosis","volume":"125","author":"Vogel","year":"2015","journal-title":"J Clin Invest"},{"issue":"7","key":"10.1016\/j.autrev.2026.104151_bb0195","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23073868","article-title":"Beyond hemostasis: platelet innate immune interactions and thromboinflammation","volume":"23","author":"Mandel","year":"2022","journal-title":"Int J Mol Sci"},{"issue":"8","key":"10.1016\/j.autrev.2026.104151_bb0200","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1038\/nm.2184","article-title":"Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases","volume":"16","author":"Massberg","year":"2010","journal-title":"Nat Med"},{"issue":"9","key":"10.1016\/j.autrev.2026.104151_bb0205","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0045427","article-title":"Autophagy mediates the delivery of thrombogenic tissue factor to neutrophil extracellular traps in human sepsis","volume":"7","author":"Kambas","year":"2012","journal-title":"PLoS One"},{"issue":"10","key":"10.1016\/j.autrev.2026.104151_bb0685","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines11102851","article-title":"Obesity correlates with chronic inflammation of the innate immune system in preeclampsia and HELLP syndrome during pregnancy","volume":"11","author":"Rimboeck","year":"2023","journal-title":"Biomedicines"},{"key":"10.1016\/j.autrev.2026.104151_bb0765","doi-asserted-by":"crossref","first-page":"240","DOI":"10.3389\/fimmu.2019.00240","article-title":"Elevated systemic pentraxin-3 is associated with complement consumption in the acute phase of thrombotic microangiopathies","volume":"10","author":"Trojnar","year":"2019","journal-title":"Front Immunol"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0360","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.ekir.2016.08.015","article-title":"Complement activation induces neutrophil adhesion and neutrophil-platelet aggregate formation on vascular endothelial cells","volume":"2","author":"Riedl","year":"2017","journal-title":"Kidney Int Rep"},{"issue":"7","key":"10.1016\/j.autrev.2026.104151_bb0325","doi-asserted-by":"crossref","first-page":"3522","DOI":"10.4049\/jimmunol.1102404","article-title":"Neutrophil extracellular traps that are not degraded in systemic lupus erythematosus activate complement exacerbating the disease","volume":"188","author":"Leffler","year":"2012","journal-title":"J. Immunol. (Baltimore, Md.: 1950)"},{"issue":"11","key":"10.1016\/j.autrev.2026.104151_bb0840","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.3324\/haematol.2016.149021","article-title":"Human neutrophil peptides and complement factor bb in pathogenesis of acquired thrombotic thrombocytopenic purpura","volume":"101","author":"Cao","year":"2016","journal-title":"Haematologica"},{"key":"10.1016\/j.autrev.2026.104151_bb0210","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.882298","article-title":"Distinct roles of classical and lectin pathways of complement in preeclamptic placentae","volume":"13","author":"Belmonte","year":"2022","journal-title":"Front Immunol"},{"issue":"4","key":"10.1016\/j.autrev.2026.104151_bb0215","article-title":"Lectin pathway proteins of the complement system in normotensive pregnancy and pre-eclampsia","volume":"81","author":"Larsen","year":"2019","journal-title":"Am J Reprod Immunol (New York, N.Y.:1989)"},{"issue":"3","key":"10.1016\/j.autrev.2026.104151_bb0220","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1001013","article-title":"Mutations in complement regulatory proteins predispose to preeclampsia: a genetic analysis of the PROMISSE cohort","volume":"8","author":"Salmon","year":"2011","journal-title":"PLoS Med"},{"issue":"2S","key":"10.1016\/j.autrev.2026.104151_bb0225","doi-asserted-by":"crossref","first-page":"S1059","DOI":"10.1016\/j.ajog.2020.09.038","article-title":"Complement activation and regulation in preeclampsia and hemolysis, elevated liver enzymes, and low platelet count syndrome","volume":"226","author":"Burwick","year":"2022","journal-title":"Am J Obstet Gynecol"},{"issue":"7\u20138","key":"10.1016\/j.autrev.2026.104151_bb0230","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1016\/j.molimm.2010.01.021","article-title":"Activation of the complement system in normal pregnancy and preeclampsia","volume":"47","author":"Derzsy","year":"2010","journal-title":"Mol Immunol"},{"issue":"4","key":"10.1016\/j.autrev.2026.104151_bb0235","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1080\/10641955.2016.1190845","article-title":"Correlations between complement system\u2019s activation factors and anti-angiogenesis factors in plasma of patients with early\/late-onset severe preeclampsia","volume":"35","author":"He","year":"2016","journal-title":"Hypertens Preg"},{"issue":"5","key":"10.1016\/j.autrev.2026.104151_bb0240","article-title":"Upregulation and release of soluble Fms-like tyrosine kinase receptor 1 mediated by complement activation in human syncytiotrophoblast cells","volume":"80","author":"Banadakoppa","year":"2018","journal-title":"Am J Reprod Immunol (New York, NY: 1989)"},{"issue":"4","key":"10.1016\/j.autrev.2026.104151_bb0245","first-page":"698","article-title":"Enhanced anaphylatoxin and terminal C5b-9 complement complex formation in patients with the syndrome of hemolysis, elevated liver enzymes, and low platelet count","volume":"76","author":"Haeger","year":"1990","journal-title":"Obstet Gynecol"},{"issue":"4","key":"10.1016\/j.autrev.2026.104151_bb0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajog.2007.10.793","article-title":"Alternative complement pathway activation fragment bb in early pregnancy as a predictor of preeclampsia","volume":"198","author":"Lynch","year":"2008","journal-title":"Am J Obstet Gynecol"},{"issue":"3","key":"10.1016\/j.autrev.2026.104151_bb0255","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1080\/10641955.2019.1640725","article-title":"Placental SFLT1 is associated with complement activation and syncytiotrophoblast damage in preeclampsia","volume":"38","author":"Collier","year":"2019","journal-title":"Hypertens Preg"},{"key":"10.1016\/j.autrev.2026.104151_bb0260","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.thromres.2020.08.038","article-title":"Genetic and molecular evidence for complement dysregulation in patients with HELLP syndrome","volume":"196","author":"Bazzan","year":"2020","journal-title":"Thromb Res"},{"issue":"6","key":"10.1016\/j.autrev.2026.104151_bb0265","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.99128","article-title":"Germline mutations in the alternative pathway of complement predispose to HELLP syndrome","volume":"3","author":"Vaught","year":"2018","journal-title":"JCI Insight"},{"issue":"12","key":"10.1016\/j.autrev.2026.104151_bb0270","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.2215\/CJN.05830519","article-title":"Complement activation and thrombotic microangiopathies","volume":"14","author":"Palomo","year":"2019","journal-title":"Clin J Am Soc Nephrol"},{"issue":"6","key":"10.1016\/j.autrev.2026.104151_bb0275","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/j.semnephrol.2013.08.003","article-title":"Atypical hemolytic uremic syndrome","volume":"33","author":"Kavanagh","year":"2013","journal-title":"Semin Nephrol"},{"key":"10.1016\/j.autrev.2026.104151_bb0280","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1146\/annurev-pathol-012615-044145","article-title":"Complement dysregulation and disease: insights from contemporary genetics","volume":"12","author":"Liszewski","year":"2017","journal-title":"Annu Rev Pathol"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb0285","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1182\/blood-2009-05-221549","article-title":"Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome","volume":"115","author":"Moore","year":"2010","journal-title":"Blood"},{"issue":"15","key":"10.1016\/j.autrev.2026.104151_bb0290","doi-asserted-by":"crossref","first-page":"2359","DOI":"10.1182\/blood-2014-10-609073","article-title":"Mapping interactions between complement C3 and regulators using mutations in atypical hemolytic uremic syndrome","volume":"125","author":"Schramm","year":"2015","journal-title":"Blood"},{"issue":"13","key":"10.1016\/j.autrev.2026.104151_bb0295","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1182\/blood.2019001040","article-title":"Synergistic effects of ADAMTS13 deficiency and complement activation in pathogenesis of thrombotic microangiopathy","volume":"134","author":"Zheng","year":"2019","journal-title":"Blood"},{"issue":"4","key":"10.1016\/j.autrev.2026.104151_bb0300","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/aji.12404","article-title":"Overactivation of complement alternative pathway in postpartum atypical hemolytic uremic syndrome patients with renal involvement","volume":"74","author":"Song","year":"2015","journal-title":"Am J Reprod Immunol (New York, N.Y.: 1989)"},{"issue":"19","key":"10.1016\/j.autrev.2026.104151_bb0305","doi-asserted-by":"crossref","first-page":"4012","DOI":"10.1182\/blood-2013-03-487694","article-title":"Complement factor H mutations are present in ADAMTS13-deficient, ticlopidine-associated thrombotic microangiopathies","volume":"121","author":"Chapin","year":"2013","journal-title":"Blood"},{"issue":"18","key":"10.1016\/j.autrev.2026.104151_bb0310","first-page":"2278","article-title":"Complement activation and renal dysfunction in patients with acquired thrombotic thrombocytopenic purpura","volume":"141","author":"Cugno","year":"2023","journal-title":"Blood"},{"issue":"5","key":"10.1016\/j.autrev.2026.104151_bb0315","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1111\/j.1538-7836.2012.04674.x","article-title":"Complement activation in thrombotic thrombocytopenic purpura","volume":"10","author":"R\u00e9ti","year":"2012","journal-title":"J Thromb Haemost"},{"issue":"6","key":"10.1016\/j.autrev.2026.104151_bb0320","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1111\/bjh.12707","article-title":"Complement and cytokine response in acute thrombotic thrombocytopenic purpura","volume":"164","author":"Westwood","year":"2014","journal-title":"Br J Haematol"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb0330","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1007\/s12016-020-08804-7","article-title":"A review of neutrophil extracellular traps (NETs) in disease: potential anti-NETs therapeutics","volume":"61","author":"Mutua","year":"2021","journal-title":"Clin Rev Allergy Immunol"},{"issue":"10","key":"10.1016\/j.autrev.2026.104151_bb0335","doi-asserted-by":"crossref","first-page":"2536","DOI":"10.1182\/bloodadvances.2023011617","article-title":"Targeting neutrophil extracellular trap accumulation under flow in patients with immune-mediated thrombotic thrombocytopenic purpura","volume":"8","author":"Yada","year":"2024","journal-title":"Blood Adv"},{"issue":"3","key":"10.1016\/j.autrev.2026.104151_bb0340","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.1002\/jcp.27189","article-title":"Toll-like receptors signaling network in pre-eclampsia: an updated review","volume":"234","author":"Afkham","year":"2019","journal-title":"J Cell Physiol"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb0345","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.ejogrb.2012.09.026","article-title":"Pathogenesis of the syndrome of hemolysis, elevated liver enzymes, and low platelet count (HELLP): a review","volume":"166","author":"Abildgaard","year":"2013","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0350","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1038\/s41598-017-18553-x","article-title":"Role and mechanism of AT1-AA in the pathogenesis of HELLP syndrome","volume":"8","author":"Bu","year":"2018","journal-title":"Sci Rep"},{"issue":"8","key":"10.1016\/j.autrev.2026.104151_bb0355","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1038\/s41423-023-01002-3","article-title":"IL-32-driven neutrophil activation in preeclampsia","volume":"20","author":"Liu","year":"2023","journal-title":"Cell Mol Immunol"},{"issue":"21","key":"10.1016\/j.autrev.2026.104151_bb0365","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232113218","article-title":"Aspirin inhibits the inflammatory response of protease-activated receptor 1 in pregnancy neutrophils: implications for treating women with preeclampsia","volume":"23","author":"Walsh","year":"2022","journal-title":"Int J Mol Sci"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb0370","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1111\/jth.15176","article-title":"Plasma levels of S100A8\/A9, histone\/DNA complexes, and cell-free DNA predict adverse outcomes of immune thrombotic thrombocytopenic purpura","volume":"19","author":"Sui","year":"2021","journal-title":"J Thromb Haemost"},{"issue":"10","key":"10.1016\/j.autrev.2026.104151_bb0375","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1136\/ard-2023-224609","article-title":"2023 ACR\/EULAR antiphospholipid syndrome classification criteria","volume":"82","author":"Barbhaiya","year":"2023","journal-title":"Ann Rheum Dis"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0380","doi-asserted-by":"crossref","DOI":"10.1136\/lupus-2015-000131","article-title":"Lupus anticoagulant is the main predictor of adverse pregnancy outcomes in APL-positive patients: validation of PROMISSE study results","volume":"3","author":"Yelnik","year":"2016","journal-title":"Lupus Sci Med"},{"key":"10.1016\/j.autrev.2026.104151_bb0385","doi-asserted-by":"crossref","DOI":"10.1016\/j.jri.2024.104316","article-title":"Non-criteria and criteria antiphospholipid antibodies and their association with pregnancy outcomes in women with a history of miscarriage: a retrospective study","volume":"165","author":"Junmiao Xiang","year":"2024","journal-title":"J Reprod Immunol"},{"issue":"10","key":"10.1016\/j.autrev.2026.104151_bb0390","article-title":"IgG and IgM anti-phosphatidylserine\/prothrombin complex antibody detection may improve classification accuracy of systemic lupus erythematosus and antiphospholipid antibody syndrome","volume":"7","author":"Donath","year":"2025","journal-title":"ACR Open Rheumatol"},{"issue":"12","key":"10.1016\/j.autrev.2026.104151_bb0395","doi-asserted-by":"crossref","first-page":"6690","DOI":"10.1111\/jcmm.15321","article-title":"Antiphospholipid antibody-activated NETs exacerbate trophoblast and endothelial cell injury in obstetric antiphospholipid syndrome","volume":"24","author":"Lu","year":"2020","journal-title":"J Cell Mol Med"},{"issue":"11","key":"10.1016\/j.autrev.2026.104151_bb0400","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1172\/JCI200318817","article-title":"Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome","volume":"112","author":"Girardi","year":"2003","journal-title":"J Clin Invest"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0405","doi-asserted-by":"crossref","first-page":"6870","DOI":"10.1038\/s41598-021-86390-0","article-title":"The enrichment of neutrophil extracellular traps impair the placentas of systemic lupus erythematosus through accumulating decidual NK cells","volume":"11","author":"Jiang","year":"2021","journal-title":"Sci Rep"},{"key":"10.1016\/j.autrev.2026.104151_bb0410","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.preghy.2021.09.008","article-title":"The 2021 international society for the study of hypertension in pregnancy classification, diagnosis & Management Recommendations for international practice","volume":"27","author":"Magee","year":"2022","journal-title":"Pregn Hypertens"},{"issue":"10022","key":"10.1016\/j.autrev.2026.104151_bb0415","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/S0140-6736(15)00070-7","article-title":"Pre-eclampsia","volume":"387","author":"Mol","year":"2016","journal-title":"Lancet (London, England)"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0420","doi-asserted-by":"crossref","first-page":"R27","DOI":"10.1530\/JOE-16-0340","article-title":"Vascular adaptation in pregnancy and endothelial dysfunction in preeclampsia","volume":"232","author":"Boeldt","year":"2017","journal-title":"J Endocrinol"},{"issue":"4","key":"10.1016\/j.autrev.2026.104151_bb0425","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1111\/imm.13392","article-title":"Neutrophils in pregnancy: new insights into innate and adaptive immune regulation","volume":"164","author":"Bert","year":"2021","journal-title":"Immunology"},{"issue":"9741","key":"10.1016\/j.autrev.2026.104151_bb0430","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/S0140-6736(10)60279-6","article-title":"Pre-eclampsia","volume":"376","author":"Steegers","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.autrev.2026.104151_bb0435","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.biopha.2018.10.082","article-title":"Preeclampsia: a close look at renal dysfunction","volume":"109","author":"Sani","year":"2019","journal-title":"Biomed Pharmacother"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0475","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/S0002-9378(98)70254-6","article-title":"Normal pregnancy and preeclampsia both produce inflammatory changes in peripheral blood leukocytes akin to those of sepsis","volume":"179","author":"Sacks","year":"1998","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.autrev.2026.104151_bb0480","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1196\/annals.1368.015","article-title":"Occurrence of neutrophil extracellular DNA traps (NETs) in pre-eclampsia: a link with elevated levels of cell-free DNA?","volume":"1075","author":"Gupta","year":"2006","journal-title":"Ann N Y Acad Sci"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb0485","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s00281-007-0073-4","article-title":"Neutrophil NETs: a novel contributor to preeclampsia-associated placental hypoxia?","volume":"29","author":"Gupta","year":"2007","journal-title":"Semin Immunopathol"},{"issue":"12","key":"10.1016\/j.autrev.2026.104151_bb0490","doi-asserted-by":"crossref","first-page":"2064","DOI":"10.1055\/s-0038-1675788","article-title":"Increased neutrophil activation and plasma DNA levels in patients with pre-eclampsia","volume":"118","author":"Hu","year":"2018","journal-title":"Thromb Haemost"},{"issue":"7","key":"10.1016\/j.autrev.2026.104151_bb0495","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1136\/annrheumdis-2013-204837","article-title":"Neutrophil extracellular traps induce endothelial dysfunction in systemic lupus erythematosus through the activation of matrix metalloproteinase-2","volume":"74","author":"Carmona-Rivera","year":"2015","journal-title":"Ann Rheum Dis"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb0500","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1002\/jcla.20295","article-title":"Evaluation of metalloproteinases 2 and 9 and their inhibitors in physiologic and pre-eclamptic pregnancy","volume":"23","author":"Montagnana","year":"2009","journal-title":"J Clin Lab Anal"},{"issue":"36","key":"10.1016\/j.autrev.2026.104151_bb0505","doi-asserted-by":"crossref","first-page":"15880","DOI":"10.1073\/pnas.1005743107","article-title":"Extracellular DNA traps promote thrombosis","volume":"107","author":"Fuchs","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"issue":"10","key":"10.1016\/j.autrev.2026.104151_bb0510","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1182\/blood-2016-09-741298","article-title":"Platelets and neutrophil extracellular traps collaborate to promote intravascular coagulation during sepsis in mice","volume":"129","author":"McDonald","year":"2017","journal-title":"Blood"},{"issue":"49","key":"10.1016\/j.autrev.2026.104151_bb0515","doi-asserted-by":"crossref","first-page":"41949","DOI":"10.1074\/jbc.M111.301218","article-title":"Effects of extracellular DNA on plasminogen activation and fibrinolysis","volume":"286","author":"Komissarov","year":"2011","journal-title":"J Biol Chem"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0520","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1111\/j.1538-7836.2011.04544.x","article-title":"Neutrophil extracellular traps promote deep vein thrombosis in mice","volume":"10","author":"Brill","year":"2012","journal-title":"J Thromb Haemost"},{"issue":"6","key":"10.1016\/j.autrev.2026.104151_bb0525","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1182\/blood-2012-02-412197","article-title":"Circulating DNA and myeloperoxidase indicate disease activity in patients with thrombotic microangiopathies","volume":"120","author":"Fuchs","year":"2012","journal-title":"Blood"},{"issue":"6367","key":"10.1016\/j.autrev.2026.104151_bb0530","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1126\/science.aam8897","article-title":"Host DNases prevent vascular occlusion by neutrophil extracellular traps","volume":"358","author":"Jim\u00e9nez-Alc\u00e1zar","year":"2017","journal-title":"Science (New York, N.Y.)"},{"issue":"4","key":"10.1016\/j.autrev.2026.104151_bb0440","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1038\/s41581-022-00670-0","article-title":"The role of immune cells and mediators in preeclampsia","volume":"19","author":"Deer","year":"2023","journal-title":"Nat Rev Nephrol"},{"issue":"12","key":"10.1016\/j.autrev.2026.104151_bb0445","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0166940","article-title":"MiR-125b enhances IL-8 production in early-onset severe preeclampsia by targeting sphingosine-1-phosphate lyase 1","volume":"11","author":"Yang","year":"2016","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0450","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1007\/s43032-021-00605-3","article-title":"Epigenetic regulation of interleukin-17-related genes and their potential roles in neutrophil vascular infiltration in preeclampsia","volume":"29","author":"Walsh","year":"2022","journal-title":"Reprod Sci (Thousand Oaks, Calif.)"},{"issue":"12","key":"10.1016\/j.autrev.2026.104151_bb0455","doi-asserted-by":"crossref","first-page":"6287","DOI":"10.4049\/jimmunol.1200385","article-title":"IL-17 and TNF-\u03b1 sustain neutrophil recruitment during inflammation through synergistic effects on endothelial activation","volume":"188","author":"Griffin","year":"2012","journal-title":"J Immunol (Baltimore, Md.: 1950)"},{"key":"10.1016\/j.autrev.2026.104151_bb0460","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.pharmthera.2017.02.025","article-title":"Interleukin 32, inflammation and cancer","volume":"174","author":"Hong","year":"2017","journal-title":"Pharmacol Ther"},{"key":"10.1016\/j.autrev.2026.104151_bb0465","doi-asserted-by":"crossref","first-page":"1259989","DOI":"10.3389\/fimmu.2023.1259989","article-title":"Surface toll-like receptor 9 on immune cells and its immunomodulatory effect","volume":"14","author":"Kou","year":"2023","journal-title":"Front Immunol"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0470","doi-asserted-by":"crossref","first-page":"5920","DOI":"10.1038\/s41598-019-42551-w","article-title":"Activation of a TLR9 mediated innate immune response in preeclampsia","volume":"9","author":"Williamson","year":"2019","journal-title":"Sci Rep"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0535","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1161\/01.HYP.0000130483.83154.37","article-title":"Neutrophils infiltrate resistance-sized vessels of subcutaneous fat in women with preeclampsia","volume":"44","author":"Leik","year":"2004","journal-title":"Hypertension (Dallas, Tex.: 1979)"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0540","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1161\/hy0102.100778","article-title":"Activation of leukocytes during the uteroplacental passage in preeclampsia","volume":"39","author":"Mellembakken","year":"2002","journal-title":"Hypertension (Dallas, Tex.: 1979)"},{"issue":"4","key":"10.1016\/j.autrev.2026.104151_bb0545","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1038\/s41423-021-00636-5","article-title":"Placenta-derived IL-32\u03b2 activates neutrophils to promote preeclampsia development","volume":"18","author":"Liu","year":"2021","journal-title":"Cell Mol Immunol"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0550","first-page":"131","article-title":"Interleukin-32: a cytokine and inducer of TNFalpha","volume":"22","author":"Kim","year":"2005","journal-title":"Immunity"},{"issue":"10","key":"10.1016\/j.autrev.2026.104151_bb0555","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1055\/s-0029-1223285","article-title":"Increased neutrophil numbers account for leukocytosis in women with preeclampsia","volume":"26","author":"Canzoneri","year":"2009","journal-title":"Am J Perinatol"},{"issue":"4","key":"10.1016\/j.autrev.2026.104151_bb0560","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1080\/14767050500072722","article-title":"Normal pregnancy is characterized by systemic activation of the complement system","volume":"17","author":"Richani","year":"2005","journal-title":"J Maternal-Fetal Neonatal Med"},{"key":"10.1016\/j.autrev.2026.104151_bb0565","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.3389\/fimmu.2020.01681","article-title":"Essential role of complement in pregnancy: from implantation to parturition and beyond","volume":"11","author":"Girardi","year":"2020","journal-title":"Front Immunol"},{"issue":"7","key":"10.1016\/j.autrev.2026.104151_bb0570","doi-asserted-by":"crossref","first-page":"4420","DOI":"10.4049\/jimmunol.0903215","article-title":"An alternative role of C1q in cell migration and tissue remodeling: contribution to trophoblast invasion and placental development","volume":"185","author":"Agostinis","year":"2010","journal-title":"J Immunol (Baltimore, Md.: 1950)"},{"issue":"4\u20135","key":"10.1016\/j.autrev.2026.104151_bb0575","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1078\/0171-2985-00141","article-title":"C1q, autoimmunity and apoptosis","volume":"205","author":"Botto","year":"2002","journal-title":"Immunobiology"},{"issue":"9","key":"10.1016\/j.autrev.2026.104151_bb0580","doi-asserted-by":"crossref","first-page":"2629","DOI":"10.1016\/j.molimm.2007.12.025","article-title":"Decidual endothelial cells express surface-bound C1q as a molecular bridge between endovascular trophoblast and decidual endothelium","volume":"45","author":"Bulla","year":"2008","journal-title":"Mol Immunol"},{"key":"10.1016\/j.autrev.2026.104151_bb0585","doi-asserted-by":"crossref","first-page":"312","DOI":"10.3389\/fimmu.2014.00312","article-title":"Complement activation and regulation in preeclamptic placenta","volume":"5","author":"Lokki","year":"2014","journal-title":"Front Immunol"},{"issue":"12","key":"10.1016\/j.autrev.2026.104151_bb0590","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1038\/nrrheum.2016.186","article-title":"New insights into the immunopathogenesis of systemic lupus erythematosus","volume":"12","author":"Tsokos","year":"2016","journal-title":"Nat Rev Rheumatol"},{"key":"10.1016\/j.autrev.2026.104151_bb0595","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.molimm.2020.03.021","article-title":"Dysregulation of complement system during pregnancy in patients with preeclampsia: a prospective study","volume":"122","author":"He","year":"2020","journal-title":"Mol Immunol"},{"issue":"10","key":"10.1016\/j.autrev.2026.104151_bb0600","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.placenta.2008.07.008","article-title":"The C5b-9 membrane attack complex of complement activation localizes to villous trophoblast injury in vivo and modulates human trophoblast function in vitro","volume":"29","author":"Rampersad","year":"2008","journal-title":"Placenta"},{"issue":"5","key":"10.1016\/j.autrev.2026.104151_bb0605","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1111\/aji.12349","article-title":"Urinary excretion of C5b-9 is associated with the anti-angiogenic state in severe preeclampsia","volume":"73","author":"Guseh","year":"2015","journal-title":"Am J Reprod Immunol. (New York, N.Y.:1989)"},{"issue":"4","key":"10.1016\/j.autrev.2026.104151_bb0610","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1161\/HYPERTENSIONAHA.115.06783","article-title":"Placental growth factor administration abolishes placental ischemia-induced hypertension","volume":"67","author":"Spradley","year":"2016","journal-title":"Hypertension (Dallas, Tex.: 1979)"},{"issue":"5","key":"10.1016\/j.autrev.2026.104151_bb0615","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1161\/HYPERTENSIONAHA.112.194324","article-title":"Preeclampsia Is characterized by placental complement dysregulation","volume":"60","author":"Buurma","year":"2012","journal-title":"Hypertension (Dallas, Tex.:1979)"},{"issue":"6","key":"10.1016\/j.autrev.2026.104151_bb0620","first-page":"475","article-title":"Complement component C1q as potential diagnostic but not predictive marker of preeclampsia","volume":"76","author":"Agostinis","year":"2016","journal-title":"Am J Reproduct Immunol (New York, N.Y.: 1989)"},{"issue":"5","key":"10.1016\/j.autrev.2026.104151_bb0625","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.exphem.2016.01.005","article-title":"Direct evidence of complement activation in HELLP syndrome: a link to atypical hemolytic uremic syndrome","volume":"44","author":"Vaught","year":"2016","journal-title":"Exp Hematol"},{"issue":"9","key":"10.1016\/j.autrev.2026.104151_bib1036","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.34067\/KID.0000992021","article-title":"Quantitative alterations in complement alternative pathway and related genetic analysis in severe phenotype preeclampsia","volume":"2","author":"Alrahmani","year":"2021","journal-title":"Kidney360."},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb0630","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1182\/blood-2007-04-084533","article-title":"Membrane cofactor protein mutations in atypical hemolytic uremic syndrome (AHUS), fatal Stx-HUS, C3 glomerulonephritis, and the HELLP syndrome","volume":"111","author":"Fang","year":"2008","journal-title":"Blood"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb0635","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1111\/jcmm.13466","article-title":"Complement 5a-mediated trophoblasts dysfunction is involved in the development of pre-eclampsia","volume":"22","author":"Ma","year":"2018","journal-title":"J Cell Mol Med"},{"issue":"6","key":"10.1016\/j.autrev.2026.104151_bb0640","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1097\/AOG.0000000000002980","article-title":"Terminal complement activation in preeclampsia","volume":"132","author":"Burwick","year":"2018","journal-title":"Obstet Gynecol"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0645","doi-asserted-by":"crossref","first-page":"3048","DOI":"10.1038\/s41598-021-82733-z","article-title":"Complement and coagulation cascades activation is the main pathophysiological pathway in early-onset severe preeclampsia revealed by maternal proteomics","volume":"11","author":"Youssef","year":"2021","journal-title":"Sci Rep"},{"issue":"11","key":"10.1016\/j.autrev.2026.104151_bb0650","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s11906-017-0784-4","article-title":"The complement system and preeclampsia","volume":"19","author":"Regal","year":"2017","journal-title":"Curr Hypertens Rep"},{"issue":"3","key":"10.1016\/j.autrev.2026.104151_bb0655","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajog.2011.04.022","article-title":"Placental expression of endothelial and inducible nitric oxide synthase and nitric oxide levels in patients with HELLP syndrome","volume":"205","author":"Mazzanti","year":"2011","journal-title":"Am J Obstet Gynecol"},{"issue":"5 Pt 1","key":"10.1016\/j.autrev.2026.104151_bb0660","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1097\/01.AOG.0000126245.35811.2a","article-title":"Diagnosis, controversies, and management of the syndrome of hemolysis, elevated liver enzymes, and low platelet count","volume":"103","author":"Sibai","year":"2004","journal-title":"Obstet Gynecol"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb0665","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.cyto.2007.08.010","article-title":"Inflammatory cytokines patterns in the placenta of pregnancies complicated by HELLP (hemolysis, elevated liver enzyme, and low platelet) syndrome","volume":"40","author":"Tranquilli","year":"2007","journal-title":"Cytokine"},{"key":"10.1016\/j.autrev.2026.104151_bb0670","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.placenta.2016.09.012","article-title":"The placental component and obstetric outcome in severe preeclampsia with and without HELLP syndrome","volume":"47","author":"Weiner","year":"2016","journal-title":"Placenta"},{"issue":"8","key":"10.1016\/j.autrev.2026.104151_bb0675","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1161\/ATVBAHA.118.311150","article-title":"Neutrophil extracellular traps induce endothelial cell activation and tissue factor production through interleukin-1\u03b1 and cathepsin G","volume":"38","author":"Folco","year":"2018","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"6","key":"10.1016\/j.autrev.2026.104151_bb0680","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.12998\/wjcc.v9.i6.1259","article-title":"New indicators in evaluation of hemolysis, elevated liver enzymes, and low platelet syndrome: a case-control study","volume":"9","author":"Kang","year":"2021","journal-title":"World J Clin Cases"},{"issue":"10","key":"10.1016\/j.autrev.2026.104151_bb0690","doi-asserted-by":"crossref","first-page":"781","DOI":"10.2174\/1389201019666180925121254","article-title":"The role of agonistic autoantibodies to the angiotensin II type 1 receptor (AT1-AA) in pathophysiology of preeclampsia","volume":"19","author":"Campbell","year":"2018","journal-title":"Curr Pharm Biotechnol"},{"issue":"3","key":"10.1016\/j.autrev.2026.104151_bb0695","doi-asserted-by":"crossref","DOI":"10.1016\/j.autrev.2021.102763","article-title":"Interleukin 1\u03b1: a comprehensive review on the role of IL-1\u03b1 in the pathogenesis and treatment of autoimmune and inflammatory diseases","volume":"20","author":"Cavalli","year":"2021","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.autrev.2026.104151_bb0700","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.trsl.2022.03.001","article-title":"CD11b agonists offer a novel approach for treating lupus nephritis","volume":"245","author":"Villanueva","year":"2022","journal-title":"Transl Res"},{"issue":"11","key":"10.1016\/j.autrev.2026.104151_bb0705","doi-asserted-by":"crossref","first-page":"2322","DOI":"10.3109\/14767058.2012.694923","article-title":"The genetics of the alternative pathway of complement in the pathogenesis of HELLP syndrome","volume":"25","author":"Crovetto","year":"2012","journal-title":"J Matern Fetal Neonatal Med"},{"issue":"4","key":"10.1016\/j.autrev.2026.104151_bb0710","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1080\/10641955.2021.1983593","article-title":"Dysregulation of complement system in HELLP syndrome","volume":"40","author":"Chen","year":"2021","journal-title":"Hypertens Preg"},{"key":"10.1016\/j.autrev.2026.104151_bb0715","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.thromres.2016.03.014","article-title":"Are there any additional mechanisms for haemolysis in HELLP syndrome?","volume":"142","author":"Sabau","year":"2016","journal-title":"Thromb Res"},{"issue":"5","key":"10.1016\/j.autrev.2026.104151_bb0720","first-page":"1122","article-title":"Report of the American College of Obstetricians and Gynecologists\u2019 task force on hypertension in pregnancy","volume":"122","author":"Hypertension in pregnancy","year":"2013","journal-title":"Obstet Gynecol"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb0725","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.placenta.2012.11.014","article-title":"Eculizumab for the treatment of preeclampsia\/HELLP syndrome","volume":"34","author":"Burwick","year":"2013","journal-title":"Placenta"},{"issue":"9","key":"10.1016\/j.autrev.2026.104151_bb0730","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2018-228709","article-title":"Eculizumab, a novel potential treatment for acute kidney injury associated with preeclampsia\/HELLP syndrome","volume":"12","author":"Elabd","year":"2019","journal-title":"BMJ Case Rep"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb0735","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1093\/ckj\/sfz066","article-title":"Relative incidence of thrombotic thrombocytopenic purpura and haemolytic uraemic syndrome in clinically suspected cases of thrombotic microangiopathy","volume":"13","author":"Sch\u00f6nermarck","year":"2020","journal-title":"Clin Kidney J"},{"issue":"5","key":"10.1016\/j.autrev.2026.104151_bb0740","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1007\/s40620-021-01025-x","article-title":"Pregnancy-triggered atypical hemolytic uremic syndrome (AHUS): a global AHUS registry analysis","volume":"34","author":"Fakhouri","year":"2021","journal-title":"J Nephrol"},{"issue":"3","key":"10.1016\/j.autrev.2026.104151_bb0745","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1681\/ASN.2016090995","article-title":"Maternal and fetal outcomes of pregnancies in women with atypical hemolytic uremic syndrome","volume":"29","author":"Gaggl","year":"2018","journal-title":"J Am Soc Nephrol"},{"issue":"8","key":"10.1016\/j.autrev.2026.104151_bb0750","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1038\/s41581-021-00424-4","article-title":"Thrombotic microangiopathy in AHUS and beyond: clinical clues from complement genetics","volume":"17","author":"Fakhouri","year":"2021","journal-title":"Nat Rev Nephrol"},{"issue":"5","key":"10.1016\/j.autrev.2026.104151_bb0755","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1111\/jth.12796","article-title":"Impaired DNase1-mediated degradation of neutrophil extracellular traps is associated with acute thrombotic microangiopathies","volume":"13","author":"Jim\u00e9nez-Alc\u00e1zar","year":"2015","journal-title":"J Thromb Haemost"},{"issue":"24","key":"10.1016\/j.autrev.2026.104151_bb0760","doi-asserted-by":"crossref","first-page":"3818","DOI":"10.1182\/blood-2013-10-529982","article-title":"Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease","volume":"123","author":"Chen","year":"2014","journal-title":"Blood"},{"issue":"11","key":"10.1016\/j.autrev.2026.104151_bb0770","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1016\/j.molimm.2005.11.008","article-title":"Insights into hemolytic uremic syndrome: segregation of three independent predisposition factors in a large, multiple affected pedigree","volume":"43","author":"Esparza-Gordillo","year":"2006","journal-title":"Mol Immunol"},{"key":"10.1016\/j.autrev.2026.104151_bb0775","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1146\/annurev.med.59.060106.185110","article-title":"Complement regulatory genes and hemolytic uremic syndromes","volume":"59","author":"Kavanagh","year":"2008","journal-title":"Annu Rev Med"},{"issue":"5","key":"10.1016\/j.autrev.2026.104151_bb0780","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1681\/ASN.2010030308","article-title":"Pulling the trigger in atypical hemolytic uremic syndrome: the role of pregnancy","volume":"21","author":"Goodship","year":"2010","journal-title":"J Am Soc Nephrol"},{"issue":"23","key":"10.1016\/j.autrev.2026.104151_bb0785","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.1056\/NEJMoa1208981","article-title":"Terminal complement inhibitor eculizumab in atypical hemolytic-uremic syndrome","volume":"368","author":"Legendre","year":"2013","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0790","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.kint.2019.01.009","article-title":"Differential contribution of C5aR and C5b-9 pathways to renal thrombic microangiopathy and macrovascular thrombosis in mice carrying an atypical hemolytic syndrome-related factor H mutation","volume":"96","author":"Ueda","year":"2019","journal-title":"Kidney Int"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb0795","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1097\/AOG.0b013e31828e2612","article-title":"Eculizumab for atypical hemolytic uremic syndrome in pregnancy","volume":"122","author":"Ardissino","year":"2013","journal-title":"Obstet Gynecol"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0800","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1182\/bloodadvances.2023011972","article-title":"Management and follow-up of pregnancy-onset thrombotic thrombocytopenic purpura: the French experience","volume":"8","author":"B\u00e9ranger","year":"2024","journal-title":"Blood Adv"},{"issue":"6","key":"10.1016\/j.autrev.2026.104151_bb0805","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.3324\/haematol.2024.285391","article-title":"Acquired thrombotic thrombocytopenic purpura without detectable anti-ADAMTS13 antibodies: a possible underlying autoimmune mechanism","volume":"110","author":"Simon","year":"2025","journal-title":"Haematologica"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb0810","doi-asserted-by":"crossref","first-page":"638","DOI":"10.3324\/haematol.2022.280768","article-title":"ADAMTS13 conformation is closed in non-immune acquired thrombotic thrombocytopenic purpura of unidentified pathophysiology","volume":"108","author":"Joly","year":"2023","journal-title":"Haematologica"},{"issue":"5","key":"10.1016\/j.autrev.2026.104151_bb0815","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1111\/j.1365-2141.2008.07515.x","article-title":"Pregnancy-induced thrombocytopenia and TTP, and the risk of fetal death, in Upshaw-Schulman syndrome: a series of 15 pregnancies in 9 genotyped patients","volume":"144","author":"Fujimura","year":"2009","journal-title":"Br J Haematol"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb0820","doi-asserted-by":"crossref","first-page":"177.e1","DOI":"10.1016\/j.ajog.2021.02.018","article-title":"Unfolding the pathophysiology of congenital thrombotic thrombocytopenic purpura in pregnancy: lessons from a cluster of familial cases","volume":"225","author":"Miodownik","year":"2021","journal-title":"Am J Obstet Gynecol"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb0825","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1182\/blood-2014-02-553131","article-title":"Thrombotic thrombocytopenic purpura and pregnancy: presentation, management, and subsequent pregnancy outcomes","volume":"124","author":"Scully","year":"2014","journal-title":"Blood"},{"issue":"9","key":"10.1016\/j.autrev.2026.104151_bb0830","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1161\/ATVBAHA.117.309735","article-title":"Expression of ADAMTS13 in normal and abnormal placentae and its potential role in angiogenesis and placenta development","volume":"37","author":"Xiao","year":"2017","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"11","key":"10.1016\/j.autrev.2026.104151_bb0835","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1182\/blood.2023022277","article-title":"Thrombotic thrombocytopenic purpura: 100 years of research on Moschcowitz syndrome","volume":"144","author":"Cataland","year":"2024","journal-title":"Blood"},{"key":"10.1016\/j.autrev.2026.104151_bb0845","doi-asserted-by":"crossref","first-page":"17020","DOI":"10.1038\/nrdp.2017.20","article-title":"Thrombotic thrombocytopenic purpura","volume":"3","author":"Hovinga","year":"2017","journal-title":"Nat Rev Dis Primers"},{"issue":"6","key":"10.1016\/j.autrev.2026.104151_bb0850","first-page":"1320","article-title":"Von Willebrand factor-cleaving protease (ADAMTS13) activity in normal non-pregnant women, pregnant and post-delivery women","volume":"92","author":"S\u00e1nchez-Luceros","year":"2004","journal-title":"Thromb Haemost"},{"issue":"9","key":"10.1016\/j.autrev.2026.104151_bb0855","first-page":"e140","article-title":"High SFlt-1 (soluble Fms-like tyrosine kinase 1)\/PlGF (placental growth factor) ratio in pregnancy-onset thrombotic thrombocytopenic purpura","volume":"80","author":"B\u00e9ranger","year":"2023","journal-title":"Hypertension (Dallas, Tex.:1979)"},{"key":"10.1016\/j.autrev.2026.104151_bb0860","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.thromres.2021.04.021","article-title":"Early ADAMTS13 testing associates with pre-eclampsia occurrence in antiphospholipid syndrome","volume":"203","author":"Bitsadze","year":"2021","journal-title":"Thromb Res"},{"issue":"6","key":"10.1016\/j.autrev.2026.104151_bb0865","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1053\/j.ajkd.2015.06.032","article-title":"Treatment of congenital thrombotic thrombocytopenic Purpura with eculizumab","volume":"66","author":"Pecoraro","year":"2015","journal-title":"Am J Kidney Dis"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb0870","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.transci.2018.03.005","article-title":"Efficacy of eculizumab in severe ADAMTS13-deficient thrombotic thrombocytopenic purpura (TTP) refractory to standard therapies","volume":"57","author":"Vigna","year":"2018","journal-title":"Transfus Apher Sci"},{"issue":"4","key":"10.1016\/j.autrev.2026.104151_bb0875","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.thromres.2014.01.034","article-title":"Elevated plasma neutrophil elastase concentration is associated with disease activity in patients with thrombotic thrombocytopenic purpura","volume":"133","author":"Mikes","year":"2014","journal-title":"Thromb Res"},{"issue":"10","key":"10.1016\/j.autrev.2026.104151_bb0880","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1111\/jth.12369","article-title":"Complement activation and mortality during an acute episode of thrombotic thrombocytopenic purpura","volume":"11","author":"Wu","year":"2013","journal-title":"J Thromb Haemost"},{"issue":"5","key":"10.1016\/j.autrev.2026.104151_bb0885","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1681\/ASN.2005010086","article-title":"Complement factor H mutation in familial thrombotic thrombocytopenic purpura with ADAMTS13 deficiency and renal involvement","volume":"16","author":"Noris","year":"2005","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.autrev.2026.104151_bb0890","doi-asserted-by":"crossref","DOI":"10.1016\/j.clim.2020.108461","article-title":"Hydroxychloroquine inhibiting neutrophil extracellular trap formation alleviates hepatic ischemia\/reperfusion injury by blocking TLR9 in mice","volume":"216","author":"Zhang","year":"2020","journal-title":"Clin Immunol (Orlando, Fla)"},{"issue":"5","key":"10.1016\/j.autrev.2026.104151_bb0895","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.1093\/rheumatology\/keaa592","article-title":"Fetal safety of chloroquine and hydroxychloroquine use during pregnancy: a nationwide cohort study","volume":"60","author":"Andersson","year":"2021","journal-title":"Rheumatology (Oxford)"},{"issue":"11","key":"10.1016\/j.autrev.2026.104151_bb0900","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0271560","article-title":"Hydroxychloroquine reduces soluble Flt-1 secretion from human cytotrophoblast, but does not mitigate markers of endothelial dysfunction in vitro","volume":"17","author":"Kadife","year":"2022","journal-title":"PLoS One"},{"issue":"12","key":"10.1016\/j.autrev.2026.104151_bb0905","doi-asserted-by":"crossref","first-page":"2459","DOI":"10.1097\/HJH.0000000000003279","article-title":"Hydroxychloroquine reduces hypertension and soluble Fms-like kinase-1 in a N\u03c9-nitro-l-arginine methyl ester-induced preeclampsia rat model","volume":"40","author":"Choi","year":"2022","journal-title":"J Hypertens"},{"key":"10.1016\/j.autrev.2026.104151_bb0910","doi-asserted-by":"crossref","DOI":"10.1016\/j.jri.2023.103945","article-title":"Cell-free fetal DNA impairs trophoblast migration in a TLR9-dependent manner and can be reversed by hydroxychloroquine","volume":"157","author":"Le\u00f3n-Mart\u00ednez","year":"2023","journal-title":"J Reprod Immunol"},{"key":"10.1016\/j.autrev.2026.104151_bb0915","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1253667","article-title":"NETosis: an emerging therapeutic target in renal diseases","volume":"14","author":"Juha","year":"2023","journal-title":"Front Immunol"},{"key":"10.1016\/j.autrev.2026.104151_bb0920","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.cyto.2016.02.014","article-title":"Cyclosporin a significantly improves preeclampsia signs and suppresses inflammation in a rat model","volume":"81","author":"Hu","year":"2016","journal-title":"Cytokine"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb0925","doi-asserted-by":"crossref","DOI":"10.1080\/14767058.2023.2258254","article-title":"Immunosuppressive therapy with tacrolimus is a potential drug candidate for the prevention of unexplained or preeclamptic stillbirths with Th1-dominant immune states: a case series of five patients","volume":"36","author":"Hisano","year":"2023","journal-title":"J Maternal-Fetal Neonatal Med"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0930","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1038\/s41420-022-00913-w","article-title":"The possible involvement of CircRNA DMNT1\/P53\/JAK\/STAT in gestational diabetes mellitus and preeclampsia","volume":"8","author":"Bao","year":"2022","journal-title":"Cell Death Dis"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0935","doi-asserted-by":"crossref","DOI":"10.3892\/mmr.2020.11701","article-title":"HIF-3\u03b1 affects preeclampsia development by regulating EVT growth via activation of the Flt-1\/JAK\/STAT signaling pathway in hypoxia","volume":"23","author":"Qu","year":"2021","journal-title":"Mol Med Rep"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0940","doi-asserted-by":"crossref","first-page":"e44","DOI":"10.1097\/AOG.0000000000002708","volume":"132","author":"ACOG Committee Opinion No. 743: Low-Dose Aspirin Use During Pregnancy","year":"2018","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.autrev.2026.104151_bb0945","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.preghy.2018.05.009","article-title":"Activated protein C as disease-modifying therapy in antenatal preeclampsia: an open-label, single arm safety and efficacy trial","volume":"13","author":"von Dadelszen","year":"2018","journal-title":"Pregn Hypertens"},{"issue":"2S","key":"10.1016\/j.autrev.2026.104151_bb0950","article-title":"Low-molecular-weight heparin for prevention of preeclampsia and other placenta-mediated complications: a systematic review and Meta-analysis","volume":"226","author":"Cruz-Lemini","year":"2022","journal-title":"Am J Obstet Gynecol"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb0955","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.kint.2017.06.022","article-title":"A retrospective study of pregnancy-associated atypical hemolytic uremic syndrome","volume":"93","author":"Huerta","year":"2018","journal-title":"Kidney Int"},{"issue":"7","key":"10.1016\/j.autrev.2026.104151_bb0960","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1038\/nrneph.2016.71","article-title":"The role of neutrophils and NETosis in autoimmune and renal diseases","volume":"12","author":"Gupta","year":"2016","journal-title":"Nat Rev Nephrol"},{"issue":"11","key":"10.1016\/j.autrev.2026.104151_bb0965","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1056\/NEJMoa1502950","article-title":"Eculizumab in pregnant patients with paroxysmal nocturnal hemoglobinuria","volume":"373","author":"Kelly","year":"2015","journal-title":"N Engl J Med"},{"issue":"4","key":"10.1016\/j.autrev.2026.104151_bb0970","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.imbio.2014.11.003","article-title":"Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn","volume":"220","author":"Hallstensen","year":"2015","journal-title":"Immunobiology"},{"issue":"12","key":"10.1016\/j.autrev.2026.104151_bb0975","doi-asserted-by":"crossref","first-page":"2122","DOI":"10.1093\/ndt\/gfw314","article-title":"Atypical haemolytic uraemic syndrome and pregnancy: outcome with ongoing eculizumab","volume":"31","author":"Servais","year":"2016","journal-title":"Nephrol Dial Transpl"},{"issue":"3","key":"10.1016\/j.autrev.2026.104151_bb0980","first-page":"350","article-title":"Antibiotic prophylaxis in vaccinated eculizumab recipients who developed meningococcal disease","volume":"80","author":"Crew","year":"2020","journal-title":"J Inf Secur"},{"issue":"27","key":"10.1016\/j.autrev.2026.104151_bb0985","doi-asserted-by":"crossref","first-page":"734","DOI":"10.15585\/mmwr.mm6627e1","article-title":"High risk for invasive meningococcal disease among patients receiving eculizumab (Soliris) despite receipt of meningococcal vaccine","volume":"66","author":"McNamara","year":"2017","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"1","key":"10.1016\/j.autrev.2026.104151_bb0990","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s12882-020-02190-0","article-title":"Efficacy and safety of the Long-acting C5 inhibitor ravulizumab in patients with atypical hemolytic uremic syndrome triggered by pregnancy: a subgroup analysis","volume":"22","author":"G\u00e4ckler","year":"2021","journal-title":"BMC Nephrol"},{"issue":"4","key":"10.1016\/j.autrev.2026.104151_bb0995","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0195909","article-title":"Design and preclinical characterization of ALXN1210: a novel anti-C5 antibody with extended duration of action","volume":"13","author":"Sheridan","year":"2018","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb1000","article-title":"Pregnancy-associated atypical hemolytic uremic syndrome successfully treated with ravulizumab: a case report","volume":"16","author":"Miyazaki","year":"2024","journal-title":"Cureus"},{"issue":"20\u221222","key":"10.1016\/j.autrev.2026.104151_bb1005","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1080\/1750743X.2024.2433410","article-title":"Crovalimab in the paroxysmal nocturnal hemoglobinuria treatment landscape","volume":"16","author":"R\u00f6th","year":"2024","journal-title":"Immunotherapy"},{"key":"10.1016\/j.autrev.2026.104151_bb1010","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1146\/annurev-med-042921-102405","article-title":"Expansion of anticomplement therapy indications from rare genetic disorders to common kidney diseases","volume":"75","author":"Miwa","year":"2024","journal-title":"Annu Rev Med"},{"issue":"18","key":"10.1016\/j.autrev.2026.104151_bb1015","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1080\/14656566.2024.2404110","article-title":"Iptacopan for the treatment of paroxysmal nocturnal hemoglobinuria","volume":"25","author":"de Castro","year":"2024","journal-title":"Expert Opin Pharmacother"},{"key":"10.1016\/j.autrev.2026.104151_bb1020","doi-asserted-by":"crossref","first-page":"1297352","DOI":"10.3389\/fimmu.2023.1297352","article-title":"Development and characterization of narsoplimab, a selective MASP-2 inhibitor, for the treatment of lectin-pathway-mediated disorders","volume":"14","author":"Dudler","year":"2023","journal-title":"Front Immunol"},{"key":"10.1016\/j.autrev.2026.104151_bb1025","doi-asserted-by":"crossref","DOI":"10.1056\/NEJMe2608684","article-title":"Retraction: Jayne DRW et al. Avacopan for the treatment of ANCA-associated vasculitis, N Engl J Med 2021;384:599-609","author":"Rubin","year":"2026","journal-title":"New Engl J Med"},{"issue":"2","key":"10.1016\/j.autrev.2026.104151_bb1030","article-title":"Unexpected adverse event caused by avacopan: a case of drug-induced hypersensitivity syndrome in microscopic polyangiitis","volume":"9","author":"Nibu","year":"2025","journal-title":"Modern Rheumatol Case Rep"},{"key":"10.1016\/j.autrev.2026.104151_bb1035","doi-asserted-by":"crossref","first-page":"2166","DOI":"10.3389\/fimmu.2019.02166","article-title":"Complement inhibitors in clinical trials for glomerular diseases","volume":"10","author":"Zipfel","year":"2019","journal-title":"Front Immunol"}],"container-title":["Autoimmunity Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568997226001655?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568997226001655?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T16:00:51Z","timestamp":1792857651000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1568997226001655"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":208,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["S1568997226001655"],"URL":"https:\/\/doi.org\/10.1016\/j.autrev.2026.104151","relation":{},"ISSN":["1568-9972"],"issn-type":[{"value":"1568-9972","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Aberrant neutrophil and complement activation in thrombotic microangiopathies in pregnancy - Is there a missing link?","name":"articletitle","label":"Article Title"},{"value":"Autoimmunity Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.autrev.2026.104151","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"104151"}}